Abstract: A spiral impact drilling machine applicable to rock and soil and a construction method are provided. The drilling machine includes a rock chiseling part, a soil drilling part, a gear, a drill rod, and a drill bit. The rock chiseling part includes an air cylinder. A piston is arranged in the air cylinder. The top of the piston is fixedly connected with to a turbine fan blade. The bottom of the piston is fixedly connected to a force transferring component. The soil drilling part includes a motor. The motor is arranged in the force transferring component. The inner part of the gear is in nested connection with the drill rod. The outer part of the gear is in engaged connection with each of the bottom of the force transferring component and the motor. The bottom of the gear is fixedly connected to the drill rod through a stress component.

Abstract: A method and an apparatus for displaying information flow, a storage medium and an electronic device are provided. The method includes: dividing a predetermined display time period for the first-type display information into multiple sub-time periods; determining, for the sub-time periods, a segmented display target of each piece of first-type display information in the sub-period based on a display target of the first-type display information in the predetermined display time period; and determining, for each display position, target display information to be allocated to the display position from the information flow, based on an estimated click-through rate of the display position, a proposed value of the second-type display information, historical display data of the first-type display information, and a segmented display target of the first-type display information in a current sub-time period.

Abstract: A diversified assembly printed circuit board includes a first printed circuit board provided with a multiple first conductive metals protruding from a surface of the first printed circuit board, and a multiple second printed circuit boards each provided with a multiple second conductive metals protruding from a surface of the each of the second printed circuit boards. At a connection position, solidified conductive metal paste is arranged between each of the first conductive metals and a corresponding second conductive metal to electrically connect each of the first conductive metals and the corresponding second conductive metal. A laminated adhesive sheet is arranged between each of the second printed circuit boards and the first printed circuit board to physically connect the second printed circuit boards and the first printed circuit board.

Abstract: The present disclosure generally relates to a DNA construct design system. An exemplary method comprises, at an electronic device, receiving an input selecting a vector backbone, wherein the vector backbone comprises a plurality of functional parts; in response to receiving the input selecting the vector backbone, displaying a graphical representation of the vector backbone; receiving an input selecting one or more functional parts of the plurality of functional parts of the vector backbone; after receiving the input selecting one or more functional parts on the vector backbone, receiving a drag-and-drop input comprising an indication of a functional part; in response to receiving the drag-and-drop input, updating the vector backbone based on the functional part indicated in the drag-and-drop input and the selected one or more functional parts of the plurality of functional parts of the vector backbone; and displaying a graphical representation of the updated vector backbone.

Abstract: A multiplex proteome quantification method based on isobaric dimethyl labeling implements dimethyl labeling of peptide N-terminal in an acidic condition and C-terminal in an alkaline condition one after another by means of Hall the property that a dimethylation reaction has different rates on an amino group at the peptide N-terminal and an amino group on a Lysine side chain at the peptide C-terminal in the acidic condition. Multiplex labeling of peptide samples is implemented by means of the organic combination of various isotope forms of a dimethyl labeling reagents. The mass-to-charge ratios in MS1 of peptides after multiplex labeling are completely the same, the mass-to-charge ratios of the fragment ions in MS2 are different, and multiplex quantitative analyses are carried out by extracting the intensity values of corresponding fragment ions in the MS2.

Abstract: The present invention discloses a coagulation analyzer and a coagulation analysis method which relate to the technical field of medical instruments. The coagulation analyzer includes an optical coagulation analysis module, a sample interference analysis module, a magnetic coagulation analysis module, and a test transfer module. The coagulation analyzer uses the sample interference analysis module to determine whether an interferent in the sample has effect on the coagulation test result of the optical coagulation analysis module. If the interferent in the sample has no effect on the coagulation test result, the optical coagulation analysis module is used to perform the coagulation analysis and report the test result. If the interferent in the sample has effect on the coagulation test result, the test transfer module is used to transfer the test to the magnetic coagulation analysis module to perform the coagulation analysis and report the test result.

Abstract: The present invention provides a silica aerogel powder, a preparation method and an application thereof, and belongs to the field of preparation of insulating materials. The silica aerogel powder provided by the present invention is prepared from the following components: 100 to 300 parts by weight of aqueous solution of silica source, 200 to 400 parts by weight of oil phase solvent, 4 to 40 parts by weight of cosolvent, 0.2 to 2 parts by weight of surfactant, 10 to 60 parts by weight of sodium methylsiliconate solution, 1 to 5 parts by weight of aqueous inorganic acid solution, 3 to 10 parts by weight of sodium trimethylsilanolate solution in tetrahydrofuran (THF), and 0.3 to 0.9 part by weight of organic fatty acid in petroleum ether. The silica aerogel powder provided by the present invention is structurally uniform and features good hydrophobicity, low thermal conductivity, and low density.

Abstract: A diversified assembly printed circuit board includes a first printed circuit board provided with a multiple first conductive metals protruding from a surface of the first printed circuit board, and a multiple second printed circuit boards each provided with a multiple second conductive metals protruding from a surface of the each of the second printed circuit boards. At a connection position, solidified conductive metal paste is arranged between each of the first conductive metals and a corresponding second conductive metal to electrically connect each of the first conductive metals and the corresponding second conductive metal. A laminated adhesive sheet is arranged between each of the second printed circuit boards and the first printed circuit board to physically connect the second printed circuit boards and the first printed circuit board.

Abstract: A nanocrystal production method includes a light irradiation step of applying light to a surface of a metal material immersed in water to form nanocrystals on the surface. In this nanocrystal production method, the metal material contains iron, the nanocrystal contains at least one of iron oxide and iron hydroxide, and in the spectrum of the light, a wavelength at which the intensity is maximum is not less than 360 nm and less than 620 nm.

Abstract: A method and an apparatus for displaying information flow, a storage medium and an electronic device are provided. The method includes: dividing a predetermined display time period for the first-type display information into multiple sub-time periods; determining, for the sub-time periods, a segmented display target of each piece of first-type display information in the sub-period based on a display target of the first-type display information in the predetermined display time period; and determining, for each display position, target display information to be allocated to the display position from the information flow, based on an estimated click-through rate of the display position, a proposed value of the second-type display information, historical display data of the first-type display information, and a segmented display target of the first-type display information in a current sub-time period.

Abstract: In the technical field of metal melting, a unisource high-strength ultrasound-assisted method for casting large-specification 2XXX series aluminum alloy round ingots applies in an ingot guiding process, a unisource high-strength ultrasonic vibration system to the center of a hot-top crystallizer, ultrasound directly acts on the center position of a crystallizer, and enough ultrasonic field energy is provided for a melt by controlling the power of the ultrasonic vibration system, so that an aluminum alloy solidification process is implemented under the effect of ultrasound, homogenization of microstructures and components of ingots is promoted, and the existing problems that microstructures are thick and crystal phases are enriched due to slow cooling of centers of large-specification round ingots are effectively solved, meanwhile, the problems of great operation difficulty and heavy workload during multisource ultrasonic coupling are avoided.

Abstract: A codon optimization method based on an immune algorithm is characterized in that an immune algorithm and a genetic algorithm are successively used to respectively perform local multi-objective optimization and global multi-objective optimization on a protein coding sequence, and then an exhaustive method is used to perform fine adjustment and optimization on the sequence, so as to search the optimal expression sequence to the greatest extent. The present invention not only retains the characteristic of random global parallel search of the genetic algorithm, but also avoids premature convergence to a comparatively great extent to ensure rapid convergence to the global optimal solution.

Abstract: The present invention belongs to the technical field of biological pharmacy, and particularly relates to a long-acting HM-3 fusion protein molecule and an application thereof. In the present invention, on the basis of the sequence of HM-3 molecule, an active polypeptide HM-3 and derivatives thereof are linked to a human Fc (IgG) fragment or a fragment of an Fc (IgG) mutant directly or by a linker peptide (Linker), thus forming a novel molecular entity. The general formula of the molecular entity is (HM-3)n-Linker-Fc(IgG), Fc(IgG)-Linker-(HM-3)n, or (HM-3)n-Linker-Fc(IgG)-Linker-(HM-3)n. The fusion protein effectively prolongs the half-life of HM-3, is low in cost and overcomes the major problem of druggability of small peptides. Therefore, the fusion protein of the present invention may serve as a potential drug for the treatment of autoimmune diseases, neovascular diseases, osteoarthritis and the like.

Abstract: The present invention provides a method for drying high-stability microcapsule particles containing multiple double bonds fat soluble nutrients comprises: a) preparing a microcapsule emulsion containing multiple double bonds fat soluble nutrients, performing spray granulation on the microcapsule emulsion in a spray system (1), and meanwhile blasting air into the spray system (1), the blasted air wrapping adsorption materials, and the microcapsule emulsion being immediately solidified and sized after coming into contact with the air, so as to obtain liquid droplets having surfaces to which adsorption materials are adsorbed; b) performing fluidized drying on the liquid droplets having surfaces to which the adsorption materials are adsorbed in the step a) in a multi-stage fluidized bed system (5); c) collecting non-adsorbed adsorption materials by means of an adsorption material dust removal, recovery and circulation system; and d) collecting microcapsule particle products.

Abstract: An unmanned aerial vehicle (UAV) with omnidirectional thrust vectoring includes a central unit, a connective structure, and a plurality of propulsion units with omnidirectional thrust vectoring allowing a full six degrees of freedom. A vectored propulsion unit comprises thruster vectored by an omnidirectional mechanism and may include an autonomous sub-vehicle housed within a rotational frame, or an actuator-thruster assembly with directional control. A UAV with omnidirectional thrust vectoring includes a control system with a ground station unit, a central flight control unit, and a propulsion control unit. A plurality of vectored propulsion units working in coordination allows an unmanned aerial vehicle to maneuver with any stance or body orientation.

Abstract: The present disclosure discloses a microwave flash evaporation process and apparatus and uses thereof. A microwave flash evaporation process, wherein the process makes integration of those technologies for liquid spraying, liquid droplet flash evaporation, microwave enhancement, vacuum steam discharge, and simulation and optimization of multi-mode resonant cavity, wherein through the coupling effect of the microwave, by means of one stage microwave flash evaporation, the effect normally achieved by multi-effect evaporation and flash evaporation is obtained and a liquid droplet micro-system with microwave energy transfer in situ is formed so as to prevent a circulation pump and a steam heat exchange system from being corroded under high temperature and high pressure, and prevent scaling on a heat exchanger, and improve evaporation efficiency.

Abstract: The present invention provides a method of preparing highly stable microcapsule powders or microparticles containing a fat-soluble nutrient having multiple double bonds.

Abstract: The invention relates to a method for the treatment of body fluid proteins, by which proteins from body fluids such as blood or urine are extracted by adding a certain proportion of high molecular polymer solution under low temperature condition followed by denaturation and reduction by adding a certain concentration of surfactant and tris(2-carboxyethyl) phosphine (TCEP) under a high temperature condition. Subsequently, the iodoacetic acid brushes grafted on silica microspheres called as solid-phase alkylation reagents are added into protein solution, which can react rapidly with the protein sulfhydryl group. After centrifugation, the microspheres are obtained and repeatedly washed with methanol and buffer to remove interferences such as sugars, salts, surfactants, lipids to obtain high-purity proteins, and finally protease is added to digest proteins into peptides. After centrifugation, the peptide products are obtained, and directly analyzed by liquid chromatography-mass spectrometry (LC-MS) system.

Abstract: An integrated system has functions of high-abundance protein depletion, on-line denaturation and reduction of middle and low-abundance proteins, desalting and protein digestion. This system includes an antibody column for the depletion of high-abundance protein from body fluids, clustering hollow fiber membranes based high temperature denaturator and reducer, solvent exchanger and immobilized enzymatic reactor. The protein sample from body fluid is firstly treated by antibody column to remove the high-abundance proteins, and then the eluted medium-low abundance protein is subjected to on-line, rapid denaturation and reduction by a high-temperature denaturator and reducer, subsequently the denaturing and the reducing agents in proteins are removed by a solvent exchanger, finally the purified proteins were enzymatically hydrolyzed by an immobilized enzymatic reactor. The peptides produced by the enzymatic hydrolysis can be analyzed by mass spectrometry (MS).

Abstract: A nanocrystal production method includes a light irradiation step of applying light to a surface of a metal material immersed in water to form nanocrystals on the surface. In this nanocrystal production method, the metal material contains iron, the nanocrystal contains at least one of iron oxide and iron hydroxide, and in the spectrum of the light, a wavelength at which the intensity is maximum is not less than 360 nm and less than 620 nm.