Abstract: Disclosed are a corona-resistant enameled round wire and preparation method therefor. The corona-resistant enameled round wire is suitable for electric vehicle motors and comprises a copper conductor and an insulating layer, wherein the insulating layer clads the copper conductor and comprises, in sequence from inside to outside, a corona-resistant polyamideimide coating, a corona-resistant special resin coating, a corona-resistant polyimide coating, a corona-resistant modified silicone resin coating, and a corona-resistant polyamideimide coating.

Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R2a, R2b, R2c, R5 and t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.

Abstract: Provided is an anti-CEA antibody comprising a heavy chain variable region and a light chain variable region, a drug conjugate thereof, and a composition containing the anti-CEA antibody or the drug conjugate thereof, and an application thereof as a drug.

Abstract: In an approach for a sparse information sharing system, a processor receives a request from a host owner for a host to become a server of an information sharing system, wherein the request specifies at least one type of information the server will maintain and provide to visitors of the server. A processor syncs the server with other servers of the information sharing system with information of the specified at least one type of information. A processor, responsive to the server receiving updated information from a visitor of the server, notifies the other servers of the updated information.

Abstract: The present disclosure provides a composition. In an embodiment a composition is provided and includes: (A) an ethylene-based interpolymer having the following: (i) a density from 0.860 g/cc to 0.900 g/cc; and (ii) a melt viscosity, at 177° C., less than, or equal to, 50,000 mPa·s; and (B) a rosin ester containing the following: (i) greater than, or equal to, 75 mol % aliphatic carbon, based on total moles of carbon in the rosin ester; and (ii) less than, or equal to, 3.0 mol % ester group carbon, based on total moles of carbon in the rosin ester.

Abstract: The present disclosure provides antibodies that bind to the SARS-CoV-2 spike protein, as well as compositions containing the same, and methods of making and using such a composition for treating, preventing, and/or detecting SARS-CoV-2 infection.

Abstract: An inorganic solid-state electrochromic module containing an inorganic transparent conductive film, including a transparent substrate and a first transparent conductive layer, a first transparent metal layer, a first transparent protective layer, an inorganic electrochromic layer, an inorganic ion conductive layer, an inorganic ion storage layer, a second transparent metal layer, a second transparent protective layer, a second transparent conductive layer, a encapsulating film and a transparent front plate successively formed on the transparent substrate.

Abstract: The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.

Abstract: The present disclosure provides a system for perceiving an operating state of a large power transformer based on vibro-acoustic integration, including a perception layer, a network layer, and a diagnostic layer, where the perception layer is used for monitoring, in real time, a state parameter for a coupling vibration signal and an acoustic signal of each of a transformer core, a winding, a clamp and a housing, a state parameter of each of a vibration signal and an acoustic signal during a gear position change of an on-load tap changer (OLTC), and preliminarily diagnosing and analyzing monitored data. The system can monitor the operating state of the OLTC online for a long time, flexibly configure the sensor channel and the sensor type according to different application requirements, automatically acquire and identify the gear position change, and correctly identify and process a gear position corresponding to the monitoring signal.

Abstract: A mechanical structure for installing cover plates of a pasta machine includes at least two brackets arranged symmetrically; a plurality of cover plates arranged between the two brackets, two ends of each cover plate are respectively and detachably connected to the two brackets. The cover plates are integrally formed by sheet metal technology. The cover plates are connected/mounted to brackets respectively through a snap-on and/or a slide-on connection.

Abstract: A Pancreatic Ductal Adenocarcinoma (PDAC) image segmentation method, an electronic device, and a storage medium are provided. In the PDAC image segmentation method, a first model is trained using a first data set; and a second model is trained using a second data set. A third data set is obtained by annotating a to-be-annotated data set using the first model and the second model and a third model is trained using a fourth data set. A training set is obtained by modifying the first data set and the third data set using the third model and a segmentation model is obtained by training an nnUNet using the training set. A to-be-segmented PDAC image is input into the segmentation model, and a segmentation result is obtained. By utilizing the PDAC image segmentation method, a more accurate PDAC image segmentation is achieved.

Abstract: A method for enzymatic preparation of fludarabine phosphate, comprising reaction of fludarabine with a high-energy phosphate compound under the action of deoxyribonucleic acid kinase. According to said method, acetate kinase and acetyl phosphate free acid or acetyl phosphate are also added. The technical problems present in the existing processes are successfully addressed by employing the enzymatic process to prepare the fludarabine phosphate. The usage of the high-energy phosphate compound is reduced by means of adding acetate kinase to recycle and regenerate a small amount of the high-energy phosphate compound, thereby reducing the generation of by-products having similar structures to the fludarabine phosphate, enhancing the operation convenience of purification steps in the industrial production of the fludarabine phosphate. The process is environment friendly, the reaction conditions are moderate, the cost is low, and the yield and the purity of the product obtained are high.

Abstract: The present disclosure relates to a CD3 antibody and a pharmaceutical use thereof. Specifically, the present disclosure relates to forming a multi-specificity antibody by using CD3 antibody and binding molecules of another target. The multi-specificity antibody may simultaneously bind to CD3 and another tumor-associated antigen, and bind and activate CD3-positive T cells while binding tumor-associated antigen-expressing cells, thereby promoting T cells specifically killing tumor cells that express tumor-associated antigens. In addition, the present disclosure also provides a preparation and application of a multi-specific antibody.

Abstract: A preoperative survival prediction method and a computing device applying the method include constructing a data seta according to a plurality of enhanced medical images and a resection margin of each enhanced medical image and obtaining a plurality of training data sets from the constructed data set. For each training data set, multi-task prediction models are trained. A target multi-task prediction model is selected from the plurality, and a resection margin prediction value and a survival risk prediction value are obtained by predicting an enhanced medical image to be measured through the target multi-task prediction model. The multi-task prediction model more effectively captures the changes over time of the tumor in multiple stages, so as to enable a joint prediction of a resection margin prediction value and a survival risk prediction value.

Abstract: Provided are a data transmission control method and device and a non-transitory computer-readable medium. The data transmission control method includes: determining a multiple and a remainder according to a total data size of to-be-transmitted data and a set byte size, where the multiple is equal to a quotient obtained by dividing the total data size by the set byte size, and the remainder is equal to a remainder obtained by dividing the total data size by the set byte size; sequentially transmitting data whose size is the set byte size multiplied by the multiple in the to-be-transmitted data by transmitting data of the set byte size each time; and in response to the remainder being not zero, transmitting remaining data whose size is the remainder in the to-be-transmitted data.

Abstract: A low-sidelobe plate array antenna includes a radiation layer and a feed layer. The radiation layer is superimposed on the feed layer and includes a first plate and a radiation array disposed on the first plate. The radiation array is formed by n2 radiation units which are distributed in 2(k-1) rows and 2(k-1) columns. Each radiation unit in the radiation layer is constituted by two first radiation assemblies and two second radiation assemblies. Each first radiation assembly comprises a first rectangular bar, a first rectangular cavity, a second rectangular cavity and a third rectangular cavity. The first rectangular cavity, the second rectangular cavity and the third rectangular cavity in the first radiation assembly are stacked in presence of an azimuth deviation to form a three-layer coupled structure, and the first rectangular bar located in the first rectangular cavity can better restrain cross polarization and reduce the sidelobe.

Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein X1, X2, X3, X4, X5, W1, W2, W3, and W4 are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. In one aspect, the invention relates to selective HDAC3 inhibitors useful for protecting ?-cells and improving insulin resistance. The selective HDAC3 inhibitors are also useful for promoting cognitive function and enhancing learning and memory formation.

Abstract: A kit of a scooter and a scooter are provided. The kit includes: a deck assembly; a first steering assembly arranged to a first end of the deck assembly; a driven wheel assembly arranged to the first steering assembly and configured to rotate relative to the deck assembly through the first steering assembly; a second steering assembly arranged to a second end of the deck assembly; a connecting device arranged to the second steering assembly and configured to rotate relative to the deck assembly through the second steering assembly. The connecting device is a device of the kit configured to be connected to a power wheel assembly.

Abstract: An electric scooter includes a deck, a power wheel unit, a power wheel steering unit, a driven wheel, a driven wheel steering unit, a power supply unit and a whole scooter controller. The power wheel unit includes a driving wheel; the power wheel steering unit is arranged between the deck and the power wheel unit; the driven wheel is spaced apart from the power wheel unit; the driven wheel steering unit is arranged between the driven wheel and the deck; the power supply unit is electrically coupled to the power wheel unit; the whole scooter controller is in communication with the power wheel unit and controls rotation of the driving wheel.

Abstract: A method for pancreatic mass diagnosis and patient management includes: receiving CT images of a pancreas of a patient, the pancreas of the patient including a mass; performing a segmentation process on the CT images of the pancreas and the mass to obtain a segmentation mask of the pancreas and the mass of the patient; performing a mask-to-mesh process on the segmentation mask of the pancreas and the mass of the patient to obtain a mesh model of the pancreas and the mass of the patient; performing a classification process on the mesh model of the pancreas and the mass of the patient to identify a type and a grade of a segmented pancreatic mass; and outputting updated CT images of the pancreas of the patient, the updated CT images including the segmented pancreatic mass highlighted thereon and the type and the grade of the segmented pancreatic mass annotated thereon.