Abstract: Some embodiments include compounds that can inhibit the growth of bacterial and/or inhibit or reduce microbial infections caused by one or more microorganisms (e.g., Pseudomonas aeruginosa and Cryptococcus neoformans) and methods of using these compounds to treat microbial infection and outbreaks and/or to reduce the formation of biofilms. Other embodiments include synthesis of the compounds that can inhibit the growth of one or more microorganisms and/or inhibit or reduce microbial infections.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium for access control for enterprise information. In one aspect, a method includes receiving resources of an enterprise, each resource having a respective access control list specifying access privileges to the resource for one or more members, and the resources including entities related to the enterprise and relationships; identifying entity facts of the entities from the resources; determining, for each entity fact, an entity fact access control list; storing data describing the entities, entity facts and the respective entity fact access control lists, wherein each entity fact is associated with its corresponding entity fact access control list; and providing, to each of the members of the enterprise, access privileges to the data describing the entities and the entity facts according to the respective entity fact access control lists.

Abstract: In the context of service and maintenance of heavy road vehicles, apparatus is provided that is configured to engage and support a rack and manoeuvre it into position relative to the vehicle to facilitate removal and installation of the wheels. The rack has a frame with a base and a pair of arms, each arm being pivotally attached to opposite sides of the base to pivot between an open configuration and a folded configuration. The apparatus may be expanded and contracted between an expanded configuration, where the rack engagement assembly is configured to engage the rack in the open configuration, and a contracted configuration where the rack engagement assembly is configured to engage the rack in the folded configuration.

Abstract: A charging system for an electric vehicle is described. The charging system for an electric vehicle can have a power supply, a charging cable, a connector, and a cooling system. The charging cable can have a coolant conduit routed through the charging cable. The charging cable can also have a coolant return path formed within the charging cable jacket. The cooling system can pump coolant through the coolant conduit and coolant return path to remove heat from the charging cable during a charging process.

Abstract: A system for removing and reinstalling a heavy vehicle brake assembly, including: a calliper support assembly configured to engage and support an in-situ calliper, the calliper support assembly being liftable and retractable from the vehicle with the calliper engaged to remove and subsequently reengage a calliper with the hub assembly; a hub engagement assembly configured to engage an accessible portion of an in-situ hub and rotor assembly, the hub engagement assembly being configured to support and move the engaged hub and rotor assembly between an in-situ position and a removed position for removal and reinstallation of the hub and rotor assembly; and means within the system for manoeuvring the brake assembly to facilitate servicing.

Abstract: A method of printing composition(s) on a web is disclosed. The method includes the steps of advancing the web and printing a plurality of composition sites on the web. The method further includes the step of forming one or more discontinuities in the web. The discontinuities correspond to the printed composition sites.

Abstract: Compounds of the general formula): processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

Abstract: An apparatus configured to engage and support a heavy vehicle brake assembly to facilitate removal and installation. The apparatus comprises a drum and hub engagement assembly configured to engage an accessible portion of an in-situ drum and/or hub assembly and to support the drum and/or hub assembly when so engaged for transport between an in-situ position and a removed position. The apparatus includes a lifting assembly having an upright guide assembly and a lifting device for raising and lowering the drum and hub engagement assembly. The lifting device is configured to raise and lower the drum and hub engagement assembly and the drum and/or hub assembly engaged thereby along the upright guide assembly in a vertical line. The apparatus is configured to be positionable relative to the brake assembly and movable away from the vehicle to facilitate removal of the brake assembly.

Abstract: An activator composition for a non-OPC hydraulically-active material comprises CaO or lime and a polycarboxylate-ether-based (PCE) superplasticiser, and is mixable with a hydraulically active material comprising ground granulated blast furnace slag (GGBS) and/or pulverized fuel ash (PFA) to form a cementitious binder. The cementitious binder does not comprise any Portland cement and is, therefore, more environmentally friendly.

Abstract: Glasses are disclosed having a composition comprising the following oxides (in weight %): SiO2 61 to 70%, Al2O3 0 to 9%, Na2O 10 to 13%, K2O 0 to 1%, MgO 2 to 6%, CaO 6 to 16%, SrO 0 to 1%, ZrO2 0 to 1%, TiO2 2 to 15%, the glasses having a strain point greater than 570° C. The glasses have good dimensional stability at high temperatures, making them suitable for fire protection glazings and substrates which are processed at elevated temperatures, e.g. substrates for display panels, information storage discs and semiconductor devices, including photovoltaic cells. Physical properties of the glasses, such as thermal expansion coefficient, density and refractive index, are disclosed, as are the melting and liquidus temperatures. The glasses are suitable for manufacture by the float process, yielding flat glass in the form of sheets.

Abstract: Provided herein are methods of activating immune cells. The method includes providing a population of immune cells and contacting the population of immune cells with a first agent and a second agent. The first agent includes an immune cell activator attached to a first binder moiety, and the second agent includes at least one capture oligomer. The at least one capture oligomer is capable of associating with the first binder moiety. Also provided are kits for activating immune cells.

Abstract: Embodiments of the present invention provide a computer-implemented method of determining temporal behaviour of an object, comprising receiving image data comprising data representing a plurality of images, at least some of the images comprising one or more cells, determining a plurality of characteristics of at least one feature in each of one or more of the plurality of images, determining a confidence value representing a confidence that one of the cells in a first one of the plurality of images corresponds to a feature in a second one of the plurality images, wherein the confidence value is based upon the characteristics of the feature in the second image and the characteristics of the cell, and identifying the cell in the second one of the plurality of images based upon the confidence value.

Abstract: The invention provides a method for laser modification of a sample to form a modified region at a target location within the sample. The method comprises positioning a sample in a laser system for modification by a laser; measuring tilt of a surface of the sample through which the laser focusses; using at least the measured tilt to determine a correction to be applied to an active optical element of the laser system; applying the correction to the active optical element to modify wavefront properties of the laser to counteract an effect of coma on laser focus; and laser modifying the sample at the target location using the laser with the corrected wavefront properties to produce the modified region.

Abstract: A window assembly includes a first pane of glass. The first pane of glass is chemically strengthened and exhibits a surface compressive stress of 400 MPa or more. A second pane of glass has a first major surface and a second major surface. The second major surface of the second pane of glass and a first major surface of the first pane of glass face each other. The second pane of glass includes 68-74 weight % SiO2, 2-6 weight % MgO, 1-10 weight % CaO, 12-16 weight % Na2O, 0-1 weight % K2O, 0.8-2.0 weight % Fe2O3 (total iron), 0-1.25 weight % TiO2, and 0-1.25 weight % CeO2. A polymeric interlayer is provided between the first pane of glass and the second pane of glass. The window assembly exhibits a direct solar transmittance of 55% or less and a total solar transmittance of 65% or less.

Abstract: A method of printing composition(s) on a web is disclosed. The method includes the steps of advancing the web and printing a plurality of composition sites on the web. The method further includes the step of forming one or more discontinuities in the web. The discontinuities correspond to the printed composition sites.

Abstract: Compounds of the general formula (I): or a pharmaceutically acceptable salt thereof, processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

Abstract: The present invention provides full compliance with Texas SB 507 and is a cost-effective drop-in solution requiring very little resources to install and operate. The system may use off-the-shelf components run by proprietary software further reducing initial cost outlays. The system may include an electric source, a computer having a primary storage device powered by the electric source, a backup storage device connected to the computer, a camera for recording audio data and video data and a ceiling box.

Abstract: The present invention discloses compounds according to Formula I: wherein R1 is as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cystic fibrosis by administering a compound of the invention.

Abstract: This invention relates to compounds of general formula (I) in which R1, R2, R3, R4, L, X and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.