Abstract: Aspects of the present disclosure are directed to synthetic DNA binding peptides, as well as methods of generating such peptides and methods for use of such peptides in, for example, DNA binding, modifying gene expression, and treatment of various conditions such as cancer, fibrosis, and diabetes. Certain aspects provide synthetic DNA binding dimers comprising two modified bZIP peptides, each comprising a modified basic domain and a modified leucine zipper domain and linked via an interpeptide linker (e.g., a side-by-side interpeptide linker). Also disclosed are universal methods for generating high affinity synthetic DNA binding dimers from any bZIP protein.

Abstract: Certain aspects of the present disclosure provide techniques for converting a bridged token on a blockchain to a native token on the blockchain. An example method generally includes pausing a token bridge between a first blockchain and a second blockchain. Minting privileges on the second blockchain are adjusted such that a designated user is granted privileges to control token minting on the second blockchain and no other users are allowed to control token minting on the second blockchain. It is validated that a quantity of a bridged token has remained unchanged since a freeze time at which the token bridge was paused. Based on validating that the quantity of the bridged token has remained unchanged since the freeze time, the bridged token is converted to a native token existing on the second blockchain.

Abstract: A computer implemented method includes creating a cache within system management memory to cache data from a firmware flash memory to allow access to the cache by system firmware, providing a baseboard management controller ownership of the firmware flash memory in a server, updating the firmware in the firmware flash memory via the baseboard management controller, relinquishing baseboard management controller ownership of firmware flash memory upon completion of updating the firmware, and flushing the cache back to the firmware flash memory in response to baseboard management controller relinquishing ownership of the firmware flash memory.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: Disclosed are plant growth promotors of general formula (I).

Abstract: Systems and methods are provided for dual duplex Belly-to-Belly Little Connector (BBLC) based optical connectors.

Abstract: A computing system that enables data stored in a persistent memory region to be preserved when a processor fails can include volatile memory comprising the persistent memory region, non-volatile memory, and a system on a chip (SoC). The SoC can include a main processor that is communicatively coupled to both the volatile memory and the non-volatile memory. The SoC can also include an auxiliary processor that is communicatively coupled to both the volatile memory and the non-volatile memory. The SoC can also include instructions that are executable by the auxiliary processor to cause the data in the persistent memory region of the volatile memory to be transferred to the non-volatile memory in response to a failure of the main processor.

Abstract: The use of a compound of the general formula (I) with the following definitions: R1 hydrogen, OH, NH2, C1-30-hydrocarbon residue which can contain one to three halogen atoms and/or one to six heteroatoms, selected from the group consisting of nitrogen, oxygen and sulfur, R2, R3 independently hydrogen, C1-12-hydrocarbon residue which can contain one or two halogen atoms and/or one to three heteroatoms, selected from the group consisting of nitrogen, oxygen and sulfur, it also being possible for R2 and R3 to be covalently linked to form a 5- to 8-membered heterocyclic ring, which can contain 1 or 2 halogen atoms and/or one to three further heteroatoms in addition to the heteroatoms N and O already part of the heterocyclic ring, R4 independently hydrogen, halogen, NO2, C1-12-hydrocarbon residue which can contain one or two halogen atoms and/or one to three heteroatoms, selected from the group consisting of nitrogen, oxygen and sulfur, n 0; 1; 2 or 3, 86 as plant growth promotor.

Abstract: A computer implemented method includes creating a cache within system management memory to cache data from a firmware flash memory to allow access to the cache by system firmware, providing a baseboard management controller ownership of the firmware flash memory in a server, updating the firmware in the firmware flash memory via the baseboard management controller, relinquishing baseboard management controller ownership of firmware flash memory upon completion of updating the firmware, and flushing the cache back to the firmware flash memory in response to baseboard management controller relinquishing ownership of the firmware flash memory.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: A messaging apparatus for sending a multimedia message includes a processor and a memory coupled to the processor and including instructions stored thereon. The instructions, when executed by the processor, cause the messaging apparatus to send display a list of multimedia contents on a screen based on a search term, receive a user's selection of one of displayed multimedia contents, obtain text content corresponding to the selected multimedia content, receive a user's selection of a graphical representation of the user's emotion, combine, in order, the selected multimedia content, as a first layer, the selected graphical representation of the user's emotion, as a second layer, and the text content, as a third layer, to generate a flattened multimedia message, and send the flattened multimedia message via a messaging application.

Abstract: A computing system that enables data stored in a persistent memory region to be preserved when a processor fails can include volatile memory comprising the persistent memory region, non-volatile memory, and a system on a chip (SoC). The SoC can include a main processor that is communicatively coupled to both the volatile memory and the non-volatile memory. The SoC can also include an auxiliary processor that is communicatively coupled to both the volatile memory and the non-volatile memory. The SoC can also include instructions that are executable by the auxiliary processor to cause the data in the persistent memory region of the volatile memory to be transferred to the non-volatile memory in response to a failure of the main processor.

Abstract: A medical scope device such as an endoscope is produced using a cast aluminum process including a molten casting aluminum alloy including a maximum of 0.2-0.3% Si and at least 5% Zn. The process includes providing an investment casting mold, casting the aluminum alloy in the mold to create a component and removing the mold from the component, post-machining the component to meet a desired specification, and after post-machining the component, performing surface finishing, such as centrifugal barrel finishing (CBF) sufficient to remove impurities on casting surfaces by 2-3 mils, then coating the component with a micro-crystalline aluminum anodic coating of at least 0.5 mil thickness. A medical scope and product-by-process is also provided employing such techniques.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: Systems and methods are disclosed to implement an indexing engine that maintains an index in an index store for a storage object in a data store. In embodiments, the index store may be implemented using an in-memory storage cluster separate from the data store. The storage object may have multiple indexes, which may have different filtering or sorting criteria for the data. In embodiments, updates to the storage object are received as an update stream by the indexing engine. Based on configurable indexing rules, the indexing engine applies the updates to the appropriate indexes. To service a query to the data store, a query engine first retrieves a set of keys satisfying the query from the index store, and then data corresponding to the keys from the data store or another index. In embodiments, the index may be refreshed via touch updates of selected data in the storage object.

Abstract: Network access is provided to a networking device. In one approach, a method includes: obtaining, by a gateway, access rules for a networking device; providing, by the gateway, one or more dedicated networking tunnels between the gateway and respective remote gateways to one or more respective network segments, wherein the networking device is authorized to access the one or more network segments by the access rules; and routing, by the gateway, networking packets from the networking device based on source address information in the networking packets to the one or more dedicated networking tunnels, and based on destination address information in the networking packets, routing the networking packets to a selection of the one or more dedicated networking tunnels.

Abstract: A medical scope device such as an endoscope is produced using a cast aluminum process including a molten casting aluminum alloy including a maximum of 0.2-0.3% Si and at least 5% Zn. The process includes providing an investment casting mold, casting the aluminum alloy in the mold to create a component and removing the mold from the component, post-machining the component to meet a desired specification, and after post-machining the component, performing surface finishing, such as centrifugal barrel finishing (CBF) sufficient to remove impurities on casting surfaces by 2-3 mils, then coating the component with a micro-crystalline aluminum anodic coating of at least 0.5 mil thickness. A medical scope and product-by-process is also provided employing such techniques.

Abstract: The invention provides a method for automatically analyzing and filtering redundant alarms in radio transceiver systems consisting of the following steps: step 1: the operator shall define the relationship between the alarms, defining rules to filter redundant alarms at the FRDU block; step 2: the FSU block will detect the alarm and send it to the FAFU block; step 3: FAFU block will receive alarms from FSU, based on the rules defined in FRDU block will analyze and filter out redundant alarms; Step 4: The FSMU block will receive the alarms after being filtered, stored in the database and also send these alarms to the EMS system.

Abstract: This disclosure relates to refiner plate segments having feeding grooves having a first width at a first end of the feeding groove, wherein the first end of the feeding groove is disposed closer to an inner diameter of the refiner plate segment, and a second end of the feeding groove having a second width, wherein the second end of the feeding groove is disposed closer to the outer diameter than the first end and wherein the second width is less than the first width. It is believed that the increased width of the feeding groove at the inner diameter, coupled with the change in angle or curve of the feed groove from a feeding angle to a holding angle such that the centrifugal force applied to the lignocellulosic material surpasses the plugging force, allows for improved hydraulic capacity over the refiner plate segment without reducing refining efficiency.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.