Abstract: The present disclosure relates to a mobile terminal, which is adopted to improve the accuracy of detecting ambient light. The mobile terminal includes a display panel, a first phase retarder, a light splitting element, and at least one light sensor. The first phase retarder is located between the display panel and the light splitting element; and the at least one light sensor is arranged opposite to the light splitting element, and to receive ambient light and light emitted by the display panel. The ambient light passing through the display panel and the light emitted by the display panel sequentially pass through the first phase retarder and the light splitting element. According to the technical solution of the present disclosure, the accuracy of detecting ambient light may be improved.

Abstract: A PDL1 block CAR-T transgenic vector for suppressing immune escape includes: AmpR sequence containing ampicillin resistance gene (SEQ ID NO: 1); prokaryotic replicon pUC Ori sequence (SEQ ID NO: 2); virus replicon SV40 Ori sequence (SEQ ID NO: 3); eWPRE enhanced posttranscriptional regulatory element of hepatitis B virus (SEQ ID NO: 11); human EF1a promoter (SEQ ID NO: 12); lentiviral packaging cis-elements for lentiviral packaging; humanized single-chain antibody fragment PDL1scFv1 (SEQ ID NO: 21), PDL1scFv2 (SEQ ID NO: 22), or PDL1scFv3 (SEQ ID NO: 23) of human PDL1; IRES ribosome binding sequence (SEQ ID NO: 25); IL6 signal peptide (SEQ ID NO: 26); human antibody Fc segment (SEQ ID NO: 27); and chimeric antigen receptors of the second or third generation CAR for integrating recognition, transmission and initiation. A preparation method of the PDL1 block CAR-T transgenic vector and an application thereof in a preparation of anti-immune escape drugs.

Abstract: A semiconductor device includes a transistor, a semiconductor layer, an active region and a conductive layer. The active region is in the semiconductor layer. The conductive layer is configured to maintain a channel in the active region when the transistor is triggered to be conducted.

Abstract: Provided are a siRNA of the human interleukin 6, a recombinant expression CAR-T vector, and a construction method and a use thereof. The siRNA can be used in the treatment of acute B-cell lymphocytic leukemia with CAR19-T for eliminating or alleviating the symptoms of cytokine release syndrome (CRS), and can also be used for alleviating the CRS symptoms caused by treating tumours with CAR-T and even can also be used for alleviating CRS caused by other types of treatment.

Abstract: An electronic device may have a housing with a display. A transparent portion of the housing may serve as a display cover layer and may overlap an array of pixels in the display. The array of pixels may form an active area of the display for displaying images for a user. An ambient light sensor window may be formed in an inactive area of the display that does not overlap pixels. An ambient light sensor may be mounted in an interior region of the housing. A metal-coated light guide may have a first end aligned with the ambient light sensor window to receive ambient light from an exterior region surrounding the device and may have a second end at which the ambient light is provided to the ambient light sensor.

Abstract: A wagon and a car body assembly thereof are provided. The car body assembly includes at least two bogies, an underframe and a car body both supported on the two bogies, the car body includes a middle car body, and a discharge opening of the middle car body is arranged between the two bogies, and at least one end of the middle car body is further provided with an end car body, and a predetermined space is defined above the respective bogie by adjacent end walls of the middle car body and the end car body.

Abstract: An OCTS-based CAR-T vector for treating malignant glioma includes lentiviral skeleton plasmid, human EF1? promoter (SEQ ID NO.14), OCTS chimeric receptor structural domain, and PDL1 single-chain antibody; the OCTS chimeric receptor structural domain consists of CD8 leader chimeric receptor signal peptide (SEQ ID NO.15), PDL1 single-chain antibody light chain VL (SEQ ID NO.16), PDL1 single-chain antibody heavy chain VH (SEQ ID NO.17), EGFRvIII single-chain antibody light chain VL (SEQ ID NO.18), EGFRvIII single-chain antibody heavy chain VH (SEQ ID NO.19), antibody Inner-Linker (SEQ ID NO.20), single-chain antibody Inter-Linker (SEQ ID NO.21), CD8 Hinge chimeric receptor linker (SEQ ID NO.22), CD8 Transmembrane chimeric receptor transmembrane domain (SEQ ID NO.23), TCR chimeric receptor T cell activation domain (SEQ ID NO.26) and chimeric receptor co-stimulator domain.

Abstract: An OCTS-based CAR-T vector for treating pancreatic cancer and malignant mesothelioma includes lentiviral skeleton plasmid, human EF1? promoter (SEQ ID NO.14), OCTS chimeric receptor structural domain, and PDL1 single-chain antibody; the OCTS chimeric receptor structural domain consists of CD8 leader chimeric receptor signal peptide (SEQ ID NO.15), PDL1 single-chain antibody light chain VL (SEQ ID NO.16), PDL1 single-chain antibody heavy chain VH (SEQ ID NO.17), MESOTHELIN single-chain antibody light chain VL (SEQ ID NO.18), MESOTHELIN single-chain antibody heavy chain VH (SEQ ID NO.19), antibody Inner-Linker (SEQ ID NO.20), single-chain antibody Inter-Linker (SEQ ID NO.21), CD8 Hinge chimeric receptor linker (SEQ ID NO.22), CD8 Transmembrane chimeric receptor transmembrane domain (SEQ ID NO.23), TCR chimeric receptor T cell activation domain (SEQ ID NO.26) and chimeric receptor co-stimulator domain.

Abstract: The disclosure provides an N-type thin film transistor, including a poly-silicon layer, a gate layer, a source and a drain. The poly-silicon layer includes a channel region, a source region and a drain region at two side of the channel region. The gate layer is on the channel region, a projection of the gate layer on the poly-silicon layer partially overlaps the source region and the drain region, and a thickness of the gate layer on the source region and the drain region are smaller than a thickness of the gate layer on the channel region. The source region and the drain region both include a heavily-doping region and a lightly-doping region connected to the heavily-doping region, the source and the drain are respectively on the heavily-doping region of the source region and the drain, and respectively electrically connects to the heavily-doping region of the source region and the drain.

Abstract: A drive circuit for driving a display panel includes a dynamic refresh unit, a timer, and a black insertion drive unit. The dynamic refresh unit is configured to output a dynamic refresh signal, so as to control the display panel to display a plurality of frames in sequence. A frame time of each of the frames is adjusted according to the dynamic refresh signal. The timer is configured to compute a black insertion time signal. The black insertion drive unit is configured to output a black insertion drive signal according to the black insertion time signal, so as to perform black insertion on the frames.

Abstract: A flexible AMOLED substrate and a manufacturing method thereof are provided. The method includes: forming a flexible backing, which includes a display section and a bending section disposed on an outer circumference of the display section; forming a buffer layer on the flexible backing, removing a portion of the buffer layer that is disposed on the bending section and preserving a portion of the buffer layer that is disposed on the display section so that an inorganic insulation layer on the bending section has a reduced thickness to improve bending resistance of the bending section of the flexible AMOLED substrate and thus improving production yield. The flexible AMOLED substrate is manufactured with the above method, in which an inorganic insulation layer included in a bending section has a reduced thickness so that the bending section of the flexible AMOLED substrate shows better resistance against bending and provides high production yield.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating a target sequence from an input sequence. In one aspect, a method comprises maintaining a set of current hypotheses, wherein each current hypothesis comprises an input prefix and an output prefix. For each possible combination of input and output prefix length, the method extends any current hypothesis that could reach the possible combination to generate respective extended hypotheses for each such current hypothesis; determines a respective direct score for each extended hypothesis using a direct model; determines a first number of highest-scoring hypotheses according to the direct scores; rescores the first number of highest-scoring hypotheses using a noisy channel model to generate a reduced number of hypotheses; and adds the reduced number of hypotheses to the set of current hypotheses.

Abstract: A coherent photon analog-to-digital conversion device comprising an optical clock oscillation source, a sampled signal source, a photon sampling gate, a photoelectric detection module, an electrical sampling module, a phase detection module, a loop filter, and signal feedback links. By adjusting the optical clock oscillating source or the sampled signal source, the invention makes the two highly coherent, thereby reducing the clock jitter and greatly improving the sampling precision. It is very important for improving the performance of microwave photon systems that require high time accuracy and high sampling accuracy, such as microwave photon radar and optical communication systems.

Abstract: The present disclosure provides a semiconductor device comprising a substrate; a first III-V compound layer over the substrate; a second III-V compound layer on the first III-V compound layer; a third III-V compound layer on the second III-V compound layer; a source region on the third III-V compound layer; a drain region on the third III-V compound layer; a first dielectric layer arranged on the second III-V compound layer through the third III-V compound layer; and a gate region on the first dielectric layer, wherein a bottom of the gate region is higher than a top surface of the first dielectric layer; the second lateral distance is larger than the first lateral distance.

Abstract: A connector surfaces a configuration user experience that allows a user to select notifications that a user wishes to receive from a service. The user's e-mail system has a URL endpoint identifier, and the service sends the selected notifications to the URL endpoint. The notifications are integrated into the user's inbox, as e-mail messages.

Abstract: The description is directed to ionizable lipids useful for enhancing the delivery of therapeutic agents in liposomes.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating a target sequence from an input sequence. In one aspect, a method comprises maintaining a set of current hypotheses, wherein each current hypothesis comprises an input prefix and an output prefix. For each possible combination of input and output prefix length, the method extends any current hypothesis that could reach the possible combination to generate respective extended hypotheses for each such current hypothesis; determines a respective direct score for each extended hypothesis using a direct model; determines a first number of highest-scoring hypotheses according to the direct scores; rescores the first number of highest-scoring hypotheses using a noisy channel model to generate a reduced number of hypotheses; and adds the reduced number of hypotheses to the set of current hypotheses.

Abstract: The present disclosure relates to an automatic unloading carrier and an unmanned aerial vehicle. The automatic unloading carrier includes: a mounting base for being fixed with an unmanned carrying vehicle, a carrying arm driving mechanism and multiple carrying arms connected with the mounting base through the carrying arm driving mechanism, the multiple carrying arms are configured to be unfolded or folded due to the driving of the carrying arm driving mechanism, and the multiple carrying arms are configured to form a space for carrying a carried object during a folded state and release the carried object during an unfolded state.

Abstract: Disclosed are a method and a device for controlling flow of liquid zinc (2) in a zinc pot (1) for hot-dip galvanization. Under the blowing effects of an air knife above the zinc pot (1) for hot-dip galvanization onto strip steel (3), the liquid zinc (2) diffuses and flows outwards to zones (zones I, II, III and IV) comprising the left side, the right side, the front end of the zinc pot, respectively, and a zone between the strip steel (3) and a furnace snout (4), and surface dross rapidly generated on the surface of the liquid zinc (2) is driven to flow outwards to the zones (zones I, II, III and IV). On edge sides of the zones (zones I, II, III and IV), travelling magnetic field generators (71, 72, 73, 74, 75, 76, 77, 78, 712, 756) are arranged in multiple sections above the surface of the liquid zinc (2) in the zinc pot (1), so as to excite a travelling magnetic field to generate an electromagnetic driving force on the liquid zinc (2) to drive the flow of the liquid zinc (2).