Abstract: A major object of the present invention is to provide a volume hologram transfer foil that gives a volume hologram laminate higher in antiforgery function. The present invention achieves the object by providing a volume hologram transfer foil comprising: a substrate, a volume hologram layer carrying a recorded volume hologram that is formed on the substrate, and an image forming layer carrying a formed image and a heat seal layer containing a thermoplastic resin that are formed on the volume hologram layer, and comprising no reflective layer having a function to reflect light.

Abstract: A major object of the present invention is to provide a volume hologram transfer foil that gives a volume hologram laminate higher in antiforgery function. The present invention achieves the object by providing a volume hologram transfer foil comprising: a substrate, a volume hologram layer carrying a recorded volume hologram that is formed on the substrate, and an image forming layer carrying a formed image and a heat seal layer containing a thermoplastic resin that are formed on the volume hologram layer, and comprising no reflective layer having a function to reflect light.

Abstract: A method for efficiently preparing blood cells, such as mature megakaryocytes and platelets, from iPS cells is achieved in an in vitro culture system. A sac-like structure encloses hematopoietic progenitor cells, which is obtained by inoculating iPS cells onto feeder cells and then culturing the iPS cells under conditions suitable for inducing the differentiation of hematopoietic progenitor cells. Moreover, a method for producing various types of blood cells, comprises culturing hematopoietic progenitor cells enclosed in the sac-like structure under conditions suitable for inducing the differentiation of blood cells. Furthermore, a method for producing various types of blood cells, particularly megakaryocytes and platelets, is achieved without involving the sac-like structure.

Abstract: It is an object of the present invention to provide a method for efficient differentiation into blood cells. Specifically, in the present invention, when blood cells are produced from pluripotent stem cells such as ES cells or iPS cells in vitro, the cells are cultured under a low oxygen partial pressure to increase the efficiency of differentiating the pluripotent stem cells into hematopoietic progenitor cells, erythroid progenitor cells, and the like, so as to increase the number of finally obtained, desired blood cells.

Abstract: A primary object of the invention is to provide a volume hologram transfer foil which has good foil cutting characteristics and is used to manufacture a volume hologram laminate by transferring a volume hologram layer to an adherend by thermocompression. The above problem is solved by a volume hologram transfer foil comprising a base material, a protective layer formed on the base material, a volume hologram layer formed on the protective layer and having a volume hologram recorded, and a heat seal layer formed on the volume hologram layer, wherein the protective layer contains a hard coat component formed of an ionizing radiation-curable resin, a rupture elongation control component which improves the rupture elongation of the protective layer, and a foil cutting characteristic control component which has a thermal expansion coefficient different from those of the hard coat component and rupture elongation control component and is incompatible with the two components.

Abstract: A composition for maintaining a function of platelets, the composition comprising, as an active ingredient, a compound represented by the following general formula (I) or a salt thereof, or a solvate thereof: wherein X represents a phenylene group; Y represents any one of a hydrogen atom and —(CH2)mR1; wherein m represents an integer of any one of 0 to 4; and R1 is any one of —NR5COR2, —NR5SO2R2, and —NR3R4; wherein R2 represents any one of a C1 to C6 alkyl group, an aryl group, a C1 to C6 alkoxy group, and the like; R3 and R4 represent a C1 to C6 alkyl group or the like; and R5 represents any one of a hydrogen atom, a C1 to C6 alkyl group, and the like; and Z represents any one of a hydrogen atom and a C1 to C6 alkyl group.

Abstract: The present invention provides a lengthy volume hologram layer transfer foil capable of transferring a volume hologram layer continuously to a specified position of a transfer-receiving member. The above problem can be solved by a lengthy volume hologram layer transfer foil according to the present invention, the transfer foil is formed lengthwise and comprises: a substrate, a volume hologram layer which is formed on the substrate and in which a volume hologram is recorded, and a heat seal layer which is formed on the volume hologram layer and which contains a thermoplastic resin, the transfer foil being characterized in that it is provided with a cut portion formed so as to penetrate through the heat seal layer and to cut at least a part of the volume hologram layer, on at least a part of the full width in a direction perpendicular to the longitudinal direction thereof.

Abstract: The present invention has an object of providing a method for producing specific cells by amplifying cells in a desired differentiation stage. The present invention provides a method for producing specific cells by inducing differentiation of cells, wherein an oncogene is forcibly expressed in cells in a desired differentiation stage to amplify the cells in the desired differentiation stage. The present invention also provides a method for producing specific cells, wherein oncogene-induced senescence (OIS) which is induced by the oncogene expressed in the cells in the desired differentiation stage is suppressed.

Abstract: An object of the present invention is to provide a sac-like structure enclosing hematopoietic progenitor cells and a method for preparing the sac-like structure as well as a method for efficiently preparing blood cells such as mature megakaryocytes and platelets from the sac-like structure. The present invention provides a sac-like structure enclosing hematopoietic progenitor cells, the sac-like structure being obtained by plating ES cells onto feeder cells and culturing the ES cells under suitable conditions for inducing hematopoietic progenitor cell differentiation. Moreover, the present invention provides a method for producing various blood cells, the method comprising further culturing hematopoietic progenitor cells enclosed in the sac-like structure under suitable conditions for inducing blood cell differentiation.

Abstract: The present invention relates to a method for fluorescent image formation which can form a highly scratch-resistant fluorescent full-color image using a colorless fluorescent agent and can freely regulate the tone of color mixture of a combination of two or more fluorescent colors in order to impart, to articles, a higher level of forgery preventive function than a prior art technique and a print having a high level of forgery preventive function. The invention characterized in that fluorescent inks are provided that are substantially colorless upon visible light irradiation and contain organic fluorescent agents which, upon ultraviolet light irradiation, emit fluorescences in a visible region, and that two or more fluorescent inks, which emit fluorescences having mutually different color tones, are deposited on a printing face in its image formation region according to information on an image to be printed in a dot matrix manner so that dots of one color do not overlap with dots of another color.

Abstract: An object of the present invention is to provide an authenticity indicator that cannot be easily forged, that is clearly distinguishable, and that can be elaborately designed. An authenticity indicator 101 is in the form of a sheet and can be checked for its authenticity by observing the light reflected from it. The authenticity indicator comprises a first reflective layer 12 comprising a reflective area 12a that reflects specified light, and a second reflective layer 15 that reflects specified light. The reflective area of the first reflective layer has a cholesteric liquid crystalline structure. The second reflective layer comprises a volume hologram.

Abstract: It is an object of the present invention to provide a method for efficiently preparing blood cells, such as mature megakaryocytes and platelets, from iPS cells in an in vitro culture system. The present invention provides a sac-like structure enclosing hematopoietic progenitor cells, which is obtained by inoculating iPS cells onto feeder cells and then culturing the iPS cells under conditions suitable for inducing the differentiation of hematopoietic progenitor cells. Moreover, the present invention also provides a method for producing various types of blood cells, which comprises culturing hematopoietic progenitor cells enclosed in the sac-like structure under conditions suitable for inducing the differentiation of blood cells. Furthermore, the present invention also provides a method for producing various types of blood cells, particularly megakaryocytes and platelets, without involving the sac-like structure.

Abstract: An object of the present invention is to provide a sac-like structure enclosing hematopoietic progenitor cells and a method for preparing the sac-like structure as well as a method for efficiently preparing blood cells such as mature megakaryocytes and platelets from the sac-like structure. The present invention provides a sac-like structure enclosing hematopoietic progenitor cells, the sac-like structure being obtained by plating ES cells onto feeder cells and culturing the ES cells under suitable conditions for inducing hematopoietic progenitor cell differentiation. Moreover, the present invention provides a method for producing various blood cells, the method comprising further culturing hematopoietic progenitor cells enclosed in the sac-like structure under suitable conditions for inducing blood cell differentiation.

Abstract: The invention provides (1) a volume hologram transfer foil comprising a substrate and protective layer, a volume hologram layer and a heat seal layer stacked on the substrate in this order, wherein a multilayer structure comprising the protective layer, the volume hologram layer and the heat seal layer in this order is releasable from the substrate, and (2) a volume hologram transfer foil wherein the above protective layer is used as a heat seal layer. The heat seal layer comprises a polyester resin having a glass transition temperature of ?10° C. to ?30° C. With the invention, thermo-compression adhesion of the volume hologram layer to any application member, especially a polyester resin card is improved, so that the invention provides a volume hologram transfer foil useful for prevention of illegal copying, and a volume hologram multilayer structure formed using such a transfer foil.

Abstract: A method of producing a volume hologram laminate which can regenerate a hologram image in an arbitrary wavelength by a simple process. The method uses a volume hologram forming substrate which includes: a substrate, a volume hologram layer formed on the substrate and containing a photopolymerizable material, a resin layer, formed on the substrate so as to contact to the volume hologram layer, containing a resin and a polymerizable compound. The producing method includes processes of: a hologram recording process to record a volume hologram to the volume hologram layer, a substance transit process of transiting the polymerizable compound to the volume hologram layer, and an after-treatment process of polymerizing the polymerizable compound.

Abstract: This invention provides a hologram thermal transfer sheet that can realize thermal transfer treatment with high efficiency. The thermal transfer sheet comprises a base material sheet and a transparent transfer layer provided separably on the base material sheet, characterized in that a hologram layer is provided on at least a part of the transparent transfer layer. There are also provided a process for producing the thermal transfer sheet and an image formed material produced by the transfer of this thermal transfer sheet.

Abstract: The invention provides a process capable of fabricating a cholesteric liquid crystal medium having a volume hologram with efficiency yet without recourse to complicated steps such as an alignment step. This is achievable as follows. A volume hologram layer is formed on a substrate, and a cholesteric liquid crystal layer is then formed on another substrate comprising a center substrate film that is subjected to bondable treatment. The volume hologram layer is applied to the center substrate film that is subjected to bondable treatment, and placed in a state where the volume hologram layer and cholesteric liquid crystal layer are laminated together via the substrate. The substrate is peeled off the volume hologram layer, and an adhesive layer is formed on the surface of the volume hologram layer off which the substrate is peeled off, followed by the provision of the substrate on the adhesive layer.

Abstract: The invention provides a process capable of fabricating a cholesteric liquid crystal medium having a volume hologram with efficiency yet without recourse to complicated steps such as an alignment step. This is achievable as follows. A volume hologram layer is formed on a substrate, and a cholesteric liquid crystal layer is then formed on another substrate comprising a center substrate film that is subjected to bondable treatment. The volume hologram layer is applied to the center substrate film that is subjected to bondable treatment, and placed in a state where the volume hologram layer and cholesteric liquid crystal layer are laminated together via the substrate. The substrate is peeled off the volume hologram layer, and an adhesive layer is formed on the surface of the volume hologram layer off which the substrate is peeled off, followed by the provision of the substrate on the adhesive layer.

Abstract: The present invention relates to a method for fluorescent image formation which can form a highly scratch-resistant fluorescent full-color image using a colorless fluorescent agent and can freely regulate the tone of color mixture of a combination of two or more fluorescent colors in order to impart, to articles, a higher level of forgery preventive function than a prior art technique and a print having a high level of forgery preventive function. The invention characterized in that fluorescent inks are provided that are substantially colorless upon visible light irradiation and contain organic fluorescent agents which, upon ultraviolet light irradiation, emit fluorescences in a visible region, and that two or more fluorescent inks, which emit fluorescences having mutually different color tones, are deposited on a printing face in its image formation region according to information on an image to be printed in a dot matrix manner so that dots of one color do not overlap with dots of another color.

Abstract: The invention provides a process capable of fabricating a cholesteric liquid crystal medium having a volume hologram with efficiency yet without recourse to complicated steps such as an alignment step. This is achievable as follows. A volume hologram layer is formed on a substrate, and a cholesteric liquid crystal layer is then formed on another substrate comprising a center substrate film that is subjected to bondable treatment. The volume hologram layer is applied to the center substrate film that is subjected to bondable treatment, and placed in a state where the volume hologram layer and cholesteric liquid crystal layer are laminated together via the substrate. The substrate is peeled off the volume hologram layer, and an adhesive layer is formed on the surface of the volume hologram layer off which the substrate is peeled off, followed by the provision of the substrate on the adhesive layer.