Abstract: A continuous process is provided for preparing a solid gel resin selected from resorcinol-formaldehyde gel resins, phenol-formaldehyde gel resins, and phenol-resorcinol-formaldehyde gel resins, using an extruder having at least one feed zone with a first temperature and at least one reaction zone with a second temperature that is higher than the first temperature. The process comprises steps of adding ingredients to the extruder at the feed zone, mixing the ingredients under heat to effectuate reaction between the ingredients to produce a liquid product exiting the extruder, and converting the liquid product exiting the extruder to the solid gel resin. A solid gel resin produced by the continuous process is also provided.

Abstract: The present disclosure provides antibody drug conjugates that bind human cMET, their methods of making, and their uses to treat patients having cancer.

Abstract: A sodium ion battery comprises a cathode having a porous redox active metal-organic framework material. The battery can be an organic electrolyte sodium ion battery wherein the electrolyte comprises a sodium salt dissolved in an organic solvent or mixture of organic solvents. Alternatively, the battery can comprise an aqueous sodium ion battery wherein the electrolyte comprises a sodium salt dissolved in an aqueous solvent. Battery performance is especially related to electrolyte and binder selection.

Abstract: A sodium ion battery comprises a cathode having a porous redox active metal-organic framework material. The battery can be an organic electrolyte sodium ion battery wherein the electrolyte comprises a sodium salt dissolved in an organic solvent or mixture of organic solvents. Alternatively, the battery can comprise an aqueous sodium ion battery wherein the electrolyte comprises a sodium salt dissolved in an aqueous solvent. Battery performance is especially related to electrolyte and binder selection.

Abstract: Nonaqueous redox flow batteries (RFB) hold the potential for high energy density grid scale storage, though are often limited by the solubility of the redox-active species in their electrolytes. A systematic approach enables an increase the concentration of redox-active species in electrolytes for nonaqueous RFB, starting from a metal-coordination-cation-based ionic liquid. As an example, starting with an ionic liquid consisting of a metal coordination cation (MetIL), ferrocene-containing ligands and iodide anions can be substituted into the original MetIL structure, enabling a nearly 4× increase in capacity compared to original MetIL structure. Application of this strategy to other chemistries, optimizing electrolyte melting point and conductivity could yield >10 M redox-active electrons.

Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).

Abstract: A document product includes a web having a transverse splice therein. A mask is formed near the splice and is subsequently used for automatically rejecting a spliced document.

Abstract: A computing device performance monitor may be configured to collect performance metric information regarding one or more monitored computing devices, and may assign condition point values to each metric. The performance monitor may generate a total of the condition point values, and use the total to determine an appropriate response.

Abstract: A method to reduce corrosion rates of materials at high temperatures may include heating a mixture and applying the heated mixture to a material to be rendered thermodynamically noble. The mixture may include carbon monoxide and carbon dioxide and the material rendered thermodynamically noble may include copper or other material having similar physical properties. The copper or other similar material may be applied to a structural material and provide a surface interfacing with the mixture of carbon monoxide and carbon dioxide to prevent corrosion of the structural material. In some cases, the structural material may form a heat exchanger defining passageways for a working fluid of a power system and/or may form other passageways of the power system. The copper may be applied to the passageways as a protective coating and then made thermodynamically noble at high temperatures after interactions with the mixture of carbon monoxide and carbon dioxide.

Abstract: The invention generally relates to systems, methods, and devices for ex vivo organ care. More particularly, in various embodiments, the invention relates to caring for a liver ex vivo at physiologic or near-physiologic conditions.

Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).

Abstract: Embodiments of the present invention include a holster with a first holster layer of leather configured as a holster backer for wear adjacent to a user's body, the first holster layer attached to a second holster layer of Kydex, the second holster layer molded to fit over a portion of a handgun, the holster further having a trigger guard retention formed from the material of the second holster layer, the retention having an integral pocket that is capable of interference fit with a handgun.

Abstract: Provided are antibody drug conjugates that bind PRLR, in particular human PRLR, their methods of making, and uses thereof.

Abstract: An interactive user interface in a point of care application within an integrated service system automatically identifies gaps in care and generates a provider workflow for closing the gaps. The integrated service system is driven by healthcare analytics and an integrated messaging system to managing gaps in healthcare and healthcare risk and quality measures. Core analytics that identify the corresponding gaps in care are performed in a rules based analytics engines coupled to a data store in healthcare information and to the interactive user interface.

Abstract: Nonaqueous redox flow batteries (RFB) hold the potential for high energy density grid scale storage, though are often limited by the solubility of the redox-active species in their electrolytes. A systematic approach enables an increase the concentration of redox-active species in electrolytes for nonaqueous RFB, starting from a metal-coordination-cation-based ionic liquid. As an example, starting with an ionic liquid consisting of a metal coordination cation (MetIL), ferrocene-containing ligands and iodide anions can be substituted into the original MetIL structure, enabling a nearly 4× increase in capacity compared to original MetIL structure. Application of this strategy to other chemistries, optimizing electrolyte melting point and conductivity could yield >10 M redox-active electrons.

Abstract: A pressure-sensing device is disclosed, which includes a pressure sensor pad. The pressure sensor pad includes a first planar substrate, a second planar substrate, first signal lines, second signal lines, a plurality of rows of first sensor components, and a plurality of columns of second sensor components. The first signal lines and the rows of first sensor components are formed on the first planar substrate, and each row of the first sensor components is connected to a corresponding one of the first signal lines. The second planar substrate is disposed opposite to the first planar substrate. The second signal lines and the columns of second sensor components are formed on the second planar substrate, and each column of the second sensor components is connected to a corresponding one of the second signal lines, where the second sensor components face the first sensor components respectively.

Abstract: Provided are antibody drug conjugates that bind PRLR, in particular human PRLR, their methods of making, and uses thereof.

Abstract: Disclosed herein are systems and methods for converting physical input signals into bitstreams using syntax trees regardless of the physical input signal's protocol. Using declarative language definitions within a protocol declaration, a test and measurement system can compile a syntax tree that automatically translates the input data into a proper bitstream output. The declarative language definitions within the protocol declaration allow custom or standard protocol rules to be written for multiple or arbitrary input protocols without writing unsafe functions, having to access memory, or debugging more complex language codes.

Abstract: The invention generally relates to systems, methods, and devices for ex vivo organ care. More particularly, in various embodiments, the invention relates to caring for a liver ex vivo at physiologic or near-physiologic conditions.

Abstract: The present disclosure provides antibody drug conjugates that bind human cMET, their methods of making, and their uses to treat patients having cancer.