Abstract: Blockade of the CD47/SIRPa pathway depletes cancer cells. This anti-cancer activity is enhanced when macrophage stimulating agents are used in combination with the CD47 blockade drug. This anti-cancer combination therapy is particularly effective when the CD47 blockade drug is SIRPaFc.

Abstract: Multi-filament microcables are used in place of the traditional monofilament wires as the constituent elements of a woven or braided band. This enhances the function and manufacturability of such bands for various applications, such as orthopaedic applications including sternotomy closures.

Abstract: A laser receiver comprising a sensor; a first amplifier operatively connected to the sensor comprising a first gate, a first source and a first drain; a first subcircuit operatively connected between the first drain and the first gate comprising a first resistor, a first inductor and a decoupling capacitor configured to allow the first amplifier bias to be established by the at least one first biasing resistor; the impedance of the first gate being sufficient such that only a small proportion of the current from the sensor passes into the first gate; an inductor connecting the first gate to the at least one biasing resistor with high impedance at the receiver operating frequency; a second amplifier comprising a second gate operatively connected to the first drain; and an output configured to be operatively connected to a processing unit and a display unit configured to displaying output and method thereof.

Abstract: A method includes causing a control cluster to be included in a user interface and overlapping with an interactive virtual environment. The control cluster includes a first icon area, a second icon area, and a trigger icon area. The method further includes causing a first image to be displayed in the first icon area and a second image to be displayed in the second icon area. The method additionally includes causing a copy of the first image to be displayed in the trigger icon area or a copy of the second image to be displayed in the trigger icon area. The method also includes causing a readiness level of a game play feature to change, and causing the copy of the first image displayed in the trigger icon area or the copy of the second image displayed in the trigger icon area to be replaced with a trigger image.

Abstract: An engine cylinder head comprising an internal metal structure formed from a metal material and an external polymer composite structure formed from a polymer composite material, wherein the external polymer composite structure at least partially surrounds the internal metal structure.

Abstract: An engine cylinder head includes an internal metal structure formed from a metal material, at least a portion of which includes a thermal coating and an external polymer composite structure formed from a polymer composite material, wherein the external polymer composite structure at least partially surrounds the internal metal structure.

Abstract: A system and methods for routing condensate collected in a heat exchanger reservoir to either an air intake system or a position in the engine exhaust based on the type of contaminate in the condensate and operating parameters of the engine or the catalyst are described. In one particular example, condensate is routed to a first position along the engine air intake system in a first mode of operation, and a second position upstream of the catalyst along the engine exhaust in a second mode of operation, and a third position downstream of the catalyst along the engine exhaust in a third mode of operation. When substantially no contaminates are detected, the condensate may be routed into the engine exhaust upstream of the catalyst in order to cool the catalyst.

Abstract: A tubular member (1) with a relative rough (1.5-10 ?m) inner surface (5) coated solid lubricating film (10) which is transformed into a substantially viscous rubbery viscoelasto-plastic phase at temperatures in a range between 50° C. and 110° C. is expanded by moving an expansion member (24) with a relatively smooth outer surface (roughness <1.5 ?m) therethrough, such that during expansion a viscous viscoelastoplastic substantially rubbery lubricating film (44) is generated between the tubular member (1) and the expansion mandrel (24), which film remains bonded to the rough inner surface (5) of the expanded tubular (1), but does not stick to the relatively hot and smooth expansion member (24).

Abstract: A paperboard packaging material includes a top layer including non-wood fibers blended with wood fibers, wherein the non-wood fibers are 5% to 100% of the top layer; a back layer including non-wood fibers blended with wood fibers, wherein the non-wood fibers are 5% to 100% of the back layer; and a middle layer disposed between the top and back layers. The middle layer can include 5% to 100% non-wood filler fibers. The non-wood filler fibers can be wheat straw. The non-wood fibers can be bamboo.

Abstract: Systems and methods for automatic repair, replacement, and/or configuration of various network devices within a communications network are disclosed. The system may receive indication of a failed network device and automatically perform diagnostic on the network device to determine any problems associated with the hardware and/or software components within the network device. Subsequently one or more repair, replacement, and/or configuration procedures may be automatically initiated in an attempt to resolve the problems and restore the failed network device.

Abstract: Facilities, methods, and systems to produce therapeutic protein(s) can include collecting eggs from transgenic avian in a production unit in a building; transferring the eggs to a harvesting unit in the building; and harvesting egg white or egg yolk from the eggs in the harvesting unit.

Abstract: An engine cylinder head includes an internal metal structure formed from a metal material, at least a portion of which includes a thermal coating and an external polymer composite structure formed from a polymer composite material, wherein the external polymer composite structure at least partially surrounds the internal metal structure.

Abstract: A pair of smart glasses having interfering light filtering includes a glasses frame defining a horizontal view path and a semi-transparent display supported on the glasses frame and positioned in the horizontal view path. A projection mechanism is supported on the glasses frame and has a projection lens positioned above the horizontal view path. The projection mechanism is configured for projecting virtual content on the semi-transparent display, with an outer surface of the projection lens facing a rear facing surface of the semi-transparent display. A semi-transparent polarized shield is supported on the glasses frame and is positioned below the horizontal view path, with an inner surface of the semi-transparent polarized shield facing the outer surface of the projection lens. The semi-transparent polarized shield positioned to filter interfering light passing through the semi-transparent polarized shield and toward the projection lens.

Abstract: A cam carrier assembly includes a body made of a material lighter than aluminum. The body has a first side operably coupled with a cylinder head and a second side having bearing surfaces with bearing inserts. The bearing inserts support the camshaft. A series of apertures extend between the first and second sides of the body. Lobes of the camshaft operably couple with the valves of the cylinder head through the series of apertures extending between the first and second sides of the body.

Abstract: Systems and methods for automatic repair, replacement, and/or configuration of various network devices within a communications network are disclosed. The system may receive indication of a failed network device and automatically perform diagnostic on the network device to determine any problems associated with the hardware and/or software components within the network device. Subsequently one or more repair, replacement, and/or configuration procedures may be automatically initiated in an attempt to resolve the problems and restore the failed network device.

Abstract: A valve cover module includes a unitary cover and carrier made of a carbon fiber composite. The unitary cover and carrier has a lower side with a peripheral edge for attaching to a cylinder head. The lower side of the unitary cover and carrier also has a series of cavities interconnected with aligned apertures defining bearing surfaces. A plurality of cam lobes is disposed in the series of cavities. Also, the valve cover module includes a camshaft rotatable on the bearing surfaces and extending through the aligned apertures to couple with the cam lobes.

Abstract: Systems for defining an internally threaded bore in a composite material component include one or more thread forming tools each defining a thread forming portion and a locating fixture configured to hold the one or more thread forming tools in a predetermined configuration defining a pattern of internally threaded bores to be provided in the composite material component. The thread forming portions include a plurality of thread forming surfaces each defining a pitch, a crest fillet radius, and a root fillet radius, and define internally threaded bores having an interior helical thread defining a plurality of full crest radii and a plurality of full root radii. A component forming fixture is provided for abutting the locating fixture whereby the one or more thread forming tools are held in an interior of the forming fixture. Methods for forming composite material components having internally threaded bores using the described systems are described.

Abstract: A cam carrier assembly includes a body made of a material lighter than aluminum. The body has a first side operably coupled with a cylinder head and a second side having bearing surfaces with bearing inserts. The bearing inserts support the camshaft. A series of apertures extend between the first and second sides of the body. Lobes of the camshaft operably couple with the valves of the cylinder head through the series of apertures extending between the first and second sides of the body.

Abstract: The present disclosure relates to novel crystalline salt forms of lamivudine, methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of viruses such as Human Immunodeficiency Virus (HIV) infection.

Abstract: A method is provided of creating a pipe connector including a first connector member and a second connector member, said connector members being adapted to be connected and disconnected multiple times, the method comprising: a) providing at least one of the connector members with a contact surface; b) depositing particles of a galling resistant metal on each said contact surface; c) at least partially melting the particles of the galling resistant metal by subjecting the particles to a quantity of heat; and d) allowing the molten galling resistant metal to solidify thereby forming a galling resistant metal coating which is metallurgically bonded to the contact surface. The heat may be provided in the form of radiant energy, using a laser beam.