Patents by Inventor Ling Zhang

Ling Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TREATING ARTHRITIS BY USING STEM CELL PREPARATION AND METHOD FOR PREPARING STEM CELL PREPARATION
    Publication number: 20230201266
    Abstract: The present disclosure provides a method for treating arthritis by using a stem cell preparation. The stem cell preparation of the present disclosure can effectively delay cartilage degeneration caused by arthritis, and it is confirmed by whole blood analysis and blood biochemical analysis that the stem cell preparation in the form of three-dimensional stem cell spheres provides a safe treatment for arthritis. The present disclosure also provides a method for preparing the stem cell preparation.
    Type: Application
    Filed: September 9, 2021
    Publication date: June 29, 2023
    Inventors: Feng-Huei Lin, Che-Yung Kuan, Yu-Ying Lin, Ching-Yun Chen, Zhi-Yu Chen, I-Hsuan Yang, Ming-Hsi Chuang, Po-Cheng Lin, Chia-Hsin Lee, Kai-Ling Zhang, Pei-Syuan Chao, Wan-Sin Syu, Chun-Hung Chen, Ting-Ju Wang
  • Method and Apparatus for Antenna Calibration
    Publication number: 20230188225
    Abstract: Embodiments of the present disclosure provide methods and apparatus for antenna calibration. A method implemented at a network function comprises calibrating an antenna of the network function based on available time-frequency resources. The method further comprises communicating with at least one terminal device via the calibrated antenna.
    Type: Application
    Filed: June 24, 2020
    Publication date: June 15, 2023
    Inventors: Hao Zhang, Georgy Levin, Ling Zhang, Ang Feng
  • DOPAMINE D2 RECEPTOR LIGANDS
    Publication number: 20230143552
    Abstract: The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.
    Type: Application
    Filed: October 7, 2022
    Publication date: May 11, 2023
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Edward Scolnick, Michelle Palmer, Luka Dordevic, Michael C. Lewis, Jennifer Q. Pan, Yan-Ling Zhang, Qihong Xu
  • NEW POLYPEPTIDE COMPLEX
    Publication number: 20230120270
    Abstract: The present disclosure relates to a new polypeptide complex. Specifically, the present disclosure relates to a domain engineered antibody. At least one of the constant region domains CH1 and/or CL of the antibody is replaced, and the domain CH1/CL is replaced by a Titin T chain/Obscurin-O chain or by a Titin T chain/Obscurin-like-O chain.
    Type: Application
    Filed: January 8, 2021
    Publication date: April 20, 2023
    Inventors: Hua YING, Qiyue HU, Ling ZHANG, Langyong MAO, Jinping SHI, Tingting LI, Weiming LAI, Qianshan QIN, Xinsheng JIN, Weikang TAO
  • SARS-COV-2 SPIKE PROTEIN ANTIBODIES
    Publication number: 20230115257
    Abstract: Embodiments include monoclonal antibodies (mAbs) that recognize SARS-Cov-2 spike protein. The mAbs are capable of distinguishing among variants of the virus. The present disclosure also provides a composition and methods of making and using such a composition for treating, preventing, and/or detecting SARS-CoV-2 infection.
    Type: Application
    Filed: May 17, 2022
    Publication date: April 13, 2023
    Inventors: Brian A. ZABEL, Dan LUO, Ling ZHANG, Vydehi KANNEGANTI, Joyce YU, Sophie YANG, Lequn ZHAO, Hua TU, Xiaomei GE
  • Key-based cross domain registration and authorization
    Patent number: 11627132
    Abstract: The present invention generally relates to computer security, and more specifically, related to registration and authorization cross multiple domains. In an aspect, a computer-implemented method, computer-implemented system, and computer program product for cross domain registration by a source domain is provided. A request is sent by a source domain to register the source domain as a trusted domain of a target domain. An approval of the request is received by the source domain. The source domain issues a key to an application of the source domain for accessing the target domain.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: April 11, 2023
    Assignee: International Business Machines Corporation
    Inventor: Ling Zhang
  • Functionalized ethylene/alpha-olefin interpolymers with high graft levels
    Patent number: 11618818
    Abstract: A composition comprising an acid and/or anhydride grafted ethylene/alpha-olefin interpolymer that comprises the following properties: A) number of grafts per polymer chain?1.80, and B) melt viscosity (at 177° C.)?50,000 mPa·s.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: April 4, 2023
    Assignee: Dow Global Technologies LLC
    Inventors: Wanfu Ma, Santosh S. Bawiskar, Yi Jin, Ling Zhang-watson, Allan Walter Mclennaghan, Olaf Henschke
  • PAD-STEAM CATIONIZATION OF TEXTILES
    Publication number: 20230089849
    Abstract: Described are methods and systems for cationizing and dyeing a natural fiber-containing textile. The method includes a step of steam treating a textile padded with a base and cationizing agent in a defined temperature range (greater than 100° C. to less than 110° C.) and for a defined time period (1 min to 10 min). The cationizing agent in the presence of the base is capable of generating two epoxide groups. The cationization step in the presence of steam using the halogenated catonization agent of the invention facilitates improved dyeing.
    Type: Application
    Filed: February 2, 2021
    Publication date: March 23, 2023
    Inventors: Sandeep Nikam, Laura Havens, Ling Zhang-watson
  • SHARED CACHE FOR MULTIPLE INDEX SERVICES IN NONRELATIONAL DATABASES
    Publication number: 20230081324
    Abstract: A computer-implemented method includes receiving, by a processing unit, from a first tenant, a query to retrieve data from a nonrelational database system. The method further includes determining, by the processing unit, that an index associated with the query is cached in a shared index cache, wherein the shared index cache stores indexes for a plurality of tenants. The method further includes retrieving, by the processing unit, a result of the query based on the index in the shared index cache. The method further includes outputting, by the processing unit, the result of the query.
    Type: Application
    Filed: September 15, 2021
    Publication date: March 16, 2023
    Inventors: Peng Hui JIANG, Xing Xing SHEN, Guang Han SUI, Jun SU, Hai Ling ZHANG
  • BLACK PHOSPHORUS NANOSHEET, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
    Publication number: 20230075308
    Abstract: The present invention relates to a method of preparing a black phosphorus nanosheet and application, belonging to the technical field of functional material production. In the method, the black phosphorus sheet is used as the electrolytic anode, and an electrochemical reaction system is constructed together with an inert electrode and an alkaline aqueous electrolyte, wherein the alkaline aqueous electrolyte comprises an N-N dimethylformamide solution dissolved with epoxy resin. In alkaline aqueous electrolyte, the prepared black phosphorus nanosheet structure tends to be more stable, not easy to be damaged and the oxidation degree is reduced. Under alkaline conditions, it is conducive to improve the intercalation and stripping effect of black phosphorus material of anode and make the black phosphorus exfoliation more complete.
    Type: Application
    Filed: June 2, 2020
    Publication date: March 9, 2023
    Inventors: Jie CHEN, Yanhua LUO, Xiaodong PEI, Fan WANG, Fenglin TANG, Yefeng ZHU, Baojin SHEN, Xiuguang YANG, Ling ZHANG
  • PAD-DRY CATIONIZATION OF TEXTILES
    Publication number: 20230071562
    Abstract: Described are methods and systems for cationizing and dyeing a natural fiber-containing textile, which uses a mono- or di-quaternized cationizing agent. The method includes a step of heating the textile to a temperature in the range of 90° C. to less than 110° C. for a period of time in the range of 1 min to 10 min to react the cationizing agent with the textile. The cationization step in the presence of heat using the halogenated cationization agent of the invention facilitates improved dyeing.
    Type: Application
    Filed: February 2, 2021
    Publication date: March 9, 2023
    Inventors: Sandeep NIKAM, Laura HAVENS, Ling ZHANG-WATSON
  • Broadband panel array antenna
    Patent number: 11600930
    Abstract: A broadband panel array antenna includes a polarization layer, a radiating layer and a feed layer which are sequentially stacked from top to bottom. The feed layer is used for converting a single path of TE10 mode signals into a plurality of paths of same-power in-phase TE10 mode signals and transmitting the plurality of paths of TE10 mode signals to the radiating layer. The radiating layer is used for radiating the plurality of paths of TE10 mode signals from the feed layer to a free space. The polarization layer is used for rotating the polarization direction of an electric field generated by the radiating layer to reduce the side lobe in an E-plane direction diagram and an H-plane direction diagram. The broadband panel array antenna has the advantages of being low in side lobe, high in gain and efficiency, and low in machining cost.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: March 7, 2023
    Assignee: Ningbo University
    Inventors: Yang You, Jifu Huang, Ling Zhang, Qingchun You, Yunlong Lu
  • ALUMINUM ALLOY WITH PREFERRED MECHANICAL PROPERTY AND PREFERRED ELECTRICAL AND THERMAL CONDUCTIVITY AND RELATED MANUFACTURING METHOD
    Publication number: 20230054627
    Abstract: Aluminum alloy with preferred mechanical property and preferred electrical and thermal conductivity is provided by a manufacturing method. The aluminum alloy consists of Si about 0.33˜0.37 wt %, Mg about 0.45˜0.55 wt %, and Fe about 0.07˜0.15 wt %, and the rest weight of the aluminum alloy is Al. A ratio of Mg to a different between Al and one third Fe is ranged between 1.45˜1.75.
    Type: Application
    Filed: August 4, 2022
    Publication date: February 23, 2023
    Inventors: Ling ZHANG, Zhiming WANG, Ge QIN, Hongjiang MA, Li HAN, Yongchang LIU, Sujing GE, Fangfang SUN, Haijun YANG
  • CORONA-RESISTANT ENAMELED ROUND WIRE AND PREPARATION METHOD THEREFOR
    Publication number: 20230047864
    Abstract: Disclosed are a corona-resistant enameled round wire and preparation method therefor. The corona-resistant enameled round wire is suitable for electric vehicle motors and comprises a copper conductor and an insulating layer, wherein the insulating layer clads the copper conductor and comprises, in sequence from inside to outside, a corona-resistant polyamideimide coating, a corona-resistant special resin coating, a corona-resistant polyimide coating, a corona-resistant modified silicone resin coating, and a corona-resistant polyamideimide coating.
    Type: Application
    Filed: August 11, 2022
    Publication date: February 16, 2023
    Inventors: Ling ZHANG, Xingwu DAI, Yanjun CAI, Ge QIN, Lu BI, Yu XIA, Cheng ZHOU, Guo LI, Qingquan LEI
  • LAPTOP STAND
    Publication number: 20230052344
    Abstract: A multifunctional computer stand, including a symmetrically arranged push shaft, outer wall of the push shaft is movably connected with a connecting rod, and the left and right sides of push shaft are respectively connected with a first and a second rotating rod. Outer wall of connecting rod is rotatably connected with a plurality of geared fixing seats, right side of second rotating rod is provided with a plurality of limit rings, and buttons are slidably connected in limit rings. A first button and a second button are provided with a gear shaft on the lower side, a spring is fixed on the bottom surface of the gear shaft, and the other end of the spring is fixedly connected with the end surface of the connecting rod so the inner walls of the first and the second rotating rod are provided with limit teeth that mesh with the gear shaft.
    Type: Application
    Filed: August 13, 2021
    Publication date: February 16, 2023
    Inventor: Ling Zhang
  • Inhibitors of histone deacetylase
    Patent number: 11572368
    Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R2a, R2b, R2c, R5 and t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: February 7, 2023
    Assignees: The General Hospital Corporation, The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Li-Huei Tsai, Stephen J. Haggarty, Yan-Ling Zhang
  • ANTI-CEA ANTIBODY AND APPLICATION THEREOF
    Publication number: 20230013784
    Abstract: Provided is an anti-CEA antibody comprising a heavy chain variable region and a light chain variable region, a drug conjugate thereof, and a composition containing the anti-CEA antibody or the drug conjugate thereof, and an application thereof as a drug.
    Type: Application
    Filed: June 24, 2020
    Publication date: January 19, 2023
    Inventors: Hua YING, Langyong MAO, Ling ZHANG, Hu GE, Weikang TAO
  • Sparse information sharing system
    Patent number: 11558448
    Abstract: In an approach for a sparse information sharing system, a processor receives a request from a host owner for a host to become a server of an information sharing system, wherein the request specifies at least one type of information the server will maintain and provide to visitors of the server. A processor syncs the server with other servers of the information sharing system with information of the specified at least one type of information. A processor, responsive to the server receiving updated information from a visitor of the server, notifies the other servers of the updated information.
    Type: Grant
    Filed: September 22, 2021
    Date of Patent: January 17, 2023
    Assignee: International Business Machines Corporation
    Inventors: Guang Han Sui, Peng Hui Jiang, Xing Xing Shen, Jun Su, Hai Ling Zhang
  • Adhesive Composition
    Publication number: 20230002599
    Abstract: The present disclosure provides a composition. In an embodiment a composition is provided and includes: (A) an ethylene-based interpolymer having the following: (i) a density from 0.860 g/cc to 0.900 g/cc; and (ii) a melt viscosity, at 177° C., less than, or equal to, 50,000 mPa·s; and (B) a rosin ester containing the following: (i) greater than, or equal to, 75 mol % aliphatic carbon, based on total moles of carbon in the rosin ester; and (ii) less than, or equal to, 3.0 mol % ester group carbon, based on total moles of carbon in the rosin ester.
    Type: Application
    Filed: September 14, 2022
    Publication date: January 5, 2023
    Inventors: Wanfu Ma, Ling Zhang-Watson
  • Choking rescue device
    Patent number: D982736
    Type: Grant
    Filed: December 29, 2022
    Date of Patent: April 4, 2023
    Inventors: Liang Lv, JiGuang Zhang, ZhengHao Ye, LianBo Zhao, Ling Zhang