Patents by Inventor Martin Alexander

Martin Alexander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170035733
    Abstract: The present application relates to a fixed dose combination comprising lacosamide and levetiracetam, as well as to dosage regimens including such fixed dose combinations. The fixed dose combinations are suitable for the oral or parenteral treatment of various diseases, including in particular epilepsy and/or epileptic seizures.
    Type: Application
    Filed: November 28, 2014
    Publication date: February 9, 2017
    Applicant: UCB PHARMA GMBH
    Inventors: Benjamin THOORENS, Andrew FADDEN, René Pierre PINARD, Florent ROBIN, Martin Alexander SCHUBERT, Frank TENNIGKEIT, Serge CUYPERS
  • Patent number: 9561719
    Abstract: A method and apparatus for delivering power to a hybrid vehicle is disclosed. The apparatus includes an apparatus for delivering power to a hybrid vehicle, the hybrid vehicle including a powertrain having a power take-off coupling, the powertrain including an engine and a transmission. The apparatus includes an electric motor operable to generate a torque, the motor being coupled to transmit a starting torque through the power take-off of the powertrain for starting the engine.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: February 7, 2017
    Assignee: GE HYBRID TECHNOLOGIES, LLC
    Inventors: Jonathan Mong Ling Lo, Jacek Gromadzki, Nicolas Louis Bouchon, Martin Alexander Strange, Victor Woo
  • Patent number: 9550737
    Abstract: A series of benzimidazole derivatives, being potent modulators of human TNF? activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: January 24, 2017
    Assignee: UCB Biopharma SPRL
    Inventors: Daniel Christopher Brookings, Mark Daniel Calmiano, Ellen Olivia Gallimore, Helen Tracey Horsley, Martin Clive Hutchings, James Andrew Johnson, Boris Kroeplien, Fabien Claude Lecomte, Martin Alexander Lowe, Timothy John Norman, John Robert Porter, Joanna Rachel Quincey, James Thomas Reuberson, Matthew Duncan Selby, Michael Alan Shaw, Zhaoning Zhu, Anne Marie Foley
  • Patent number: 9546233
    Abstract: A metal complex of the formula (1) CyAMX(L)n??(1) wherein Cy is a cyclopentadienyl-type ligand, M is a metal of group 4; A is an amidine-containing ligand moiety, represented by formula 2: wherein the amidine-containing ligand is covalently bonded to the metal M via the imine nitrogen atom, and Sub1 is a substituent comprising a group 14 atom through which Sub1 is bonded to the imine carbon atom and Sub2 is a substituent comprising a heteroatom of group 15, through which Sub2 is bonded to the imine carbon atom; X is an allyl borate ligand derived from a conjugated diene ligand, D, and a borane, B and L is a neutral Lewis basic ligand wherein the number of said metal ligands “n” is in the range of 1 to the amount that specifies the 18-electron rule.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: January 17, 2017
    Assignee: ARLANXEO NETHERLANDS B.V.
    Inventors: Richard Thomas William Scott, Martin Alexander Zuideveld, Philip Mountford
  • Publication number: 20160358266
    Abstract: The enterprise database system provides methods, data, and user interfaces for performing reassessments and creating financial and accounting disclosure reports. Data fields for entities are monitored for changes that are evident at the end of reporting periods and may trigger the need to reassess the categorization of the entity. The system receives a request to perform a reassessment based on changes to particular data fields during the reporting period. The system retrieves entities that require reassessment based on the trigger events applicable to the entities. A reassessment is performed for each of the entities having a trigger event and the reassessment is stored in a historical database. Based on the reassessment, the system generates prompts to re-categorize the reassessed entity. Following the reassessment and categorization, the system can generate a disclosure report that presents information about the newly categorized entity.
    Type: Application
    Filed: January 6, 2016
    Publication date: December 8, 2016
    Inventors: Nicholas Peter Dovas, Supattra Thummukgool, Venkatesan Ragunathan, Martin Alexander Staheli
  • Publication number: 20160355615
    Abstract: A catalyst system including a procatalyst, a co-catalyst and an external electron donor of Formula I?: Si(L)n(OR11)4-n-m(R12)m??Formula I? wherein, Si has a valency 4+; O has a valency 2? and O is bonded to Si via a silicon-oxygen bond; n is 1-4; m is 0-3; n+m?4; each R11 and R12 group is independently an alkyl or aromatic substituted or unsubstituted hydrocarbyl; each L group is independently of Formula II: wherein, L is bonded to the silicon atom via the nitrogen-silicon bond; L has a single substituent on the nitrogen atom, where this single substituent is an imine carbon atom; and X and Y are independently a hydrogen atom; a heteroatom of Groups 13-17; an alkyl, optionally containing a heteroatom of Groups 13-17 or an aromatic substituted and unsubstituted hydrocarbyl, optionally containing a heteroatom of Groups 13-17.
    Type: Application
    Filed: December 19, 2014
    Publication date: December 8, 2016
    Inventors: Martin Alexander Zuideveld, Erik Zuidema
  • Publication number: 20160340293
    Abstract: A catalyst composition including the compound of Formula I as an internal electron donor, wherein: R1, R2, R3, R4, R5 and R6 are independently selected from a group consisting of hydrogen, straight, branched and cyclic alkyl and aromatic substituted and unsubstituted hydrocarbyl having 1 to 20 carbon atoms; R7 is selected from a group consisting of straight, branched and cyclic alkyl and aromatic substituted and unsubstituted hydrocarbyl having 1 to 20 carbon atoms; and R8 is selected from a group consisting of aromatic substituted and unsubstituted hydrocarbyl having 6 to 20 carbon atoms. Also disclosed is a process for preparing said polymerization catalyst composition; a polymerization catalyst system comprising said catalyst composition, a co-catalyst and optionally an external electron donor; a polyolefin obtainable by the process; and use of the compound of Formula I as in internal electron donor in catalysts for polymerization of olefins.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 24, 2016
    Inventors: Mansour I. TAFTAF, Jaiprakash Brijlal SAINANI, Vladimir Aleksandrovich ZAKHAROV, Gennadii Dimitrievich BUKATOV, Vimalkumar Mahendrabhai PATEL, Sergei Andreevich SERGEEV, Martin Alexander ZUIDEVELD, Aurora Alexandra BATINAS-GEURTS, Nourdin GHALIT
  • Publication number: 20160333121
    Abstract: The present invention relates to a process for the preparation of a catalyst system suitable for olefin polymerization wherein the external electron donor is n-propyltriethoxysilane, and a catalyst system obtained or obtainable by said process. The invention also relates to a process for preparing a polyolefin using said catalyst system. The invention further relates to a polyolefin, in particular polyprolyene, obtainable by such a process, and shaped articles manufactured from such a polymer. The polymers produced using the catalyst system exhibit low volatiles and therefore have a reduced environmental and health impact.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 17, 2016
    Inventors: Aurora Alexandra Batinas-Geurts, Martin Alexander Zuideveld
  • Publication number: 20160326280
    Abstract: The invention relates to a process for preparing a catalyst system suitable for olefin polymerization. The present invention further relates to a catalyst system obtainable by such process. In addition, the invention relates to a polyolefm. The invention also relates to ashaped article. The catalyst system comprises a procatalyst, a co-catalyst and optionally at least one external electron donor.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 10, 2016
    Inventors: Aurora Alexandra Batinas-Geurts, Martin Alexander Zuideveld, Bobby Johannes Henricus Hubertus Smeets
  • Publication number: 20160311946
    Abstract: The invention relates to a process for the preparation of a procatalyst suitable for preparing a catalyst composition for olefin polymerization. The invention also relates to a procatalyst obtained or obtainable by the process. The invention further relates to the use of a benzamide as an activator in the preparation of a Ziegler-Natta procatalyst. The invention also relates to a process for the preparation of polyolefins. The invention also relates to a polyolefin. The invention further relates to a shaped article.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 27, 2016
    Inventors: Martin Alexander ZUIDEVELD, Aurora Alexandra BATINAS-GEURTS, Gennadii Dimitrievich BUKATOV, Sergei Andreevich SERGEEV, Vladimir Aleksandrovich ZAKHAROV
  • Publication number: 20160311947
    Abstract: A process for the preparation of a procatalyst suitable for preparing a catalyst composition for olefin polymerization, the procatalyst obtained or obtainable by the process; and a catalyst composition for olefin polymerization comprising the procatalyst. In particular a benzamide can be used as an activator in the preparation of a supported Ziegler-Natta type procatalyst useful for a process for the preparation of polyolefins. The Polyolefins and polypropylene homopolymers are also disclosed.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 27, 2016
    Inventors: Martin Alexander Zuideveld, Aurora Alexandra Batinas-Geurts, Gennadii Dimitrievich Bukatov, Sergei Andreevich Sergeev, Vladimir Aleksandrovich Zakharov
  • Publication number: 20160311950
    Abstract: A process for the preparation of a catalyst system for olefin polymerization, including: A) providing said procatalyst obtainable via a process comprising: i) contacting a compound R4zMgX42-z with an alkoxy- or aryloxy-containing silane compound to give a first intermediate reaction product, ii) optionally contacting the solid product obtained in step i) with at least one activating compound selected from an activating electron donor or metal alkoxide compound; iii) contacting the first or second intermediate reaction product, with a halogen-containing Ti-compound and optionally an internal electron donor to obtain the procatalyst; and B) contacting the procatalyst with a co-catalyst and at least diethylaminotriethoxysilane as the external donor.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 27, 2016
    Applicants: Saudi Basic Industries Corporation, Sabic Global Technologie B.V.
    Inventors: Aurora Alexandra Batinas-Geurts, Martin Alexander Zuideveld, Raymond Gerlofsma, Henrica Norberta Alberta Maria Steenbakkers-Menting, Peter Degenhart
  • Publication number: 20160304514
    Abstract: A series of substituted 4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
    Type: Application
    Filed: December 8, 2014
    Publication date: October 20, 2016
    Inventors: Victoria Elizabeth Jackson, Boris Kroeplien, Martin Alexander Lowe, John Robert Porter
  • Publication number: 20160297818
    Abstract: A series of substituted purine derivatives, being potent modulators of human TNF? activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
    Type: Application
    Filed: December 8, 2014
    Publication date: October 13, 2016
    Inventors: Victoria Elizabeth Jackson, Boris Kroeplien, Martin Alexander Lowe, John Robert Porter
  • Publication number: 20160199725
    Abstract: A game in which the moves players can make simulate both the symmetric and antisymmetric couplings of muscle pairs that accompany co-ordinated movement of the two sides of the human body, and in which each player's move comprises two components, one beneficial to the player and the other beneficial to the player(s) opponents (herein called chiralkines); a kit for playing the game; an electronic gaming device for use in playing the game; left- and right handed money and left- and right-handed property rights for use in a game or commerce; and apparatuses adapted for use with these.
    Type: Application
    Filed: March 24, 2016
    Publication date: July 14, 2016
    Inventor: Martin Alexander Hay
  • Publication number: 20160176998
    Abstract: The present invention relates to a catalyst system comprising a procatalyst, a co-catalyst and an external electron donor, wherein the external electron donor comprises a compound having the structure according to Formula I: Si(L)n(OR11)4-n (Formula I), wherein, Si is a silicon atom with valency 4+; O is an oxygen atom with valency 2? and O is bonded to Si via the silicon-oxygen bond; n is 1, 2, 3 or 4; R11 is a selected from the group consisting of linear, branched and cyclic alkyl having at most 20 carbon atoms and aromatic substituted and unsubstituted hydrocarbyl having 6 to 20 carbon atoms; L is a group represented by (Formula II), wherein, L is bonded to the silicon atom via the nitrogen-silicon bond; L has a single substituent on the nitrogen atom, where this single substituent is an imine carbon atom; and X and Y are independently selected from the group consisting of a hydrogen atom; a heteroatom selected from group 13, 14, 15, 16 or 17 of the IUPAC Periodic Table of the Elements; a linear, branched
    Type: Application
    Filed: August 11, 2014
    Publication date: June 23, 2016
    Applicant: SAUDI BASIC INDUSTRIES CORPORATION
    Inventors: Martin Alexander Zuideveld, Jaiprakash Brijlal Sainani, Vimalkumar Mahendrabhai Patel
  • Publication number: 20160122370
    Abstract: The present invention relates to a new bimetallic complex of the formula (1) wherein: M is a group 4-6 metal R1 means is a substituent comprising a heteroatom of group 15, through which R1 is bonded to the imine carbon atom; R2-R6 are the same or different and each represents a hydrogen atom, an optionally substituted C1-10 alkyl group, an optionally substituted C1-10 alkoxy group, an optionally substituted C6-20 aryl group, an optionally substituted C6-20 aryloxy group, an optionally substituted C7-20 aralkyl group, an optionally substituted C7-20 aralkyloxy group, a silyl group substituted with optionally substituted C1-20 hydrocarbon group(s), a C1-20 hydrocarbon-substituted amino group or the adjacent R2-R6 may be linked to each other to form a ring; R7-R10 are the same or different and each represents a hydrogen atom, a halogen atom, an optionally substituted C1-10 alkyl group, an optionally substituted C1-10 alkoxy group, an optionally substituted C6-20 aryl group, an optionally substituted C6-20 arylox
    Type: Application
    Filed: June 18, 2014
    Publication date: May 5, 2016
    Inventors: Alexandra BERTHOUD, Victor QUIROGA NORAMBUENA, Gerard VAN DOREMAELE, Martin Alexander ZUIDEVELD, Henricus Johannes ARTS, Richard Thomas William SCOTT
  • Publication number: 20160122455
    Abstract: The present invention relates to a new metal complex of the formula (1) wherein: M is a group 4-6 metal R1 means is a substituent comprising a heteroatom of group 15, through which R1 is bonded to the imine carbon atom; R2-R5 are the same or different and each represents a hydrogen atom, an optionally substituted C1-10 alkyl group, an optionally substituted C1-10 alkoxy group, an optionally substituted C6-20 aryl group, an optionally substituted C6-20 aryloxy group, an optionally substituted C7-20 aralkyl group, an optionally substituted C7-20 aralkyloxy group, a silyl group substituted with optionally substituted C1-20 hydrocarbon group(s), a C1-20 hydrocarbon-substituted amino group or the adjacent R2-R5 may be linked to each other to form a ring; R6-R9 are the same or different and each represents a hydrogen atom, a halogen atom, an optionally substituted C1-10 alkyl group, an optionally substituted C1-10 alkoxy group, an optionally substituted C6-20 aryl group, an optionally substituted C6-20 arylox
    Type: Application
    Filed: May 7, 2014
    Publication date: May 5, 2016
    Applicant: LANXESS Elastomers B.V.
    Inventors: Alexandra BERTHOUD, Victor QUIROGA NORAMBUENA, Gerhard VAN DOREMAELE, Martin Alexander ZUIDEVELD, Philip MOUNTFORD, Richard Thomas William SCOTT
  • Publication number: 20160115265
    Abstract: A metal complex of the formula (1) CyAMX(L)n??(1) wherein Cy is a cyclopentadienyl-type ligand, M is a metal of group 4; A is an amidine-containing ligand moiety, represented by formula 2: wherein the amidine-containing ligand is covalently bonded to the metal M via the imine nitrogen atom, and Sub1 is a substituent comprising a group 14 atom through which Sub1 is bonded to the imine carbon atom and Sub2 is a substituent comprising a heteroatom of group 15, through which Sub2 is bonded to the imine carbon atom; X is an allyl borate ligand derived from a conjugated diene ligand, D, and a borane, B and L is a neutral Lewis basic ligand wherein the number of said metal ligands “n” is in the range of 1 to the amount that specifies the 18-electron rule.
    Type: Application
    Filed: May 7, 2014
    Publication date: April 28, 2016
    Inventors: Richard Thomas William SCOTT, Martin Alexander ZUIDEVELD, Philip MOUNTFORD
  • Patent number: 9315594
    Abstract: The invention relates to a catalyst system for the polymerization of olefins comprising a metal complex of formula CyLMD and an activating cocatalyst, wherein M is titanium, Cy is a cyclopentadienyl-type ligand, D is a diene, L is a guanidinate-containing ligand of the formula (I) wherein each A is independently selected from nitrogen or phosphorous and R, R1, R2 and R3 are independently selected from the group consisting of hydrogen, hydrocarbyl, silyl and germyl residues, substituted or not with one or more halogen, amido, phosphido, alkoxy, or aryloxy radicals, and Cy is a mono- or polysubstituted cyclopentadienyl-type ligand, wherein the one or more substituents of Cy are selected from the group consisting of halogen, hydrocarbyl, silyl and germyl residues, optionally substituted with one or more halogen, amido, phosphido, alkoxy, or aryloxy residues.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: April 19, 2016
    Assignee: LANXESS Elastomers B.V.
    Inventors: Van Gerardus Henricus Josephus Doremaele, Martin Alexander Zuideveld, Victor Fidel Quiroga Norambuena, Philip Mountford, Richard Scott