Abstract: The disclosure generally relates to a system for perfusing an ex-vivo liver including a pump configured to pump a perfusion fluid through a perfusion circuit, the pump in fluid communication with a hepatic artery interface and a portal vein interface; an oxygenator; a heater; an inferior vena cava interface in fluid communication with an inferior vena cava of the ex-vivo liver; and a reservoir configured to receive the perfusion fluid from the inferior vena cava of the ex-vivo liver and store a volume of fluid.

Abstract: This disclosure describes methods and compositions for detecting the presence of a Perilipin 1 (PLIN1) autoantibody in a biological sample obtained from a subject that has or is being treated with immune checkpoint inhibitor therapy. Also provided are methods of treating subjects with acquired lipodystrophy.

Abstract: A method for synthesizing a purified lithium (Li)+ anion binding agent (ABA-F)? salt and the corresponding Li+(ABA-F)? are disclosed. The method includes dissolving a boron-based acid in a polar solvent to form a solution. The solution is refluxed to form an anion binding agent. A stoichiometric amount of a small fluorinated salt, such as LiF, is added to the anion binding agent to form a mixture. The mixture is subsequently crystallized to obtain a substantially pure Li+(ABA-F)? salt. Example purified Li+(ABA-F)? salts include Ox-Li+(ABA-F), m-Li+(ABA-F), and BF3—Li+(ABA-F)?. These purified Li+(ABA-F)? salts provide the benefits of increased battery thermal safety without loss of electrochemical performance.

Abstract: The present disclosure provides c-Met antibody drug conjugates (ADCs), including compositions and methods of using such ADCs.

Abstract: Method and apparatus for an improved exercise machine for specifically exercising the wrist and forearm muscles of a user. The exercise machine includes a rectangular shaped framework having left and right side vertical frame members along with upper and lower connecting cross members mounted on a pair of left and right support legs wherein a generally rectangular framework is formed. A rotatable vertically adjustable exercise bar is positioned forwardly on left and right U-shaped brackets so that the rotatable exercise bar is height adjustable using left and right vertical adjustments means. The forwardly extending rotatable exercise bar is disposed in a spaced away manner in front of the machine so as to be comfortably positioned for use by a user standing in front of the machine.

Abstract: The present invention relates to antibodies specifically binding PSMA or PSMA and CD3, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

Abstract: An apparatus (100) for metered dispensing of a liquid from a container (3) and a spray applicator having the apparatus (100). The apparatus (100) comprises a base body (5) and a nozzle body (16) having an outlet nozzle. The nozzle body (16) is mounted so as to be displaceable relative to the base body (5) from a dispensing to a clamping position. The apparatus (100) comprises a reset spring (14) for moving the nozzle body (16) from the clamping to the dispensing position. The nozzle body (16) and the valve body form a burst chamber (19). By pressure on the trigger mechanism (26), the locking of the valve body (10) is triggered and the spray burst spring (7) presses the valve body (10) in the nozzle direction. A non-return valve is arranged upstream in the valve body. The spray burst chamber is connected to the outlet nozzle.

Abstract: A paper based overlay is provided. The overlay has a paper impregnated with a resin composition having an acrylic resin having a glass transition temperature in a range of from about ?20° C. to about 40° C. and a resin content from about 15 to about 35 wt. % based on the weight of the overlay. The acrylic composition may include wax in the amount of about 0.005 to about 3.5 wt. % based on the weight of the resin composition. A method of producing the overlay is also provided. The overlay is highly water and abrasion resistant with low volatile content.

Abstract: Active comfort controlled bedding systems and processes of operating the bedding systems generally include a variable firmness control. The active comfort controlled bedding system can include a control unit in electrical communication with a signal generating layer configured to generate heat and alter a firmness property of at least one viscoelastic foam layer, wherein the amount of heat is based on a decrease of the glass transition temperature as a function of the percentage of humidity in the environment. In other embodiments, the bedding system is provided with at least one foam layer comprising a phase change material stratified in a foam structure of the at least one foam layer; and the at least one foam layer is heated to a temperature greater than a melt temperature of the paraffin wax to soften the at least one foam layer. In other embodiments, ambient humidity conditions can be changed.

Abstract: Bedding components generally include a desiccant applied or infused into a selected bedding component. The desiccant can be microencapsulated, applied as a topical solution, and/or provided within a container including a moisture permeable membrane.

Abstract: Compressible mattress assembly packages and processes for packaging a compressible mattress assembly for a bed in a box application generally include the addition of a humidifying agent within the package. The humidifying agent provides moisture within the package, which allows the compressed mattress to effectively recover to its uncompressed state when unpackaged with minimal or no defects.

Abstract: The present disclosure provides a multi-edge saw blade for use with an oscillating tool that provides multiple cutting edges that can be used sequentially as each cutting edge becomes worn-out or damaged. The multi-edge saw blade includes a first row of cutting teeth arranged across its distal edge and a row of perforations situated across the distal end of the blade and spaced a distance behind the first row of cutting teeth. In some aspects, the multi-edge saw blade further includes at least one additional row of perforations, each situated a spaced distance behind the row of perforations before it. Responsive to a twisting force applied orthogonally to the plane of the blade, each blade edge can be removed from the blade to reveal a fresh row of cutting teeth. The multi-edge saw blade further includes an attachment socket on its proximate end.

Abstract: The present disclosure provides c-Met antibody drug conjugates (ADCs), including compositions and methods of using such ADCs.

Abstract: Multilayered mattress assemblies include at least one elongated elastic wrap compressively looped about at least two layers of the mattress assembly to maintain the at least two layers in a fixed relationship relative to one another.

Abstract: A test and measurement machine learning model development system includes a user interface, one or more ports to allow the system to connect to one or more data sources, one or more memories, and one or more processors configured to execute code to cause the one or more processors to: display on the user interface one or more application user interfaces, the application user interfaces to allow a user to provide user inputs; use and application programming interface to configure the system based on the user inputs; receive data from the one or more data sources; apply one or more modules from a library of signal processing and feature extraction modules to the data to produce training data; apply one or more machine learning models to the training data; provide monitoring of the one or more machine learning models; and save the one or more machine learning models to at least one of the one or more memories.

Abstract: A vision-cued random-access LIDAR system and method which determines the location and/or navigation path of a moving platform. A vision system on a moving platform identifies a region of interest. The system classifies objects within the region of interest, and directs random-access LIDAR to ping one or more of the classified objects. The platform is located in three dimensions using data from the vision system and LIDAR. The steps of classifying, directing, and locating are preferably performed continuously while the platform is moving and/or the vision system's field-of-view (FOV) is changing. Objects are preferably classified using at least one smart-vision algorithm, such as a machine-learning algorithm.

Abstract: A test and measurement system includes a machine learning system configured to communicate with a test automation system, a user interface configured to allow a user to provide one or more user inputs and to provide results to the user, and one or more processors, the one or more processors configured to execute code that causes the one or more processors to receive one or more user inputs through the user interface, the one or more user inputs at least identifying a selected machine learning system configuration to be used to configure the machine learning system, receive a waveform created by operation of a device under test, apply the configured machine learning system to analyze the waveform, and provide an output of predicted metadata about the waveform.

Abstract: The present disclosure provides c-Met antibody drug conjugates (ADCs), including compositions and methods of using such ADCs.

Abstract: A fifth wheel lubricant applicator tool, kit, and method of use are disclosed. The lubricant applicator tool comprises a handle portion and an operative portion. The handle portion has a first width and a defined length. The operative portion extends out from the defined length of the handle portion such that a second width of the operative portion remains less than a length of the lubricant applicator tool. The operative portion comprises a working edge equipped with a plurality of indentations that are identical and evenly spaced. The width and the height of each of the plurality of indentations permits an application of a lubricant in parallel beads, each spaced apart from adjacent beads by a defined distance that is substantially same as a distance between two adjacent indentations.

Abstract: Described herein are fog harvesters having a vertical wire array and systems thereof. The fog harvesters described herein can be used to harvest liquid from the air, such as from fog. The fog harvesters can, in some aspects, have improved performance in one or more aspects as compared to fog harvesters having a mesh design.