Abstract: An audio-signal generation device includes a generation circuit which generates track data and an input unit which receives information input by a user. The generation circuit generates the track data on the basis of information about the user's body, information about an exercise to be done, and information about a characteristic of a track to which the user listens during the exercise that are input via the input unit.

Abstract: The present invention provides cell fusogenic vectors having replicative ability, whose protease-dependent tropism has been modified. M gene-deficient viral vectors encoding modified F proteins, in which the cleavage site of the F protein of paramyxovirus is modified to be cleaved by different proteases, were produced. In cells transfected with these vectors, the genomic RNA present in the vectors is replicated, and cell fusogenic infection spreads to neighboring cells depending on the presence of other proteases; however, no viral particles are released. The vectors of this invention, encoding the F proteins which are cleaved by proteases whose activity is enhanced in cancer, show cancer growth suppressive effect in vivo.

Abstract: Disclosed herein is an information processing apparatus including, a wireless communication block configured to execute wireless communication with a mate terminal device, an information exchange generation condition storage block configured to record a condition of information exchange with the mate terminal device, an information exchange log storage block configured to record a log of information exchange with the mate terminal device, and an information exchange generation determination block configured to determine whether to execute information exchange with the mate terminal device by referencing the information exchange condition recorded in the information exchange generation condition storage block and the log of information exchange recorded in the information exchange log storage block.

Abstract: A content searching and presentation method in a terminal of an original user having a playlist includes the steps of accessing a playlist of a different user from the terminal and obtaining the playlist of the different user; computing a similarity between the obtained playlist of the different user and the playlist of the original user, which is a playlist owned by the terminal, in accordance with a predetermined computation equation; and presenting, as a searched result, content that is contained in the playlist of the different user and that is not contained in the playlist owned by the terminal when the computed similarity exceeds a predetermined threshold value.

Abstract: A content searching and presentation method in a terminal of an original user having a playlist includes the steps of accessing a playlist of a different user from the terminal and obtaining the playlist of the different user; computing a similarity between the obtained playlist of the different user and the playlist of the original user, which is a playlist owned by the terminal, in accordance with a predetermined computation equation; and presenting, as a searched result, content that is contained in the playlist of the different user and that is not contained in the playlist owned by the terminal when the computed similarity exceeds a predetermined threshold value.

Abstract: A file storage apparatus provides an information management method. The information management method includes correlating one or more electronic files with audible cues relative to audio content reproduced via the file storage apparatus, designating respective time intervals of the audio content during which each of the one or more electronic files can be accessed by the file storage apparatus, and retrieving the one or more electronic files of the file storage apparatus upon a predetermined user input provided to the file storage apparatus during one of the respective time intervals of the audio content.

Abstract: A seat apparatus for vehicle includes a vehicle state detecting device detecting a vehicle state, at least one position changing device changing a position of a seat, a controlling device controlling the position changing means on the basis of the vehicle state detected by the vehicle state detecting device, and the position changing device tilts an entire or a portion of a right portion of the seat and a left portion of the seat in a forward direction.

Abstract: There is provided an air conditioning register which can prevent or effectively suppress a reduction in an effective opening surface area at an air-conditioned air blow-out portion, and which has good blow-out efficiency of air-conditioned air. A first flow path 42 and a second flow path 44, whose directions toward a blow-out bezel 26 differ, are formed within a retainer 12 of an air conditioning register 10. A first damper 52 and plural second dampers 58, which are interlocked with one another, are provided at the retainer 12. The first damper 52 opens and closes the first flow path 42, and the second dampers 58 open and close the second flow path 44. The first damper 52 and the second dampers 58 are operated such that either one of the first flow path 42 and the second flow path 44 is opened and the other is closed, and the flow path of the air-conditioned air is switched.

Abstract: A imaging device includes an imaging element; a memory unit configured to temporarily store pieces of image data captured individually at predetermined timings via the imaging element; a comparator configured to compare the image data recorded in the memory unit to detect whether an image change greater than or equal to a first threshold has occurred; a determining unit configured to determine whether the image change has converged to an amount less than or equal to a second threshold by comparing the image data recorded in the memory unit when an image change greater than or equal to the first threshold has been detected; and a controller configured to exercise control so that image data captured via the imaging element is recorded on a predetermined recording medium when it is determined that the image change has converged to an amount less than or equal to the second threshold.

Abstract: The automobile of the present invention is provided with a capacitor for backup use in case of disconnection or breakdown of a battery. When a start switch is turned off, the collected charge in the capacitor is supplied to a device in which a large current is flowing, such as discharging resistor, motor or lamp, or a device in which a small current is flowing, such as dark current consuming device, and therefore, after the start switch is turned off, power consumption of the battery can be suppressed.

Abstract: A power supply system for supplying power to a plurality of loads includes a plurality of fuel cells for generating and supplying power to be supplied to the respectively corresponding loads, wherein the fuel cells are provided to correspond to the plurality of loads, a power network for receiving surplus power, which is generated ‘by the fuel cells except power to be supplied to the loads corresponding to the fuel cells, and supplying the surplus power to the loads short of power, wherein the power network is coupled to the plurality of fuel cells, and a control unit for stopping power generation of a first fuel cell among the fuel cells corresponding to a first load among the loads and controlling a second fuel cell among the fuel cells to generate power to be supplied to the first load as the surplus power if an amount of power to be supplied to the first load is less than a predetermined first threshold.

Abstract: By providing bio-information and/or environment information between a pair of users, it becomes possible for the users to understand the situation or the feeling of each other more deeply and earlier. A communication system for exchanging the situations and the feelings of both users is provided without performing optional communication operations, such as a telephone call and an e-mail. The condition or the situation on the transmitter side is to be judged and to be notified to the receiver side by inputting bio-information such as breathing, pulse-beats and heartbeats or environment information such as weather, date and hour, ambient temperature, or alternatively, by comparing, synchronizing and/or relating the bio-information and/or the environment information at present with respect to the bio-information and/or the environment information in the past. With respect to the situation of the receiver side, it is also notified similarly to the transmitter side.

Abstract: In a case where mail can not be stored in a mail box in a mail receiving server due to capacity excess, a detail content of the mail can be notified to an addressee of the mail. A mail receiving server comprises a mail receiving unit, a first mail box, a determining unit, a temporal storage space, an extracting unit, an information notice mail managing unit, and a second mail box.

Abstract: A content searching method includes the steps of: detecting movements of a user as movement information; detecting a movement pattern of the user as key information from the movement information; and searching for a piece of content having a content pattern according to the key information among a plurality of pieces of content.

Abstract: There is provided a mobile phone that detects bio-information on the user and makes information communications reflecting the detected bio-information. The mobile phone (1) includes sensors (18) that detect bio-information data. The bio-information data detected by the sensors (18) are sent to a sensor data analyzer (19) in which psychology corresponding to the detected bio-information data is analyzed based on bio-information data stored in a psychology memory (20) and psychology of the user. The sensor data analyzer (19) extracts characteristic signal patterns from the bio-information data detected by the sensors (18) and analyzes psychology corresponding to the extracted signal patterns. The psychology includes, for example, “pleased and delightful”, “discouraged”, “excited”, etc. and these states of mind are stored in association with bio-information data in the psychology memory (20).

Abstract: The present inventors succeeded in producing non-replicating SeV vectors whose genomic RNAs lack all genes for the NP, P, and L proteins, which are RNP-constituting proteins. The present inventors confirmed that the NP/P/L-deficient SeV vectors carrying a marker gene such as GFP provide high productivity, and high transfer and expression efficiencies of foreign genes (high MOI infection is essential for achieving high expression levels). By lacking the L gene or two or more of the NP, P, and L genes, the vectors of the present invention enable lowering the level of virus-derived proteins expressed in host cells, thereby reducing the immunogenicity upon in vivo administration.

Abstract: An objective of the present invention is to provide safe viral vectors for gene therapy that can be introduced by a simple technique and sufficiently express genes of interest in vivo. The present inventors demonstrated that anti-tumor effect can be produced when a heparin-binding cytokine such as granulocyte macrophage colony stimulating factor (GM-CSF) and a chemokine such as TARC or RANTES are expressed in vivo using a viral vector based on a negative-strand RNA virus. The present inventors also demonstrated that the protective effect of the vector is superior to that of conventional adenovirus vectors. Thus, the present invention relates to negative-strand RNA viral vectors comprising a cytokine gene and a chemokine gene. The viral vectors are suitable for treatment of cancers, in particular, metastatic cancers. The present invention also provides compositions comprising such viral vectors, and gene therapy methods using them.

Abstract: The present invention provides methods for producing DCs, which comprise the step of culturing DC precursor cells in the presence of multiple cytokines, dendritic cells produced thereby, and uses thereof. The methods of the present invention enable production of large quantities of DC precursors with a high ability to differentiate into DCs. The present invention enables one to obtain large quantities of DCs from a small number of DC precursor cells, and therefore makes it easier to increase the number of DCs for administration in DC-based anti-tumor immunotherapy, treatment of infection, and such. Thus, an enhancement is expected for the effect of DC vaccines.

Abstract: Music contents assigned to play lists are reproduced so as to correspond to user's preference. A music content database 7 has stored a plurality of music contents. A CPU 3 creates genre ranks such that music contents that have been more frequently, for example, reproduced are more highly ranked. In addition, the CPU 3 creates play lists corresponding, for example, to tempos and stores the created play lists in a play list database 8. The CPU 3 selects a play list corresponding to a moving tempo obtained from a tempo detection section 9 and selects music content categorized as a highly ranked genre in the genre ranks from those corresponding to the selected play list. The selected music content is supplied to a decoder and amplifier section 12 and then reproduced from a head phone 14.

Abstract: Provided is a compound useful as an N-type Ca2+ channel blocker. As a result of intensive studies of compounds having an action of blocking N-type Ca2+ channels, the present inventors found that a tetrahydroisoquinoline compound of the present invention having a substituent at the 1-position has an action of blocking the N-type Ca2+ channels, an antinociceptive pain action, an antineuropathic pain action, an abdominal pain-inhibitory action and an opioid-induced constipation-improving action, and the present invention has been completed based on these findings.