Abstract: The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof.

Abstract: Aspects relate to a priority mechanism for prioritizing network identifiers, for example SSIDs. As described herein, a UE may obtain one or more network identifier sets, each of the one or more network identifier sets having one or more network identifiers for a first RAT and a priority level, determine one or more of the network identifier sets that are under control of a second RAT, and after the determining, manage connections to the first RAT based, at least in part, on the priority level of the network identifier sets.

Abstract: A UE may receive, via a first communication link that uses a first radio access technology (RAT), information that identifies a threshold associated with a second communication link that uses a second RAT. The UE may monitor one or more communications on the second communication link. The UE may determine whether a parameter associated with the second communication link satisfies the threshold based at least in part on monitoring the one or more communications on the second communication link. The UE may provide a message via the first communication link when the parameter associated with the second communication link satisfies the threshold.

Abstract: Systems and methods provided herein. In one embodiment, a system includes an advisory system including a loss computation engine configured to derive a total system loss for an industrial plant based on a first sensor positioned in a first industrial plant component and on a first physical model of the first industrial plant component. The advisory system further includes a cost model configured to use a cost function to derive a cost based on the total system loss, and a control strategy system configured to derive an advisory report, a control correction factor, or a combination thereof, based on the cost, wherein a control system is configured to apply the control correction factor to control a process in the industrial plant.

Abstract: Systems and methods are described that configure network devices to dynamically (1) download privilege setting definitions from an authentication server to address a currently connected set of client devices associated with these privilege setting definitions and (2) clear privilege setting definitions that are no longer in use by client devices connected to the network device. In particular, a network device may determine if a privilege setting definition associated with a successfully authenticated client device is locally available on the network device and request the privilege setting definition from the authentication server when not locally available. In some situations, the authentication server may selectively transmit update messages to network devices that may be affected by an update to a privilege setting definition such that the network devices may request this updated privilege setting definition for download.

Abstract: A method for controlling and enhancing a startup operation for a combined cycle power block (block) having at least one gas turbine and at least one steam turbine, wherein operating parameters define performance and operational characteristics for the startup operation, the method comprising: receiving measured operating parameters from a plurality of reference blocks and, for each of the plurality of reference blocks, a plurality of types of the startup operations; given the measured operating parameters, developing one or more reference transfer functions between two of the measured operating parameters; receiving measured operating parameters from the startup operation of a target block; given the measured operating parameters from the target block, developing one or more transfer functions for the target block between two of the operating parameters; selecting one of the reference transfer functions; and normalizing the transfer function of the target block per the selected reference transfer function.

Abstract: A multi-layered, web-shaped filter material for a filter element may include a fleece layer, a cellulose layer, and a nanofibre layer arranged between the fleece layer and the cellulose layer. The nanofibre layer may have, in a thickness direction, at least one of an increasing fibre thickness and an increasing fibre density. The cellulose layer may have an impregnation at least on a side facing the nanofibre layer.

Abstract: A method for optimizing a fleet of generating assets in which groupings include remotely located power blocks that operate so to collectively generate a fleet output level. The method may include: receiving real-time and historical measured values of operating parameters; for each of the generating assets, deriving a relational expression between the measured values of the process inputs and the measured values of the process outputs; defining a selected operating period; selecting competing operating modes for the fleet; based on the relational expressions and a generating configuration of the competing operating modes, calculating a result set for the operation of the fleet proposed during the selected operating period; defining a cost function; and evaluating each of the result sets pursuant to the cost function and, based thereupon, designating one of the competing operating modes as an optimized operating mode.

Abstract: A combined cycle power plant system that includes: a gas turbine operably connected to a heat recovery steam generator; a first controller for optimizing a shutdown operation defined between an initiating shutdown command and a terminating event, wherein the first is controller configured to execute the steps of: receiving the shutdown initiating command; receiving operating parameters measured by sensors for each of a first component and a second component of the combined cycle power plant, and, based thereupon, determining a current state for each of the first and the second component; based on the current state, deriving an optimized shutdown operating mode for transitioning the first component and the second component from the current state to a shutdown state.

Abstract: A method, a master database node and a subscriber database node for optimizing index. The method for optimizing index includes: checking, by a master database node, if role information of an index matches role information of the master database node, when the index is added into the master database node; updating database information by using the index when the role information of the index matches the role information of the master database node. In this invention, unnecessary indexes in the master database node and the subscriber database node are reduced while keeping the schema the same. Furthermore, unnecessary logs transmitted from the master database node to the subscriber database node are reduced.

Abstract: A method for optimizing a generation of an output level over a selected operating period by a power block, wherein the power block comprises multiple gas turbines for collectively generating the output level. The control method may include: receiving current state data regarding measured operating parameters for each of the gas turbines of the power block; based on the current state data, defining competing operating modes for the power block; based on each of the competing operating modes, deriving a predicted value for a performance parameter regarding the operation of the power block over the selected operating period; determining a cost function and, pursuant thereto, evaluating the operation of the power block based on the predicted value of the performance parameter so to determine a projected cost; and comparing the projected costs from each of the optimized operating modes so to select therefrom an optimized operating mode.

Abstract: The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE?/?) mice along with the endothelial cell age-delaying effects of Mito-Esc.

Abstract: Systems and methods provided herein output an operational advisory based upon a plurality of models derived from a plurality of data, in which the plurality of models comprise at least one of a plant transfer function, a degradation contributor model, or a plant level cost model, and in which the plurality of data is derived from at least one of current plant data, historical plant data, business data, environmental data, component data, degradation contribution data, an optimization goal, or a combination thereof.

Abstract: A multi-layered, web-shaped filter material for a filter element may include a fleece layer, a cellulose layer, and a nanofibre layer arranged between the fleece layer and the cellulose layer. The nanofibre layer may be a coating of a nanofibre material disposed on the fleece layer. The cellulose layer may have an impregnation at least on a side facing the nanofibre layer.

Abstract: The present application discloses new taxane analogs, intermediates and methods for producing them. The present application is also directed to pharmaceutical formulations comprising abeo-taxanes and methods of treating cancer with the abeo-taxanes.

Abstract: Methods and systems are provided for global server load balancing in a communication network using a global site selector and an application control engine in communication with the global site selector, in which the application control engine notifies the global site selector in response to a state change for a virtual internet protocol (VIP) address. Keepalive methods generally rely on periodically polling VIP addresses to check whether they are in an ONLINE or OFFLINE state. A minimum interval between two keepalives can be as long as 40 seconds, during which, without a mechanism to reflect state change to the load balancer in real time, if a VIP address changes state (e.g., VIP address failure), a customer can experience network outage during the time interval. Embodiments provide a mechanism to reflect, in real time, the current VIP address state to a global server load balancer to reduce failure detection time.

Abstract: The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof.

Abstract: A bed comprises a fixed width deck section, a wing movably coupled to the fixed width section, and a rack and pinion mechanism for extending and retracting the wing.

Abstract: An integrated microwave transistor amplifier includes a AlGaN/GaN active transistor arrangement on a thinned Si 1-mil heat spreader. Elongated, plated-through vias extend from the source portions of the transistor arrangement through the spreader to a thick gold supporting layer. A matching circuit is defined on a four-mil GaAs substrate, also with a thick gold support layer. A stepped heat sink supports the matching circuit and the active transistor with surfaces coplanar. Bond wires interconnect the matching circuit with the gate or drain connections of the transistor.

Abstract: Devices, methods, and systems for determining pushback direction are described herein. One method includes receiving a video image of an aircraft during a pushback of the aircraft, determining a motion flow map associated with the video image during the pushback, determining a motion orientation histogram associated with the video image during the pushback, and determining a direction of the pushback based on the motion flow map and the motion orientation histogram.