Patents by Inventor Makoto Nakayama
Makoto Nakayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11965903Abstract: An automated analyzer includes a reagent dispensing probe that dispenses a reagent to a reaction vessel, a sample dispensing probe that dispenses a sample to the reaction vessel, a stirring rod that stirs a sample and a reagent in the reaction vessel, and a storage unit that stores special washing information including information about a condition for performing special washing to prevent sample carryover and a washing method. The automated analyzer further includes: a determination unit that determines whether the special washing is required based on information about the sample dispensed by the sample dispensing probe and the special washing information; and a controller that causes the reagent dispensing probe to dispense a wash liquid to the reaction vessel and causes the stirring rod to stir the wash liquid in the reaction vessel based on the special washing information, when the special washing is performed.Type: GrantFiled: May 28, 2020Date of Patent: April 23, 2024Assignee: JEOL Ltd.Inventors: Kazushige Kojima, Yoshiyuki Nakayama, Masato Nakayama, Arihiro Toyoda, Hiroo Sugimura, Yuta Ikarashi, Yasuhiro Fukumoto, Makoto Asakura
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Publication number: 20240101572Abstract: The present invention provides a compound having a PLD inhibitory activity. The present invention provides a compound of the following structural formula, and the like, or a pharmaceutically acceptable salt thereof. wherein each symbol is as defined in the description.Type: ApplicationFiled: June 15, 2023Publication date: March 28, 2024Inventors: Masahiro YOKOTA, Tetsudo KAYA, Makoto TORIZUKA, Yasuaki NAKAYAMA, Taku IKENOGAMI, Katsuya MAEDA, Kazuki OTAKE, Kentaro SAKURAI
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Publication number: 20240067764Abstract: A solid titanium catalyst component (I) for olefin polymer production contains titanium, magnesium, halogen, and a cyclic multiple-ester-group-containing compound (a) represented by the formula (1). Preferably, a propylene polymer that is obtained by the olefin polymerization method and has specific thermal properties as determined primarily by differential scanning calorimetry (DSC).Type: ApplicationFiled: December 21, 2021Publication date: February 29, 2024Applicant: MITSUI CHEMICALS, INC.Inventors: Takashi KIMURA, Makoto ISOGAI, Yasushi NAKAYAMA, Kenji MICHIUE, Takashi JINNAI, Wataru YAMADA, Shotaro TAKANO, Hiroshi TERAO, Takaaki YANO, Yoshiyuki TOTANI, Sunil Krzysztof MOORTHI, Takashi NAKANO
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Publication number: 20240067763Abstract: The solid titanium catalyst component (I) of the present invention contains titanium, magnesium, halogen, and a cyclic multiple-ester-group-containing compound (a) represented by the following formula (1).Type: ApplicationFiled: August 26, 2021Publication date: February 29, 2024Applicant: MITSUI CHEMICALS, INC.Inventors: Takashi KIMURA, Makoto ISOGAI, Yasushi NAKAYAMA, Kenji MICHIUE, Takashi JINNAI, Wataru YAMADA, Shotaro TAKANO, Hiroshi TERAO, Takaaki YANO, Yoshiyuki TOTANI, Sunil Krzysztof MOORTHI, Takashi NAKANO
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Publication number: 20240059788Abstract: The purpose of the present invention is to provide a bispecific antibody containing an antigen-binding domain which binds to CD40 and an antigen-binding domain which binds to the Epithelial Cell Adhesion Molecule (EpCAM). This invention pertains to a bispecific antibody containing an antigen-5 binding domain which binds to CD40 and an antigen-binding domain which binds to EpCAM.Type: ApplicationFiled: August 21, 2023Publication date: February 22, 2024Applicant: Kyowa Kirin Co., Ltd.Inventors: Makoto Nakayama, Nobuaki Takahashi, Sayaka Maeda, Rinpei Niwa
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Patent number: 11773180Abstract: An object of the present invention is to provide a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to an epithelial cell adhesion molecule (EpCAM). The present invention relates to a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to EpCAM.Type: GrantFiled: November 6, 2018Date of Patent: October 3, 2023Assignee: KYOWA KIRIN CO., LTD.Inventors: Makoto Nakayama, Nobuaki Takahashi, Sayaka Maeda, Rinpei Niwa
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Patent number: 11611199Abstract: A fixing method of a wire harness is provided. A wire harness structure is formed by covering a wire harness with a sheet material in which a thermoplastic adhesive is coated on one surface including a required portion so as to fix the wire harness to the sheet material. The formed wire harness structure is spread on a roof liner. By pressuring the required portion warmed, the wire harness structure is fixed to the roof liner with the thermoplastic adhesive.Type: GrantFiled: September 11, 2019Date of Patent: March 21, 2023Assignee: YAZAKI CORPORATIONInventors: Naomi Kisu, Hisashi Takemoto, Atsuyoshi Yamaguchi, Makoto Nakayama
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Patent number: 11221673Abstract: An analysis device according to the present invention includes a memory, and processing circuitry coupled to the memory and configured to analyze data indicating a biosignal by using a predetermined analysis technique and an updated parameter corresponding to the predetermined analysis technique every time the parameter is updated, control a display to display an analysis result obtained together with an interface capable of changing display modes in response to user's operation, and update the parameter based on change in the display modes for the interface.Type: GrantFiled: May 14, 2019Date of Patent: January 11, 2022Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATIONInventors: Osamu Saisho, Shingo Tsukada, Kentaro Tanaka, Makoto Nakayama, Takashi Okada
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Publication number: 20210380713Abstract: An object of the present invention is to provide a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to an epithelial cell adhesion molecule (EpCAM). The present invention relates to a bispecific antibody comprising an antigen-binding domain that binds to CD40 and an antigen-binding domain that binds to EpCAM.Type: ApplicationFiled: November 6, 2018Publication date: December 9, 2021Applicant: Kyowa Kirin Co., Ltd.Inventors: Makoto NAKAYAMA, Nobuaki TAKAHASHI, Sayaka MAEDA, Rinpei NIWA
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Publication number: 20210200312Abstract: An analysis device according to the present invention includes a memory, and processing circuitry coupled to the memory and configured to analyze data indicating a biosignal by using a predetermined analysis technique and an updated parameter corresponding to the predetermined analysis technique every time the parameter is updated, control a display to display an analysis result obtained together with an interface capable of changing display modes in response to user's operation, and update the parameter based on change in the display modes for the interface.Type: ApplicationFiled: May 14, 2019Publication date: July 1, 2021Applicant: NIPPON TELEGRAPH AND TELEPHONE CORPORATIONInventors: Osamu SAISHO, Shingo TSUKADA, Kentaro TANAKA, Makoto NAKAYAMA, Takashi OKADA
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Publication number: 20210065232Abstract: An apparatus for detecting the number of persons contacted with an advertising medium, includes a visual-recognition range calculation unit for calculating a visual recognition ground range of the advertising medium based on a position of the advertising medium, a height above the ground of the advertising medium and a direction of an advertising surface of the advertising medium, a section extraction unit for extracting a plurality of sections in an area allowed persons to pass through, a section exclusion unit for excluding at least one section that is impossible to visually recognize the advertising medium from the plurality of sections extracted, an area specifying unit for specifying an area that contains the remaining sections except the at least one section excluded, and a contacted number calculation unit for calculating the number of persons contacted with the advertising medium by obtaining fluid population data of persons moving toward the advertising.Type: ApplicationFiled: July 30, 2020Publication date: March 4, 2021Applicant: Kesion Co., Ltd.Inventors: Makoto Nakayama, Eri Ishikawa, Sakura Jinno
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Patent number: 10686309Abstract: A terminal accommodating body includes a terminal accommodating chamber for each coupling terminal capable of accommodating a coupling terminal capable of being electrically connected to a terminal of an electronic component, and a terminal holding portion that holds the coupling terminal. In all the terminal accommodating chambers, in a plurality of common accommodating chambers in which the coupling terminal and one terminal portion in a one plate-like bus bar having a plurality of terminal portions electrically connectable to the terminal of the electronic component are capable of being replaced and accommodated, and a partition wall between the adjacent common accommodating chambers has an inter-chamber inserting portion into which the coupling portion is inserted in an accommodated state of the terminal portion to the common accommodating chamber, in order to accommodate a coupling portion in the common accommodating chamber.Type: GrantFiled: July 27, 2018Date of Patent: June 16, 2020Assignee: YAZAKI CORPORATIONInventors: Yosuke Fukuhara, Kazuki Iguchi, Tatsuya Tsubouchi, Makoto Nakayama
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Publication number: 20200091689Abstract: A fixing method of a wire harness is provided. A wire harness structure is formed by covering a wire harness with a sheet material in which a thermoplastic adhesive is coated on one surface including a required portion so as to fix the wire harness to the sheet material. The formed wire harness structure is spread on a roof liner. By pressuring the required portion warmed, the wire harness structure is fixed to the roof liner with the thermoplastic adhesive.Type: ApplicationFiled: September 11, 2019Publication date: March 19, 2020Applicant: YAZAKI CORPORATIONInventors: Naomi KISU, Hisashi TAKEMOTO, Atsuyoshi YAMAGUCHI, Makoto NAKAYAMA
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Publication number: 20180375312Abstract: A terminal accommodating body includes a terminal accommodating chamber for each coupling terminal capable of accommodating a coupling terminal capable of being electrically connected to a terminal of an electronic component, and a terminal holding portion that holds the coupling terminal. In all the terminal accommodating chambers, in a plurality of common accommodating chambers in which the coupling terminal and one terminal portion in a one plate-like bus bar having a plurality of terminal portions electrically connectable to the terminal of the electronic component are capable of being replaced and accommodated, and a partition wall between the adjacent common accommodating chambers has an inter-chamber inserting portion into which the coupling portion is inserted in an accommodated state of the terminal portion to the common accommodating chamber, in order to accommodate a coupling portion in the common accommodating chamber.Type: ApplicationFiled: July 27, 2018Publication date: December 27, 2018Applicant: Yazaki CorporationInventors: Yosuke FUKUHARA, Kazuki IGUCHI, Tatsuya TSUBOUCHI, Makoto NAKAYAMA
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Publication number: 20180016346Abstract: The present invention is related to a bispecific antibody or an antibody fragment thereof comprising an antigen binding domain that binds to a TRAILR2, and an antigen binding domain that binds to a PSMA; a nucleic acid comprising a nucleotide sequence that encodes the antibody or the antibody fragment thereof; a recombinant vector comprising the nucleic acid; a transformant comprising the recombinant vector; a method for producing the bispecific antibody or the antibody fragment thereof by using the transformant; and a reagent for detection or measurement, a diagnostic agent, and a therapeutic agent, each of which comprises the bispecific antibody or the antibody fragment thereof.Type: ApplicationFiled: January 8, 2016Publication date: January 18, 2018Applicant: KYOWA HAKKO KIRIN CO., LTDInventors: Nobuaki TAKAHASHI, Makoto NAKAYAMA, Sayaka TAKAGI
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Patent number: 9804067Abstract: An observation and photography apparatus that has a polishing mechanism attached thereto. The polishing mechanism is provided with a turntable with a perpendicular rotation shaft, a polishing cloth for polishing the surface of a sample attached to the bottom surface of the turntable, and a polishing-fluid spraying nozzle disposed below the polishing cloth for spraying polishing fluid containing polishing material upward to we the polishing cloth.Type: GrantFiled: June 18, 2013Date of Patent: October 31, 2017Assignees: KAGOSHIMA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NAKAYAMADENKI CO., LTD.Inventors: Yoshitaka Adachi, Makoto Nakayama
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Publication number: 20160372904Abstract: The present invention provides an electrical junction box capable of preventing breakage of a wire member led out to the outside a box body. A control electric wire has a length dimension that is equal to the sum of a routing length for routing an electric wire member composed of the control electric wire and a control connector along the route of an electric wire guiding portion that guides the electric wire member down to a connector retaining portion, and an extra mating length for fitting the control connector in the connector retaining portion. By the control electric wire slackened by an amount equal to the excessive mating length, the control electric wire abuts against a blocking wall continuing to a first outside surface that is provided so as to face a fixing target.Type: ApplicationFiled: July 14, 2014Publication date: December 22, 2016Inventors: Makoto NAKAYAMA, Takahiko MITSUI, Ryo NAKANO
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Publication number: 20160104983Abstract: The objectives of the present invention is to provide an electrical junction box that can sufficiently prevent the transmission of noises or vibrations emitted from an electrical component disposed inside of the electrical junction box. The electrical junction box includes: a relay having terminals; electrical wires connected to the terminals on the relay; and a casing body made of insulating resin containing the relay. The casing body is formed to have an accommodation portion that surrounds and contains the relay without contacting the same and a lead-out portion by which the electrical wires are led out of the accommodation portion. At least one of the following supporters is provided with: a first supporter for supporting the relay by an inner mold interposed between the relay and the inner face of the accommodation portion of the casing body; and a second supporter for supporting the relay via the electrical wires.Type: ApplicationFiled: December 17, 2015Publication date: April 14, 2016Inventors: Makoto Nakayama, Takahiko Mitsui, Ryo Nakano
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Patent number: 9226417Abstract: A lock mechanism includes: a lock arm provided in a cantilever manner on an inner wall of a part compartment of a box body of an electric connection box; and a lock projection provided to the lock arm on its surface facing a part housed in the part compartment. The lock arm can be divided in a longitudinal direction into: a base end region fixed to the inner wall; upper end region located in the free end which interferes with the part and receives a pressing force for unlocking operation; and a middle region located within a predetermined distance range between the base and upper end region. The flexural rigidity of the base and upper end region is set larger than that of the middle region by providing ribs on the base and upper end region and providing no ribs on the middle region.Type: GrantFiled: April 18, 2008Date of Patent: December 29, 2015Assignee: Yazaki CorporationInventors: Makoto Nakayama, Masahiro Kanamaru
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Patent number: 9162636Abstract: An electric connection box 1 includes a bracket 2 in which a plurality of connectors 7a, 7b, 8a, 8b, 9a, 9b, 10a, 10b, 10b? joined with each end of electric wires 11, and a case main body 3 receiving the bracket 2. The electric connection box is provided with a mount device 81 mounting the bracket 2 in the case main body 3 movably between a near position near an opening 3a of a case main body 3 and a fix position 3c deeper than the near position near the opening 3c in the case main body 3, and a maintain device 82 maintaining a state that the bracket 2 is positioned at the near position near the opening 3a, and a fix device 83 fixing the bracket 2 positioned at the fix position 3c at the case main body 3.Type: GrantFiled: May 11, 2011Date of Patent: October 20, 2015Assignee: Yazaki CorporationInventors: Makoto Nakayama, Norio Ito, Ryo Nakano, Tatsuya Tsubouchi