Patents by Inventor Martin Huber

Martin Huber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhalation device for use in aerosol therapy
    Patent number: 8910625
    Abstract: An inhalation device having a base unit, a mouthpiece, and an aerosol head is provided. The base unit has an air inlet, an air outlet opening, a groove for receiving the mouthpiece, and key lock member(s). The mouthpiece has two segments: a first segment which is insertable into the groove of the base unit and has an air inlet opening and a lateral opening for receiving an aerosol generator and a second segment with an aerosol outlet. The aerosol head has an aerosol generator, a liquid reservoir, and key lock member(s) complementary to those of the base unit. The base unit, mouthpiece and aerosol head are connectible with one another such that when engaging the members of the key lock with the complementary members, the aerosol generator is inserted into the lateral opening of the mouthpiece.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: December 16, 2014
    Assignee: Vectura GmbH
    Inventors: Bernhard Mullinger, Tobias Kolb, Martin Huber, Tobias Hoffmann
  • INHALATION DEVICE WITH FEEDBACK SYSTEM
    Publication number: 20140352690
    Abstract: The invention provides an inhalation device for enabling a user to inhale at a desired inspiratory flow rate and/or pressure, comprising a feedback system configured to indicate to a user by means of a signal during an inhalation manoeuvre whether an inhalation parameter, such as the inspiratory flow rate, is within a predefined target range. The signal may be an optical or a non-optical signal, such as a light signal, an acoustic signal, or a tactile signal.
    Type: Application
    Filed: December 27, 2012
    Publication date: December 4, 2014
    Inventors: Tobias Kolb, Tobias Hoffman, Sebastian Schwendner, Martin Huber, Bernhard Muellinger
  • HYBRID NANOPORE DEVICE WITH OPTICAL DETECTION AND METHODS OF USING SAME
    Publication number: 20140335513
    Abstract: The invention is directed to a device comprising a protein nanopore immobilized in a lipid layer within an aperture of a solid phase substrate, which provides a stable platform for using first and second members of one or more FRET pairs to generate optical signals as a labeled analyte translocates through the bore of the protein nanopore. In another aspect, the invention is directed to the use of the device to determine the nucleotide sequence of a polynucleotide analyte.
    Type: Application
    Filed: October 28, 2012
    Publication date: November 13, 2014
    Applicant: QUANTAPORE, INC.
    Inventors: Martin Huber, Bason E. Clancy
  • VEHICLE ELECTRICAL SYSTEM COMPONENT FOR A DATA TRANSMISSION SYSTEM IN A MOTOR VEHICLE
    Publication number: 20140332250
    Abstract: A vehicle electrical system component for a data transmission system in a motor vehicle, in particular for an Ethernet transmission system, having a cable with wires and a plug having wire connection contacts for contacting the wires, wherein the wires have an electrical insulation, wherein a common shielding is arranged around the wires which is enclosed by a common cable sheath, wherein the cable has at least three wires and an electrically conductive drain wire, wherein the drain wire contacts the shielding at least in sections and is contacted to a wire connection contact of the plug.
    Type: Application
    Filed: September 13, 2012
    Publication date: November 13, 2014
    Applicants: MD-ELEKTRONIC GMBH, VOLKSWAGEN AG
    Inventors: Lorena Diaz Ortega, Volker Wehrmeyer, Norbert Friese, Martin Huber
  • Method and device for operating a vehicle, in particular a motor vehicle or utility vehicle
    Patent number: 8880313
    Abstract: A method operates a vehicle having an acquisition device for acquiring defined route section data of an upcoming route section to be passed through via the vehicle, in particular a utility vehicle. Accordingly, the route section data, which are acquired by the acquisition device are evaluated in an evaluation device with respect to the wear reduction potential of a vehicle-side wearing part for the upcoming route section to be passed through such that, to reduce and/or optimize the wear of the wearing part. An actuating parameter, in particular an actuating time and/or an actuating duration, is predetermined for the wearing part in the upcoming route section to be passed through. An auxiliary device which supports the wearing part in its action is activated in the upcoming route section to be passed through in accordance with at least one predefined auxiliary device parameter.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: November 4, 2014
    Assignee: MAN Truck & Bus AG
    Inventors: Karlheinz Dörner, Andreas Zimmermann, Daniel Heyes, Martin Huber, Peter Drimml, Britta Michel
  • BATTERY HOUSING AND METHOD FOR INSTALLING A BATTERY
    Publication number: 20140322582
    Abstract: A battery housing (10) for receiving a battery and a method of installing a battery, where the battery housing has four plate-shaped side panels (11a-11d) and two cover plates (12a, 12b), which may be connected with one another to form a box-shaped housing, whereby at least two opposite side panels (11a, 11c) each have at least one elongated recess (13a, 13c) inside, into which a functional battery plate (30) may be inserted, and the side panels (11a-11d) are connected with one another, such that they hold the whole battery without installed cover plates (12a, 12b).
    Type: Application
    Filed: April 24, 2014
    Publication date: October 30, 2014
    Applicant: Lisa Dräxlmaier GmbH
    Inventors: Karsten Rüter, Guido Hofer, Stefan Deser, Martin Huber, Matthias Stein, Michael Koller, Andreas Kraft
  • CELL BLOCK WITH CELL FIXATION FOR A BATTERY AND METHOD OF ASSEMBLING A CELL BLOCK
    Publication number: 20140322581
    Abstract: A cell block (60) for a battery (1) and a method for assembling a cell block (60) having one or more battery cells (70), said cell block (60) having a box-shaped housing (61), which is open on one side, into which, the battery cells (70) are fitted through the open side, and a cell fixation (80) is pushed through the open side into the housing (61), such that the battery cells (70) are fixed in the housing (61) and the housing (61) is at least partially closed, whereby the cell fixation (80) has one or more bond openings (82) through which, the battery cells (70) may be accessed after the cell fixation (80) has been pushed in, and a projecting collar (81) is provided at least partially around a bond opening (82) on the side of the cell fixation (80) facing away from the battery cells (70), whereby the collar (81) may be brought into contact with an end plate (105).
    Type: Application
    Filed: April 24, 2014
    Publication date: October 30, 2014
    Applicant: Lisa Dräxlmaier GmbH
    Inventors: Karsten Rüter, Martin Huber, Guido Hofer
  • ULTRAFAST SEQUENCING OF BIOLOGICAL POLYMERS USING A LABELED NANOPORE
    Publication number: 20140255935
    Abstract: Methods and systems for sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. One or more donor labels, which are attached to a pore or nanopore, may be illuminated or otherwise excited. A polymer having a monomer labeled with one or more acceptor labels, may be translocated through the pore. Either before, after or while the labeled monomer of the polymer passes through, exits or enters the pore, energy may be transferred from the excited donor label to the acceptor label of the monomer. As a result of the energy transfer, the acceptor label emits energy, and the emitted energy is detected in order to identify the labeled monomer of the translocated polymer and to thereby sequence the polymer.
    Type: Application
    Filed: May 22, 2014
    Publication date: September 11, 2014
    Applicant: QUANTAPORE, INC.
    Inventor: Martin HUBER
  • Method and system for medical decision support using organ models and learning based discriminative distance functions
    Patent number: 8812431
    Abstract: A method and system for providing medical decision support based on virtual organ models and learning based discriminative distance functions is disclosed. A patient-specific virtual organ model is generated from medical image data of a patient. One or more similar organ models to the patient-specific organ model are retrieved from a plurality of previously stored virtual organ models using a learned discriminative distance function. The patient-specific valve model can be classified into a first class or a second class based on the previously stored organ models determined to be similar to the patient-specific organ model.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: August 19, 2014
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ingmar Voigt, Dime Vitanovski, Razvan Ioan Ionasec, Alexey Tsymbal, Bogdan Georgescu, Shaohua Kevin Zhou, Martin Huber, Dorin Comaniciu
  • Ultrafast sequencing of biological polymers using a labeled nanopore
    Patent number: 8771491
    Abstract: Methods and systems for sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. One or more donor labels, which are attached to a pore or nanopore, may be illuminated or otherwise excited. A polymer having a monomer labeled with one or more acceptor labels, may be translocated through the pore. Either before, after or while the labeled monomer of the polymer passes through, exits or enters the pore, energy may be transferred from the excited donor label to the acceptor label of the monomer. As a result of the energy transfer, the acceptor label emits energy, and the emitted energy is detected in order to identify the labeled monomer of the translocated polymer and to thereby sequence the polymer.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: July 8, 2014
    Assignee: Quantapore, Inc.
    Inventor: Martin Huber
  • Nalmefene hydrochloride dihydrate
    Patent number: 8754217
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dihydrate.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 17, 2014
    Assignee: H. Lundbeck A/S
    Inventors: Heidi Lopez de Diego, Carla De Faveri, Florian Anton Martin Huber
  • METHOD FOR THE MANUFACTURING OF NALTREXONE
    Publication number: 20140155608
    Abstract: The present invention relates to a new process for producing naltrexone [17-(cyclopropylmethyl)-4,5?-epoxy-3,14-dihydroxy-morphinan-6-one] from noroxymorphone [4,5-?-epoxy-3,14-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.
    Type: Application
    Filed: May 2, 2013
    Publication date: June 5, 2014
    Inventors: Carla De Faveri, Mariano Stivanello, Florian Anton Martin Huber
  • INHALATION DEVICE FOR USE IN AEROSOL THERAPY
    Publication number: 20140116426
    Abstract: The invention provides an inhalation device comprising a base unit, a mouthpiece, and an aerosol head. The base unit comprises an air inlet, an air outlet opening, a groove for receiving the mouthpiece, and key lock member(s). The mouthpiece comprises a first segment, comprising an air inlet opening and a lateral opening for receiving an aerosol generator, the first segment being insertable into the groove of the base unit, and a second segment comprising an aerosol outlet. The aerosol head comprises an aerosol generator, a liquid reservoir, and key lock member(s) complementary to the key lock member(s) of the base unit. The base unit, mouthpiece and aerosol head are connectable with one another such that when engaging the members of the key lock with the complementary members, the aerosol generator is inserted into the lateral opening of the mouthpiece.
    Type: Application
    Filed: October 25, 2013
    Publication date: May 1, 2014
    Applicant: ACTIVAERO GMBH
    Inventors: Bernhard Mullinger, Tobias Kolb, Martin Huber
  • Device for flow rate limitation at low differential pressures
    Patent number: 8684002
    Abstract: A device for the flow rate limitation at low differential pressures, in particular for the limitation of the inhalation volume flow during the inhalation of therapeutic aerosols, comprising a housing with at least an inlet opening, at least an outlet opening and a flow channel arranged therebetween, wherein the flow channel is restricted by a flexible wall extending along the flow channel, characterized in that the flexible wall has a control area of less than 100 mm2.
    Type: Grant
    Filed: August 3, 2010
    Date of Patent: April 1, 2014
    Assignee: Activaero GmbH
    Inventors: Martin Huber, Tobias Kolb, Bernhard Müllinger
  • APPARATUS AND METHODS FOR PERFORMING OPTICAL NANOPORE DETECTION OR SEQUENCING
    Publication number: 20140087474
    Abstract: Methods and systems for detecting or sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. Optical sequencing of a molecule may be performed utilizing an optical or photon detector operated in time delayed integration mode. In certain variations, the translocation rate of molecules through a, pore, nanopore or channel may be controlled or reduced by increasing the diameter of the molecules to allow for molecule detection or sequencing by optical or electrical detection. In certain variations, a plurality or an array of, pores, nanopores, or channels may be utilized to optically detect a plurality of molecules.
    Type: Application
    Filed: September 4, 2013
    Publication date: March 27, 2014
    Applicant: Quantapore, Inc.
    Inventor: Martin HUBER
  • PROCESS INTERMEDIATES AND METHODS FOR THE PREPARATION OF PROCESS INTERMEDIATES FOR THE SYNTHESIS OF ARGATROBAN MONOHYDRATE
    Publication number: 20140088310
    Abstract: Methods are provided for the synthesis of key intermediates for the synthesis of Argatroban monohydrate, ethyl (2R,4R)-1-[(2S)-2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methylpiperidine-2-carboxylate compounded with HCl. Such intermediates are also provided.
    Type: Application
    Filed: March 26, 2012
    Publication date: March 27, 2014
    Applicant: LUNDBECK PHARMACEUTICALS ITALY S.P.A.
    Inventors: Mariano Stivanello, Florian Anton Martin Huber, Antonio Ricci
  • Adapter element for serial data transfer in a vehicle
    Patent number: 8628354
    Abstract: An adapter element for serial data transfer in a vehicle, the adapter element including a first housing part, which is designed electrically conductively and is connectable to a shield and a second housing part, which is designed electrically conductively and includes a contact element. The first housing part and the second housing part are disposed such that the second housing part is enclosed by the first housing part in a first region that extends along a longitudinal axis of the adapter element. The contact element is in electrical contact in the first region with the first housing part, and the contact element produces the electrical contact at least in part by the adapter element being configured such that accessibility to the contact element from a position exterior to the adapter element in a direction that is orthogonal to the longitudinal axis is ensured.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: January 14, 2014
    Assignee: MD Elektronik GmbH
    Inventors: Martin Huber, Udo Schuster
  • NALMEFENE HYDROCHLORIDE DIHYDRATE
    Publication number: 20130338365
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dehydrate.
    Type: Application
    Filed: June 25, 2013
    Publication date: December 19, 2013
    Inventors: Heidi Lopez de DIEGO, Carla de FAVERI, Florian Anton Martin HUBER
  • Electrical cable and method and device for the manufacture thereof
    Patent number: 8609989
    Abstract: An electrical cable including an inner conductor arrangement having a longitudinally extended conductor. The electrical cable further including an outer sheath that surrounds the inner conductor arrangement annularly in cross-section, and an electrical shield that extends between the inner conductor arrangement and the outer sheath, wherein a portion of the electrical shield is turned inside out in such a way that it is spaced apart from a main area of the electrical shield. The portion defines an inside-out portion and extends between the inner conductor arrangement and the outer sheath transversely to a direction in which the electrical cable extends. In addition, an exterior region of the inside-out portion of the electrical shield is incorporated in at least some portions into the sheath of the electrical cable.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: December 17, 2013
    Assignee: MD Elektronik GmbH
    Inventor: Martin Huber
  • Method for the manufacturing of naltrexone
    Patent number: 8580963
    Abstract: The present invention relates to an improved process for producing naltrexone[17-(cyclopropylmethyl)-4,5?-epoxy-3,14-dihydroxy-morphinan-6-one] from noroxymorphone[4,5-?-epoxy-3,14-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: November 12, 2013
    Assignee: H. Lundbeck A/S
    Inventors: Carla De Faveri, Florian Anton Martin Huber, Mariano Stivanello