Abstract: Methods for preferentially and/or selectively detecting and/or quantitating target RNA, over DNA, in a biological or non-biological sample are described. The methods include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, the reaction mixture includes dNTPs, that include dITP. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the preferential and/or selective amplification and detection and/or quantitation of target RNA (over DNA), in the presence of dITP. The methods, kits, and reaction mixtures are for the preferential and/or selective detection and/or quantitation of RNA, over DNA, and are particularly useful with samples that comprise a number of different types of nucleic acids (e.g., DNA and RNA).

Abstract: A compound represented by general formula (I) or a pharmaceutically acceptable salt or a stereoisomer thereof, and a use thereof in treating diseases such as tumors, immunological diseases, and inflammatory diseases, as well as a pharmaceutical preparation and a pharmaceutical composition of the compound, and a use thereof.

Abstract: A method for indoor operation monitoring of a cleaning device is provided, which is executed by a server of a system for indoor operation monitoring of a cleaning device. The method includes generating a work region map; forming a monitoring map based on location fingerprints taken from a work region in the work region map; determining working trajectory points of the cleaning device based on a set of positioning data; obtaining a monitoring task region through a monitoring terminal; determining, based on the monitoring map, a monitoring region map corresponding to the monitoring task region, matching the working trajectory points with the monitoring region map, and determining cumulative trajectory points within the monitoring task region; and in response to determining that a count of the cumulative trajectory points and distribution situation of the cumulative trajectory points satisfy a preset update condition, sending a display update instruction to the monitoring terminal.

Abstract: Provided are an antibody targeting Claudin 18.2, an antibody-drug conjugate, and use thereof in treatment of cancer. Also provided are a nucleotide encoding the Claudin 18.2 antibody, a polynucleotide combination, an expression vector, an expression vector combination, a pharmaceutical composition comprising the Caudill 18.2 antibody and the antibody-drug conjugate, and an application thereof in preparation of a medication for treatment or prevention of cancer.

Abstract: A cup lid that enables single-handed operation, including a main lid body and an auxiliary lid body. The main lid body seals an opening of a container and has a circular recess, a water passing hole, an air vent, and at least one limiting flange. The auxiliary lid body is rotatably disposed on the circular recess and has at least one limiting groove, at least one cutaway portion, a water passing port, and an air guide slot in communication with the atmosphere. Each limiting flange enters a corresponding limiting groove via a corresponding cutaway portion and is slidably received therein. The water passing port opens and closes the water passing hole as the auxiliary lid body rotates, and the air vent is slidably received in the air guide slot.

Abstract: This invention involves immunizing mice with human ecto-5?-nucleotidase (CD73) to obtain multiple monoclonal antibodies whose heavy-chain and light-chain sequences are both novel amino acid sequences and which can be used to prepare CD73 enzyme activity inhibitors and anti-tumor drugs.

Abstract: Methods for the rapid detection of the presence or absence of Epstein Barr Virus (EBV) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting EBV, and kits are provided that are designed for the detection of target regions of EBV. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of EBV. Also described are primers and probes that detect different regions of EBV, and can be employed in a dual target assay for simultaneously detecting two different and non-overlapping target regions of EBV.

Abstract: A method for preparing nickel-magnesium loaded biochar-based bifunctional material is provided. The method includes: carbonizing a waste biomass material and washing it in a sulfuric acid solution, followed by deionized water washing, suction filtration, and drying to obtain a carbonized biochar; adding Ni(NO3)2·6H2O and Mg(NO3)2·6H2O to deionized water and stirring uniformly to obtain a loading solution; weighing the carbonized biochar according to a nickel loading amount of 20%-50% and adding to the loading solution and stirring to obtain a mixed solution, transferring the mixed solution to an oil bath for drying until water is completely evaporated; transferring a solid material to a crucible and roasting in the muffle furnace at 550° C.-650° C. under the nitrogen atmosphere for 1.5 h-2.5 h to obtain the nickel-magnesium loaded biochar-based bifunctional material.

Abstract: Provided is use of low-intensity pulsed ultrasound (LIPUS) in preparation of a product for treating dry age-related macular degeneration (dAMD), which belongs to the technical field of biomedicine. The present disclosure proposes for the first time that LIPUS can be used to treat the eye disease of dAMD. LIPUS allows for treating dAMD by transmitting acoustic energy to a target tissue. The LIPUS method provided by the present disclosure has the characteristics of non-invasiveness, painlessness, and no side effects.

Abstract: Disclosed is a torque sensing bionic clamping jaw. In the torque sensing bionic clamping jaw, a left clamping jaw skeleton is movably connected to a substrate, the left clamping jaw skeleton includes a first left groove and a second left groove which are in a side facing a right jaw, a left sensor quick-release connecting piece is detachably connected to the first left groove, a left torque measuring sensor is mounted on the left sensor quick-release connecting piece, a left flexible gasket quick-release connecting piece is detachably connected to the second left groove, and a left flexible gasket is mounted on the left flexible gasket quick-release connecting piece; a right torque measuring sensor is mounted on a right sensor quick-release connecting piece and opposite to the left torque measuring sensor, and a right flexible gasket is mounted on a right flexible gasket quick-release connecting piece.

Abstract: In various examples, a guidewire for temporary pacing of tissue includes an elongate core wire and a coil disposed along at least a portion of a length of the core wire. The coil is disposed radially outwardly from and around the core wire, wherein a core axis and a coil axis are substantially aligned. At least one electrode is disposed along the guidewire and includes an uninsulated portion of the core wire disposed within an electrode section of the coil. A spacing between adjacent windings of the electrode section of the coil is configured to allow a stimulation pulse to travel from the uninsulated portion of the core wire, through the spacing between the adjacent windings of the electrode section, and to the tissue in order to stimulate the tissue.

Abstract: A thermo container structure convenient to be stored, provides good thermal insulation effect and achieves stable support after being unfolded, including an outer container and an inner container; the outer container has a first body and a first cover; both filled with thermally insulated materials; the inner container has a second body and a second cover; the first body and the second body are both compressible and foldable structures, and the first body and the second body are foldable towards two different folding directions perpendicular to each other; in an unfolded state of the thermo container structure, the first cover can close against an opening of the first body, and the second cover can close against an opening of the second body.

Abstract: A cup lid that facilitates convenient operation by allowing effort saving opening of a water passing hole by using only one hand, wherein the cup lid has a main lid and an auxiliary lid; an upper surface of the main lid has the water passing hole and an air vent; the auxiliary lid is rotatably mounted on the upper surface of the main lid, and being axially limited with respect to the main lid. Rotation of the auxiliary lid will cause a water passing port disposed thereon to open or close the water passing hole; the auxiliary lid also has an air guide slot in which the air vent can slide therein when the auxiliary lid rotates, and the air guide slot is in communication with an external environment. A container using the cup lid is also provided.

Abstract: A display apparatus includes a cover plate and a display substrate. The cover plate includes a first base substrate, a black matrix and a support layer stacked on a side of the first base substrate, and a quantum dot layer disposed on the side of the first base substrate. The black matrix and the support layer each have a plurality of openings to form a plurality of opening regions. The quantum dot layer includes a plurality of quantum dot units. Each quantum dot unit is located in an opening region in the plurality of opening regions. The display substrate includes a second base substrate, driving circuit structures disposed on a side of the second base substrate, and light-emitting devices disposed on a side of the driving circuit structures. Each light-emitting device is coupled to a driving circuit structure in the driving circuit structures to emit light.

Abstract: A method and system for calculating main-loop parameters of an SLCC, and a readable medium.

Abstract: A method for indoor operation monitoring of a cleaning device is provided, which is executed by a server of a system for indoor operation monitoring of a cleaning device. The method includes generating a work region map; forming a monitoring map based on location fingerprints taken from a work region in the work region map; determining working trajectory points of the cleaning device based on a set of positioning data; obtaining a monitoring task region through a monitoring terminal; determining, based on the monitoring map, a monitoring region map corresponding to the monitoring task region, matching the working trajectory points with the monitoring region map, and determining cumulative trajectory points within the monitoring task region; and in response to determining that a count of the cumulative trajectory points and distribution situation of the cumulative trajectory points satisfy a preset update condition, sending a display update instruction to the monitoring terminal.

Abstract: In various examples, a guidewire for temporary pacing of tissue includes an elongate core wire and a coil disposed along at least a portion of a length of the core wire. The coil is disposed radially outwardly from and around the core wire, wherein a core axis and a coil axis are substantially aligned. At least one electrode is disposed along the guidewire and includes an uninsulated portion of the core wire disposed within an electrode section of the coil. A spacing between adjacent windings of the electrode section of the coil is configured to allow a stimulation pulse to travel from the uninsulated portion of the core wire, through the spacing between the adjacent windings of the electrode section, and to the tissue in order to stimulate the tissue.

Abstract: Provided are three-dimensional forming method and system. The method includes: controlling, by acoustic wave, bio-ink in acoustic resonant cavity to form cell cluster pattern M1; performing controllable photocuring on pre-curing position of the cell cluster pattern M1, to obtain cured formed structure; transferring the cured formed structure; controlling, by acoustic wave, the bio-ink in the acoustic resonant cavity to form cell cluster pattern M2, and adjusting the position, in the bio-ink, of the cured formed structure, such that the position is accurately joined with pre-curing position of the cell cluster pattern M2; performing controllable photocuring on the pre-curing position of the cell cluster pattern M2, to obtain cured formed structure; and circularly executing steps 3-5 a preset number of times, to obtain the three-dimensional tissue structure.