Abstract: Materials and Methods for identifying lignin regulatory region-regulatory protein associations are disclosed. Materials and methods for modulating lignin accumulation are also disclosed. In addition, methods and materials for modulating (e.g., increasing or decreasing) the level of a component (e.g., protein, oil, lignin, carbon, a carotenoid, or a triterpenoid) in plants are disclosed.

Abstract: The invention is directed to methods and kits that allow for classification of colorectal cancer cells according to genomic profiles, and methods of diagnosing, predicting clinical outcomes, and stratifying patient populations for clinical testing and treatment using the same.

Abstract: The invention is directed to methods and kits that allow for classification of non-small cell lung carcinoma tumors and cell lines according to genomic profiles, and methods of diagnosing, predicting clinical outcomes, and stratifying patient populations for clinical testing and treatment using the same.

Abstract: The invention is directed to methods and kits that allow for classification of malignant melanoma cells according to genomic profiles, and methods of diagnosing, predicting clinical outcomes, and stratifying patient populations for clinical testing and treatment using the same.

Abstract: Materials and methods for modulating (e.g., increasing or decreasing) lignin content in plants are disclosed. For example, nucleic acids encoding lignin-modulating polypeptides are disclosed as well as methods for using such nucleic acids to generate transgenic plants having a modulated lignin content.

Abstract: The present invention relates to compounds of Formula I: wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR5. The compounds can be used, for example, to treat diseases associated with chemokine receptor expression or activity such as inflammatory diseases, immune diseases and viral infections.

Abstract: There are provided methods and systems for precisely controlling the surfactant concentration and character of ferroelectric nanoparticles in a ferroelectric liquid crystal dispersion. In an aspect, the invention provides an efficient FTIR technique to characterize the status and measure the distribution of the surfactant in ferroelectric particle dispersion. This allows for establishing a reproducible fabrication process for ferroelectric nanoparticle liquid crystal dispersions. The methods also maintain the nanoparticles ferroelectricity, which is provided by the addition of surfactant during a comminution process. The invention therefore optimizes both the milling time (to achieve small particle size and narrow size distribution) and surfactant concentration (to maintain the ferroelectricity during milling).

Abstract: An integrated method for preparing a fuel cell membrane-catalyst coated membrane electrode, comprising preparation a proto exchange membrane and preparing catalyst coated membrane electrode, characterized in that: the proton exchange membrane is prepared by casting, dipping or spraying proton exchange resin solution (401) to obtain a precursor without post-treatment; the catalyst coated membrane electrode (CCM), is produced by directly coating electrode slurry on both sides of precursor of proton exchange membrane using a method chosen from screen-printing, spraying or brushing, and drying to obtain a CCM precursor with stable morphology; and treating the CCM precursor with ion transformation, heat and activation.

Abstract: The present disclosure is directed to compositions comprising templated nanoconjugates and methods of their use.

Abstract: Provided is a liquid crystal (LC) device and method thereof. The device comprises (i) a body of liquid crystal, (ii) a first layer comprising a first material, and (iii) a second layer comprising a second material; wherein the first layer is located between the body of liquid crystal and the second layer; the first layer alone aligns the liquid crystal in a first orientation; the second layer alone aligns the liquid crystal in a second orientation; and the first orientation is different from the second orientation. With optimized first layer thickness, the invention can be used in sensor applications to improve detection sensitivity, and in LCD applications with enhanced control over LC pretilt transition.

Abstract: Embodiments of the present invention disclose a method, an apparatus, and a system advertisement delivery. The method includes: receiving a user request for visiting a local WEB page of a home gateway, where the user request is sent by a user terminal; and obtaining an address of advertisement data corresponding to a stored advertisement parameter, assembling the address of the advertisement data into data on the local WEB page of the home gateway according to the advertisement parameter, and sending the data into which the address of the advertisement data is assembled on the local WEB page of the home gateway.

Abstract: The present invention relates to compounds of Formula I: wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR5. The compounds can be used, for example, to treat diseases associated with chemokine receptor expression or activity such as inflammatory diseases, immune diseases and viral infections.

Abstract: Methods and kits for predicting the sensitivity of a cancer to treatment with a targeted tyrosine kinase inhibitor are disclosed.

Abstract: A video coding/decoding system builds implied reference frames from a plurality of reference frames developed during coding. Coded data of reference pictures are decoded and stored in a reference picture cache. An implied reference frame may be derived from a plurality of reference frames and may be stored in the reference picture cache. Thereafter, coding of new input data may proceed using the implied reference frame as a source of prediction. The method may be used to identify visual elements such as background elements that may persist in video over a longer period that can be captured by the system under conventional reference frames assembly and eviction. Implied reference frames may be built at both an encoder and a decoder to serve as sources of prediction.

Abstract: The present disclosure relates generally to the evaluation and/or treatment of a subject having or suspected of having a neoplastic condition, and in particular to the use of biomarkers for identifying patients receptive to a certain drug therapy, and which permit monitoring of patient response to such therapy.

Abstract: Provided herein are methods for the diagnosis, or management of liver diseases, e.g. hepatocellular carcinoma, using profiles of the miRNAs determined from cellular or acellular body fluids.

Abstract: Provided herein are methods for the diagnosis, staging, prognosis, or management of liver disease, e.g. chronic liver disease, and other diseases using profiles of the ubiquitin-proteasome system determined from acellular body fluids or cell-containing samples. Further provided are methods of predicting response to therapy in certain populations of patients with liver disease.