Patents by Inventor Mark Spyvee

Mark Spyvee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hemiasterlin derivatives and uses thereof
    Patent number: 7064211
    Abstract: The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1–R7, X1, X2, R, Q, and n are as defined herein.
    Type: Grant
    Filed: September 22, 2003
    Date of Patent: June 20, 2006
    Assignee: Eisai Co., Ltd.
    Inventors: James J. Kowalczyk, Galina Kuznetsov, Shawn Schiller, Boris M. Seletsky, Mark Spyvee, Hu Yang
  • Hrmiasterlin derivatives and uses thereof
    Publication number: 20050239870
    Abstract: The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein.
    Type: Application
    Filed: March 21, 2003
    Publication date: October 27, 2005
    Applicant: EISAI CO., LTD.,
    Inventors: James Kowalczyk, Galina Kuznetsov, Shawn Schiller, Boris Seletsky, Mark Spyvee, Hu Yang
  • Deazapurines and uses thereof
    Publication number: 20050124649
    Abstract: The present invention provides compounds having formula (I), wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.
    Type: Application
    Filed: January 7, 2003
    Publication date: June 9, 2005
    Applicant: EISAI CO., LTD
    Inventors: Jane Daun, Heather Davis, Bruce DeAcosta, Fabian Gusovsky, Ieharu Hishinuma, Yimin Jiang, Toshihiko Kaneko, Kouichi Kikuchi, Seiichi Kobayashi, Andre Lescarbeau, Xiang-Yi Li, Kenzo Muramoto, Norihito Ohi, Marc Pesant, Boris Seletsky, Mark Spyvee, Lynda Tremblay, Ye Yao, Hiromitsu Yokohama, Yan (Janet) Zhao, Wanjun Zheng
  • Compounds and methods for treating Toll-like receptor 2-related diseases and conditions
    Publication number: 20050113345
    Abstract: The present invention relates to compounds and methods useful in the prevention or treatment of diseases or conditions associated with Toll-like receptor 2 activation.
    Type: Application
    Filed: October 25, 2004
    Publication date: May 26, 2005
    Inventors: Jesse Chow, Fabian Gusovksy, Lynn Hawkins, Mark Spyvee
  • Hemiasterlin derivatives and uses thereof
    Publication number: 20040229819
    Abstract: The present invention provides compounds having formula (I): 1
    Type: Application
    Filed: September 22, 2003
    Publication date: November 18, 2004
    Inventors: James J. Kowalczyk, Galina Kuznetsov, Shawn Schiller, Boris M. Seletsky, Mark Spyvee, Hu Yang
  • Macrocyclic compounds useful as pharmaceuticals
    Publication number: 20040224936
    Abstract: The present invention provides compositions comprising compounds having formula (I): 1
    Type: Application
    Filed: September 9, 2003
    Publication date: November 11, 2004
    Inventors: Kenichi Chiba, Hong Du, Yoshihito Eguchi, Masanori Fujita, Masaki Goto, Fabian Gusovsky, Jean-Christophe Harmange, Atsushi Inoue, Megumi Kawada, Takatoshi Kawai, Yoshiyuki Kawakami, Akifumi Kimura, Makoto Kotake, Yoshikazu Kuboi, Tomohiro Matsushima, Yoshiharu Mizui, Kenzo Muramoto, Hideki Sakurai, Yong-Chun Shen, Hiroshi Shirota, Mark Spyvee, Isao Tanaka, John (Yuan) Wang, Ray Wood, Satoshi Yamamoto, Naoki Yoneda