Patents by Inventor Liang Chang

Liang Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230310401
    Abstract: Disclosed is a pharmaceutical composition containing dabigatran etexilate and a preparation method thereof. The pharmaceutical composition comprises a pharmaceutically active ingredient, dabigatran etexilate and/or dabigatran etexilate mesylate, an amphiphilic polymer of polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer, and a hydrophilic polymer of polyoxyethylene-polyoxypropylene glycol block copolymer. The mass percentage of the active pharmaceutical ingredient in the pharmaceutical composition is 5 wt % to 60 wt %; the mass percentage of the amphiphilic polymer in the pharmaceutical composition is 3 wt % to 40 wt %; and the mass percentage of the hydrophilic polymer in the pharmaceutical composition is 10 wt % to 90 wt %. The pharmaceutical composition not only increases the bioavailability of the pharmaceutically active ingredient, but also reduces absorption variability, and provides a more stable concentration of dabigatran in plasma, thereby reducing adverse side effects.
    Type: Application
    Filed: June 9, 2023
    Publication date: October 5, 2023
    Inventors: Liang Chang DONG, Shizhong ZHANG, Yan JIAO, Danyong ZHANG, Wenfang ZHAO, Jingmin SHI
  • Patent number: 11771690
    Abstract: A solid particle, a preparation method therefor, and a pharmaceutical composition. The solid particle comprises a porous solid particle and a non-aqueous liquid formula. The non-aqueous liquid formula comprises 0.10-4.00 wt % of a hydrophobic active pharmaceutical agent, 28.00-99.90 wt % of a hydrophobic solubilizing solution, 0-70.00 wt % of a non-ionic surfactant, and 0-1.00 wt % of an antioxidant. The hydrophobic solubilizing solution comprises a medium-chain monoglyceride and diglyceride, and/or a propylene glycol fatty acid monoester.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: October 3, 2023
    Assignee: SHANGHAI WD PHARMACEUTICAL CO., LTD
    Inventors: Liang Chang Dong, Wenbo Ma, Lin Wang
  • Patent number: 11759417
    Abstract: Disclosed are a pharmaceutical composition, an osmotic pump controlled-release drug delivery system comprising the pharmaceutical composition and a preparation method therefor. The pharmaceutical composition comprises a tablet core and a coating film. The tablet core comprises a drug-pulling layer, and the coating film comprises 50-90 wt % of cellulose acetate and 10-50 wt % of Copovidone. The Copovidone can be obtained by means of the polymerization of vinyl pyrrolidone and vinyl acetate in a molar ratio of 40:60-80:20.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: September 19, 2023
    Assignee: SHANGHAI WD PHARMACEUTICAL CO., LTD
    Inventors: Liang Chang Dong, Xishan Chen
  • Publication number: 20230289316
    Abstract: A method of transmitting data and command through an RS232 serial port incorporated with a user-end device and a server-end device connected through the RS232 serial port is disclosed and includes following steps: accumulating a value of a first counter of the user-end device and a value of a second counter of the server-end device whenever a data is transmitted from the server-end device to the user-end device; controlling the server-end device to stop transmitting the data and to wait when both of the two values reach a triggering threshold; controlling the user-end device to transmit a control command to the server-end device through the RS232 serial port while the server-end device is waiting; and, resetting the first and the second counter and controlling the server-end device to restore to transmit the data to the user-end device after a waiting time is elapsed.
    Type: Application
    Filed: June 22, 2022
    Publication date: September 14, 2023
    Inventor: Yung-Liang CHANG
  • Patent number: 11749176
    Abstract: An electronic apparatus includes a housing, a first light emitting array and a second light emitting array. The first light emitting array includes first light-emitting units disposed in a first left region and a second left region. The second light emitting array is disposed adjacent to the first light emitting array. The second light emitting array includes second light-emitting units disposed in a first right region and a second right region. The difference between the average brightness in the first left region and the average brightness in the first right region is in a range from 0% to 20%, and the difference between the average brightness in the second left region and the average brightness in the second right region is less than the difference between the average brightness in the first left region and the average brightness in the first right region.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: September 5, 2023
    Assignee: INNOLUX CORPORATION
    Inventors: Chi-Liang Chang, Yi-Hua Hsu
  • Publication number: 20230270324
    Abstract: A method of imaging tissue of a subject using an electronic rolling shutter imager includes sequentially resetting rows of pixels of the rolling shutter imager from a first row to a last row for a first amount of time; illuminating the tissue of the subject with illumination light over an illumination period that begins once the last row of the rolling shutter imager has been reset and lasts for at least the first amount of time; accumulating charge at the rows of pixels over at least the illumination period based on light that is received from the tissue of the subject while the tissue of the subject is illuminated with the illumination light; sequentially reading charge accumulated at the rows of pixels from the first row to the last row once the illumination period has ended; and generating an image frame from the rows of pixels.
    Type: Application
    Filed: May 1, 2023
    Publication date: August 31, 2023
    Applicant: Stryker Corporation
    Inventors: William Huei Liang CHANG, Bryan LARSON, John SHEN, Benjamin FEINGOLD, Ajay RAMESH
  • Publication number: 20230233613
    Abstract: The present invention provides a pharmaceutical composition for treating chronic stroke, involving injection via brain into the cranium of a patient having chronic stroke for six months or more; the pharmaceutical composition is a suspension at least comprising TS stem cells, an active synergistic component and a growth factor, wherein the expression level of CD34 and CD45 of the TS stem cells is 10% or less, and the expression level of CD90 and CD105 is 90% or more; the active synergistic component is an extracellular vesicle; the growth factor is at least one selected from the group consisting of HGF, G-CSF, Fractalkine, IP-10, EGF, IL-1?, IL-1?, IL-4, IL-5, IL-13, IFN?, TGF? and sCD40L. The present invention overcomes the limitations of previous cell therapy and provides a cell-based preparation that is clinically safe and therapeutically effective for chronic cerebral stroke.
    Type: Application
    Filed: October 11, 2022
    Publication date: July 27, 2023
    Inventors: Po-Cheng Lin, Pi-Chun Huang, Chia-Hsin Lee, Ming-Hsi Chuang, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang, Yi-Chun Lin, Yu-Chen Tsai, Peggy Leh Jiunn Wong, Ruei-Yue Liang
  • Patent number: 11707455
    Abstract: Disclosed is a pharmaceutical composition containing dabigatran etexilate and a preparation method thereof. The pharmaceutical composition comprises a pharmaceutically active ingredient, dabigatran etexilate and/or dabigatran etexilate mesylate, and a amphiphilic polymer of polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer. The mass ratio of the two is 1:0.23 to 1:3. The pharmaceutical composition not only increases the bioavailability of the pharmaceutically active ingredient, but also reduces absorption variability, and provides a more stable concentration of dabigatran in plasma, thereby reducing adverse side effects.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: July 25, 2023
    Assignee: SHANGHAI WD PHARMACEUTICAL CO., LTD
    Inventors: Liang Chang Dong, Shizhong Zhang, Yan Jiao, Danyong Zhang, Wenfang Zhao, Jingmin Shi
  • Publication number: 20230208209
    Abstract: A magnetic attraction structure for a wireless charging device or a terminal device is provided, which includes one or more electromagnets. The electromagnet includes an iron core and a winding group. The iron core includes a first plate, a second plate and a connecting part. The first plate is separated from the second plate by a distance, and the connecting part is connected between the first plate and the second plate, and the winding group surrounds the connecting part. A side surface of a long side of the first plate and a side surface of a long side of the second plate are configured to face a cover plate of the wireless charging device or a cover plate of the terminal device. A wireless charging device including the above-mentioned magnetic attraction structure is also provided.
    Type: Application
    Filed: January 14, 2022
    Publication date: June 29, 2023
    Inventor: Xin-Liang Chang
  • Publication number: 20230179545
    Abstract: A packet forwarding apparatus includes a first storage device and a processor. The first storage device has a plurality of buffers allocated therein, and at least one buffer included in the plurality of buffers is arranged to buffer at least one packet. The processor is arranged to execute a Linux kernel to perform software-based packet forwarding associated with the at least one packet. The at least one buffer allocated in the first storage device is recycled through direct memory access (DMA) management, and is reused for buffering at least one other packet.
    Type: Application
    Filed: July 25, 2022
    Publication date: June 8, 2023
    Applicant: MEDIATEK INC.
    Inventors: Ching-Liang Chang, Wei-Lun Liu
  • Publication number: 20230143737
    Abstract: The present application discloses a thermal insulation coating and a method for applying the same. Raw materials for preparing the thermal insulation coating includes PVDF resin, water-based epoxy resin solution, hollow glass microbead, ytterbium modified nano-powder, diluent, polyvinyl alcohol, titanium dioxide powder, rare earth, negative ion powder, and leveling agent.
    Type: Application
    Filed: November 28, 2022
    Publication date: May 11, 2023
    Inventors: Zhenlu MIAO, Minhua MO, Changming LI, Dongqin QIU, Liang CHANG
  • Patent number: 11638517
    Abstract: A method of imaging tissue of a subject using an electronic rolling shutter imager includes sequentially resetting rows of pixels of the rolling shutter imager from a first row to a last row, sequentially reading charge accumulated at the rows of pixels from the first row to the last row, wherein the first row is read after resetting the last row, illuminating the tissue of the subject with illumination light for an illumination period that lasts longer than a vertical blanking period, wherein the vertical blanking period is the period from the resetting of the last row to the reading of the first row, and generating an image frame from the readings of charge accumulated at the rows of pixels, wherein at least one reading of charge accumulated at a row of pixels is removed or replaced to generate the image frame.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: May 2, 2023
    Assignee: Stryker Corporation
    Inventors: William Huei Liang Chang, Bryan Larson, John Shen, Benjamin Feingold, Ajay Ramesh
  • Publication number: 20230102366
    Abstract: An electronic device is disclosed and includes a substrate, a circuit layer, and a plurality of diodes. The substrate has a plurality of structures. The circuit layer is disposed on the substrate. The diodes are disposed on the circuit layer, wherein a first spacing is defined as a distance between a center point of a first one of the structures and a center point of a second one of the structures, a second spacing is defined as a distance between a center point of a third one of the structures and a center point of a fourth one of the structures, and an absolute value of a difference between the first spacing and the second spacing is less than 0.5 times radius of curvature of the electronic device when the electronic device is bent.
    Type: Application
    Filed: December 6, 2022
    Publication date: March 30, 2023
    Applicant: InnoLux Corporation
    Inventors: Chin-Lung Ting, Chung-Kuang Wei, Li-Wei Mao, Chi-Liang Chang, Chia-Hui Lin
  • Patent number: 11598549
    Abstract: A heat cycle system and a control method. The heat cycle system includes: driving devices, one or a plurality of outdoor units, and a plurality of indoor units, which are connected by pipelines; a bypass pipeline for the plurality of indoor units, a bypass valve being disposed in the bypass pipeline; a pressure sensor that senses a pressure difference ?Po across the plurality of outdoor units; and a controller that is preset with a pressure difference set value ?Pset, wherein the controller calculates a pressure offset parameter ?P=?Po??Pset and adjusts an opening degree of the bypass valve based on the pressure offset parameter ?P so that the pressure offset parameter ?P approaches zero, and wherein the controller is preset with a first pressure offset threshold P1, and the controller is configured such that closed indoor units enter a bypass mode one by one when ?P>P1, until ?P?P1.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: March 7, 2023
    Assignee: CARRIER CORPORATION
    Inventors: Xiaohong Wang, Jian Ni, Liang Chang, Hui Zhai, Guangyu Shen, Qing Lu
  • Publication number: 20230023186
    Abstract: A semiconductor device includes a substrate, a 2-D material layer, source/drain contacts, and a gate electrode. The 2-D material layer is over the substrate, the 2-D material layer includes source/drain regions and a channel region between the source/drain regions, in which the 2-D material layer is made of a transition metal dichalcogenide (TMD). The source/drain contacts are in contact with source/drain regions of the 2-D material layer, in which a binding energy of transition metal atoms at the channel region of the 2-D material layer is different from a binding energy of the transition metal atoms at the source/drain regions of the 2-D material layer. The gate electrode is over the substrate.
    Type: Application
    Filed: January 13, 2022
    Publication date: January 26, 2023
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., National Yang Ming Chiao Tung University
    Inventors: Chiung-Yuan LIN, Tsung-Fu YANG, Weicheng CHU, Ching Liang CHANG, Chen Han CHOU, Chia-Ho YANG, Tsung-Kai LIN, Tsung-Han LIN, Chih-Hung CHUNG, Chenming HU
  • Publication number: 20230025999
    Abstract: An electronic device including an electronic unit and a functional unit is provided. The electronic unit includes a substrate, a plurality of semiconductor components, and a cover layer. The substrate has a plurality of first side surfaces. The semiconductor components are disposed on the substrate. The cover layer is disposed on the semiconductor components and has a plurality of second side surfaces. The functional unit is disposed on at least one of at least one of the first side surfaces and at least one of the second side surfaces.
    Type: Application
    Filed: June 27, 2022
    Publication date: January 26, 2023
    Applicant: Innolux Corporation
    Inventors: Hao-Jung Huang, Chi-Liang Chang, I-Ho Shen, Ker-Yih Kao, Yun-Sheng Chen, Chiao-Chu Tsui, Chih-Han Ma, Shan-Shan Hsu, Chia-Chieh Fan
  • Patent number: 11551587
    Abstract: An electronic device is disclosed and includes a base substrate, a circuit layer, and a plurality of light-emitting elements. The base substrate has a plurality of through holes, the circuit layer is disposed on the base substrate, and the light-emitting elements are disposed on the first circuit layer. An absolute value of a difference between two adjacent spacings of the plurality of through holes of the base substrate is less than 0.5 times radius of curvature of the electronic device when the electronic device is bent.
    Type: Grant
    Filed: January 3, 2022
    Date of Patent: January 10, 2023
    Assignee: InnoLux Corporation
    Inventors: Chin-Lung Ting, Chung-Kuang Wei, Li-Wei Mao, Chi-Liang Chang, Chia-Hui Lin
  • Patent number: 11543148
    Abstract: An air conditioning system and a control method thereof. The air conditioning system includes: a plurality of indoor units connected in parallel; a plurality of outdoor units connected in parallel; and a coolant circulation circuit which circulates coolant through each of the indoor units connected in parallel and each of the outdoor units connected in parallel respectively, and which exchanges heat with each of the indoor units and each of the outdoor units; wherein the air conditioning system further includes a controller which, based on a number of actively operating indoor units, a total number of the indoor units and a total number of the outdoor units, defines an upper limit of a number of actively operating outdoor units, so that the flow rate of the coolant flowing through the actively operating outdoor units is not lower than a preset flow rate.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: January 3, 2023
    Assignee: CARRIER CORPORATION
    Inventors: Xiaohong Wang, Hui Zhai, Jian Ni, Qing Lu, Liang Chang, Guangyu Shen
  • Publication number: 20220416497
    Abstract: A laser apparatus includes at least one electro-optic (EO) medium through which a polarized laser beam passes for N times, forming a plurality of first-pass to Nth-pass beams, by reflecting the polarized laser beam from at least one reflection mirror, and a power supplier configured to alternately provide a 1/N of a half-wave (?/2) or quarter-wave (?/4) voltage and remove the voltage to the EO medium, ? being a wavelength of the polarized laser beam. The at least one EO medium is tilted at angle ? and/or angle di with respect to one of the plurality of first-pass to Nth-pass beams. The at least one EO medium comprises a M number of EO mediums, and the power supplier is configured to alternately provide a 1/M*N of a half-wave (?/2) or quarter-wave (?/4) voltage and remove the voltage to each of the M number of EO mediums.
    Type: Application
    Filed: June 28, 2021
    Publication date: December 29, 2022
    Inventors: Liang Chang, Fangqin Li, Riccardo Leto
  • Patent number: 11527963
    Abstract: A control unit is provided. The control unit is configured to provide a control signal for controlling a power unit. The power unit includes a first positive voltage terminal, a second positive voltage terminal, a first negative voltage terminal, a second negative voltage terminal, and a switching element. The first negative voltage terminal and the second positive voltage terminal are coupled to each other in a short circuit manner. One terminal of the switching element is electrically connected to the first negative voltage terminal. The control unit is configured to: receive a pulse width modulation signal; receive a first power supply signal; receive a second positive voltage terminal signal; output a second power supply signal; and output the control signal for controlling the switching element to be turned on or turned off.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: December 13, 2022
    Assignee: DELTA ELECTRONICS, INC.
    Inventors: Da Jin, Xue-Liang Chang, Ya-Hong Xiong, Qing-Hua Su