Patents by Inventor Mark Spyvee

Mark Spyvee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS
    Publication number: 20230126280
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Application
    Filed: December 5, 2022
    Publication date: April 27, 2023
    Inventors: Mark Spyvee, Pravin S. Shirude
  • Hydantoin containing deoxyuridine triphosphatase inhibitors
    Patent number: 11584723
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: February 21, 2023
    Assignee: CV6 Therapeutics (NI) Limited
    Inventors: Mark Spyvee, Pravin S. Shirude
  • HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS
    Publication number: 20220402879
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Application
    Filed: May 14, 2021
    Publication date: December 22, 2022
    Inventors: Mark Spyvee, Pravin S. Shirude
  • Nitrogen ring linked deoxyuridine triphosphatase inhibitors
    Patent number: 11518746
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: December 6, 2022
    Assignee: CV6 Therapeutics (NI) Limited
    Inventors: Mark Spyvee, Robert D. Ladner
  • Deoxyuridine triphosphatase inhibitors
    Patent number: 11479531
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: October 25, 2022
    Assignees: University of Southern California, CV6 Therapeutics (NI) Limited
    Inventors: Robert D. Ladner, Mark Spyvee, Pravin S. Shirude
  • IMPROVED INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME
    Publication number: 20220194932
    Abstract: Disclosed herein are inhibitors of the Notch transcriptional activation complex, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: Formula (I), wherein the substituents are as described.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 23, 2022
    Inventors: Anthony J. Capobianco, Mark Spyvee, Luisana Astudillo, Darren Orton
  • Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage
    Patent number: 11198677
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: December 14, 2021
    Assignees: University of Southern California, CV6 Therapeutics (NI) Limited
    Inventors: Robert D. Ladner, Mark Spyvee, Pravin S. Shirude
  • 6-membered uracil isosteres
    Patent number: 11174271
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: November 16, 2021
    Assignee: CV6 Therapeutics (NI) Limited
    Inventors: Mark Spyvee, Michael Lewis
  • Amino sulfonyl compounds
    Patent number: 11168059
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: November 9, 2021
    Assignee: CV6 Therapeutics (NI) Limited
    Inventor: Mark Spyvee
  • Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
    Patent number: 11124485
    Abstract: Provided herein are dUTPase inhibitors of Formula (I), compositions comprising such compounds and methods of using such compounds and compositions
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: September 21, 2021
    Assignee: CV6 Therapeutics (NI) Limited
    Inventors: Mark Spyvee, Pravin S. Shirude
  • Hydantoin containing deoxyuridine triphosphatase inhibitors
    Patent number: 11104649
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: August 31, 2021
    Assignee: CV6 Therapeutics (NI) Limited
    Inventors: Mark Spyvee, Pravin S. Shirude
  • Hydantoin containing deoxyuridine triphosphatase inhibitors
    Patent number: 11014924
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: May 25, 2021
    Assignee: CV6 Therapeutics (NI) Limited
    Inventors: Mark Spyvee, Robert D. Ladner
  • NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS
    Publication number: 20210061767
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Application
    Filed: November 6, 2020
    Publication date: March 4, 2021
    Inventors: Mark Spyvee, Robert D. Ladner
  • Hydantoin containing deoxyuridine triphosphatase inhibitors
    Patent number: 10858344
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: December 8, 2020
    Assignee: CV6 Therapeutics (NI) Limited
    Inventor: Mark Spyvee
  • Nitrogen ring linked deoxyuridine triphosphatase inhibitors
    Patent number: 10829457
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: November 10, 2020
    Assignee: CV6 THERAPEUTICS (NI) LIMITED
    Inventors: Mark Spyvee, Robert D. Ladner
  • DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CONTAINING AMINO SULFONYL LINKAGE
    Publication number: 20200325105
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Application
    Filed: February 24, 2020
    Publication date: October 15, 2020
    Inventors: Robert D. Ladner, Mark Spyvee, Pravin S. Shirude
  • DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CONTAINING CYCLOPROPANO LINKAGE
    Publication number: 20200283394
    Abstract: Provided herein are dUTPase inhibitors of Formula (I), compositions comprising such compounds and methods of using such compounds and compositions
    Type: Application
    Filed: January 27, 2020
    Publication date: September 10, 2020
    Inventors: Mark Spyvee, Pravin S. Shirude
  • DEOXYURIDINE TRIPHOSPHATASE INHIBITORS
    Publication number: 20200270207
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Application
    Filed: March 2, 2020
    Publication date: August 27, 2020
    Inventors: Robert D. Ladner, Mark Spyvee, Pravin S. Shirude
  • HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS
    Publication number: 20200255385
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Application
    Filed: May 4, 2020
    Publication date: August 13, 2020
    Inventors: Mark Spyvee, Pravin S. Shirude
  • Deoxyuridine triphosphatase inhibitors
    Patent number: 10577321
    Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: March 3, 2020
    Assignees: University of Southern California, CV6 Therapeutics (NI) Limited
    Inventors: Robert D. Ladner, Mark Spyvee, Pravin S. Shirude