Abstract: Compounds of formula (I) are modulators of gamma-secretase, and hence are useful in treatment of Alzheimer's disease.

Abstract: The invention enables digital music content to be downloaded to and used on a portable wireless computing device. An application running on the wireless device has been automatically adapted to parameters associated with the wireless device without end-user input (e.g. the application has been configured in dependence on the device OS and firmware, related bugs, screen size, pixel number, security models, connection handling, memory etc. This application enables an end-user to browse and search music content on a remote server using a wireless network; to download music content from that remote server using the wireless network and to playback and manage that downloaded music content. The application also includes a digital rights management system that enables unlimited legal downloads of different music tracks to the device and also enables any of those tracks stored on the device to be played so long as a subscription service has not terminated.

Abstract: A display for displaying an image to a viewer, capable of highlighting specific locations selected by a user. This display comprises: a) a punchable layer such as a foam board having a first surface and a second surface, b) an image affixed to the first surface of the punchable layer. The punchable layer and the image form a sandwich dubbed display cover which is partially transparent and is observed by a viewer located on the image side of the display cover, c) a light source illuminating the second surface of the punchable layer, d) a piercing means for enabling the user to punch at least one hole into the punchable layer, and e) a plurality of pegs equal in number to the number of holes.

Abstract: Compounds of formula I: selectively inhibit production of A?(1-42) and hence are useful in treatment or prevention of disease associated with deposition of ?-amyloid in the brain.

Abstract: A method for the sorption of a liquid or vapor phase trace contaminant from a fluid stream containing an electrically charged particulate, which comprises: providing a fluid stream comprising a liquid or vapor phase trace contaminant and an electrically charged particulate; providing an electrically conductive stationary sorbent having an electrical charge that is of the same polarity as that of the charged particulate; and contacting the fluid stream with the charged stationary sorbent, which sorbs the trace contaminant and repels the charged particulate.

Abstract: Compounds of formula I: modulate the action of gamma secretase, and hence find use in treatment of Alzheimer's disease and related conditions.

Abstract: A system for receiving and processing data includes a data processing and verification component that accepts data from a client in an electronic format and identifies therefrom data elements that can be directly verified. A risk assessment component receives data elements that have not been identified as directly verifiable and assesses a risk that the data elements are incomplete or incorrect. The risk assessment component generates risk assessment data. A decision support component receives the risk assessment data from the risk assessment component and selects appropriate actions for subsequent processing of the client data according to the assessment of risk contained in the risk assessment data.

Abstract: The present invention relates to a method for treating plastic substrates structured by means of a laser or generation of seed structures on the surface that are suitable for subsequent metallization. The substrates, after the laser structuring, are brought into contact with a process solution that is suitable for removal of the unintentional deposits that arise during the laser structuring. The treatment of the laser-structured substrates with a mixture of wetting agents and compositions that support the cleaning before metallization leads to sufficient removal of the unintentionally deposited metal seeds, without having a lasting damaging effect on the planned structured surface paths.

Abstract: An etching composition for non-conductive substrates such as polyester, polyether, polyimide, polyurethane, epoxy resin, polysulfone, polyethersulfone, polyetherimide, and polyamide, comprising a halogenide and/or nitrate of a metal selected from the group consisting of Na, Mg, Al, Si, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Ca, Zn, and combinations thereof such as FeCl3, FeCl2, TiCl3, CaCl2, CuCl2, CrCl3, ZnCl2, MgCl2, MnCl2, and Cr(NO3)3; and a related method for etching.

Abstract: A compound of formula 1, or a pharmaceutically acceptable salt thereof, wherein: X is S, O, or NH; “a” is a single bond; or “a” is a double bond and one of R3 and R4, and one of R5 and R6 are absent; R1 is H; or is selected from an alkyl group, a cycloalkyl group, a heteroaryl group, an aralkyl group, CO-alkyl, SO2-alkyl, CO2R13 and an aryl group, each of which optionally contains one or more heteroatoms, and is optionally substituted with one or more groups selected from R8 and R9; R2 is H, R8, or an alkyl group optionally substituted with one or more R8 groups; R3, R4, R5, and R6 are each independently selected from H, R8, an alkyl group and an alkenyl group, wherein said alkyl and alkenyl groups are optionally substituted with one or more R8 groups; or R3 and R4, and/or R5 and R6 together represent ?O; R7 is H, R8, NH(CH2)nR9, CO(CH2)nR9, NHCO(CH2)nR9, O(CH2)nR9, or an alkyl or phenyl group, each of which is optionally substituted with one or more groups selected from R8 and R9; R8 is OR10, NR10R11, ha

Abstract: Compounds of formula (I) modulate the activity of gamma secretase and hence find use in treatment or prevention of Alzheimer's disease and related conditions.

Abstract: An optical-fiber-network (OFN) radio-frequency identification (RFID) system for deploying and/or maintaining and/or provisioning service and/or locating faults in an OFN. The system includes a plurality of OFN components, and at least one RFID tag that includes RFID tag data that has at least one property of the OFN component associated with the RFID tag. The RFID tag data is written to and read from the RFID tags using one or more mobile RFID readers either prior to, during or after deploying the OFN components. An OFN-component-data database unit is used to store and process the RFID tag data and is automatically updated by the one or more mobile RFID readers. This allows for different maps of the OFN to be made, such as an inventory map and a maintenance map, and for the maps to be automatically updated. The OFN-RFID system allows for mobile automated operations and management of OFN components by service personnel, and provides for faster and more accurate OFN system deployment and maintenance.

Abstract: Compounds of formula I: are potent inhibitors of gamma-secretase and hence find use in treatment or prevention of diseases associated with deposition of ?-amyloid.

Abstract: A coupler device includes a hollow housing defining first and second openings, an electrical path through the housing, and a physical block including a potting material that surrounds the electrical path and fills the space between the electrical path and the housing.

Abstract: A method, apparatus, and computer instructions for processing instructions. A data dependency graph is built. The data dependency graph is analyzed for recurrences, and unpipelined instructions that lie outside of the recurrences are expanded.

Abstract: A solid food product is molded in a mold cavity and is thereafter packaged in the mold cavity. The mold cavity is formed in a sheet and includes a side wall which extends from the sheet and a bottom wall which includes an inverting portion which extends from said side wall and a central portion. The central potion of the bottom wall includes a plurality of ridges which form a decorative design. A liquid food product is introduced into the mold cavity and allowed to solidify to form a molded solid food product. The central portion of the bottom wall is thereafter pushed into the mold cavity to invert said inverting potion and to push the molded food product away from the central portion of the bottom wall. The molded food product includes ridges which correspond to the ridges in the bottom wall of the mold cavity. A lid is attached to the sheet to enclose and package the molded food product within the mold cavity.

Abstract: The invention relates to a multimode optical fibre having a refractive index profile, comprising a light-guiding core surrounded by one or more cladding layers. The present invention furthermore relates to an optical communication system comprising a transmitter, a receiver and a multimode optical fibre.

Abstract: A first hydraulic cylinder is associated with a boom. A first sensor detects a boom position based on a first linear position of a first movable member associated with the first hydraulic cylinder. An attachment is coupled to the boom. A second cylinder is associated with the attachment. A second sensor detects an attachment position based on a second linear position of a second movable member associated with the second hydraulic cylinder. A switch accepts a command to enter a ready position state from another position state. A controller controls the first hydraulic cylinder to attain a target boom position and for controlling the second cylinder to attain a target attachment position associated with the ready position state in response to the command.

Abstract: A first sensor detects a boom position of a boom based on a first linear position of a first movable member of a first hydraulic cylinder. A second sensor detects an attachment position of an attachment based on a second linear position of a second movable member of a second hydraulic cylinder. An accelerometer detects an acceleration or deceleration of the boom. A switch accepts a command to enter a ready position state from another position state. A controller controls the first hydraulic cylinder to attain a target boom position and for controlling the second cylinder to attain a target attachment position associated with the ready position state in response to the command in conformity with at least one of a desired boom motion curve and a desired attachment motion curve.

Abstract: A first hydraulic cylinder is associated with a boom. A first sensor detects a boom angle of a boom with respect to a support (or a vehicle). An attachment is coupled to one end of the boom. A second hydraulic cylinder is associated with the attachment. A second sensor detects an attachment position of attachment based on a second linear position of a second movable member of the second hydraulic cylinder. An accelerometer detects an acceleration or deceleration of the boom. A switch is arranged to accept a command to move to a preset position from another position. A controller is capable of controlling the first hydraulic cylinder to attain a target boom position and for controlling the second cylinder to attain a target attachment position associated with the preset position in response to the command in conformity with at least one of a desired boom motion curve and a desired attachment motion curve.