Patents by Inventor Mark L. Mathis

Mark L. Mathis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200155165
    Abstract: A system for treating a genetically associated chronic obstructive pulmonary disease. The system includes a coil implant, wherein the coil implant is configured to increase tension of a lung having alveolar damage caused by a genetic disorder and thereby improve breathing function of the lung. The system includes a delivery system configured to deliver the coil implant into an airway of the lung, wherein the delivery system comprises a cartridge configured to retain the coil implant in a straight configuration. The coil implant is configured to recover to a non-straight, pre-determined shape upon deployment within the airway the lung of the patient.
    Type: Application
    Filed: December 10, 2019
    Publication date: May 21, 2020
    Applicant: PneumRx, Inc.
    Inventors: Mark L. Mathis, Kara Andersen Reiter
  • Patent number: 10543053
    Abstract: A container for a medical device having a housing defining a cavity for receiving a device, such as a lung volume reduction coil, is disclosed. In some embodiments, the container includes a coupling zone external to the cavity, an exit aperture between the cavity and the coupling zone, and a bearing surface located within the cavity, the bearing surface, exit aperture and coupling zone defining an exit path along which the device can be moved for deployment from the container. The bearing surface is spaced from the exit aperture and arranged, together with the coupling zone, such that the exit path is substantially straight. In some embodiments, the cavity may be approximately cylindrical, and the bearing surface, the exit aperture, and the coupling zone are aligned such that the exit path extends in a direction that is substantially tangential to the cavity.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: January 28, 2020
    Assignee: PneumRx, Inc.
    Inventors: David Lehrberg, Jeffrey W. Etter, Mark L. Mathis, Verna Rodriguez
  • Patent number: 10537334
    Abstract: A method for treating a genetically associated chronic obstructive pulmonary disease. At least one implant is advanced into an airway of a lung having a genetically associated chronic obstructive pulmonary disease. The at least one implant is delivered into the lung to increase tension of the lung and thereby improve breathing function of the lung.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: January 21, 2020
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, Kara Andersen Reiter
  • Publication number: 20200008943
    Abstract: An anchor anchors a therapeutic device having an elongated body within a body lumen. The anchor includes a fixation member carried on the device which is adjustable from a first configuration that permits placement of the device in the body lumen to a second configuration that anchors the device within the body lumen. The anchor further includes a lock that locks the fixation member in the second configuration. The fixation member may be locked in any one of a plurality of intermediate points between the first configuration and a maximum second configuration.
    Type: Application
    Filed: September 19, 2019
    Publication date: January 9, 2020
    Inventors: Mark L. MATHIS, Leonard KOWALSKY, David G. REUTER, Cruz BEESON
  • Publication number: 20190350708
    Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 21, 2019
    Inventors: Mark L. MATHIS, Gregory D. NIEMINEN, Nathan ARONSON, Garrett R. BEGET
  • Publication number: 20190336290
    Abstract: Devices for treating mitral valve regurgitation, including a distal expandable anchor, a proximal expandable anchor, and a fixed length connecting member extending from the proximal expandable anchor to the distal expandable anchor, where at least one of the proximal and distal anchors includes first and second arm segments that extend from one end of the device toward the connecting member and the other anchor when in a collapsed delivery configuration, and where the at least one of the proximal and distal anchors that comprises the first and second arm segments has an expanded configuration in which the first and second arm segments extend radially outwardly such that the first and second arm segments extend away from one another toward the connector, and meet one another at a location axially spaced from the end of the device.
    Type: Application
    Filed: June 24, 2019
    Publication date: November 7, 2019
    Inventors: Mark L. MATHIS, Gregory D. NIEMINEN, David G. REUTER
  • Publication number: 20190328400
    Abstract: Pulmonary treatment devices, systems and methods of use are provided which take into account the vast tissue damage of advanced COPD sufferers and provide treatments designed specifically to treat the particularly compromised lung tissues that are present in these patients. These treatments reduce trapped air volume, tension lung tissue and enhance lung elastic recoil. A variety of embodiments are provided, including pulmonary treatment devices that move portions of lung tissue around a rotational axis into a torqued configuration, anchoring such tissue in place for improved breathing mechanics.
    Type: Application
    Filed: June 18, 2019
    Publication date: October 31, 2019
    Applicant: Free Flow Medical, Inc.
    Inventors: Mark L. Mathis, Michael W. Lau, Kevin Mitz, Ryan Braxtan
  • Patent number: 10456257
    Abstract: An anchor anchors a therapeutic device having an elongated body within a body lumen. The anchor includes a fixation member carried on the device which is adjustable from a first configuration that permits placement of the device in the body lumen to a second configuration that anchors the device within the body lumen. The anchor further includes a lock that locks the fixation member in the second configuration. The fixation member may be locked in any one of a plurality of intermediate points between the first configuration and a maximum second configuration.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: October 29, 2019
    Assignee: Cardiac Dimensions Pty. Ltd.
    Inventors: Mark L. Mathis, Leonard Kowalsky, David G. Reuter, Cruz Beeson
  • Patent number: 10456258
    Abstract: An anchor anchors a therapeutic device having an elongated body within a body lumen. The anchor includes a fixation member carried on the device which is adjustable from a first configuration that permits placement of the device in the body lumen to a second configuration that anchors the device within the body lumen. The anchor further includes a lock that locks the fixation member in the second configuration. The fixation member may be locked in any one of a plurality of intermediate points between the first configuration and a maximum second configuration.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: October 29, 2019
    Assignee: Cardiac Dimensions Pty. Ltd.
    Inventors: Mark L. Mathis, Leonard Kowalsky, David G. Reuter, Cruz Beeson
  • Publication number: 20190307458
    Abstract: Pulmonary treatment devices, systems and methods of use are provided which take into account the vast tissue damage of advanced COPD sufferers and provide treatments designed specifically to treat the particularly compromised lung tissues that are present in these patients. These treatments reduce trapped air volume, tension lung tissue and enhance lung elastic recoil. A variety of embodiments are provided, including pulmonary treatment devices that move portions of lung tissue around a rotational axis into a torqued configuration, anchoring such tissue in place for improved breathing mechanics.
    Type: Application
    Filed: June 18, 2019
    Publication date: October 10, 2019
    Applicant: Free Flow Medical, Inc.
    Inventors: Mark L. Mathis, Michael W. Lau, Kevin Mitz, Ryan Braxtan
  • Publication number: 20190216466
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Application
    Filed: March 25, 2019
    Publication date: July 18, 2019
    Applicant: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Patrick Wu
  • Publication number: 20190192163
    Abstract: A device for enhancing the breathing efficiency of a patient is provided. The implantable device may include a deployed configuration with one or more helical sections with proximal end in a stand-off proximal end configuration. The stand-off proximal end configuration may reduce migration of the deployed device and may preserve implant tissue compression. Alternative configurations may include two or more helical sections with a transition section disposed between the two or more helical sections. A device may include a right-handed helical section and a left-handed helical section and the transition section comprises a switchback transition section. The switchback section may provide greater control of the device during deployment by limiting recoiling forces of a device comprising a spring material. The deployed device may compress the lung to increase a gas filling resistance of the compressed portion of the lung, and/or increase tension and elastic recoil in other portions of the lung.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 27, 2019
    Inventors: Jaime Vasquez, Mark L. Mathis, Timothy Machold, Andrew Stein
  • Patent number: 10327900
    Abstract: Devices for treating mitral valve regurgitation, including a distal expandable anchor, a proximal expandable anchor, and a fixed length connecting member extending from the proximal expandable anchor to the distal expandable anchor, where at least one of the proximal and distal anchors includes first and second arm segments that extend from one end of the device toward the connecting member and the other anchor when in a collapsed delivery configuration, and where the at least one of the proximal and distal anchors that comprises the first and second arm segments has an expanded configuration in which the first and second arm segments extend radially outwardly such that the first and second arm segments extend away from one another toward the connector, and meet one another at a location axially spaced from the end of the device.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: June 25, 2019
    Assignee: Cardiac Dimensions Pty. Ltd.
    Inventors: Mark L. Mathis, Gregory D. Nieminen, David G. Reuter
  • Publication number: 20190159799
    Abstract: This invention relates to device, systems, kits and methods that enable selective dissection of lung tissue to remove diseased tissue from healthy tissue without damaging blood vessels or airways. The invention and methods enable minimally invasive lung surgery procedures by providing a device and method to perform automated dissection that discriminates against traumatizing critical lung tissue.
    Type: Application
    Filed: February 15, 2019
    Publication date: May 30, 2019
    Inventors: Mark L. Mathis, Amelia Lasser, David Lehrberg
  • Publication number: 20190150936
    Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
    Type: Application
    Filed: January 24, 2019
    Publication date: May 23, 2019
    Applicant: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Nathan Aronson, Patrick Wu
  • Patent number: 10285707
    Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: May 14, 2019
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Patrick Wu
  • Patent number: 10226257
    Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: March 12, 2019
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, David Thompson, Nathan Aronson, Patrick Wu
  • Patent number: 10188397
    Abstract: A device for enhancing the breathing efficiency of a patient is provided. The implantable device may include a deployed configuration with one or more helical sections with proximal end in a stand-off proximal end configuration. The stand-off proximal end configuration may reduce migration of the deployed device and may preserve implant tissue compression. Alternative configurations may include two or more helical sections with a transition section disposed between the two or more helical sections. A device may include a right-handed helical section and a left-handed helical section and the transition section comprises a switchback transition section. The switchback section may provide greater control of the device during deployment by limiting recoiling forces of a device comprising a spring material. The deployed device may compress the lung to increase a gas filling resistance of the compressed portion of the lung, and/or increase tension and elastic recoil in other portions of the lung.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: January 29, 2019
    Assignee: PneumRx, Inc.
    Inventors: Jaime Vasquez, Mark L. Mathis, Timothy Machold, Andrew Stein
  • Patent number: 10188398
    Abstract: Elongate implant structures can be introduced into an airway system to a target airway axial region, often to apply lateral bending and/or compression forces against the lung tissue from within the airways for an extended period of time. Structures or features of the implants may inhibit tissue reactions that might otherwise allow portions of the device to eventually traverse through the wall of the airway. The devices may enhance the area bearing laterally on the tissue of a surrounding airway lumen wall. Embodiments may have features which increase the device friction with the airway to allow the device to grip the surrounding airway as the device is deployed. An appropriate adhesive may be introduced around the device in the lung. Hydrophilic material may inhibit biofilm formation, or features which induce some tissue ingrowth (stimulation of tissue growth) may enhance implanted device supported.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: January 29, 2019
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, Patrick Wu, David Lehrberg, Jaime Vasquez, Erin McGurk, Ronald Dieck, Andrew Stein
  • Patent number: 10166041
    Abstract: This invention relates to device, systems, kits and methods that enable selective dissection of lung tissue to remove diseased tissue from healthy tissue without damaging blood vessels or airways. The invention and methods enable minimally invasive lung surgery procedures by providing a device and method to perform automated dissection that discriminates against traumatizing critical lung tissue.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: January 1, 2019
    Assignee: PneumRx, Inc.
    Inventors: Mark L. Mathis, Amelia Lasser, David Lehrberg