Abstract: Use of a mulberry extract in the preparation of a product for treating and/or improving polycystic ovarian syndrome. It is demonstrated in the experiment that the mulberry twig alkaloids can reduce the ovarian weight of rats with polycystic ovarian syndrome and improve the ovarian pathology, regulate the estrous cycle of rats with polycystic ovarian syndrome in the intervention process, and can remarkably adjust the secretion level of sex hormones in rats with polycystic ovarian syndrome.

Abstract: The present disclosure discloses a method for preparing a polyurethane foam using an extract of cotton spinning black liquor, including the following steps: step (1): extracting biomass in cotton spinning black liquor by acid precipitation to obtain the extract of cotton spinning black liquor; step (2): pretreating the extract of cotton spinning black liquor, and uniformly mixing the pretreated extract of cotton spinning black liquor with a polyether polyol to obtain a mixed raw material; and step (3): preparing the polyurethane foam from the mixed raw material, dibutyltin dilaurate, distilled water, a foam stabilizer, aluminum hypophosphite and an isocyanate by one-step foaming. The present disclosure can solve the problems of high treatment cost and low utilization rate of the existing cotton spinning black liquor.

Abstract: A computer-implemented method for data communication bus address sharing can include selecting, by at least one processor, one of two or more peripheral devices sharing an address of a data communication bus. The method can additionally include modulating, by the at least one processor, a duty cycle of a clock signal transmitted over the data communication bus to the two or more peripheral devices, wherein the modulating causes a low period of the clock signal to satisfy a threshold condition for indicating selection of the selected one of the two or more peripheral devices. The method can also include performing, by the at least one processor using the address, data communication over the data communication bus with the selected one of the two or more peripheral devices. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention discloses a gene mining method and system based on transcriptome and DNA methylome. The gene mining method comprises: acquiring samples; performing transcriptome sequencing on the samples and analyzing data obtained by the sequencing to obtain differentially expressed genes; performing DNA methylation sequencing on the samples and analyzing data obtained by the sequencing to obtain differentially methylated genes; performing gene function enrichment on the obtained differentially expressed genes and differentially methylated genes to obtain a molecular protein-protein interaction (PPI) network; and performing gene clustering with the molecular PPI network to identify target genes. The present invention solves the problems that it takes time and effort to mine core genes of existing transcriptome and methylome and the result is not accurate enough. The present invention mines target genes by organically integrating originally isolated transcriptome data and DNA methylome data.

Abstract: Secondary battery and preparation method thereof are provided. Lithium source, iron source, phosphorus source, transition metal salt source, bismuth source, and solvent are mixed to obtain intermediate solution. PH of intermediate solution ranges from 1.0 to 4.0. Intermediate solution is subjected to hydrothermal reaction, to obtain precursor by drying. Precursor is subjected to heat treatment to obtain core. Core includes lithium iron phosphate and bismuth salt. Core is coated with coating material to obtain cathode material. Cathode material includes core and conductive polymer coating layer arranged on at least surface of core. Finally, cathode material is prepared into secondary battery. Cathode material in present disclosure has advantages of high compaction density and high conductivity, which can significantly enhance energy density, cycle performance, and high-and-low temperature performance when cathode material is applied to secondary battery.

Abstract: Disclosed in the present disclosure is a method for producing hydrogen from woody waste through staged pyrolysis and catalytic gasification. The method includes: performing baking pretreatment on the woody waste; thermally activating aluminum smelting waste residues, and mixing the thermally activated aluminum smelting waste residues with the baked woody waste; pyrolyzing and gasifying the mixture for hydrogen production to obtain primary pyrolysis gas and a carbon-aluminum composite material; and further catalytically cracking the obtained primary pyrolysis gas by taking the obtained carbon-aluminum composite material as a catalyst.

Abstract: The disclosure relates to the technical field of preparing the metal material of magnesium alloy, and particularly provides a method for preparing biomedical magnesium alloy wires. The magnesium, zinc, and neodymium alloys are subject to smelting, casting, rolling, and other processes to prepare plates. The plates are subjected to a special mechanical stirring process to prepare a processing zone with the same thickness as the plates. After machining, the processing zone is used as the final product of the wire or drawn in multiple passes to finally form the wire with the required diameter.

Abstract: Disclosed herein are invariant natural killer T (iNKT) cells engineered using hematopoietic stem and progenitor cells (HSPCs) and methods of making and using thereof.

Abstract: A magnetic resonance imaging (MRI) system and method integrating multi-nuclide synchronous imaging and spectral imaging is provided. The MRI system includes a spectral imaging module, a multi-nuclide synchronous imaging module, and a spectral reconstruction and image fusion module, where the spectral imaging module is configured to acquire a spectrum of a nuclide Nuc; the multi-nuclide synchronous imaging module is configured to perform synchronous imaging of nuclides Nuc1 . . . Nucn, where when n=1, Nucl is 1H; and when n>1, Nucn is a non-1H nuclide; and the spectral reconstruction and image fusion module is configured to receive the spectrum of the nuclide Nuc and images of the nuclides Nuc1 . . . Nucn, and acquire spatial distribution information of compounds of the nuclide Nuc and spatial distribution information of the non-1H nuclide through fusion. The system and method can synchronously acquire MR signals of different nuclides, and reconstruct and fuse non-1H nuclide images.

Abstract: A system and method for authenticating users of a data processing platform stores a mapping of a unique user platform identifier to multiple user identity provider identifiers associated with multiple realms for a same user. In some examples, the method includes receiving a request from a client device to establish an access session to perform one or more actions on data of the data processing platform and receiving, from at least one of the first external identity provider of the first realm or the second external identity provider of the second realm, a user identity provider identifier associated with the request. In certain examples, the method includes granting permission to perform the one or more actions on the data of the data processing platform based at least in part on the received user identity provider identifier.

Abstract: A magnetic resonance imaging (MRI) system and method integrating multi-nuclide synchronous imaging and spectral imaging is provided. The MRI system includes a spectral imaging module, a multi-nuclide synchronous imaging module, and a spectral reconstruction and image fusion module, where the spectral imaging module is configured to acquire a spectrum of a nuclide Nuc; the multi-nuclide synchronous imaging module is configured to perform synchronous imaging of nuclides Nuc1 . . . . Nucn, where when n=1, Nucl is 1H; and when n>1, Nucn is a non-1H nuclide; and the spectral reconstruction and image fusion module is configured to receive the spectrum of the nuclide Nuc and images of the nuclides Nuc1 . . . . Nucn, and acquire spatial distribution information of compounds of the nuclide Nuc and spatial distribution information of the non-1H nuclide through fusion. The system and method can synchronously acquire MR signals of different nuclides, and reconstruct and fuse non-1H nuclide images.

Abstract: The invention relates to the field of oilfield chemistry, and discloses a self-repairing plugging gel polymer for drilling fluid, a preparation method and application thereof, and the drilling fluid containing the gel polymer, wherein the polymer contains a structural unit A, a structural unit B, a structural unit C and a structural unit D, and the structural unit A is a structural unit with a structure shown in the formula (1); the structural unit B is a structural unit with a structure shown in the formula (2); the structural unit C is a structural unit with a structure shown in the formula (3); the structural unit D is a structural unit having a structure represented by the formula (4).

Abstract: A lifting device for building a steel structure hoistway and a method for building a steel structure hoistway. The lifting device includes a lifting mechanism and a crane mechanism. The lifting mechanism includes a bottom platform, a middle platform and a top platform. The crane mechanism is arranged on the top platform of the lifting mechanism, and includes a base and a crane on the base. The base is arranged on the top platform and is rotatable relative to the top platform along a vertical axis, and the hanger frame of the crane is movable between a vertical orientation and an inclined orientation. The lifting mechanism is configured to ascend and descend in the constructed steel structure hoistway, and the crane mechanism is configured to lift building materials, such as steel beams, steel columns, etc., for use in building the steel structure hoistway to their designed installation locations.

Abstract: A system and method for authenticating users of a data processing platform stores a mapping of a unique user platform identifier to multiple user identity provider identifiers associated with multiple realms for a same user. In some examples, the method includes receiving a request from a client device to establish an access session to perform one or more actions on data of the data processing platform and receiving, from at least one of the first external identity provider of the first realm or the second external identity provider of the second realm, a user identity provider identifier associated with the request. In certain examples, the method includes granting permission to perform the one or more actions on the data of the data processing platform based at least in part on the received user identity provider identifier.

Abstract: A lifting device for building a steel structure hoistway and a method for building a steel structure hoistway. The lifting device includes a lifting mechanism and a crane mechanism. The lifting mechanism includes a bottom platform, a middle platform and a top platform. The crane mechanism is arranged on the top platform of the lifting mechanism, and includes a base and a crane on the base. The base is arranged on the top platform and is rotatable relative to the top platform along a vertical axis, and the hanger frame of the crane is movable between a vertical orientation and an inclined orientation. The lifting mechanism is configured to ascend and descend in the constructed steel structure hoistway, and the crane mechanism is configured to lift building materials, such as steel beams, steel columns, etc., for use in building the steel structure hoistway to their designed installation locations.

Abstract: Systems and methods generate a first security node hash identifier by performing a first hash operation, such as a one-way hash, on a first data resource identifier associated with a first data resource, such as a data set, produced by a data resource platform. The systems and methods generate a dependent second security node hash identifier by performing a second hash operation on a second data resource identifier associated with a dependent second data resource produced by the data resource platform and on the first security node hash identifier, receive an access request for access to the dependent second data resource; and in response to the access request, grant permission to access the dependent second data resource to a user associated with the access request based on the dependent second security node hash identifier.

Abstract: We have discovered MAO-A induction in mouse and human TAMs. Moreover, we determined that MAO-A-deficient mice exhibited decreased TAM immunosuppressive functions corresponding with enhanced antitumour immunity. Building upon these discoveries, we then determined that MAOI treatment induced TAM reprogramming and suppressed tumour growth in preclinical mouse syngeneic and human xenograft tumour models. Surprisingly, combining MAOI and anti-PD-1 treatments resulted in synergistic tumour suppression. Together, these data identify MAO-A as a critical regulator of TAMs, and that show that repurposing MAOIs for TAM reprogramming can be used to improve cancer immunotherapies.

Abstract: Monoamine oxidase A (MAO-A) is an enzyme best known for its function in the brain, where it breaks down neurotransmitters and thereby influences mood and behavior. While small molecule MAO inhibitors (MAOIs) have been developed used for treating depression and other neurological disorder, the involvement of MAO-A in antitumor immunity has not been known. The disclosure provided herein identifies MAO-A as an immune checkpoint and the use of MAOI antidepressants for cancer immunotherapy. Here we report induction of the Maoa gene in tumor-infiltrating immune cells. MAOI treatment significantly suppressed tumor growth in preclinical mouse syngeneic and human xenograft tumor models in a T cell-dependent manner. Combining MAOI and anti-PD-1 treatments generated synergistic tumor suppression effects. Clinical data correlation studies associated intratumoral MAOA expression with T cell dysfunction and impaired patient survival in a broad range of cancers.

Abstract: Systems and methods generate a first security node hash identifier by performing a first hash operation, such as a one-way hash, on a first data resource identifier associated with a first data resource, such as a data set, produced by a data resource platform. The systems and methods generate a dependent second security node hash identifier by performing a second hash operation on a second data resource identifier associated with a dependent second data resource produced by the data resource platform and on the first security node hash identifier, receive an access request for access to the dependent second data resource; and in response to the access request, grant permission to access the dependent second data resource to a user associated with the access request based on the dependent second security node hash identifier.

Abstract: The present invention relates to the field of petroleum industry phase oilfield chemistry, and specifically relates to a bionic and dual-phobic drilling fluid. The drilling fluid contains a bionic wall-fixing agent, a bionic lubricant, a super dual-phobic agent, a scrap-carrying agent and a bionic shale inhibitor. The present invention uses the theory of bionics and the theory of a downhole rock surface being double phobic as a basis. By means of using the bionic wall-fixing agent, the bionic lubricant, the super dual-phobic agent, the scrap-carrying agent and the bionic shale inhibitor, which have special properties of imitating animals and plants in nature, and using a series of bionic treatment agents, a set of bionic and dual-phobic drilling fluid systems, which corresponds to an unconventional, complex oil and gas well, is formed.