Abstract: A pressure-liquefied propellant mixture for aerosols, comprising dinitrogen monoxide and a hydrofluoroalkane having 1 to 3 carbon atoms, in particular 1,1,1,2-tetrafluoroethane and/or 1,1,1,2,3,3,3-heptafluoropropane, makes possible an improvement in the wetting properties of pharmaceutically active compounds, whereby the formulation problems existing with hydrofluoroalkanes can be overcome with respect to suspension and solution aerosols and thus improved medicinal aerosol formulations can be obtained. With the aid of dinitrogen monoxide, it is also possible to influence the pressure and thus the particle size distribution specifically and, by displacement of oxygen from the hydrofluoroalkanes, to improve the storage stability of oxidation-sensitive active compounds. If desired, the propellant mixture can additionally contain carbon dioxide.

Abstract: The use of solid, pharmaceutically acceptable salts of cromoglycic acid and/or nedocromil as carriers in a therapeutically and prophylactically inefficacious amount in suspension aerosol formulations of pharmaceutical active compounds improves the dispersion properties, increases the chemical and physical stability of moisture-sensitive active compounds, makes possible a more accurate dosage, in particular even of low-dose active compounds, and as a rule permits the abandonment of surface-active agents.

Abstract: A pressure-liquefied propellant mixture for aerosols, comprising a fluorinated alkane, in particular 1,1,1,2-tetrafluoroethane and/or 1,1,1,2,3,3,3-heptafluoropropane, and carbon dioxide, makes possible an improvement of the wetting properties of pharmaceutically active compounds, with which the formulation problems existing with hydrofluoroalkanes in relation to suspension as well as solution aerosols can be overcome and thus improved medicinal aerosol formulations can be obtained. With the aid of carbon dioxide, it is also possible to specifically influence the pressure and thus the particle size distribution and also by displacement of oxygen from the hydrofluoroalkanes to improve the storage stability of oxidation-sensitive active compounds.

Abstract: An inhaler for multiple dosed administration of a pharmacological dry powder consists externally of a housing (100,150) and of a protective cap (950) which can be removed from a special mouthpiece (900) fitted on the housing. Arranged on the inside there are a slide rail (200), a dosing slide (300), a shutter (400), a carriage (500), a funnel arrangement (600), a counter device (700), a valve shield (800) and a valve guide (850). Removal of the protective cap (950) initiates the dosing, with a dose received in the dosing cavity (302) being transported to the mouth-piece (900) by means of the dosing slide (300). Only upon application of a defined minimum intensity of inhalation is the shutter (400) moved by the suctioned valve shield (800), as a result of which the dose is released for inhalation. Completed with an electronic module and a controllable nozzle, all inhalation-relevant data can be recorded and the flow conditions regulated.

Abstract: This invention relates to highly active and solid pharmaceutical preparations rapidly releasing the active substance for the treatment of diabetes, particularly: 1. liquid formulations of glibenclamide consisting of 1 part of glibenclamide and 4 to 1500 parts of liquid sugar alcohols such as 70% sorbitol solution or glycol such as propylene glycol, hexylene glycol, di-, tri- or polyethylene glycol having a molecular weight from 76 to 600, optionally 0.5 to 2 moles of an alkaline reacting substance and other drug additives; 2.

Abstract: A method of producing a vacuum in a volume of a hollow body which has at least one outlet opening for the gaseous atmosphere present therein, the method includes the following steps: introducing at least about 3 g/dm.sup.3 of evacuation volume of a metal hydride into the hollow body so as to take up less than about 5% of the volume 3. The metal hydride comprises a hydride forming alloy of the formulaTi(V.sub.1-a-b Fe.sub.a Al.sub.b).sub.xy Mn.sub.z,wherein1<x.ltoreq.20<y.ltoreq.0.2x+y.ltoreq.20<a.ltoreq.0.40<b.ltoreq.0.2a+b.ltoreq.0.5(1-a-b) x.gtoreq.10<z.ltoreq.2-x-y.The metal hydride is heated to a temperature so that a substantial amount of the gaseous hydrogen is released from the hydride, the heating step is performed so that heating of the hollow body will not exceed a temperature of about 500.degree. C.

Abstract: A rotary valve assembly having a valve sleeve and a rotary valve core are provided with flow control grooves having control edges distributed over the peripheries for regulation of pressurized fluid. Such pressure regulation occurs at the control edges forming sets of three gaps in each rotational direction of the steering control valve. One of such gaps forms a relatively deep return flow passage that is fully opened in the neutral position of the valve assembly and two throttle gaps on opposite sides thereof that are relatively shallow for restricted return flow. Rotational displacement of the valve core initially effects pressure regulation through the intermediate deep gap within a low pressure range.

Abstract: For the determination of filterable pollutants in gases there is a filter sc, which is located on a horizontal, compact rotary plate, which is moved over a suction head, whose suction lips interact with corresponding holes or borings in the rotary plate. The suction head is pushed upon from underneath by action of a universal-joint spring bearing against the plane-parallel rotary plate. Preferably, the rotary plate is rotated each time in steps at determined cycle times, specifically according to a program, by a determined number of collection spaces with "phase-shifted" multiple rotations of the plate, until the filter surface is completely used up. Instead of a filter disc, absorber material can also be used for radioactivity monitoring with a forward motion cycle of 1 to 2 days.

Abstract: Proportional counters for the detection and measurement of radioactive surface contaminations are provided with at least two flat window faces enclosing an angle and being formed by a thin foil spread or stretched by a framework including thin rods arranged along the inner edges of contacting window faces, to which rods the foil may be adhered. A perforated lattice or grid cage serves in particular to protect the thin window against any contact, the cage provides for a spacing of about double rod thickness between the framework and the controlled surface. Preferred is a polygonal and in particular hexagonal lattice whose grid wires or strips do not lie in the main scanning direction. Particularly convenient for checking pipelines are, for example, cylindrical measuring probes comprising window foils extending over and perhaps adhered to a circularly arranged frame of thin rods.

Abstract: A fastening clip configured for rotation in a housing bore, the clip fashioned to house a beveled terminal region of a linkage of circular cross-section. So that the clip rotates spontaneously into a correct installation position during assembly of the linkage, a plurality of clip orifices are provided and the walls of an associated introductory channel are beveled so that an introductory bevel extends from every point on the edge of the clip to intersect a clip orifice.

Abstract: An ionization chamber of reduced size, with an end window of a diameter preferably smaller than 3 cm is mounted on the end of a hand probe containing an amplifier, the output of which goes through a cable to an indicating device. One of a set of aperture diaphragms may be slipped over the end window to reduce the area of the window transparent to beta rays. In addition to the end window, slots in the cylindrical wall of the chamber increase the solid angle through which radiation may enter the chamber. The end window and the slotted walls of the chamber are covered with tissue-equivalent material for measurement of radiation exposure dose by the electrodes of the chamber and their associated amplifier and indicator. An alternative design with a conical chamber and conical inner electrode and a smaller window provides reliable measurement, even in inhomogeneous radiation fields without the necessity of using diaphragms.

Abstract: Three dosimeter disks of a thickness increasing towards the base piece which is to lie against the skin are used, with a covering of .beta. ray window for thermoluminescence dosimetry. In order to provide dosimetry referred to a 70 um depth of living tissue, corresponding to a weight of material per unit area of 7 mg/cm.sup.2, it is found that the thermoluminescent dosimeter (TLD) disk, which is next to the .beta. window, should have a weight per unit area in the range from 15 to 30 mg/cm.sup.2. A three-disk dosimeter should have TLD disks of increasing weight per unit area in the ratio 1:3:7 or, at any rate, the weight of the middle disk should be in the range from 30 to 90 mg/cm.sup.2, and the third disk should have a weight of at least 90 mg/cm.sup.2. TLD's are conventionally made of LiF crystals embedded in PTFE.

Abstract: The overhead conveyor comprises a main track and a branch track connected to the main track in a switch point, the tracks having a shape of a box-like beam with a longitudinal slit in its bottom flange for suspending a trolley carriage, the carriage supporting a rocking lever having at its ends guiding rollers, the operation of the switch point being safeguarded via tiltable tongues arranged on the lower flange of the track and cooperating with slide shoes provided on the ends of the rocking lever, and by means of locking rails attached to the side walls of the track to lock the rocking lever in the desired angular position; the ends of the rocking lever further support safety noses each having an inclined surface of a length sufficient for bridging the gap between the ends of the inclined tongues and the beginning of the locking rail when the slide shoe still engages the end portion of the safety tong.

Abstract: A screen printing apparatus includes a stencil and a doctor blade or a squeegee cooperating with the printing screen or stencil to print images on objects. A transportation arrangement is provided for transporting the objects on which the images are to be printed in a given path and direction, part of the path leading past the stencil. The transportation arrangement includes a plurality of pairs of support members which are respectively mounted on carrier elements extending laterally of the path. The carrier elements are mounted on elongated rails for movement longitudinally thereof by a distance corresponding to the spacing of the pairs of support members from one another in said direction, the carrier elements reciprocating in said direction and in an opposite direction relative to the rails.

Abstract: There is disclosed a control valve arrangement for power steering systems having a servomotor piston which carries a piston valve constructed with a pair of reaction chambers having relief valves and communicating with each other in such a manner as to provide variable resistance against the manual force being applied to a steering wheel which actuates the piston valve. The purpose of thus effecting an automatically varying force is to impart to the vehicle driver a simulated sense of mechanical steering, i.e., simulated road resistance feel, but with a decreasing requirement of force expenditure during vehicle parking operations, or during low speed driving. The construction permits the use of simple parts in a very compact arrangement in which either reaction chamber imparts road resistance feel by being subjected only to servopump inlet pressure while the other is subjected to exhaust pressure. The unbalance of force acts on the piston valve in a direction opposite the manually impressed force.