Abstract: An electrical connector for a multi-wire electrical cable includes two cable-side electrical contact elements, including associated terminals to each of which is to be connected a wire of the electrical cable, as well as two output-side electrical contact elements, from each of which projects an electrical connector element by which an electrical connection can be established to a mating connector. A carrier body is disposed between the cable-side contact elements and the output-side contact elements. The carrier body forms a support region which extends from a first connecting section to a second connecting section and with which both the cable-side and the output-side contact elements are in connection. At each of the two connecting sections, a respective supporting section of the carrier body extends from the support region in such a way that the support region and the two supporting sections form a ring-shaped circumferential structure.

Abstract: An electrical connector includes at least two electrical connector elements extending side by side along a longitudinal direction, each of the electrical connector elements being connectable to a respective wire of an associated electrical cable. An electrical device is in electrical contact with the respective electrical connector elements. A flexible carrier surrounds the electrical connector elements annularly in cross section, and the electrical device is mounted on an inner side of the flexible carrier which faces the connector elements.

Abstract: The invention relates to an arrangement of a machine tool (10) and a workpiece holder (111) connected to a workpiece (14), wherein the workpiece holder (111) comprises at least one surface (111a) pointing radially towards the outside, in particular a substantially planar surface, which is configured for contact with a clamping element (109) of a multi-axis workpiece arm (11) which clamping element (109) is disposed in the radial direction between the workpiece holder (111) and a chuck (120), wherein the clamping element (109) is displaceable relative to the chuck (120) for clamping and releasing the workpiece holder (111), wherein the clamping element (109) is configured to vary a clamping force (F) exerted on the workpiece holder (111) when it is displaced relative to the chuck (120).

Abstract: The invention relates to a system for a method for controlling a machine tool with at least one replaceable tool and a workpiece, especially a mill blank, and for a method for machining the workpiece, which machine tool comprises a robot arm movable along at least 2, especially at least 3 space axes in an area of motion, which carries and moves at least one workpiece, eventually via a workpiece holder, with a control unit for controlling the machine tool. The machine tool (52) includes a sensor (46), especially a space-fixed optical sensor located thereon or associated thereto, and the detection range (42) of which overlaps the area of motion at least partially for detection of a code on the machine tool.

Abstract: An electrical connector for a multi-wire electrical cable includes at least two cable-side electrical contact elements including associated terminals to each of which is connected a wire of the electrical cable, and at least two output-side electrical contact elements, from each of which projects an electrical connector element by which a mating connector is electrically connectable. A tubular outer conductor extends along a longitudinal direction from a cable-side end to an output-side end and encloses the cable-side and output-side contact elements. At least one stranded drain wire of the electrical cable contacts a shield of the electrical cable and is guided to the electrical connector separately from the wires of the electrical cable. The outer conductor has at least one second slot extending along the longitudinal direction of the outer conductor, and the drain wire is received in the second slot in the outer conductor.

Abstract: The invention is directed to articles of manufacture for constraining movement of molecules, such as polynucleotides, and methods of using the same. In some embodiments, article of manufacture of the invention comprise (i) a solid state membrane having at least one aperture extending therethrough from a first side to a second side; (ii) an annular DNA sheet having a central opening disposed on the first side of the solid state membrane such that the annular DNA sheet spans an aperture and the central opening is aligned with the aperture to provide fluid communication between the first side and the second side of the solid state membrane through the aperture; and (iii) a protein nanopore immobilized in the central opening of the annular DNA sheet spanning the aperture. Uses of such articles of manufacture include determining sequences of nucleic acids.

Abstract: Methods are provided for the synthesis of key intermediates for the synthesis of Argatroban monohydrate, ethyl (2R,4R)-1-[(2S)-2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methylpiperidine-2-carboxylate compounded with HCl. Such intermediates are also provided.

Abstract: The invention relates to a double-layer component (1) having a first layer (2) and a second layer (3), wherein the layers (2, 3) are connected to one another, wherein the two layers (2, 3) have different coefficients of thermal expansion, wherein the first layer (2) comprises a first plastic and the second layer (3) comprises a second plastic or carbon fibres, wherein the double-layer component (1) is reversibly deformable under the influence of heat. The double-layer component (1) is improved in that the double-layer component (1) can be inserted into a heat engine (4), wherein the thickness of the double-layer component (1) is at least 0.1 mm, wherein the thickness of the double-layer component (1) is 5 cm or less than 5 cm.

Abstract: An electrical connector for a multi-wire electrical cable includes at least two cable-side electrical contact elements including associated electrical terminals to each of which is to be connected a wire of the electrical cable. At least two output-side electrical contact elements, from each of which projects an electrical connector element by which an electrical connection can be established to a mating connector. An electrically conductive carrier body is disposed between the cable-side contact elements and the output-side contact elements. The electrically conductive carrier body carries an electrical device by which the cable-side contact elements and the output-side contact elements are electrically connected to each other. The electrical device is supported by the carrier body without any of the cable-side contact elements or the output-side contact elements being in electrical contact with the carrier body through the electrical device.

Abstract: A dental milling machine is provided with a tool which is guided in a chuck. A workpiece arm is mounted opposite the tool to be able to be moved at least in the direction of the spindle axis. With a control device it can be moved in relation to the workpiece, especially by means of a drive motor of the workpiece arm. The workpiece arm has an abutment element, whereby the control device moves the tool and the abutment element towards each other until they abut each other. The control device can be used to detect abutment of the abutment element with respect to the tool, in particular with respect to its tip, in particular by decelerating the (relative) movement of the tool and the abutment element towards each another, upon contact of the tool and the abutment element. This position may be signaled as a reference position and, especially may be stored.

Abstract: This invention relates to a novel chemical process for the synthesis of N?-benzyl-5-methylisoxazole-3-carbohydrazide (Isocarboxazid) which comprises reacting 5-methyl-3-isoxazole carboxylic acid ester with benzylhydrazine or a salt thereof in an aprotic organic solvent and in the presence of an organic base.

Abstract: An electrical connector for a multi-wire electrical cable has two or more cable-side electrical contact elements including associated electrical terminals to each of which is to be connected a wire of the electrical cable, and has two or more output-side electrical contact elements, from each of which projects an electrical connector element via which an electrical connection is establishable to a mating connector. An inductive electrical device is disposed between the cable-side and the output-side electrical contact elements. The inductive electrical device is integrally formed with the cable-side and/or the output-side electrical contact elements. The cable-side and the output-side electrical contact elements are electrically connected to each other via the inductive electrical device.

Abstract: An electrical cable includes at least two wires extending side by side along a longitudinal cable direction. The wires are electrically insulated from each other by an insulation. An electrical device is in electrical contact with the respective wires. A flexible carrier surrounds the wires annularly in cross section, and the electrical device is mounted on an inner side of the flexible carrier which faces the wires.

Abstract: An electrical connector includes at least two electrical connector elements extending side by side along a longitudinal direction, each of the electrical connector elements being connectable to a respective wire of an associated electrical cable. An electrical device is in electrical contact with the respective electrical connector elements. A flexible carrier surrounds the electrical connector elements annularly in cross section, and the electrical device is mounted on an inner side of the flexible carrier which faces the connector elements.

Abstract: A shielded electrical cable includes at least two spaced-apart conductors extending side-by-side along a longitudinal cable direction. An insulation electrically insulates the conductors from each other. A cable shield, together with the conductors, extends along the longitudinal cable direction and annularly surrounds the conductors, as seen in cross section. An electrical device is disposed between the conductors and the cable shield. The electrical device is surrounded by the cable shield and disposed on the conductors such that the electrical device is in electrical contact with each of the conductors.

Abstract: Methods and apparatus relating to FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.

Abstract: The invention is directed to nanopore-based methods for analyzing polymers, such as polynucleotides or proteins, containing optical labels specific for different kinds of monomers. In some embodiments, methods of the invention include steps of (a) translocating a polymer through a nanopore, wherein different kinds of monomers of the polymer are labeled with different optical labels that generate distinguishable optical signals and wherein the nanopore constrains the monomers to move single file through an excitation zone that encompasses a plurality of monomers; (b) detecting a time-ordered set of optical signals from the monomers as the polymer passes through the excitation zone; (c) separating optical signals from different kinds of monomers to form monomer-specific time-ordered sets of optical signals; and (d) determining a sequence of monomers from the monomer-specific time-ordered sets of optical signals from the polymer.

Abstract: An interconnection includes a cable assembly and a board assembly. The cable assembly includes a cable having an inner conductor. The board assembly comprises an intermediate layer disposed between first and second outer layers, a recess disposed between the first and second outer layers so as to form a cable-receiving space at a first side edge, and a first inner-conductor contact opening extending through at least one of the first and second outer layers and opening into the cable-receiving space. The inner conductor is inserted at the first side edge into the cable-receiving space and is disposed at an offset in a longitudinal direction relative to the first inner-conductor contact opening. The inner conductor is electrically conductively soldered via a first soldered inner-conductor connection to a first inner-conductor connection region of the first and/or second outer layers, at least in a region of the first inner-conductor contact opening.

Abstract: The invention is directed to devices and methods for optically based nanopore analysis which employ FRET signaling wherein at least one member of a FRET pair is mobile within a lipid bilayer containing one or more nanopores. In some embodiments, mobile FRET donors are constrained to a lipid bilayer so that they may continuously diffuse into and within a FRET distance of acceptor-labeled analytes entering or exiting a nanopore so that bleached or degraded FRET donors are continuously replaced.

Abstract: An electrical device having a housing and a lid which may be placed on the housing. A sealing element is situated in a depression of the housing, in particular the wall of the housing, which is disposed between the housing and the lid. The sealing element has a recess for the feed-through of a cable. The cable is inserted into a curved groove of the housing, especially the wall of the housing. The housing has a claw segment, which hooks and/or cuts into into the shielding of the cable.