Abstract: Inverse temperature crystallization processes are provided to produce perovskite single crystals (PSCs), as well as surface passivation techniques for producing stabilizing the PSCs in the bulk region. Stable hybrid perovskite material include a bulk region comprising a single crystal perovskite material having a first bandgap and a smooth perovskite surface layer having a second bandgap greater than the first bandgap. Devices for detection and energy conversion are also contemplated, including for spectroscopic photon and elementary particle detection, such as radiation detectors. Crystallization chambers for forming the PSCs are also provided.

Abstract: A clamshell half of a split ring mechanical seal face assembly comprises a split seal ring half having circumferential and proximal surfaces that are seated against corresponding radial and axial support surfaces of a holder half. At least one extending member extends from a hole in the proximal surface to an arcuate slot in the axial support surface, or vice-versa, and thereby radially constrains the split seal ring half to remain unitized with the holder half during clamshell assembly, while permitting rotation of the split seal ring half about a shaft axis over a limited range, which in embodiments is between 2 degrees and 20 degrees. Embodiments further include a secondary seal between the holder half and split seal ring half that frictionally resists displacement of the split seal ring half.

Abstract: Embodiments of the disclosure include methods and compositions related to treatment or prevention of cancer therapy-induced tissue inflammation, dermatitis, and/or scarring. In particular embodiments one or more proton pump inhibitors are provided to an individual before, during, and/or after receiving anticancer therapy. In some embodiments one or more proton pump inhibitors are provided to an individual before, during, and/or after having a health conditions, allergies, genetic factors and/or exposure to one or more irritants.

Abstract: Methods and apparatus that mix a plurality of individual capture reagents for the diagnostic assays are described herein. In an embodiment, a system for optically analyzing a patient sample includes an automated immunochemistry analyzer storing a plurality of capture reagents and a plurality of paramagnetic particles, a user interface configured to allow a selection of a combination of two or more of the capture reagents, and a logic implementer configured to cause the automated immunochemistry analyzer to (i) mix together each capture reagent of the combination of two or more of the capture reagents; (ii) bind the mixture of the combination of two or more of the capture reagents to the paramagnetic particles; (iii) bind the patient sample to the bound mixture of the combination of two or more of the capture reagents; and (iv) optically analyze the patient sample.

Abstract: One embodiment is an apparatus comprising an aircraft and an aerial network communications system associated with the aircraft. The network communications system may comprise an antenna physically connected to an outside surface of the aircraft; and a transceiver electrically connected to the antenna. The aerial network communications system receives signals from and transmits signals to an unmanned aerial vehicle (“UAV”) via a communications network comprising a control station and a plurality of airborne network nodes.

Abstract: Methods and systems for control of solid phase peptide synthesis are generally described. Control of solid phase peptide synthesis involves the use of feedback from one or more reactions and/or processes (e.g., reagent removal) taking place in the solid phase peptide synthesis system. In some embodiments, a detector may detect one or more fluids flowing across a detection zone of a solid phase peptide synthesis system and one or more signals may be generated corresponding to the fluid(s). For instance, an electromagnetic radiation detector positioned downstream of a reactor may detect a fluid exiting the reactor after a deprotection reactor and produce a signal(s). In some embodiments, based at least in part on information derived from the signal(s), a parameter of the system may be modulated prior to and/or during one or more subsequent reactions and/or processes taking place in the solid phase peptide synthesis system.

Abstract: The present invention relates to compounds of formula (I), and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity: wherein X, R1, R2, and n are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.

Abstract: A medical device is described having a handle, a shaft coupled to the handle and an end effector coupled to the shaft. In one embodiment, the device includes an ultrasonic transducer and is arranged so that ultrasonic or electrical energy can be delivered to a vessel or tissue to be treated. Various novel sensing circuits are described to allow a measure of the drive signal to be measured and fed back to a controller. An active fuse circuit is also described for protecting one or more batteries of the device from an over-current situation.

Abstract: Embodiments provide a spacecraft airlock system. Embodiments provide a method and apparatus for attaching space exposed payloads to a space station. The spacecraft airlock system provides a defined volume of space payload to the international space station. The airlock further includes a means of attaching to a space station, a closed structure attached to said means, said means of attaching is capable of robotic manipulation, and a cooling system for cooling payload components within said closed structure.

Abstract: Systems and methods are described for recognizing and responding to commands. A system may receive voice data and determine an intended command. The system may then determine a position and viewpoint orientation of the user to be able to determine one or more digital assets associated with the user. The system may then determine a current state associated with each digital asset of the one or more digital assets to be able to determine at least one digital asset that is configured to process the command. The system can then apply the command to at least a first digital asset of the at least one digital asset that is configured to process the command.

Abstract: Representative embodiments provide a composition for printing a liquid or gel separator utilized to separate and space apart first and second conductors or electrodes of an energy storage device, such as a battery or a supercapacitor. A representative composition comprises a plurality of particles, typically having a size (in any dimension) between about 0.5 to about 50 microns; a first, ionic liquid electrolyte; and a polymer or polymeric precursor. In another representative embodiment, the plurality of particles comprise diatoms, diatomaceous frustules, and/or diatomaceous fragments or remains. Another representative embodiment further comprises a second electrolyte different from the first electrolyte; the plurality of particles are comprised of silicate glass; the first and second electrolytes comprise zinc tetrafluoroborate salt in 1-ethyl-3-methylimidalzolium tetrafluoroborate ionic liquid; and the polymer comprises polyvinyl alcohol (“PVA”) or polyvinylidene fluoride (“PVFD”).

Abstract: In some examples, an active stylus may include a main portion and a top portion. The main portion may include a dry chamber used to store a battery. The top portion may include a wet chamber to store spare nibs. The wet chamber may be accessed to replace a damaged nib with a spare nib. When the top portion is fully mated with the main portion of the stylus, turning the top portion, in a first direction, relative to the main portion until the detent is reached and pulling the top portion from the main portion enables access to the wet chamber. Turning the top portion of the active stylus, in the first direction, relative to the main portion past the detent, until the top portion detaches from the main portion, enables access to the dry chamber.

Abstract: Systems and methods for towing, hitching, and connecting devices are described. An autonomous guided vehicle includes an automated hitch capable of connecting to a variety of types of containers.

Abstract: A method is provided for generating and revising map geometry based on a received image and probe data. A method may include: receiving probe data from a first period of time, where the probe data from a first period of time is from a plurality of probes within a predefined geographic region; generating a first image of the predefined geographic region based on the probe data from the first period of time; receiving probe data from a second period of time different from the first period of time, where the probe data from the second period of time is from a plurality of probes within the predefined geographic region; generating a second image based on the probe data from the second period of time; comparing the first image to the second image; and generating a revised route geometry based on changes detected between the first image and the second image.

Abstract: A multi-endpoint event graph is used to detect malware based on malicious software moving through a network.

Abstract: A premixer for a gas turbine combustor includes a centerbody, a swirler assembly, and a mixing duct. The swirler assembly includes an inner swirler with vanes that rotate air in a first direction and an outer swirler with vanes that rotate air in an opposite direction. The inner swirler vanes and the outer swirler vanes are separated by an annular splitter. The outer swirler vanes define an outlet plane, and the inner swirler vanes each have a trailing edge that is disposed at an acute angle relative to the outlet plane. In one aspect, the inner swirler is axially offset from the outer swirler. The mixing duct may also define fuel passages that deliver fuel to fuel outlets on the downstream end of the mixing duct. The premixer is designed for operation on gaseous fuel or liquid fuel.

Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.

Abstract: A novel maize variety designated X13N205 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X13N205 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13N205 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X13N205, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13N205 are provided. Methods for producing maize varieties derived from maize variety X13N205 and methods of using maize variety X13N205 are disclosed.

Abstract: Embodiments provide a spacecraft airlock system. Embodiments provide a method and apparatus for attaching space exposed payloads to a space station.