Patents by Inventor Makoto Nakayama

Makoto Nakayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11965903
    Abstract: An automated analyzer includes a reagent dispensing probe that dispenses a reagent to a reaction vessel, a sample dispensing probe that dispenses a sample to the reaction vessel, a stirring rod that stirs a sample and a reagent in the reaction vessel, and a storage unit that stores special washing information including information about a condition for performing special washing to prevent sample carryover and a washing method. The automated analyzer further includes: a determination unit that determines whether the special washing is required based on information about the sample dispensed by the sample dispensing probe and the special washing information; and a controller that causes the reagent dispensing probe to dispense a wash liquid to the reaction vessel and causes the stirring rod to stir the wash liquid in the reaction vessel based on the special washing information, when the special washing is performed.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: April 23, 2024
    Assignee: JEOL Ltd.
    Inventors: Kazushige Kojima, Yoshiyuki Nakayama, Masato Nakayama, Arihiro Toyoda, Hiroo Sugimura, Yuta Ikarashi, Yasuhiro Fukumoto, Makoto Asakura
  • Publication number: 20240101572
    Abstract: The present invention provides a compound having a PLD inhibitory activity. The present invention provides a compound of the following structural formula, and the like, or a pharmaceutically acceptable salt thereof. wherein each symbol is as defined in the description.
    Type: Application
    Filed: June 15, 2023
    Publication date: March 28, 2024
    Inventors: Masahiro YOKOTA, Tetsudo KAYA, Makoto TORIZUKA, Yasuaki NAKAYAMA, Taku IKENOGAMI, Katsuya MAEDA, Kazuki OTAKE, Kentaro SAKURAI
  • Publication number: 20240067764
    Abstract: A solid titanium catalyst component (I) for olefin polymer production contains titanium, magnesium, halogen, and a cyclic multiple-ester-group-containing compound (a) represented by the formula (1). Preferably, a propylene polymer that is obtained by the olefin polymerization method and has specific thermal properties as determined primarily by differential scanning calorimetry (DSC).
    Type: Application
    Filed: December 21, 2021
    Publication date: February 29, 2024
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Takashi KIMURA, Makoto ISOGAI, Yasushi NAKAYAMA, Kenji MICHIUE, Takashi JINNAI, Wataru YAMADA, Shotaro TAKANO, Hiroshi TERAO, Takaaki YANO, Yoshiyuki TOTANI, Sunil Krzysztof MOORTHI, Takashi NAKANO
  • Publication number: 20240067763
    Abstract: The solid titanium catalyst component (I) of the present invention contains titanium, magnesium, halogen, and a cyclic multiple-ester-group-containing compound (a) represented by the following formula (1).
    Type: Application
    Filed: August 26, 2021
    Publication date: February 29, 2024
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Takashi KIMURA, Makoto ISOGAI, Yasushi NAKAYAMA, Kenji MICHIUE, Takashi JINNAI, Wataru YAMADA, Shotaro TAKANO, Hiroshi TERAO, Takaaki YANO, Yoshiyuki TOTANI, Sunil Krzysztof MOORTHI, Takashi NAKANO
  • Publication number: 20240059788
    Abstract: The purpose of the present invention is to provide a bispecific antibody containing an antigen-binding domain which binds to CD40 and an antigen-binding domain which binds to the Epithelial Cell Adhesion Molecule (EpCAM). This invention pertains to a bispecific antibody containing an antigen-5 binding domain which binds to CD40 and an antigen-binding domain which binds to EpCAM.
    Type: Application
    Filed: August 21, 2023
    Publication date: February 22, 2024
    Applicant: Kyowa Kirin Co., Ltd.
    Inventors: Makoto Nakayama, Nobuaki Takahashi, Sayaka Maeda, Rinpei Niwa
  • Patent number: 11773180
    Abstract: An object of the present invention is to provide a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to an epithelial cell adhesion molecule (EpCAM). The present invention relates to a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to EpCAM.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: October 3, 2023
    Assignee: KYOWA KIRIN CO., LTD.
    Inventors: Makoto Nakayama, Nobuaki Takahashi, Sayaka Maeda, Rinpei Niwa
  • Patent number: 11611199
    Abstract: A fixing method of a wire harness is provided. A wire harness structure is formed by covering a wire harness with a sheet material in which a thermoplastic adhesive is coated on one surface including a required portion so as to fix the wire harness to the sheet material. The formed wire harness structure is spread on a roof liner. By pressuring the required portion warmed, the wire harness structure is fixed to the roof liner with the thermoplastic adhesive.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: March 21, 2023
    Assignee: YAZAKI CORPORATION
    Inventors: Naomi Kisu, Hisashi Takemoto, Atsuyoshi Yamaguchi, Makoto Nakayama
  • Patent number: 11221673
    Abstract: An analysis device according to the present invention includes a memory, and processing circuitry coupled to the memory and configured to analyze data indicating a biosignal by using a predetermined analysis technique and an updated parameter corresponding to the predetermined analysis technique every time the parameter is updated, control a display to display an analysis result obtained together with an interface capable of changing display modes in response to user's operation, and update the parameter based on change in the display modes for the interface.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: January 11, 2022
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Osamu Saisho, Shingo Tsukada, Kentaro Tanaka, Makoto Nakayama, Takashi Okada
  • Publication number: 20210380713
    Abstract: An object of the present invention is to provide a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to an epithelial cell adhesion molecule (EpCAM). The present invention relates to a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to EpCAM.
    Type: Application
    Filed: November 6, 2018
    Publication date: December 9, 2021
    Applicant: Kyowa Kirin Co., Ltd.
    Inventors: Makoto NAKAYAMA, Nobuaki TAKAHASHI, Sayaka MAEDA, Rinpei NIWA
  • Publication number: 20210200312
    Abstract: An analysis device according to the present invention includes a memory, and processing circuitry coupled to the memory and configured to analyze data indicating a biosignal by using a predetermined analysis technique and an updated parameter corresponding to the predetermined analysis technique every time the parameter is updated, control a display to display an analysis result obtained together with an interface capable of changing display modes in response to user's operation, and update the parameter based on change in the display modes for the interface.
    Type: Application
    Filed: May 14, 2019
    Publication date: July 1, 2021
    Applicant: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Osamu SAISHO, Shingo TSUKADA, Kentaro TANAKA, Makoto NAKAYAMA, Takashi OKADA
  • Publication number: 20210065232
    Abstract: An apparatus for detecting the number of persons contacted with an advertising medium, includes a visual-recognition range calculation unit for calculating a visual recognition ground range of the advertising medium based on a position of the advertising medium, a height above the ground of the advertising medium and a direction of an advertising surface of the advertising medium, a section extraction unit for extracting a plurality of sections in an area allowed persons to pass through, a section exclusion unit for excluding at least one section that is impossible to visually recognize the advertising medium from the plurality of sections extracted, an area specifying unit for specifying an area that contains the remaining sections except the at least one section excluded, and a contacted number calculation unit for calculating the number of persons contacted with the advertising medium by obtaining fluid population data of persons moving toward the advertising.
    Type: Application
    Filed: July 30, 2020
    Publication date: March 4, 2021
    Applicant: Kesion Co., Ltd.
    Inventors: Makoto Nakayama, Eri Ishikawa, Sakura Jinno
  • Patent number: 10686309
    Abstract: A terminal accommodating body includes a terminal accommodating chamber for each coupling terminal capable of accommodating a coupling terminal capable of being electrically connected to a terminal of an electronic component, and a terminal holding portion that holds the coupling terminal. In all the terminal accommodating chambers, in a plurality of common accommodating chambers in which the coupling terminal and one terminal portion in a one plate-like bus bar having a plurality of terminal portions electrically connectable to the terminal of the electronic component are capable of being replaced and accommodated, and a partition wall between the adjacent common accommodating chambers has an inter-chamber inserting portion into which the coupling portion is inserted in an accommodated state of the terminal portion to the common accommodating chamber, in order to accommodate a coupling portion in the common accommodating chamber.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: June 16, 2020
    Assignee: YAZAKI CORPORATION
    Inventors: Yosuke Fukuhara, Kazuki Iguchi, Tatsuya Tsubouchi, Makoto Nakayama
  • Publication number: 20200091689
    Abstract: A fixing method of a wire harness is provided. A wire harness structure is formed by covering a wire harness with a sheet material in which a thermoplastic adhesive is coated on one surface including a required portion so as to fix the wire harness to the sheet material. The formed wire harness structure is spread on a roof liner. By pressuring the required portion warmed, the wire harness structure is fixed to the roof liner with the thermoplastic adhesive.
    Type: Application
    Filed: September 11, 2019
    Publication date: March 19, 2020
    Applicant: YAZAKI CORPORATION
    Inventors: Naomi KISU, Hisashi TAKEMOTO, Atsuyoshi YAMAGUCHI, Makoto NAKAYAMA
  • Publication number: 20180375312
    Abstract: A terminal accommodating body includes a terminal accommodating chamber for each coupling terminal capable of accommodating a coupling terminal capable of being electrically connected to a terminal of an electronic component, and a terminal holding portion that holds the coupling terminal. In all the terminal accommodating chambers, in a plurality of common accommodating chambers in which the coupling terminal and one terminal portion in a one plate-like bus bar having a plurality of terminal portions electrically connectable to the terminal of the electronic component are capable of being replaced and accommodated, and a partition wall between the adjacent common accommodating chambers has an inter-chamber inserting portion into which the coupling portion is inserted in an accommodated state of the terminal portion to the common accommodating chamber, in order to accommodate a coupling portion in the common accommodating chamber.
    Type: Application
    Filed: July 27, 2018
    Publication date: December 27, 2018
    Applicant: Yazaki Corporation
    Inventors: Yosuke FUKUHARA, Kazuki IGUCHI, Tatsuya TSUBOUCHI, Makoto NAKAYAMA
  • Publication number: 20180016346
    Abstract: The present invention is related to a bispecific antibody or an antibody fragment thereof comprising an antigen binding domain that binds to a TRAILR2, and an antigen binding domain that binds to a PSMA; a nucleic acid comprising a nucleotide sequence that encodes the antibody or the antibody fragment thereof; a recombinant vector comprising the nucleic acid; a transformant comprising the recombinant vector; a method for producing the bispecific antibody or the antibody fragment thereof by using the transformant; and a reagent for detection or measurement, a diagnostic agent, and a therapeutic agent, each of which comprises the bispecific antibody or the antibody fragment thereof.
    Type: Application
    Filed: January 8, 2016
    Publication date: January 18, 2018
    Applicant: KYOWA HAKKO KIRIN CO., LTD
    Inventors: Nobuaki TAKAHASHI, Makoto NAKAYAMA, Sayaka TAKAGI
  • Patent number: 9804067
    Abstract: An observation and photography apparatus that has a polishing mechanism attached thereto. The polishing mechanism is provided with a turntable with a perpendicular rotation shaft, a polishing cloth for polishing the surface of a sample attached to the bottom surface of the turntable, and a polishing-fluid spraying nozzle disposed below the polishing cloth for spraying polishing fluid containing polishing material upward to we the polishing cloth.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: October 31, 2017
    Assignees: KAGOSHIMA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NAKAYAMADENKI CO., LTD.
    Inventors: Yoshitaka Adachi, Makoto Nakayama
  • Publication number: 20160372904
    Abstract: The present invention provides an electrical junction box capable of preventing breakage of a wire member led out to the outside a box body. A control electric wire has a length dimension that is equal to the sum of a routing length for routing an electric wire member composed of the control electric wire and a control connector along the route of an electric wire guiding portion that guides the electric wire member down to a connector retaining portion, and an extra mating length for fitting the control connector in the connector retaining portion. By the control electric wire slackened by an amount equal to the excessive mating length, the control electric wire abuts against a blocking wall continuing to a first outside surface that is provided so as to face a fixing target.
    Type: Application
    Filed: July 14, 2014
    Publication date: December 22, 2016
    Inventors: Makoto NAKAYAMA, Takahiko MITSUI, Ryo NAKANO
  • Publication number: 20160104983
    Abstract: The objectives of the present invention is to provide an electrical junction box that can sufficiently prevent the transmission of noises or vibrations emitted from an electrical component disposed inside of the electrical junction box. The electrical junction box includes: a relay having terminals; electrical wires connected to the terminals on the relay; and a casing body made of insulating resin containing the relay. The casing body is formed to have an accommodation portion that surrounds and contains the relay without contacting the same and a lead-out portion by which the electrical wires are led out of the accommodation portion. At least one of the following supporters is provided with: a first supporter for supporting the relay by an inner mold interposed between the relay and the inner face of the accommodation portion of the casing body; and a second supporter for supporting the relay via the electrical wires.
    Type: Application
    Filed: December 17, 2015
    Publication date: April 14, 2016
    Inventors: Makoto Nakayama, Takahiko Mitsui, Ryo Nakano
  • Patent number: 9226417
    Abstract: A lock mechanism includes: a lock arm provided in a cantilever manner on an inner wall of a part compartment of a box body of an electric connection box; and a lock projection provided to the lock arm on its surface facing a part housed in the part compartment. The lock arm can be divided in a longitudinal direction into: a base end region fixed to the inner wall; upper end region located in the free end which interferes with the part and receives a pressing force for unlocking operation; and a middle region located within a predetermined distance range between the base and upper end region. The flexural rigidity of the base and upper end region is set larger than that of the middle region by providing ribs on the base and upper end region and providing no ribs on the middle region.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: December 29, 2015
    Assignee: Yazaki Corporation
    Inventors: Makoto Nakayama, Masahiro Kanamaru
  • Patent number: 9162636
    Abstract: An electric connection box 1 includes a bracket 2 in which a plurality of connectors 7a, 7b, 8a, 8b, 9a, 9b, 10a, 10b, 10b? joined with each end of electric wires 11, and a case main body 3 receiving the bracket 2. The electric connection box is provided with a mount device 81 mounting the bracket 2 in the case main body 3 movably between a near position near an opening 3a of a case main body 3 and a fix position 3c deeper than the near position near the opening 3c in the case main body 3, and a maintain device 82 maintaining a state that the bracket 2 is positioned at the near position near the opening 3a, and a fix device 83 fixing the bracket 2 positioned at the fix position 3c at the case main body 3.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: October 20, 2015
    Assignee: Yazaki Corporation
    Inventors: Makoto Nakayama, Norio Ito, Ryo Nakano, Tatsuya Tsubouchi