Patents by Inventor Liang Guo

Liang Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11634702
    Abstract: A method for activating a cell-signaling pathway of interest in a cell, including applying a time-modulated localized alternating current electrical field to the cell, wherein the amplitude and frequency of the localized alternating current electrical field is selected to activate the cell signaling pathway of interest, thereby activating the cell signaling pathway.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: April 25, 2023
    Assignees: Arizona Board of Regents on behalf of Arizona State University, The Regents of the University of California
    Inventors: Quan Qing, John Albeck, Liang Guo, Min Zhao, Houpu Li
  • Patent number: 11634443
    Abstract: Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: April 25, 2023
    Assignee: United Therapeutics Corporation
    Inventors: Kenneth Robert Phares, Hitesh Batra, Liang Guo
  • Publication number: 20230088604
    Abstract: The disclosed technology relates to a busbar and thermal cut-off device (TCO) sub-assembly. The sub-assembly may be configured to be connected to a first battery cell and a second battery cell. The sub-assembly may comprise a first busbar configured to electrically connect the first battery cell to the second battery cell when the sub-assembly is connected to the first battery cell and the second battery cell. The sub-assembly may comprise a first TCO connected directly to the first busbar. The sub-assembly may not extend above a top surface of the first battery cell when the sub-assembly is connected to the first battery cell.
    Type: Application
    Filed: August 1, 2022
    Publication date: March 23, 2023
    Inventors: Brian J. Haskins, Jamie N. Forslin, Liang Guo, Jian Wang
  • Publication number: 20230083571
    Abstract: This application relates to batteries with an asymmetric design. At least some batteries described herein include two sections having different shapes and/or sizes, thus having different volumes. Having a battery formed with a relatively larger sections allows for several advantages. For example, the larger section can accommodate bending of a tab used to connect several electrodes together. Additionally, with the larger section providing space for the bent tab, the electrodes can be extended in, for example, the relatively smaller section. As a result, the battery can provide additional energy storage.
    Type: Application
    Filed: September 14, 2021
    Publication date: March 16, 2023
    Inventors: Liang GUO, Brian J. HASKINS, Premanand RAMADASS, Ghazal SHOORIDEH, Jamie N. FORSLIN, He LI, Abdifatah M. MOHAMED, Liubin ZHOU
  • Publication number: 20230041449
    Abstract: This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.
    Type: Application
    Filed: October 8, 2020
    Publication date: February 9, 2023
    Applicant: Monsanto Technology LLC
    Inventors: Liang Guo, David Kovalic, Bo-Xing Qiu, Jack Tabaska, Wei Wu
  • Patent number: 11566523
    Abstract: A microorganism curing anti-seepage device based on capsule transmission and control includes a stock bin which includes a mixing bin and an oil storage bin separated from the mixing bin. A feed pipe and an oil injection pipe are provided on the stock bin. A central shaft is rotatably provided within the mixing bin. A stirring component is provided on the central shaft. A delivery pipe is provided at a bottom portion of the mixing bin, an oil conduit is provided at a bottom portion of the oil storage bin, a jet pipe is provided at a junction of the oil conduit and the delivery pipe. Since microbial capsules are decomposed layer by layer, after the microbial capsules reach fissures, the microbial bacteria, the nutrient solution and the curing liquid are released step by step, and then calcium carbonate is induced by microorganisms to achieve solidification and anti-seepage of fissures.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: January 31, 2023
    Assignee: SOUTHWEST PETROLEUM UNIVERSITY
    Inventors: Liang Guo, Xiaoyu He, Junwei Zhang, Mingwei Liao, Hao Guo, Latie Abu, Chun Pei, Ziwei Xiao, Yiqi Peng
  • Patent number: 11560363
    Abstract: Provided are novel prodrugs of esuberaprost and pharmaceutical compositions thereof, as well as methods of making and methods of using these prodrugs.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: January 24, 2023
    Assignee: United Therapeutics Corporation
    Inventors: Hitesh Batra, Liang Guo
  • Publication number: 20230011483
    Abstract: The present disclosure relates to a method and device for adjusting a bit rate during live streaming. In the method for adjusting the bit rate during live streaming includes: a parameter of a network used by an anchor terminal for transmitting live streaming data is acquired, an adjustment range of the bit rate for uploading the live streaming data is determined based on the parameter of the network used by the anchor terminal for transmitting the live streaming data, and the bit rate for uploading the live streaming data by the anchor terminal is adjusted based on a determined adjustment range.
    Type: Application
    Filed: July 5, 2022
    Publication date: January 12, 2023
    Inventors: Chao ZHOU, Liang GUO, Bing YU
  • Patent number: 11553224
    Abstract: The present disclosure relates to a method and device for adjusting a bit rate during live streaming. In the method for adjusting the bit rate during live streaming includes: a parameter of a network used by an anchor terminal for transmitting live streaming data is acquired, an adjustment range of the bit rate for uploading the live streaming data is determined based on the parameter of the network used by the anchor terminal for transmitting the live streaming data, and the bit rate for uploading the live streaming data by the anchor terminal is adjusted based on a determined adjustment range.
    Type: Grant
    Filed: July 5, 2022
    Date of Patent: January 10, 2023
    Assignee: BEIJING DAJIA INTERNET INFORMATION TECHNOLOGY CO., LTD.
    Inventors: Chao Zhou, Liang Guo, Bing Yu
  • Publication number: 20220389337
    Abstract: A method for recovering C2 components in a methane-containing industrial gas includes the steps of (1) cooling a compressed methane-containing industrial gas and performing gas-liquid separation; (2) absorbing C2 components in the gas phase by using an absorbent to obtain an absorption rich liquid; (3) returning the absorption rich liquid to the compression in step (1) or mixing the absorption rich liquid with the liquid phase obtained in step (1) to obtain a mixed liquid, and depressurizing the mixed liquid or the absorption rich liquid; (4) performing methane desorption on the depressurized stream to obtain a rich absorbent, or performing second gas-liquid separation on the depressurized stream, followed by methane desorption on the second liquid phase to obtain a rich absorbent; and (5) desorbing and separating the rich absorbent to obtain a lean absorbent and an enriched gas, and recycling and reusing the lean absorbent.
    Type: Application
    Filed: September 24, 2020
    Publication date: December 8, 2022
    Inventors: Huawei SHAO, Dongfeng LI, Yi ZOU, Zhixin LIU, Chunfang LI, Liang GUO, Jingsheng ZHANG, Zhiyan HU
  • Publication number: 20220323387
    Abstract: Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.
    Type: Application
    Filed: December 13, 2021
    Publication date: October 13, 2022
    Applicant: United Therapeutics Corporation
    Inventors: Kenneth Robert Phares, Hitesh Batra, Liang Guo
  • Patent number: 11467541
    Abstract: A method for disassembling first and second watch-surfaces of a watch includes the steps of removing a decorative cover from the watch; rotating an adjusting screw to move an H-shaped snapping member toward a casing so that the H-shaped snapping member abuts against the adjusting screw; rotating a snapping ring so that an engaging protrusion does not overlap a pressing protrusion and the snapping ring can be removed from the casing; opening the watch; using a tool to press against a platform of the connecting sleeve; rotating the main screw to remove the connecting sleeve; removing the first watch-surface from the casing; removing first and second positioning rings and suspension columns; turning the casing to remove the snapping ring; opening the watch; using the tool to press against the platform; rotating the main screw to remove the connecting sleeve; and removing the second watch-surface from the casing.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: October 11, 2022
    Inventor: Jun-Liang Guo
  • Publication number: 20220315072
    Abstract: The present invention relates to a moving block train operation control method and system based on train autonomous positioning, where the method is centered on a train-mounted device, autonomous positioning and integrity checking are implemented for the train-mounted device through satellites, and a movement authority and a target distance curve are calculated according to a real-time position, speed, and line state of a preceding train and in combination with train-to-train communication train safety protection technology, thereby achieving moving block. Compared with the prior art, the present invention has the advantages that line use efficiency, system work efficiency and operation efficiency are improved, a quantity of railside devices is reduced, and system construction and maintenance costs are reduced.
    Type: Application
    Filed: October 19, 2020
    Publication date: October 6, 2022
    Inventors: Yajing ZHANG, Qingbiao XU, Xianliang XU, Tao WANG, Zhixin CHEN, Jiqing NA, Liang GUO
  • Patent number: 11441357
    Abstract: A drilling platform for amphibious operations includes: a base, wherein drive tracks are arranged on both sides of the base, a propeller is disposed at a rear end of the base, and a driving assembly is disposed inside the base; two support cylinders are respectively disposed at two ends of the base; each of the support cylinders contains a sub-cylinder; a pushing cylinder is arranged on a bottom surface of the partition plate; a buoyancy adjustment assembly is provided at a bottom of the base, so as to provide buoyancy support for the base when the base is transferred from land to water. The present invention is suitable for drilling construction of pile foundations of water and land buildings, bridge piers, and transmission line electric tower pile foundations, as well as drilling of oil wells, wherein the drilling platform construction process at different drilling points is omitted.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: September 13, 2022
    Assignee: SOUTHWEST PETROLEUM UNIVERSITY
    Inventors: Junwei Zhang, Liang Guo, Chun Pei, Ziwei Xiao, Mingwei Liao, Baoquan Wang, Deliang Qian, Youjun Ji, Jiao Zhu, Hui Guo
  • Publication number: 20220280430
    Abstract: Provided are treprostinil derivatives with a reduced ability to form undesired impurities in a pharmaceutical formulation, such as a dry powder formulation, further containing a carboxyl group containing inactive ingredient, such as fumaryl diketopiperazine.
    Type: Application
    Filed: March 2, 2022
    Publication date: September 8, 2022
    Applicant: United Therapeutics Corporation
    Inventors: Hitesh Batra, Liang Guo, Patrick Poisson, Susovan Jana
  • Patent number: 11431643
    Abstract: Embodiments of the application can provide a method, a device, and a terminal for controlling a jitter in network communication, belonging to the technical field of communication. The method includes: generating trigger information, where the trigger information is for triggering switching of a jitter control strategy for the network communication, the jitter control strategy includes a first control strategy based on a first cached data amount and a second control strategy based on a second cached data amount, and the first cached data amount is smaller than the second cached data amount; switching the jitter control strategy to a target control strategy in response to the trigger information; and controlling the jitter in the network communication by using the target control strategy, where the target control strategy is the first control strategy or the second control strategy corresponding to the trigger information.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: August 30, 2022
    Assignee: BEIJING DAJIA INTERNET INFORMATION TECHNOLOGY CO., LTD
    Inventors: Chen Zhang, Liang Guo, Wenhao Xing
  • Patent number: 11396748
    Abstract: A T-shaped shear wall module including a straight pattern plate, two L-shaped pattern plates with a same structure, and connectors. Each of the two L-shaped pattern plates includes a first pattern plate and a second pattern plate which are perpendicular to each other. In a direction perpendicular to the straight pattern plate, the two first pattern plates are arranged in parallel to each other and both extend in a direction away from the straight pattern plate, and a plurality of connectors are rigidly arranged between two first pattern plates. Along a direction parallel to the straight pattern plate, two second pattern plates are coplanar and extend in opposite directions, and a plurality of connectors are rigidly arranged between the straight pattern plate and the two second pattern plates. The present application also provides a shear wall and a construction method thereof.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: July 26, 2022
    Assignee: XI'AN UNIVERSITY OF ARCHITECTURE AND TECHNOLOGY
    Inventors: Jiping Hao, Qiang Xue, Xiaoling Sun, Liang Guo, Hanchao Liu
  • Publication number: 20220204953
    Abstract: Disclosed is a mutant of acid phosphatase and an application thereof, belonging to the technical field of biological engineering. The disclosure provides a mutant of acid phosphatase PaAPaseMu3. By expressing the mutant of acid phosphatase PaAPaseMu3 in Escherichia coli and using a whole-cell conversion method, L-ascorbic acid is transformed into L-ascorbate-2-phosphate. Moreover, a catalytic system of the mutant of acid phosphatase PaAPaseMu3 is optimized from the aspects of reaction pH and temperature, so that a yield of L-ascorbate-2-phosphate can reach 90.1 g/L and a molar yield can reach 75.1%. Therefore, the problems of a high substrate cost, environmental pollution and the like before are greatly reduced, laying a foundation for the industrial green production of L-ascorbate-2-phosphate.
    Type: Application
    Filed: March 15, 2022
    Publication date: June 30, 2022
    Inventors: Liming Liu, Xin Xu, Wei Song, Xiulai Chen, Jia Liu, Cong Gao, Jing Wu, Liang Guo
  • Publication number: 20220162631
    Abstract: This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.
    Type: Application
    Filed: August 27, 2021
    Publication date: May 26, 2022
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Liang GUO, David K. KOVALIC, Bo-Xing QIU, Jack E. TABASKA, Wei WU
  • Patent number: 11336257
    Abstract: A method for manufacturing a semiconductor device includes providing a substrate having a front surface and a back surface, forming first and second through holes in the substrate, filling the first and second through holes with metals, forming a subassembly on the front surface of the substrate. The subassembly includes a first metal layer and a second metal layer insulated from the first metal layer, the first metal layer is electrically connected to the metal filled in the first through hole, the second metal layer is electrically connected to the metal filled in the second through hole, and a metal connection pad is on the substrate and surrounds the subassembly. The method also includes providing a cap assembly including a metal connection member, bonding the cap assembly to the subassembly, and thinning the back surface of the substrate to expose the first and second through holes.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: May 17, 2022
    Assignee: Semiconductor Manufacturing International (Shanghai) Corporation
    Inventor: Liang Liang Guo