Abstract: The present invention provides a stable oral liquid solution composition comprising ivacaftor or a pharmaceutically acceptable salt or solvate thereof and a solvent system selected from the group consisting of Polyethylene Glycols 400 and/or Hydrogenated Vegetable Oil used individually or in combination thereof. The invention also provides a method for treating or lessening the severity of cystic fibrosis is provided.

Abstract: A device including a first magnetic layer, a templating structure and a second magnetic layer is described. The templating structure is on the first magnetic layer. The second magnetic layer is on the templating structure. The templating structure includes D and E. A ratio of D to E is represented by D1-xEx, with x being at least 0.4 and not more than 0.6. E includes a main constituent. The main constituent includes at least one of Al, Ga, and Ge. E includes at least fifty atomic percent of the main constituent. D includes at least one constituent that includes Ir. D includes at least 50 atomic percent of the at least one constituent. The templating structure is nonmagnetic at room temperature. At least one of the first magnetic layer and the second magnetic layer includes at least one of a Heusler compound and an L10 compound.

Abstract: Embodiments include apparatuses, methods, and systems for managing a data warehouse associated with an electronic payment transaction processing network. A first set of stores are active and a second set of stores are inactive in an offer program related to merchandise of a merchant. A first set of transaction records for a first set of transactions from the first set of stores and a second set of transaction records for a second set of transactions from the second set of stores are obtained. A first set of operations on the data warehouse for the first set of transaction records and a second set of operations on the data warehouse for the second set of transaction records may be performed. The second set of operations, different from the first set of operations, includes an update operation on the data warehouse. Other embodiments may also be described and claimed.

Abstract: Aspects of the present disclosure provide systems, methods, apparatus, and computer-readable storage media that support relevance-based analysis and filtering of documents and media for one or more enterprises. Aspects disclosed herein leverage custom-built taxonomies, natural language processing (NLP), and machine learning (ML) for identifying and extracting features from highly-relevant documents. The extracted features are vectorized and then filtered based on entities (e.g., enterprises, organizations, individuals, etc.) and compliance-based risks (e.g., illegal or non-compliant activities) that are highly relevant to a particular client. The filtered feature vectors are used to identify and highlight relevant information in the corresponding documents, enabling decision making to resolve compliance-related risks. The aspects described herein generate fewer false positive or otherwise less relevant results than conventional document screening applications or manual techniques.

Abstract: The present disclosure is drawn to compositions and methods for treating CNS disorders. In one embodiment, an oral pharmaceutical composition can comprise a therapeutically effective amount of pregn-4-ene-3,20-dione; and a pharmaceutically acceptable carrier that provides formation of either 3?-OH-5?-pregnan-20-one, or 3?-OH-5?-pregnan-20-one, or both in an amount sufficient to treat a CNS disorder when orally administered to a subject. In another embodiment, a method of treating a CNS disorder can comprise orally administering to a subject, a therapeutically effective amount of pregn-4-ene-3,20-dione that provides an amount of GABA receptor binding pregn-4-ene-3,20-dione metabolites that is sufficient to treat the CNS disorder.

Abstract: Provided are a method and an apparatus for determining an optimal rotation angle during compression of a spherical multimedia content where the processor may receive first multimedia content corresponding to the spherical multimedia content, generate a plurality of second multimedia contents based on the first multimedia content by rotating the first multimedia content to a plurality of rotation angles, perform an edge analysis on each of the plurality of the second multimedia contents, identify the number of edges aligned to one of a vertical axis or a horizontal axis based on the edge analysis, select second multimedia content with the maximum number of edges, and determine an optimal rotation angle.

Abstract: A device provisioning service provisions a network-connected device to access one or more service systems using a supplemental cryptographic identity of the network-connected device. An initial enrollment record (associated with an initial cryptographic identity) and a supplemental enrollment record are stored in a device provisioning service. An identity issuance request is received from the network-connected device at the device provisioning service. The identity issuance request includes the initial cryptographic identity. The supplemental cryptographic identity is requested from a supplemental cryptographic identity issuer identified in the initial enrollment record based on the identity issuance request. The requested supplemental cryptographic identity is received at the device provisioning service from the supplemental cryptographic identity issuer. The network-connected device is provisioned to access the one or more service systems according to the supplemental enrollment record.

Abstract: A system and method for reliable control of a high rotor pole switched reluctance machine (HRSRM) utilizing a sensorless reliable control system. The method comprising: energizing at least one of the plurality of stator phases; measuring a first current value and time taken by the first current value to reach a first peak value or preset threshold value of current; determining a self-inductance value; measuring a second current value and time taken by an adjacent un-energized stator phase to reach a second peak value of current; determining a mutual inductance value; and estimating a rotor position utilizing the self-inductance and mutual inductance values; and controlling the HRSRM based on the estimated rotor position.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for reclaiming one or more portions of storage resources in a computer system serving one or more virtual computing instances, where the storage resources in the computer system are organized in clusters of storage blocks. In one aspect, a method includes maintaining a respective block tracking value for each storage block that indicates whether a call to reclaim the storage block is outstanding; determining, from the block tracking values, a respective cluster priority value for each of the clusters based on a count of storage blocks in the respective cluster for which a call to reclaim is outstanding; and reclaiming a first portion of storage resources in the computer system in accordance with the cluster priority values.

Abstract: A probability map of prostate tumor location is generated and displayed in response to receiving anatomic diagnostic medical imaging, such as from magnetic resonance (MR) scanning. A registration process is performed on the images in relation to a model built of prostate anatomy across different subjects in an enhanced prostate template. A probability map is created of tumor locations followed by transforming the imaging to incorporate the probability map and output a resultant image.

Abstract: In one example, a system may include an application monitoring server and an endpoint in communication with the application monitoring server. Example endpoint may include an agent to collect performance metrics associated with a program running in the endpoint and a discovery unit in communication with the agent. The discovery unit may include a metric parser to receive the performance metrics in a source format and parse the received performance metrics. Further, the discovery unit may include a resource extractor to apply a transformation definition to the parsed performance metrics to determine a plurality of resources in a destination format. The plurality of resources may be associated with an application being executed in the endpoint. Furthermore, the discovery unit may include a transmitting unit to transmit the performance metrics and first information associated with the plurality of resources to the application monitoring server via a network.

Abstract: A water drain assembly for draining water from a filter assembly comprises a conduit, a water canister, and a venturi. The conduit fluidly connects a bottom portion of the filter assembly to a bottom portion of the water canister. The venturi comprises a first venturi inlet that allows fluid to flow from the fuel tank and into the venturi, a second venturi inlet that allows fluid to flow from the water canister and into the venturi, and a venturi outlet that allows fluid to flow from the venturi and into the filter assembly. The second venturi may comprise a capillary.

Abstract: Systems, methods, and apparatus managing access to a power management device are disclosed. A system has a primary integrated circuit and a power management integrated circuit. The primary integrated circuit has a communication controller configured to control access to a first serial bus for a plurality of subsystems in the primary integrated circuit. The power management integrated circuit is coupled to the first serial bus and to a second serial bus. An access control circuit in the power management integrated circuit is configured by the primary integrated circuit to control access to the power management integrated circuit through the second serial bus. The primary integrated circuit may be configured to write an access control configuration to the power management integrated circuit. The access control configuration may define write access rights for a secondary integrated circuit coupled to the power management integrated circuit through the second serial bus.

Abstract: A system may monitor transaction data pertaining to a plurality of transaction types received by a network order fulfillment system. The system may classify the transaction data into a plurality of alarm types based on pre-defined impact of an alarm type to a given transaction type. The system may analyze a plurality of performance parameters influencing a performance of the network order fulfillment system, and identify a performance parameter exhibiting an anomaly based on historical data, a current status of the plurality of the performance parameters and a predefined prediction model. The system may ascertain whether the identified performance parameter negatively impacts the performance of the network order fulfillment system, based on evaluation rules. The system may proactively implement a remediation action to remediate a potential fault caused by the identified performance parameter when the identified performance parameter negatively impacts the performance of the network order fulfillment system.

Abstract: Example techniques for granting permissions for performing an operation related to a backup copy are described. The backup copy corresponds to first device data and the first device data is stored in a first device. In an example, in response to receiving a request to perform the operation related to the backup copy, telemetry data received from the first device is analyzed. Based on the analysis, it is determined that security of the first device is uncompromised. Based on the determination, a permission to perform the operation related to the backup copy is granted.

Abstract: In one embodiment, a system for managing a virtualization environment includes a set of host machines, each of which includes a hypervisor, virtual machines, and a virtual machine controller, and a data migration system configured to identify one or more existing storage items stored at one or more existing File Server Virtual Machines (FSVMs) of an existing virtualized file server (VFS). For each of the existing storage items, the data migration system is configured to identify a new FSVMs of a new VFS based on the existing FSVM, send a representation of the storage item from the existing FSVM to the new FSVM, such that representations of storage items are sent between different pairs of FSVMs in parallel, and store a new storage item at the new FSVM, such that the new storage item is based on the representation of the existing storage item received by the new FSVM.

Abstract: A first server can generate user profiles and receive requests from user devices for enrollment in a first server-managed system that includes user groups. The first server can provide a unique key to a user device during an enrolment process based on a user group the user device is assigned to. The first server can include an enrollment notification for the user device in a first notification transmitted to a messaging service. The messaging service can transmit a second notification to the user device, and the user device can request a user profile from a second server based on second server access information included in the second notification. The second server can use the unique key to access user profile information which it transmits to the user device based on the request. The user device can access the user profile from the profile information using the unique key.

Abstract: Described are systems and methods for assessing a likelihood of chronic thromboembolic pulmonary hypertension(CTEPH) Within a subject patient based upon an analysis of characteristics indicative of chronic thromboembolic pulmonary hypertension within an imaging study of the subject patient. The systems and methods can identify characteristics of one or more anatomical structures within a cardiac region of the subject patient indicative of CTEPH, characteristics of a pulmonary vasculature of the subject patient indicative of CTEPH, and characteristics of a chronic abnormality in a lung of the subject patient indicative of CTEPH. The systems and methods can assess these characteristics to compute the likelihood of CTEPH Within the subject patient.

Abstract: The invention relates to process for the preparation of midodrine or pharmaceutically acceptable salts thereof. The invention also relates to process for the preparation of intermediates of midodrine.

Abstract: In one embodiment, a system for managing communication connections in a virtualization environment includes a plurality of host machines implementing a virtualization environment, wherein each of the host machines includes a hypervisor, at least one user virtual machine (user VM), and a distributed file server that includes file server virtual machines (FSVMs) and associated local storage devices. Each FSVM and associated local storage device are local to a corresponding one of the host machines, and the FSVMs conduct I/O transactions with their associated local storage devices based on I/O requests received from the user VMs. Each of the user VMs on each host machine sends each of its representative I/O requests to an FSVM that is selected by one or more of the FSVMs for each I/O request based on a lookup table that maps a storage item referenced by the I/O request to the selected one of the FSVMs.