Abstract: The present invention relates to ulmoside A as a novel small molecule adiponectin receptor agonist useful for prevention or cure of metabolic diseases. The present invention further relates to the use of ulmoside-A (ULMA) ((2S,3S)-(+)-3?,4?,5,7-tetrahydroxydihydroflavonol-6-C-?-D-glucopyranoside) for alleviation, management or prevention or treatment of steroid-induced metabolic disorder. The present invention further relates to a pharmaceutical composition useful for prevention and/or treatment of various medical indications associated with metabolic diseases caused in humans and animals.

Abstract: A method of reducing defects in and improving reliability of Back-End-Of-Line (BEOL) metal fill includes providing a starting metallization structure for semiconductor device(s), the metallization structure including a bottom layer of contact(s) surrounded by a dielectric material. The starting metallization structure further includes an etch-stop layer over the bottom layer, a layer of dielectric material over the etch-stop layer, a first layer of hard mask material over the dielectric layer, a layer of work function hard mask material over the first hard mask layer, a second layer of hard mask material over the work function hard mask layer, via(s) to the first hard mask layer and other via(s) into the etch-stop layer. The method further includes protecting the other via(s) while removing the second hard mask layer and the layer of work function hard mask material, and filling the vias with metal.

Abstract: An improved method for coupling carboxylic acids and amines is disclosed that includes the steps of combining a hyper-acid sensitive linker connecting an amine and a resin, a carboxylic acid, a carbodiimide, an activator additive, and a base, and carrying out the activation and coupling at a temperature greater than 30° C.

Abstract: A method and system for anatomical object detection using marginal space deep neural networks is disclosed. The pose parameter space for an anatomical object is divided into a series of marginal search spaces with increasing dimensionality. A respective sparse deep neural network is trained for each of the marginal search spaces, resulting in a series of trained sparse deep neural networks. Each of the trained sparse deep neural networks is trained by injecting sparsity into a deep neural network by removing filter weights of the deep neural network.

Abstract: The present invention discloses a process for depolymerization of lignin to yield substituted phenolic monomers using Brönsted ionic liquid as catalyst under mild reaction conditions to obtain an overall yield of monomers up to 97%.

Abstract: A method of setting a communicating session for executing an application includes determining an available bandwidth of each of a plurality of communicating sessions connected to a first device; determining a required bandwidth that is used to execute each of a plurality of applications that are executed on the first device; allocating at least one communicating session of the plurality of communicating sessions to at least one application of the plurality of applications, based on strengths of the respective available bandwidths of the plurality of communicating sessions and strengths of the respective required bandwidths of the plurality of applications; and executing the at least one application using the allocated at least one communicating session.

Abstract: A method and system for determining and improving the engagement between a customer and a company offering products and/or services is disclosed. As part of the process, a customer engagement score (“CES”) is calculated. The CES is a composite number that is used to measure how engaged and loyal a company's customers are. Each customer has their unique CES based on activity, relationship, usage of company product and services, rewards and their emotional and rational engagement with the company. Based on the CES, at least one recommended action to improve customer engagement is provided.

Abstract: Methods are provided for fabricating an interlayer structure useful in, for instance, providing BEOL interconnect for circuit structures. The method includes, for instance, providing an interlayer structure, including: providing an uncured insulating layer above a substrate structure; forming an energy removal film over the uncured insulated layer; forming at least one opening through the energy removal film and extending at least partially into the uncured insulating layer; and applying energy to cure the uncured insulating layer, establishing a cured insulating layer, and decomposing in part the energy removal film, establishing a reduced thickness, energy removal film over the cured insulating layer, the interlayer structure including the cured insulating layer, and the applying energy decreasing an aspect ratio(s) of the one opening(s). In one implementation, the uncured insulating layer includes porogens which also decompose partially during applying energy to further improve the aspect ratio(s).

Abstract: An external fixation system and method for realigning, compressing or distracting broken bones has a planar ring element with an adjustable device having a body releasably mounted on the ring element. The adjustable device includes a first member for movement in a direction generally perpendicular to the ring element. A second member is mounted on the first member for movement in a direction parallel to the first member and with respect to a circumference of the planar ring element. The method includes inserting a k-wire through a first piece of bone and affixing the k-wire to the ring element. Then inserting a second k-wire through a second piece of bone and affixing the k-wire to the adjustable device second member. The pieces of bone are realigned, compressed or distracted by adjusting at least one of a first and second adjustable members forming the device.

Abstract: Provided is a process for the preparation of linagliptin of Formula I, comprising deprotecting a compound of Formula II wherein R1 and R2 together with the nitrogen to which they are attached form a phthalimido group, wherein the aromatic ring of the phthalimido group is substituted with one or more R3 substituents selected from the group consisting of halogen, alkyi, nitro and amino; or R1 is H and R2 is selected from the group consisting of trialkylsilyl, 2-trialkylsilylethoxycarbamates, acetyl, trihaloacetyl, 9-fluorenylmethoxycarbonyl, trityl, alkylsulfonyl, arylsulfonyl, diphenylphosphine and sulfonylethoxycarbonyl.

Abstract: Techniques for reducing the latency in performing a failover from a protected connection to its backup connection when a network event is detected affecting the protected connection. In an MPLS network, techniques are provided for failing a protected LSP to a backup LSP in a fast and efficient manner. In one embodiment, the faster failover is facilitated by storing protected LSPs and their backup LSPs information in the data plane, such as locally on a linecard.

Abstract: A method includes storing a plurality of workloads in a first disk resource associated with a high end disk classification. The method further includes determining a corresponding activity level for each of the plurality of workloads. The method also includes classifying each of the plurality of workloads into a first set indicative of high-priority workloads and a second set indicative of low-priority workloads based on whether the corresponding activity level is greater than a threshold activity level. The method further includes determining whether a second disk resource associated with a low end disk classification can accommodate storage of a first particular workload in the second set based on an available storage capacity of the second disk resource. The method additionally includes migrating the first particular workload from the first disk resource to the second disk resource.

Abstract: Methods, systems, and devices are described for wired communication. In one aspect, a method includes selecting a gain scalar based at least in part on a constellation point distance associated with a constellation mapper for a line and a tone. The method also includes applying the gain scalar to a tone data output signal of a vector processor.

Abstract: Systems and methods are disclosed herein that relate to automated measurement and analysis of end-to-end performance of Voice over Long Term Evolution (VoLTE) service and, in some embodiments, automated network optimization for VoLTE service performance improvement. In some embodiments, a method of operation of a network node to perform automated end-to-end analysis of VoLTE sessions is provided. In some embodiments, the method of operation of the network node comprises correlating control and data plane messages across a nodes and interfaces in a VoLTE network to thereby provide data representative of end-to-end message flows for a plurality of VoLTE sessions. The method of operation further comprises configuring one or more nodes in the VoLTE network based on the data representative of the end-to-end message flows for the plurality of VoLTE sessions. In this manner, automated network optimization for VoLTE service performance improvement can be provided.

Abstract: A computer implemented method for determining a cost of a casting process includes receiving a user input, via a Graphical User Interface (GUI), indicative of part information that is associated with a part manufactured by the casting process. The method includes receiving a user input, via the GUI, to select a casting parameter associated with the casting process. The casting parameter includes material and post-treatment parameter, mold and core parameter, foundry process parameter, and machining and setup parameter. The method includes receiving a user input, via the GUI, indicative of a variable associated with the casting parameter and retrieving a cost information associated with the casting parameter from a database. The method further includes determining a parameter cost based on the cost information and the variable and, generating an output, via the GUI, indicative of the cost of the casting process for the part.

Abstract: An electronic device includes a power supply, a ground, and an intermediate ground having a voltage less than a voltage of the power supply and greater than a voltage of the ground. The electronic device also includes an error amplifier having an input stage coupled between the power supply and the ground, and an output stage coupled between the power supply and the intermediate ground. A ballast transistor is coupled to receive an output from the error amplifier. A feedback circuit is coupled to an output of the ballast transistor to generate feedback signals, and the error amplifier operates in response to the feedback signals.

Abstract: A network access system, e.g. a network hotspot, requires a mobile network access device, e.g. a smart phone or WiFi only device, to provide a network access standard designation and/or a device identification datum to gain access to network services. The network access standard designation may be provided by the mobile network access device to an online signup server via a EKU_key_purpose field of a PKCS10 certificate signing request. The device identification datum may be provided to the OSU via a subject field of the signing request. The OSU may require that the device identification datum be the same as a device identification datum provided by the mobile network access device prior to the mobile network access device requesting a signed network access certificate.

Abstract: A protocol identifies and configures rings in a network topology automatically in order to simplify and quicken the actions that need to be performed in response to addition, deletion and shuffle of network nodes in that topology. Such rings do not need to be identified and configured manually. The protocol involves two separate sequentially performed phases. In the first phase, the protocol can automatically identify all rings that are present within a Virtual Local Area Network (VLAN) topology. In the second phase, the protocol can automatically configure each node of each such ring in conformity with the Ethernet Ring Protection (ERP) protocol. After this ERP configuration has been performed, the failure of a link within the network will not require every network node to re-learn paths through the network; instead, the nodes that are required to re-learn such paths can be limited to those within the particular ring that contained the failed link.