Abstract: Systems and methods include reception of an indication of a first data object to transmit from a first database tenant to a second database tenant, the first data object comprising user configuration settings metadata of a database application and associated with a first data object type, determination of whether a dependent data object may be associated with a data object of the first data object type, determination, if it is determined that a dependent data object may be associated with a data object of the first data object type, of whether a dependent object is dependent on the first data object, and automatic determination, if it is determined that a dependent object is dependent on the first data object, to transmit the dependent object from the first database tenant to the second database tenant.

Abstract: Some embodiments provide a method for associating data message flows from applications executing on a host computer with network interfaces of the computer. The method of some embodiments identifies a set of applications operating on a machine executing on the host computer, identifies candidate teaming policies for associating each identified application with a subset of one or more interfaces, and generates a report to display the identified candidate teaming policies per application to a user. In response to user input selecting a first teaming policy for a first application, the method generates a rule, and distributes the rule, to the host computer to associate the first application with a first subset of the network interfaces specified by the first teaming policy.

Abstract: There are provided systems and methods for a fallback artificial intelligence (AI) system for redundancy during system failover. A service provider may provide AI systems for automated decision-making, such as for risk analysis, marketing, and the like. An AI system may operate in a production computing environment in order to provide AI decision-making based on input data, for example, by providing an output decision. In order to provide redundancy to the production AI system, the service provider may train a fallback AI system using the input/output data pairs from the production AI system. This may utilize a deep neural network and a continual learning trainer. Thereafter, when a failover condition is detected for the production AI system, the service provider may switch from the production AI system to the fallback AI system, which may provide decision-making operations during failure of within the production computing environment.

Abstract: Biologically-inspired compositions, including color changing compositions, and corresponding embodiments such as sensors, textile materials, coatings and films, are provided which typically include a solid, transparent and nondegradable matrix. The matrix contains a plurality of (i) synthetic particles having a size in the micrometer or nanometer range, each synthetic particle including one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45, the aggregates having a size larger than about 100 nm; or (ii) submicrometer natural particles extracted and purified from homogenized tissue.

Abstract: In one aspect, a method performed by a network node for predicting a probability of state change of a node (e.g., a fog node) in a network is provided. The network node determines a set of weights based on attributes of the node. The network node estimates the probability of state change of the node using the determined set of weights and a set of one or more attribute values related to the node where determining the set of weights includes maximizing an evaluation value associated to the node.

Abstract: Techniques for creating a user network based on user interest in a product are described. For example, a first search query is received from a first client device. The first client device is associated with a first user. A second search query is received from a second client device. The second client device is associated with a second user. The first search query is matched to a product. The second search query is matched to the product. A user network corresponding to the product is created. The first user is added to the user network based on the matching of the first search query to the product. The second user is added to the user network based on the matching of the second search query to the product.

Abstract: Rotorcraft lighting equipment includes a plurality of lighting devices configured to be mounted to an exterior of a rotorcraft, wherein each of the lighting devices comprises a plurality of individually controllable lighting modules which are configured for emitting light into different spatial directions; and a lighting control device configured for individually controlling the operation of the plurality of lighting modules for generating a desired light distribution of the light emitted by the plurality of lighting modules.

Abstract: Medicaments for use in treating T-cell acute lymphoblastic leukemia, acute lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, breast cancer, ovarian cancer, melanoma, lung cancer, pancreatic cancer, glioblastoma, sarcoma, desmoid tumors, adenoid cystic carcinoma, colorectal cancer, head and neck cancer, cervical cancer, prostate cancer, liver cancer, or skin cancer in a patient comprising combination therapy with 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]butanamide, or a pharmaceutically acceptable salt or hydrate thereof, and 8-[5-(1-hydroxy-1-methylethyl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one, or a pharmaceutically acceptable salt thereof.

Abstract: A method and system for a content broker, including a unified object index, where the content broker is coupled to the unified object index and receives, from a requesting entity, a request to perform an action on an object and the object is stored in the content repository. The method further including obtaining the object associated with the request from a content repository, determining, using the unified object index, a normalized object type associated with the object, obtaining a governance rule based on the normalized object type, and servicing the request using the governance rule.

Abstract: Pharmaceutical formulation comprising centanafadine or a pharmaceutically acceptable salt thereof and an excipient, and related methods of manufacture and use, are disclosed.

Abstract: Technologies for providing deduplication of data in an edge network includes a compute device having circuitry to obtain a request to write a data set. The circuitry is also to apply, to the data set, an approximation function to produce an approximated data set. Additionally, the circuitry is to determine whether the approximated data set is already present in a shared memory and write, to a translation table and in response to a determination that the approximated data set is already present in the shared memory, an association between a local memory address and a location, in the shared memory, where the approximated data set is already present. Additionally, the circuitry is to increase a reference count associated with the location in the shared memory.

Abstract: Certain aspects of the present disclosure provide techniques for wound management and treatment. This includes determining characteristics of a wound for a patient based on an image of the wound, including detecting the characteristics based on analyzing the image using a first ML model trained to detect wound characteristics from a captured image. The techniques further include identifying patient medical data including characteristics relating to a medical history for the patient, and predicting a first care plan for the patient based on providing the characteristics of the wound and the patient medical data to a second ML model. The second ML model is trained to predict the first care plan using prior wound care outcome data including a prior wound care outcomes relating to prior patients. The first care plan is configured to be used to treat the wound for the patient.

Abstract: The present disclosure is directed to inhibitors of Formula (0), or a stereoisomer thereof, or pharmaceutically acceptable salt thereof, of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: The present invention relates to a method for diagnosing Sézary syndrome or mycosis fungoides in a subject. The present invention further relates to a method for determining the frequency of Sézary signature cells and/or mycosis fungoides cells in a sample. Further, the present invention relates to a computer-implemented method comprising a classifier algorithm to determine the frequency of Sézary signature cells and/or mycosis fungoides cells. In addition the present invention relates to a panel of biomarkers that can be used for the diagnosis of Sézary syndrome or mycosis fungoides.

Abstract: In one embodiment, an apparatus couples to a host processor over a Compute Express Link (CXL)-based link. The apparatus includes a transaction queue to queue memory transactions to be completed in an addressable memory coupled to the apparatus, a transaction cache, conflict detection circuitry to determine whether a conflict exists between memory transactions, and transaction execution circuitry. The transaction execution circuitry may access a transaction from the transaction queue, the transaction to implement one or more memory operations in the memory, store data from the memory to be accessed by the transaction operations in the transaction cache, execute operations of the transaction, including modifying data from the memory location stored in the transaction cache, and based on completion of the transaction, cause the modified data from the transaction cache to be stored in the memory.

Abstract: In one embodiment, a device obtains path metrics for a network path used to convey application traffic for an online application. The device discretizes the path metrics into labeled states. The device generates state transition visualization data that represents the labeled states as nodes and transitions between the labeled states as edges connecting the nodes. The device provides the state transition visualization data for display.

Abstract: The present invention relates to bispecific compound of formula (I) as dual inhibitors of CD73 and adenosine receptors. The present invention also relates to pharmaceutical compositions comprising said compounds or a pharmaceutically acceptable salt or a stereoisomer or a prodrug thereof and use of such compounds in the treatment of diseases mediated by CD73 and/or adenosine receptors, particularly A2aR or A2bR.

Abstract: Real-time dynamic optimization of a process model in an online model-based process control computing environment. A mixed integer nonlinear programming (MINLP) solver utilizes a switch to activate and deactivate a first-principle model of a process unit. The switch enables MINLP behavior by attaching to the first-principle model.

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.

Abstract: The present invention relates to a film-coated swallowable tablet comprising eltrombopag bis(monoethanolamine) and pharmaceutically acceptable excipients comprising maltose and isomalt as diluents. The invention further relates to the use of said tablet as a medicament, particularly in the treatment of immune thrombocytopenia (ITP), thrombocytopenia inpatients with chronic hepatitis C virus (HCV) and severe aplastic anaemia (SAA).