Abstract: A method, system, and computer program product for managing user identification codes in an interne advertising environment. One aspect implements a system including a database engine to store a plurality of signals comprising characteristics and/or values received from a user device. A user ID generator calculates collision statistics and/or fragmentation statistics to form a first mapping function that is in turn used to generate a plurality of identification codes based at least in part a first set of selected signals. A calibration module produces measurements determined from collision quantities and/or fragmentation quantities using the first mapping function, wherein the measurements are determined by comparing the plurality of identification codes to entries in a known ID database. A sequencing module generates updated sequences of mapping functions.

Abstract: The present disclosure features useful methods to treat an ALT-positive cancer and/or a cancer having a deficiency in ATRX and/or DAXX, e.g., in a subject in need thereof. In some embodiments, the methods described herein are useful in the treatment of cancer in combination with anti-cancer therapies.

Abstract: A method of navigating a visually impaired user, a navigation system and a guiding robot used in the system. The method includes the steps of: receiving a plurality of location referencing signals from a plurality of signal sources; processing the location referencing signals to determine a current location of the user in a predetermined area; planning an optimal path for the user to travel from the current location to a destination location; providing guiding information associated with the optimal path to the user; obtaining a travel instruction from the user to travel along the optimal path; and moving a guiding robot according to the travel instruction provided by the user along the optimal path until the next travel instruction is required to further move the guiding robot.

Abstract: The present invention provides a multi-layered interlaced membrane comprising at least one substrate layer including a plurality of first polymer-based microfibers; at least one nanofibrous layer including a plurality of second polymer-based nanofibers where each of the nanofibers has one or more nano-branches; at least one interlaced layer including a plurality of third polymer-based submicron fibers where each of the submicron fibers has one or more nano-branches and a plurality of fourth polymer-based nanofibers where each of the nanofibers has one or more nano-branches, wherein the third polymer-based submicron fibers are interlaced with the fourth polymer-based nanofibers; at least one submicron fibrous layer including a plurality of fifth polymer-based submicron fibers where each of the submicron fibers has one or more nano-branches.

Abstract: Systems, methods, and apparatuses can determine and use methylation profiles of various tissues and samples. Examples are provided. A methylation profile can be deduced for fetal/tumor tissue based on a comparison of plasma methylation (or other sample with cell-free DNA) to a methylation profile of the mother/patient. A methylation profile can be determined for fetal/tumor tissue using tissue-specific alleles to identify DNA from the fetus/tumor when the sample has a mixture of DNA. A methylation profile can be used to determine copy number variations in genome of a fetus/tumor. Methylation markers for a fetus have been identified via various techniques. The methylation profile can be determined by determining a size parameter of a size distribution of DNA fragments, where reference values for the size parameter can be used to determine methylation levels. Additionally, a methylation level can be used to determine a level of cancer.

Abstract: Example embodiments relate to endoscopic systems, devices, and methods. The system may include a main assembly having a main assembly body and expandable member. Main assembly body may include a proximal region, distal region, and central region having a pressure opening for providing positive pressure. Expandable member may have a tubular structure with interior channel, inward facing interior surface, outward facing exterior surface, and first and second ends. Interior channel may house the central region of the main assembly body. First end of the expandable member may be secured to the proximal region of the main assembly body. Second end of the expandable member may be secured to the distal region of the main assembly body. When the pressure opening provides positive pressure, the tubular structure of the expandable member between the first and second ends of the expandable member may expand outwardly away from the central region.

Abstract: A system includes reception of a request to execute queries associated with an interactive data visualization, building, based on the request, of all queries required by the interactive data visualization on a background thread, reception of a query response associated with each built query on the background thread, building of a final response on the background thread based on the received query responses, and rendering, on a main thread, of the interactive data visualization based on the final response.

Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

Abstract: The present invention provides a contactless elevator control system and method. The system comprises an infrared touch sensor, a relay control device and an elevator button control device, wherein: the infrared touch sensor emits an array of multiple infrared beams, receives reflected infrared beams, calculates a vertical and lateral displacement, determines a corresponding coordinate information, calculates a corresponding elevator button, and sends a corresponding control; the relay control device drives the corresponding relay contacts to close. The solution uses the infrared touch sensor to achieve contactless control of elevator buttons, reducing the risk of spreading bacteria and viruses when touching the elevator buttons.

Abstract: A method for accessing data stored in a database may include receiving, at an application, a request to load a data story that includes a software widget configured to create, based on a portion of data stored in a database coupled with a cloud-based analytics engine, a data presentation providing a visual representation of the portion of data. In response to the request to load the data story, a scripting engine associated with the application may execute a first programming code associated with the software widget. The first programming code may be executed to retrieve, from the cloud-based analytics engine, visualization data for rendering the data presentation. An in-app web browser associated with the application may execute a second programming code associated with the software widget. The second programming code may be executed to render, based on the visualization data retrieved from the cloud-based analytics engine, the data presentation.

Abstract: A system and method for creating customized insurance-related forms (e.g., agreements, policies, exceptions, and other insurance-related documents) using computing devices is disclosed. A user can quickly and conveniently create customized insurance-related forms, and can transmit same to one or more remote users and/or computing systems for further processing. The system provides rich tagged searching and editing features for allowing an insurance professional to rapidly create customized forms, and to access other forms while editing a given form. The system ingests and decomposes insurance-related forms into clauses, applies search tags to the clauses, and stores the clauses and the search tags in a database for rapid searching and retrieval of desired tags for use in creating customized forms.

Abstract: Some embodiments provide a non-transitory machine-readable medium that stores a program. The program receives a first request for a visualization of data. In response to the first request, the program further retrieves the data from a storage of a computing system. The program also generates the visualization based on the data from the storage of the computing system. The program further stores the data in a storage of the device. The program also receives a second request for the visualization of the data. The program further determines that the device is unable to communicate with the computing system. In response to the determination, the program also retrieves the data from the storage of the device. The program further generates the visualization based on the data retrieved from the storage of the device.

Abstract: Systems and methods for generating prebuilt machine learning framework objects comprising sets of prebuilt machine learning components and one or more data mapping requirements. The components are associated with a respective machine learning service. One or more datasets are obtained. A user-specified context for creating a particular machine learning application is obtained. A particular prebuilt object is selected based on the datasets and the context. One more candidate data mappings are identified based on the data mapping requirements and the datasets. A particular data mapping is selected. A particular set of prebuilt components is selected from the plurality of prebuilt components. The particular machine learning application is generated from the particular prebuilt object based on the particular data mapping and the particular set of prebuilt components, the particular machine learning application comprising an executable application. The machine learning application is deployed.

Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.

Abstract: A system and a method for a security strap device including a strap; a lock, the lock comprising a locking mechanism; a fixed portion of the strap being secured inside the lock; a free end of the strap insertable into the lock to form a loop in the strap, the lock is configured to lock a portion of the strap to form the loop in the strap, wherein; the locking mechanism comprises a plurality of latches moveable between a locking position and an unlocking position; the plurality of latches engaging one or more locking slots within the lock when in the locking position to the lock the strap within the lock; and wherein the latches are all simultaneously biased toward the locked position and the latches are required to be simultaneously displaced to an unlocking position to unlock the strap.

Abstract: The present disclosure relates to methods for producing water repellent textile substrates and products thereof. The methods can be conducted without the use of perfluorocarbons.

Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.

Abstract: A method and system for using a wavelength tunable semiconductor laser as an excitation source of a fiber optics sensing system (FOSS) based on a thermoelectric control of a laser sweep. A device can include an optical fiber; a set of fiber Bragg gratings disposed within the optical fiber; a single-frequency laser (SFL) operatively connected to the optical fiber; a thermoelectric cooler operatively connected to the SFL; a controller comprising a processor in communication with the thermoelectric cooler; and a nontransitory, computer-readable storage medium in communication with the processor. The nontransitory, computer-readable storage medium can store instructions that, when executed by the processor, cause the processor to perform operations including determining a strain value at a first fiber Bragg grating of the set of fiber Bragg gratings based on a second laser signal received at the device that is reflected from an interaction of a first laser signal with the first fiber Bragg grating.

Abstract: A system and method for creating customized insurance-related forms (e.g., agreements, policies, exceptions, and other insurance-related documents) using computing devices is disclosed. A user can quickly and conveniently create customized insurance-related forms, and can transmit same to one or more remote users and/or computing systems for further processing. The system provides rich tagged searching and editing features for allowing an insurance professional to rapidly create customized forms, and to access other forms while editing a given form. The system ingests and decomposes insurance-related forms into clauses, applies search tags to the clauses, and stores the clauses and the search tags in a database for rapid searching and retrieval of desired tags for use in creating customized forms.

Abstract: Some embodiments provide a program. The program receives from a first webview a first request for data for a first visualization in a plurality of visualizations specified in a visualization collection definition. The program further retrieves the data for the first visualization in the plurality of visualizations. The program also sends the first webview the data for the first visualization in order for the first webview to render the first visualization. The program further receives from a second webview a second request for data for a second visualization in the plurality of visualizations specified in the visualization collection definition. The program also retrieves the data for the second visualization in the plurality of visualizations using the background processing thread. The program further sends the second webview the data for the second visualization in order for the second webview to render the second visualization.