Abstract: A synthesis method of a targeted drug nCoVshRNA.2ACE2 of a COVID-19 virus, which includes the following steps: designing a consensus RNAi sequence siRNA of the COVID-19 virus and a variant strain thereof; synthesizing two complementary siRNAs into a small hairpin-shaped shRNA with a loop, and synthesizing ACE2 or a cell penetrating peptide ACE2 with a receptor-binding domain (RBD) as a ligand; and ligating the ACE2 to a sense strand and an antisense strand of the shRNA separately to synthesize the nCoVshRNA.2ACE2 including a shRNA region and an ACE2 region. The bivalent ACE2 functions to neutralize the RBD and deliver the shRNA in a targeted manner; an “shRNA-ACE2-RBD-virus” complex bridged by the ACE2 allows the shRNA to enter target cells with virus infection, thereby avoiding a side effect of non-specific delivery of the shRNA to uninfected cells, as well as resisting the variant strain and neutralizing the virus with the ACE2.

Abstract: The present disclosure relates to a display panel (10) and a method of manufacturing the same. The display panel (10) includes a substrate (101), a number of light transmissive units (320), and an package layer (600). The substrate (101) has a light transmissive region (700) and a pixel display region (800). The light transmissive region (700) and the pixel display region (800) are complementarily disposed with respect to the substrate (101). The plurality of light transmissive units (320) are disposed in the light transmissive region (700) and overlay a surface of the substrate (101) within the light transmissive region (700). The package layer (600) overlays a surface of a number of light transmissive units (320). In the present disclosure, the substrate (101) has a different structure in the light transmissive region (700) and the pixel display region (800).

Abstract: The present disclosure provides a preparation method of an artificial antibody. The preparation method includes the following steps: screening a target siRNA from a conserved gene or a microsatellite of a coronavirus, synthesizing a small hairpin RNA (shRNA) that has a loop by complementary sense and antisense strands of the siRNA, synthesizing an ACE2 capable of binding to a receptor-binding domain (RBD), and synthesizing the artificial antibody including an shRNA region and an ACE2 region by ligating the ACE2 to sense and antisense strands of the shRNA separately. The bivalent ACE2 is used for neutralization of the RBD and targeted delivery of the shRNA; the shRNA is ligated to the virus through the ACE2 and enters target cells with virus infection, thereby avoiding a side effect of non-specific delivery of the shRNA to uninfected cells, as well as resisting the variant strain and neutralizing the virus with the ACE2.

Abstract: A management system includes: a plurality of machine tools each including a base plate; a plurality of storage plates; an object holder enabling an object to be placed thereon; a conveying unit including a fetching unit that is configured to secure or release said object holder, and a bridge crane that is configured to move the fetching unit among the base plates and the storage plates; and a control unit controlling the bridge crane to move the fetching unit to where the object holder is located, and controlling the fetching unit to secure the object holder, and controlling the bridge crane to move the fetching unit along with the object holder to another location to release the object holder.

Abstract: A die sorter tool may include a first conveyor, and a first lane to receive, from one or more load ports and via the first conveyor, a carrier with a set of dies. The die sorter tool may include a die flip module to receive the carrier from the first lane, manipulate one or more dies of the set of dies by changing orientations of the one or more dies, and return the one or more dies to the carrier after manipulating the one or more dies and without changing positions of the one or more dies within the carrier. The die sorter tool may include a second conveyor, and a second lane to receive, via the second conveyor, the carrier from the die flip module, and provide, via the first conveyor, the carrier to the one or more load ports.

Abstract: Provided are a method and apparatus for determining pose information of a robot, a device and a medium. The method includes: fitting a target curve according to a motion trajectory of an image module relative to a target label when the robot rotates; determining a coordinate offset of the image module relative to a body of the robot according to the target curve, and determining a relative distance between the image module and the target label according to the image module; and determining the pose information of the robot according to the coordinate offset and the relative distance.

Abstract: A coil decoupling method for a magnetic resonance imaging device, including: sending an instruction causing a transmitter to send a transmitted signal, acquiring a received signal received by a receiver, wherein the received signal is a signal arriving at the receiver after the transmitted signal passes through two coils to be adjusted of a plurality of coils, determining the coupling value between the two coils to be adjusted based on the transmitted signal and the received signal, and sending an instruction for adjusting a decoupling component based on the coupling value.

Abstract: A die sorter tool may include a first conveyor, and a first lane to receive, from one or more load ports and via the first conveyor, a carrier with a set of dies. The die sorter tool may include a die flip module to receive the carrier from the first lane, manipulate one or more dies of the set of dies by changing orientations of the one or more dies, and return the one or more dies to the carrier after manipulating the one or more dies and without changing positions of the one or more dies within the carrier. The die sorter tool may include a second conveyor, and a second lane to receive, via the second conveyor, the carrier from the die flip module, and provide, via the first conveyor, the carrier to the one or more load ports.

Abstract: Provided is a circulating aquaculture facility for saltwater ponds. The circulating aquaculture facility comprises a cultivation tank, a division plate vertically arranged in the cultivation tank to divide an inner cavity of the cultivation tank into a left inner chamber and a right inner chamber; a water inlet pipeline, water in the water inlet pipeline enters the cultivation tank through the left rectangular through hole of the cultivation tank; an outlet pipeline, sewage discharged from the right rectangular through hole of the cultivation tank is capable of entering the outlet pipeline; and an oxygen supply device which delivers oxygen to the inner bottom of the cultivation tank.

Abstract: A control system for evaluating residual operating life of a machine component of a machine tool includes a sensor and a control system. The sensor is disposed on the machine tool and is configured to sense movement of the machine component. The control device is configured to calculate a length of time based on a sense signal received from the sensor and sampled at a time point right after the machine component is freshly oiled, and to enable output of an alarm when determining that the length of time thus calculated is smaller than a predetermined length.

Abstract: Disclosed are an organic light emitting diode, a display panel and a display device. The organic light emitting diode includes a first electrode, a second electrode, a light emitting layer and an electron blocking layer, the first electrode and the second electrode are disposed opposite to each other, the light emitting layer is disposed between the first electrode and the second electrode, the electron blocking layer is disposed between the light emitting layer and the first electrode. A LUMO level of the electron blocking layer is higher than a LUMO level of a light emitting host material in the light emitting layer, a first level difference between the LUMO level of the electron blocking layer and the LUMO level of the light emitting host material in the light emitting layer is represented by A, where A?0.4 eV.

Abstract: A variable-frequency generator set integrated system driven by an internal combustion engine includes a permanent magnet generator and an inverter device. The winding coils on the permanent magnet generator stator are all three-phase winding coils. The inverter device has an AC-DC rectification and voltage stabilization unit, a DC-AC variable-frequency inverter unit, a DC-DC conversion unit, and a control unit. The AC-DC rectification and voltage stabilization unit has an input end, a first output end, and a second output end respectively connected with the three-phase winding coils, the DC-AC variable-frequency inverter unit, and the DC-DC conversion unit. The DC-DC conversion unit is configured to convert a DC power source rectified by the AC-DC rectification and stabilization unit to a plurality of DC power sources with different voltages to supply power to the control unit and directly output. The permanent magnet generator is smaller in volume and weight and lower in cost.

Abstract: Disclosed is a novel demulsifier, which is prepared by a method comprising the following steps of: dissolving a fatty alcohol polyether in a solvent to formulate a fatty alcohol polyether solution with a certain concentration; adding an organic catalyst and an olefin acid to the fatty alcohol polyether solution to carry out an esterification reaction for a certain period of time at a certain temperature and rotating speed; after the completion of the esterification reaction, adding an initiator to carry out a polymerization reaction for a certain period of time at a certain temperature and rotating speed; and after the completion of the polymerization reaction, evaporating the solvent in the reaction vessel with a rotary evaporator, and then placing the same in a vacuum drying oven and drying for a certain period of time to obtain the novel demulsifier.

Abstract: Provided are an OLED, display panel and display device. The OLED includes a first electrode, a second electrode, a light emitting layer and at least one blocking layer. The second electrode is arranged opposite to the first electrode. The light emitting layer is arranged between the first electrode and the second electrode. The blocking layer is arranged between the light emitting layer and the second electrode and/or between the light emitting layer and the first electrode. Each blocking layer of the at least one blocking layer comprises at least two blocking materials, electron mobility of at least one blocking material of the at least two blocking materials is lower than a first preset value, electron mobility of at least another blocking material of the at least two blocking materials is higher than a second preset value, and the first preset value is lower than the second preset value.

Abstract: Provided is an organic light-emitting diode. The organic light-emitting diode includes a first electrode, a second electrode, a light-emitting layer and a hole blocking layer, where the first electrode and the second electrode are oppositely disposed; the light-emitting layer is disposed between the first electrode and the second electrode; the hole blocking layer is disposed between the light-emitting layer and the second electrode; and the hole blocking layer includes at least two hole blocking sub-layers which are stacked, where a lowest unoccupied molecular orbital (LUMO) energy level decreases sequentially in the at least two hole blocking sub-layers.

Abstract: The present application provides an organic electroluminescent device and a display apparatus. The organic electroluminescent device includes a first conductive layer group, a second conductive layer group, and a light emitting layer disposed between the first conductive layer group and the second conductive layer group and in ohmic contact with the two groups. The first conductive layer group includes an electron blocking layer in ohmic contact with the light emitting layer, and a hole transport layer in ohmic contact with the electron blocking layer. The HOMO energy level of the electron blocking layer is between that of the hole transport layer and that of the light emitting layer, and the LUMO energy level of the electron blocking layer is shallower than that of the hole transport layer and that of the light emitting layer.

Abstract: A method for detecting an IPv6 aliased prefix based on fragmented fingerprint includes: generating a plurality of pseudo random addresses in a target prefix space; determining the target prefix as an active prefix; and determining that the plurality of the pseudo random addresses and the active prefix are configured on the same host, so as to identify the active prefix as the aliased prefix. This method may effectively discover a network host, reduce the cost of network detection, and provide more effective data support for network measurement, network surveying and mapping and security research.

Abstract: The present invention relates to a composition comprising: (a) a bis-(2-hydroxypropyl)-dimethylammonium methyl-sulphate fatty acid ester having an average chain length of the fatty acid moieties of from 12 to 30 carbon atoms; (b) a cationic poly saccharide; and (c) a nonionic polysaccharide. The present invention also relates to the method of use of the composition.

Abstract: A top emitting OLED device for improving viewing angle characteristics, comprising a substrate, a first electrode, a hole injection layer, a hole transport layer, a light-emitting layer, an electron transport layer, a second electrode and a light output coupling layer sequentially stacked on the substrate, wherein the second electrode has a light transmittance no less than 25%, and the hole injection layer has a refractive index no less than 1.8.

Abstract: Provided are a method and apparatus for determining pose information of a robot, a device and a medium. The method includes: fitting a target curve according to a motion trajectory of an image module relative to a target label when the robot rotates; determining a coordinate offset of the image module relative to a body of the robot according to the target curve, and determining a relative distance between the image module and the target label according to the image module; and determining the pose information of the robot according to the coordinate offset and the relative distance.