Patents by Inventor Kazuya Yamano
Kazuya Yamano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7425446Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: GrantFiled: November 28, 2005Date of Patent: September 16, 2008Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Patent number: 7393683Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: GrantFiled: November 28, 2005Date of Patent: July 1, 2008Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Patent number: 7332301Abstract: Using the proteins of the present invention, DNAs encoding the proteins, and antibodies recognizing the proteins, detection methods for diseases relating to the novel insulin-like growth factor binding proteins of the present invention, as well as diagnostic agents, preventive agents, and therapeutic agents for diseases relating to the proteins of the present invention can be provided.Type: GrantFiled: March 30, 2006Date of Patent: February 19, 2008Assignee: Kyowa Haakko Kogyo Co. Ltd.Inventors: Kazuya Yamano, Susumu Sekine, Mitsuo Satoh, Toshio Ota, Akiko Furuya, Kenji Shibata, Yuki Kobayashi, Miho Takebayashi, Yusuke Nakamura, Sumio Sugano
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Publication number: 20070074926Abstract: A power assist mechanism is provided that assists operation of a steering mechanism when receiving a pressurized hydraulic fluid. A hydraulic pump feeds the power assist mechanism with the pressurized hydraulic fluid when driven. An electric motor drives the hydraulic pump. A battery unit is provided for energizing the electric motor. A control unit is provided for controlling the electric power from the battery unit to the electric motor. The battery unit comprises a plurality of lead-acid batteries that are connected in series. Each lead-acid battery comprises a spirally wound positive plate, a spirally wound negative plate, a spirally wound insulating plate that is spirally wound and sandwiched between the positive and negative plates, a battery case that puts therein the spirally wound positive, negative and insulating plates and an electrolyte that is provided in the battery case.Type: ApplicationFiled: July 17, 2006Publication date: April 5, 2007Inventors: Toru Takahashi, Toshimitsu Sakaki, Tadaharu Yokota, Kazuya Yamano, Kyoko Honbo, Masanori Sakai
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Publication number: 20070032937Abstract: In vehicular driving control apparatus and method, a steering assistance force provided for steerable road wheels of the vehicle in a direction at which a sideslip angle is decreased when a vehicular sideslip angle which is a difference between a forwarding direction of the vehicle and a steering direction of a steering wheel of the vehicle is detected and a vehicular oversteer state is detected, and thereafter, each of road wheels of the vehicle is controlled to decrease the sideslip angle when the steering assistance force is provided in a direction at which the vehicular sideslip angle is decreased and when the sideslip angle is equal to or larger than a predetermined value.Type: ApplicationFiled: July 19, 2006Publication date: February 8, 2007Inventors: Naoshi Yamaguchi, Mitsuo Sasaki, Kazuya Yamano, Toru Takahashi, Motohiro Higuma
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Publication number: 20070010009Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: April 13, 2006Publication date: January 11, 2007Applicant: KYOWA HAKKO KOGYO CO., LTDInventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060216739Abstract: Using the proteins of the present invention, DNAs encoding the proteins, and antibodies recognizing the proteins, detection methods for diseases relating to the novel insulin-like growth factor binding proteins of the present invention, as well as diagnostic agents, preventive agents, and therapeutic agents for diseases relating to the proteins of the present invention can be provided.Type: ApplicationFiled: March 30, 2006Publication date: September 28, 2006Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Kazuya Yamano, Susumu Sekine, Mitsuo Satoh, Toshio Ota, Akiko Furuya, Kenji Shibata, Yuki Kobayashi, Miho Takebayashi, Yusuke Nakamura, Sumio Sugano
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Patent number: 7071160Abstract: Using the proteins of the present invention, DNAs encoding the proteins, and antibodies recognizing the proteins, detection methods for diseases relating to the novel insulin-like growth factor binding proteins of the present invention, as well as diagnostic agents, preventive agents, and therapeutic agents for diseases relating to the proteins of the present invention can be provided.Type: GrantFiled: June 15, 2001Date of Patent: July 4, 2006Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Kazuya Yamano, Susumu Sekine, Mitsuo Satoh, Toshio Ota, Akiko Furuya, Kenji Shibata, Yuki Kobayashi, Miho Takebayashi, Yusuke Nakamura, Sumio Sugano
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Publication number: 20060078991Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: November 28, 2005Publication date: April 13, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060078990Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: November 28, 2005Publication date: April 13, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060064781Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: October 3, 2005Publication date: March 23, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060063254Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: September 6, 2005Publication date: March 23, 2006Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20060024793Abstract: The present invention provides a process for producing an antithrombin III composition comprising an antithrombin III molecule having complex type N-glycoside-linked sugar chains, wherein the complex type N-glycoside-linked sugar chains have a structure in which fucose is not bound to N-acetylglucosamine in the reducing end in the sugar chains.Type: ApplicationFiled: October 7, 2004Publication date: February 2, 2006Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Tsuyoshi Yamada, Mitsuo Satoh, Yutaka Kanda, Kazuya Yamano
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Publication number: 20060021071Abstract: The present invention provides a cell capable of controlling the sugar chain structure of a glycoprotein which is a producing protein, that is, a cell capable of producing a glycoprotein having high physiological activity; a process for producing a glycoprotein using the cell; a glycoprotein produced by the process; and use thereof.Type: ApplicationFiled: October 7, 2004Publication date: January 26, 2006Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Mitsuo Satoh, Shigeru Iida, Katsuhiro Mori, Miho Urakubo, Reiko Kamochi, Kazuya Yamano
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Publication number: 20050262593Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-modulated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: ApplicationFiled: May 18, 2005Publication date: November 24, 2005Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20050216958Abstract: A cell in which genome is modified so as to have a more decreased or deleted activity of an enzyme relating to modification of a sugar chain in which 1-position of fucose is bound to 6-position of N-acetylglucosamine in the reducing end through ?-bond in a complex N-glycoside-linked sugar chain than its parent cell, and a process for producing an antibody composition using the cell.Type: ApplicationFiled: May 12, 2005Publication date: September 29, 2005Applicant: Kyowa Hakko Kogyo Co., LtdInventors: Naoko Yamane, Mitsuo Satoh, Katsuhiro Mori, Kazuya Yamano
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Patent number: 6946292Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.Type: GrantFiled: October 9, 2001Date of Patent: September 20, 2005Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
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Publication number: 20050016791Abstract: A steering control system for controlling turning of steered road wheels of a motor vehicle in accordance with steering of a steering wheel, comprises a steering angle sensor that detects a steering angle by which the steering wheel is turned; an actuator that turns the steered road wheels when operated; a vehicle operation condition sensor that detects an operation condition of the motor vehicle; a target value determining section that determines a steered angle target value of the steered road wheels in accordance with the steering angle detected by the steering angle sensor and the vehicle operation condition detected by the vehicle operation condition sensor; and an actuator drive circuit that drives the actuator in accordance with the steered angle target value.Type: ApplicationFiled: July 23, 2004Publication date: January 27, 2005Inventors: Naoto Fukushima, Toshiaki Nakamura, Kohtaro Shiino, Satoshi Taniuchi, Kazuya Yamano, Minoru Masaki
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Publication number: 20040132140Abstract: A process for producing an antibody composition using a cell, which comprises using a cell resistant to a lectin which recognizes a sugar chain in which 1-position of fucose is bound to 6-position of N-acetylglucosamine in the reducing end through &agr;-bond in a complex N-glycoside-linked sugar chain, and a cell used for the process.Type: ApplicationFiled: April 9, 2003Publication date: July 8, 2004Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Mitsuo Satoh, Reiko Kamachi, Yutaka Kanda, Katsuhiro Mori, Kazuya Yamano, Satoko Kinoshita, Shigeru Iida
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Publication number: 20040110704Abstract: A cell in which genome is modified so as to have a more decreased or deleted activity of an enzyme relating to modification of a sugar chain in which 1-position of fucose is bound to 6-position of N-acetylglucosamine in the reducing end through &agr;-bond in a complex N-glycoside-linked sugar chain than its parent cell, and a process for producing an antibody composition using the cell.Type: ApplicationFiled: April 9, 2003Publication date: June 10, 2004Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Naoko Yamane, Mitsuo Satoh, Katsuhiro Mori, Kazuya Yamano