Abstract: The present invention relates to a complex comprising acidic sophorolipid and curcumin ((SL(A)+Cur), wherein, curcumin is solubilized and nano-encapsulated in acidic sophorolipid to improve the water solubility, stability and bioavailability of curcumin in order to enhance its therapeutic activity. Further, the invention provides pharmaceutical compositions comprising the present complex and methods to treat cancer in a subject using the said composition.

Abstract: A network-to-network interface (NNI) gateway for inter-communication between a Push-to-Talk-over-Cellular (PoC) system in a first wireless network and a Land Mobile Radio (LMR) system in a second wireless network. The PoC system performs a PoC call session for PoC mobile units in the first wireless network. The LMR system performs a Push-to-Talk (PTT) call session for LMR subscriber units in the second wireless network. Both the PoC and PIT call sessions comprise an instant two-way half-duplex voice call within a group of the PoC mobile units and/or LMR subscriber units. The gateway bridges the LMR system to the PoC system, such that the PoC system is exposed to the LMR system as an emulated LMR system, the LMR system is exposed to the PoC system as an emulated PoC system, and calls are placed across the first and second wireless networks between the PoC mobile units and LMR subscriber units.

Abstract: An external fixation frame for correcting a bone deformity includes a first fixation ring and a second fixation ring. A posterior adjustable length strut couples a posterior portion of the first fixation ring to a posterior portion of the second fixation ring and has universal joint. Medial and lateral adjustable length struts couples medial and lateral portions of the first fixation ring to medial and lateral portions of the second fixation ring respectively, each of the medial and lateral adjustable length struts including a constrained hinge joint. The fixation frame also includes a half ring hingedly coupled to the second fixation ring, and an anterior adjustable length strut coupling an anterior portion of the first fixation ring to the half ring.

Abstract: A method and system is provided for transforming mesh for simulating manufacturing processes and products. The present application provides a method and system for transforming mesh for simulating at least one manufacturing process and at least one product comprises of selecting one or more transformation rules; executing the selected one or more transformation rules for obtaining a transformation chain; and executing the obtained transformation chain for obtaining a transformed mesh data using a transformation engine.

Abstract: An external fixation system includes top and bottom fixation plates that may be connected to fragments of a bone. At least one y-shaped strut attaches the two fixation plates. Each y-shaped strut has first, second and third telescopic struts coupled at a connector joint. The first strut member is coupled to the top fixation plate and the second and third strut members are coupled to the bottom fixation plate. Each strut member may include a joint and may also include an actuation unit connecting the particular strut member to the top or bottom fixation plate. Rotation of a head portion of the actuation unit causes rotation of a threaded rod, causing adjustment in the length of the respective strut member. As the lengths of the strut members change, the joints may reposition, leading to the top fixation plate becoming repositioned with respect to the bottom fixation plate.

Abstract: An external fixator system comprising at least two fixation plates which are arranged at a distance to each another, at least one adjustable length strut having a first end region and a second end region which are in connection with the fixation plates and at least one actuation unit to adjust the length of the strut in order to adjust the distance and/or orientation between the fixation plates. The actuation unit is in a fixed connection with at least one of the fixation plates as well as with at least one of the end regions of the respective strut in order to connect the strut with the fixation plate. The actuation unit comprises a feedback unit which provides the user with a feedback concerning the degree of the actuation.

Abstract: The present invention provides a novel, scalable and industrially viable downstream process for purification of recombinant human G-CSF.

Abstract: Compositions, methods and kits are provided for treating complement related disorders in a subject with protein in combination having protein fusions of at least two of a CD46 protein, a CD55 protein and a CD59 protein or with a recombinant chimeric protein having at least two of a CD46 protein, a CD55 protein and a CD59 protein or with nucleic acids encoding these proteins. The composition negatively modulates classical and alternative complement pathways thereby treating complement related disorder such as macular degeneration, age-related macular degeneration, diabetic retinopathy, inflammatory bowel disease, thyroiditis, cryoglobulinaemia, fetal loss, organ graft rejection, cancer, etc.

Abstract: The present invention deals with a mycoherbicidal isolate of Setosphaeria monoceras sp. or extracts obtained therefrom, useful for the control of Water hyacinth. The present invention also discloses biological control compositions comprising fungal isolate extract formulated in a growth medium for maintaining the viability of extract when the biological control composition is applied to weed. The present invention also discloses methods of screening fungal isolate to determine if they exhibit biocontrol activity. The present invention also discloses use of Setosphaeria monoceras strain. In yet a further aspect the invention relates to use of an Setosphaeria strain for producing a herbicidal agent effective for controlling growth of water hyacinth plants. The strain used preferably is a strain having the characterizing features of Setosphaeria strain AGWH#11 as deposited at IMTECH under accession number MTCC 5974.

Abstract: Disclosed herein are systems and methods for the creation, maintenance and management of virtual overlay networks across multiple communication networks managed by service providers. The simple creation and management of network overlays is accomplished via a network orchestrator manager, allowing for automation of configuration of connected network devices throughout an entire organization's network, regardless of the physical location of each device.

Abstract: The present disclosure relates to an integrated circuit, which includes a semiconductor substrate and an interconnect structure disposed over the semiconductor substrate. The interconnect structure includes a lower metal layer, an intermediate metal layer disposed over the lower metal layer, and an upper metal layer disposed over the intermediate metal layer. An upper surface of the lower metal layer and a lower surface of the intermediate metal layer are spaced vertically apart by a first distance. A resistive random access memory (RRAM) cell is arranged between the lower metal layer and the upper metal layer. The RRAM cell includes a bottom electrode and a top electrode which are separated by a data storage layer having a variable resistance. The data storage layer vertically spans a second distance that is greater than the first distance.

Abstract: A method can include applying a patterned mask over a semiconductor structure, the semiconductor structure having a dielectric layer, forming using the patterned mask a material formation trench intermediate first and second spaced apart metal formations formed in the dielectric layer, and disposing a dielectric material formation in the material formation trench.

Abstract: The present invention provides an improved method for the purification of monoclonal antibody from cell culture. Process of purification of the desired monoclonal antibody comprises affinity, hydrophobic interaction and optionally ion exchange column chromatography. It provides more than 99% purity of the desired monoclonal antibody.

Abstract: A field effect transistor having a channel that comprises three-dimensional graphene foam. The subject matter of the invention concerns a three dimensional field-effect transistor having a channel based on graphene foam and the use of ionic liquid as a gate. The graphene foam is made of a three-dimensional network of single and double layer graphene that extends in all the three dimensions. Metal contacts on either end of the graphene foam form the drain and source contacts of the transistor.

Abstract: Methodologies and a device for reducing capacitance and improving profile control are provided. Embodiments include forming metal vias in a first dielectric layer; forming a graded interlayer dielectric over the metal vias; forming a metal layer in the graded ILD over one of the metal vias; and forming a hydrogenated amorphous silicon carbon film over the metal layer.

Abstract: A sensor that can provide multiple resolutions, based on the output of the same analog-to-digital converter is disclosed. Some applications require a fast measurement of a physical parameter (e.g., temperature, voltage, pressure), but can tolerate a lower resolution measurement. Other applications require a higher resolution measurement, but can tolerate a slower measurement. The sensor may comprise a sigma delta modulator (SDM) ADC that outputs a digital reading. The output may comprise a bus having a width that is equal to the desired highest resolution of the digital code for the physical parameter. The sensor may further comprise a storage unit for each desired level of resolution. The sensor may further comprise logic that causes the storage units to sample the output bus after a certain number of clock cycles in order to store a digital code having a number of bits equal to the resolution.

Abstract: A method and system for determining fractional flow reserve (FFR) for a coronary artery stenosis of a patient is disclosed. In one embodiment, medical image data of the patient including the stenosis is received, a set of features for the stenosis is extracted from the medical image data of the patient, and an FFR value for the stenosis is determined based on the extracted set of features using a trained machine-learning based mapping. In another embodiment, a medical image of the patient including the stenosis of interest is received, image patches corresponding to the stenosis of interest and a coronary tree of the patient are detected, an FFR value for the stenosis of interest is determined using a trained deep neural network regressor applied directly to the detected image patches.

Abstract: A file stored in a first portion of a computer memory of a computer is determined to be a malicious file. A duplicate of the file is stored in a quarantine area in the computer memory, the quarantine area being in a second portion of the computer memory that is different from the first portion of the computer memory. One or more protection processes are performed on the file. The determination that the file is a malicious file is determined to be a false positive and the file is restored, during a boot sequence, to a state prior to the one or more protection processes being performed on the file.

Abstract: An apparatus for video summarization using sematic information is described herein. The apparatus includes a controller, a scoring mechanism, and a summarizer. The controller is to segment an incoming video stream into a plurality of activity segments, wherein each frame is associated with an activity. The scoring mechanism is to calculate a score for each frame of each activity, wherein the score is based on a plurality of objects in each frame. The summarizer is to summarize the activity segments based on the score for each frame.