Abstract: The present invention provides processes for the preparation of rivaroxaban and its intermediates.

Abstract: The present invention provides process for preparation of Crystalline Erlotinib HCl (I) Form-SE characterized by X-ray powder diffraction pattern comprising at least 5 characteristic 2?° peaks selected from the XRPD peak set of 5.60, 10.00, 11.40, 13.00, 13.50, 15.20, 18.40, 20.65, 21.86, 23.5, 31.80, 32.13, 32.80, 34.40±0.20 2?°, DSC isotherm comprising the endothermic peaks ranging between 213 to 217° C. (Peak -1) and 225 to 235° C. (Peak -2) and IR absorption characteristic peaks at approximately 3278 cm?1, 1948 cm?1, 1871 cm?1, 1632 cm?1, 1164 cm?1, 1024 cm?1, 940 cm?1 and 742 cm?1 useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment cancer.

Abstract: A method for compensating for panel capacitance the associated current is proposed, wherein the mutual capacitances of a capacitance sensing array are selectively coupled to drive voltages and to a self capacitance under test.

Abstract: The present invention relates to a process for the preparation of polymorphs of doripenem.

Abstract: A system and method for determination of importance of attributes among a plurality of attribute importance models incorporating a segmented attribute kerneling (SAK) method of attribute importance determination. The method permits operation of multiple attribute importance algorithms simultaneously, finds the intersecting subset of important attributes across the multiple techniques, and then outputs a consolidated ranked set. In addition, the method identifies and presents a ranked subset of the attributes excluded from the union.

Abstract: An external fixation system includes top and bottom fixation plates that may be connected to fragments of a bone. At least one y-shaped strut attaches the two fixation plates. Each y-shaped strut has first, second and third telescopic struts coupled at a connector joint. The first strut member is coupled to the top fixation plate and the second and third strut members are coupled to the bottom fixation plate. Each strut member may include a joint and may also include an actuation unit connecting the particular strut member to the top or bottom fixation plate. Rotation of a head portion of the actuation unit causes rotation of a threaded rod, causing adjustment in the length of the respective strut member. As the lengths of the strut members change, the joints may reposition, leading to the top fixation plate becoming repositioned with respect to the bottom fixation plate.

Abstract: A protocol identifies and configures rings in a network topology automatically in order to simplify and quicken the actions that need to be performed in response to addition, deletion and shuffle of network nodes in that topology. Such rings do not need to be identified and configured manually. The protocol involves two separate sequentially performed phases. In the first phase, the protocol can automatically identify all rings that are present within a Virtual Local Area Network (VLAN) topology. In the second phase, the protocol can automatically configure each node of each such ring in conformity with the Ethernet Ring Protection (ERP) protocol. After this ERP configuration has been performed, the failure of a link within the network will not require every network node to re-learn paths through the network; instead, the nodes that are required to re-learn such paths can be limited to those within the particular ring that contained the failed link.

Abstract: Methods of forming a polymeric nanocomposite are provided. The methods include combining one or more monomers to form a mixture and adding a plurality of carbon fibers to the mixture prior to or concurrently with formation of a polymer from the monomers. The methods can also include polymerizing the monomers to form the polymer and adding a hydrophobic agent and a plasticizer to the mixture to form the polymer nanocomposite.

Abstract: Interlayer fabrication methods and interlayer structure are provided having reduced dielectric constants. The methods include, for example: providing a first uncured insulating layer with an evaporable material; and disposing a second uncured insulating layer having porogens above the first uncured insulating layer. The interlayer structure includes both the first and second insulating layers, and the methods further include curing the interlayer structure, leaving air gaps in the first insulating layer, and pores in the second insulating layer, where the air gaps are larger than the pores, and where the air gaps and pores reduce the dielectric constant of the interlayer structure.

Abstract: A method implemented in a network apparatus used in a network is disclosed. The method comprises collecting information about network topology from a network controller, collecting information about data movement, deciding routing in the network according to the information about network topology and the information about data movement, and providing information about the routing to the network controller, wherein the network controller enforces the routing in the network. Other methods, apparatuses, and systems also are disclosed.

Abstract: The present invention provides Di potassium (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate (I) and its hydrates useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment of cancer. The present invention also provides process for preparation thereof.

Abstract: A method of determining at least one point of entry of smoke into a smoke detection system, the system having a sampling pipe network including at least one sampling pipe and a plurality of sampling inlets through which an air sample can enter the at least one sampling pipe of the smoke detection system for analysis by a particle detector, said method including: determining a volume of sample air that has passed through at least part of the smoke detection system since a predetermined event or a value corresponding to said volume; and determining through which sampling inlet of the plurality of sampling inlets the smoke entered the smoke detection system based, at least in part, on the determined volume or value. Systems for implementing such a method and related methods are also described.

Abstract: A system and method for optimized control of an assembly for drilling a borehole comprises a self-tuning, multivariable controller and an optimization engine that manipulates the setpoints of the controller such that drilling performance may be continuously optimized. The method includes evaluation of a characteristic system time constant, using this constant to compute bit ROP, using computed ROP to compute process gains, which are used to tune the multivariable controller, automatically refining controller setpoints based on controller performance, and using an optimization engine to systematically adjust controller setpoints such that drilling parameters are optimized based on any of several performance indicators, or a weighted combination of performance indicators.

Abstract: A method and system for anatomical object detection using marginal space deep neural networks is disclosed. The pose parameter space for an anatomical object is divided into a series of marginal search spaces with increasing dimensionality. A respective deep neural network is trained for each of the marginal search spaces, resulting in a series of trained deep neural networks. Each of the trained deep neural networks can evaluate hypotheses in a current parameter space using discriminative classification or a regression function. An anatomical object is detected in a medical image by sequentially applying the series of trained deep neural networks to the medical image.

Abstract: An external fixation frame for correcting a bone deformity includes a first fixation ring and a second fixation ring. A posterior adjustable length strut couples a posterior portion of the first fixation ring to a posterior portion of the second fixation ring and has universal joint. Medial and lateral adjustable length struts couples medial and lateral portions of the first fixation ring to medial and lateral portions of the second fixation ring respectively, each of the medial and lateral adjustable length struts including a constrained hinge joint. The fixation frame also includes a half ring hingedly coupled to the second fixation ring, and an anterior adjustable length strut coupling an anterior portion of the first fixation ring to the half ring.

Abstract: Methods and systems are described for cleaning contamination from the surface of an object within a lithographic apparatus. A lithographic apparatus is provided that includes an illumination system configured to condition a radiation beam, a support constructed to hold a patterning device (302), the patterning device being capable of imparting the radiation beam with a pattern in its cross-section to form a patterned radiation beam, a substrate table constructed to hold a substrate, and a projection system configured to project the patterned radiation beam onto a target portion of the substrate. The lithographic apparatus further includes a cleaning system (500) for cleaning particles off of a surface of either the support or the patterning device. The cleaning system includes a cleaning surface (502) designed to contact the surface of either the support or the patterning device.

Abstract: Provided is a process for the preparation of linagliptin of Formula I, comprising deprotecting a compound of Formula II wherein R1 and R2 together with the nitrogen to which they are attached form a phthalimido group, wherein the aromatic ring of the phthalimido group is substituted with one or more R3 substituents selected from the group consisting of halogen, alkyi, nitro and amino; or R1 is H and R2 is selected from the group consisting of trialkylsilyl, 2-trialkylsilylethoxycarbamates, acetyl, trihaloacetyl, 9-fluorenylmethoxycarbonyl, trityl, alkylsulfonyl, arylsulfonyl, diphenylphosphine and sulfonylethoxycarbonyl.

Abstract: Provided is a gesturing mechanism configured for facilitating interaction with a computer via a touchscreen device having a device surface. The mechanism includes a controller having a controller surface configured for accepting a touch gesture. The touchscreen device is configured for executing an application including a plurality of user controls for interacting with the application. The controller is configured for applying an accepted touch gesture to one of the plurality of controls.

Abstract: Object detection includes providing an image and determining at least one feature point. The at least one feature point defines a location of an image patch used for determining a feature descriptor, and the image patch defines an image area of the image. The feature descriptor is generated based on respective image intensities of a number of respective pairs of pixels with two dimensional coordinates located inside the image patch. An n-th component of the feature descriptor for an n-th pair of pixels is derived. A threshold is set depending on the number. The feature descriptor is generated by an arrangement of the M components. An indication signal is generated for a detected object when the feature descriptor is within a predefined distance to a reference feature descriptor.