Patents by Inventor Masakazu Tanaka

Masakazu Tanaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10272153
    Abstract: The present invention provides: an antibody that has specificity for MUC 4 having a sugar chain structure that is expressed at a high level in cancer cells; a glycopeptide that constitutes an antigen that is suitable for producing this antibody; and a new means and method for the diagnosis, prevention, and/or treatment of cancer by means of the aforementioned antibody. The present invention relates to a monoclonal antibody against a glycopeptide. The glycopeptide comprises a human MUC 4 tandem unit peptide having an amino acid sequence represented by SEQ ID NO: 1, and an O-linked sugar chain. The O-linked sugar chain is N-acetylgalactosamine (GalNAc) and binds to threonine, which is the 8th amino acid of the tandem unit peptide.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: April 30, 2019
    Assignee: MEDICINAL CHEMISTRY PHARMACEUTICALS Co., Ltd.
    Inventors: Shinichiro Nishimura, Risho Miyoshi, Kentaro Naruchi, Masakazu Tanaka
  • Patent number: 10239950
    Abstract: The present invention provides: an antibody exhibiting specificity for MUC1, the antibody having a glycan structure expressed at high levels in cancer cells; a method for manufacturing this antibody; and a novel means and method for the diagnosis and prevention and/or treatment of cancer using this antibody. The present invention is a monoclonal antibody to human MUC1, wherein the antibody specifically recognizes a glycopeptide having a human MUC1 tandem unit and furthermore having an O-linked glycan core (0(Tn)) in any one of the threonine and serine in the amino acid sequence of this human MUC1 tandem unit. A method for detecting MUC1 in a human body-fluid sample. A kit including this monoclonal antibody. A pharmacological composition for the prevention and/or treatment of a malignant tumor, the pharmacological composition containing this monoclonal antibody as an active ingredient.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: March 26, 2019
    Assignee: MEDICINAL CHEMISTRY PHARMACEUTICALS, Co., Ltd.
    Inventors: Shinichiro Nishimura, Risho Miyoshi, Kentaro Naruchi, Masakazu Tanaka, Masaharu Sato
  • Publication number: 20190048109
    Abstract: A 4-methyl-1-pentene polymer having: a unit derived from 4-methyl-1-pentene of 90 to 100% by mol; a unit selected from ethylene and an ?-olefin, other than 4-methyl-1-pentene, having 3 to 20 carbon atoms of 0 to 10% by mol; and the polymer satisfying the following requirements: (a) a meso diad fraction measured by 13C-NMR within the range of 98 to 100%; (b) a ratio of Z-average molecular weight Mz to weight-average molecular weight Mw measured by GPC within the range of 2.5 to 20; (c) a ratio of weight-average molecular weight Mw to number-average molecular weight Mn measured by GPC within the range of 3.6 to 30; (d) a melt flow rate measured under conditions of 260° C. and a 5 kg load (ASTM D1238) within the range of 0.1 to 500 g/10 min; and (e) an amount of a decane-soluble portion at 23° C. is 5.0% by mass or less.
    Type: Application
    Filed: February 21, 2017
    Publication date: February 14, 2019
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Masakazu TANAKA, Masahiko OKAMOTO, Makoto NAKANO, Sadahiko MATSUURA
  • Patent number: 10072116
    Abstract: The purpose of the present invention is to provide a polar-group-containing propylene-type wax having excellent properties including a low melting point. A modified propylene-(?-olefin) copolymer (A) according to the present invention is produced by grafting at least one compound selected from an unsaturated carboxylic acid, a derivative of the unsaturated carboxylic acid and an unsaturated sulfonic acid salt onto a propylene-(?-olefin) copolymer (A1) and has an acid value of 1 to 100 KOHmg/g, wherein the propylene-(?-olefin) copolymer (A1) comprises 60 to 95 mol % of a propylene-derived constituent unit (a) and 5 to 40 mol % of a constituent unit (b) derived from an ?-olefin having 4 or more carbon atoms, and satisfies the specific requirements (i) to (iii).
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: September 11, 2018
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Kuniaki Kawabe, Hirotaka Kanaya, Masakazu Tanaka, Toshiyuki Ito, Masako Yoshida
  • Patent number: 10072171
    Abstract: The present invention relates to an olefin-based paint. The purpose of the present invention is to provide a paint with excellent organic solvent solubility or dispersibility, low paint viscosity, minimal coating irregularities even at high concentrations, excellent handling and storage stability, and excellent blocking resistance and coated film stability. In order to meet this purpose, an olefin-based paint is used that is characterized by containing a solution or dispersion obtained by dissolving or dispersing 0.1-55 parts by mass of a propylene-?-olefin copolymer (A) for 100 parts by mass of an organic solvent. The copolymer (A) is characterized by containing 60-90 mol % of propylene-derived constituent units (a) having a weight-average molecular weight (Mw), measured by GPC, in the range of 3,000 to 40,000, and 10-40 mol % of ?-olefin-derived constituent units (b) having 4 or more carbon atoms [wherein (a)+(b)=100 mol %].
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: September 11, 2018
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Kuniaki Kawabe, Hirotaka Kanaya, Masakazu Tanaka, Toshiyuki Ito
  • Patent number: 10053562
    Abstract: Provided is a resin composition which contains (A) a polyethylene wax satisfying the requirements (i)-(iv) described below and (B) at least one resin selected from the group consisting of thermoplastic resins and thermosetting resins, wherein the mass ratio of (A) to (B) is from 0.1/99.9 to 50/50. This resin composition is useful for providing a toner which can be fixed by means of a relatively-low-temperature heating body and has good offset resistance, and which is suppressed in increase of particle diameters even if the toner is stored for a long period of time. (i) The weight average molecular weight (Mw) is within the range from 400 to 1,500. (ii) The molecular weight distribution (Mw/Mn) is within the range from 1.2 to 2.5. (iii) The penetration as measured at 25° C. is 5 dmm or less. (iv) The melting point (Tm) is within the range from 50° C. to 110° C.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: August 21, 2018
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Masakazu Tanaka, Kuniaki Kawabe, Hirotaka Kanaya, Keiichi Taki, Yuichi Kaida
  • Patent number: 9944779
    Abstract: Provided is a resin composition containing: (A) an ethylene/?-olefin copolymer containing 91.0-99.9 parts by mole of (a) an ethylene-derived unit and 0.1-9.0 parts by mole of (b) a C3-C8 ?-olefin-derived unit (wherein (a)+(b) is 100 parts by mole), while satisfying the requirements (i)-(iv) and (B) a thermoplastic resin and/or a thermosetting resin, wherein the mass ratio (A)/(B) is 0.1/99.9 to 50/50. This resin composition is useful for providing a toner which can be fixed by a relatively-low-temperature heating body and has good offset resistance, and which is suppressed in increase of particle diameters even if the toner is stored for a long time. (i) The Mw is 400 to 1,500. (ii) The Mw/Mn is 1.2 to 2.5. (iii) The penetration measured at 25° C. is 13 dmm or less. (iv) The melting temperature is 50° C. to 110° C.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: April 17, 2018
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Masakazu Tanaka, Kuniaki Kawabe, Hirotaka Kanaya, Keiichi Taki, Yuichi Kaida
  • Publication number: 20170198056
    Abstract: The present invention provides: an antibody exhibiting specificity for MUC1, the antibody having a glycan structure expressed at high levels in cancer cells; a method for manufacturing this antibody; and a novel means and method for the diagnosis and prevention and/or treatment of cancer using this antibody. The present invention is a monoclonal antibody to human MUC1, wherein the antibody specifically recognizes a glycopeptide having a human MUC1 tandem unit and furthermore having an O-linked glycan core (0(Tn)) in any one of the threonine and serine in the amino acid sequence of this human MUC1 tandem unit. A method for detecting MUC1 in a human body-fluid sample. A kit including this monoclonal antibody. A pharmacological composition for the prevention and/or treatment of a malignant tumor, the pharmacological composition containing this monoclonal antibody as an active ingredient.
    Type: Application
    Filed: April 28, 2015
    Publication date: July 13, 2017
    Inventors: Shinichiro Nishimura, Risho Miyoshi, Kentaro Naruchi, Masakazu Tanaka, Masaharu Sato
  • Publication number: 20170173152
    Abstract: The present invention provides: an antibody that has specificity for MUC 4 having a sugar chain structure that is expressed at a high level in cancer cells; a glycopeptide that constitutes an antigen that is suitable for producing this antibody; and a new means and method for the diagnosis, prevention, and/or treatment of cancer by means of the aforementioned antibody. The present invention relates to a monoclonal antibody against a glycopeptide. The glycopeptide comprises a human MUC 4 tandem unit peptide having an amino acid sequence represented by SEQ ID NO: 1, and an O-linked sugar chain. The O-linked sugar chain is N-acetylgalactosamine (GalNAc) and binds to threonine, which is the 8th amino acid of the tandem unit peptide.
    Type: Application
    Filed: February 5, 2015
    Publication date: June 22, 2017
    Inventors: Shinichiro Nishimura, Risho Miyoshi, Kentaro Naruchi, Masakazu Tanaka
  • Publication number: 20170037229
    Abstract: Provided is a resin composition containing: (A) an ethylene/?-olefin copolymer containing 91.0-99.9 parts by mole of (a) an ethylene-derived unit and 0.1-9.0 parts by mole of (b) a C3-C8 ?-olefin-derived unit (wherein (a)+(b) is 100 parts by mole), while satisfying the requirements (i)-(iv) and (B) a thermoplastic resin and/or a thermosetting resin, wherein the mass ratio (A)/(B) is 0.1/99.9 to 50/50. This resin composition is useful for providing a toner which can be fixed by a relatively-low-temperature heating body and has good offset resistance, and which is suppressed in increase of particle diameters even if the toner is stored for a long time. (i) The Mw is 400 to 1,500. (ii) The Mw/Mn is 1.2 to 2.5. (iii) The penetration measured at 25° C. is 13 dmm or less. (iv) The melting temperature is 50° C. to 110° C.
    Type: Application
    Filed: April 17, 2015
    Publication date: February 9, 2017
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Masakazu TANAKA, Kuniaki KAWABE, Hirotaka KANAYA, Keiichi TAKI, Yuichi KAIDA
  • Publication number: 20170037227
    Abstract: Provided is a resin composition which contains (A) a polyethylene wax satisfying the requirements (i)-(iv) described below and (B) at least one resin selected from the group consisting of thermoplastic resins and thermosetting resins, wherein the mass ratio of (A) to (B) is from 0.1/99.9 to 50/50. This resin composition is useful for providing a toner which can be fixed by means of a relatively-low-temperature heating body and has good offset resistance, and which is suppressed in increase of particle diameters even if the toner is stored for a long period of time. (i) The weight average molecular weight (Mw) is within the range from 400 to 1,500. (ii) The molecular weight distribution (Mw/Mn) is within the range from 1.2 to 2.5. (iii) The penetration as measured at 25° C. is 5 dmm or less. (iv) The melting point (Tm) is within the range from 50° C. to 110° C.
    Type: Application
    Filed: April 17, 2015
    Publication date: February 9, 2017
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Masakazu TANAKA, Kuniaki KAWABE, Hirotaka KANAYA, Keiichi TAKI, Yuichi KAIDA
  • Publication number: 20160280828
    Abstract: The purpose of the present invention is to provide a polar-group-containing propylene-type wax having excellent properties including a low melting point. A modified propylene-(?-olefin) copolymer (A) according to the present invention is produced by grafting at least one compound selected from an unsaturated carboxylic acid, a derivative of the unsaturated carboxylic acid and an unsaturated sulfonic acid salt onto a propylene-(?-olefin) copolymer (A1) and has an acid value of 1 to 100 KOHmg/g, wherein the propylene-(?-olefin) copolymer (A1) comprises 60 to 95 mol % of a propylene-derived constituent unit (a) and 5 to 40 mol % of a constituent unit (b) derived from an ?-olefin having 4 or more carbon atoms, and satisfies the specific requirements (i) to (iii).
    Type: Application
    Filed: November 5, 2014
    Publication date: September 29, 2016
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Kuniaki KAWABE, Hirotaka KANAYA, Masakazu TANAKA, Toshiyuki ITO, Masako YOSHIDA
  • Publication number: 20160160044
    Abstract: Problem to be solved by the present invention is to provide a molding resin composition containing an inorganic reinforcing material which enables a molded body having excellent impact resistance, high surface glossiness, and good mold releasability. This problem is solved by a molding resin composition comprising: 94 to 49 parts by weight of at least one resin (A) selected from a thermoplastic resin and a thermosetting resin; 5 to 50 parts by weight of an inorganic reinforcing material (B); 1 to 46 parts by weight of a functional group-containing olefin polymer (C) containing a component having a Tg of ?140° C. to 0° C. (total of the components (A), (B) and (C) being 100 parts by weight), and 0.01 to 10 parts by weight of an olefin wax (D) having an oxygen- or nitrogen-containing group, the weight ratio C/D of component C to component D being 0.1 to 30.
    Type: Application
    Filed: June 23, 2014
    Publication date: June 9, 2016
    Applicant: Mitsui Chemicals. Inc.
    Inventors: Hirotaka KANAYA, Kuniaki KAWABE, Masakazu TANAKA
  • Publication number: 20160115334
    Abstract: The present invention relates to an olefin-based paint. The purpose of the present invention is to provide a paint with excellent organic solvent solubility or dispersibility, low paint viscosity, minimal coating irregularities even at high concentrations, excellent handling and storage stability, and excellent blocking resistance and coated film stability. In order to meet this purpose, an olefin-based paint is used that is characterized by containing a solution or dispersion obtained by dissolving or dispersing 0.1-55 parts by mass of a propylene-?-olefin copolymer (A) for 100 parts by mass of an organic solvent. The copolymer (A) is characterized by containing 60-90 mol % of propylene-derived constituent units (a) having a weight-average molecular weight (Mw), measured by GPC, in the range of 3,000 to 40,000, and 10-40 mol % of ?-olefin-derived constituent units (b) having 4 or more carbon atoms [wherein (a)+(b)=100 mol %].
    Type: Application
    Filed: June 6, 2014
    Publication date: April 28, 2016
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Kuniaki KAWABE, Hirotaka KANAYA, Masakazu TANAKA, Toshiyuki ITO
  • Patent number: 9323166
    Abstract: The present invention addresses the problem of providing an electrophotographic toner which has excellent storage property, is excellent in offset resistance and low-temperature fixing property during printing and has few substances causing staining with time, odor or dust inside a copy machine or a printer. The present invention relates to an electrophotographic toner characterized by containing an ethylene copolymer which comprises a constituent unit (a) derived from ethylene in an amount of 80 to 99.5% by mol and a constituent unit (b) derived from a cyclic olefin of 8 or more carbon atoms in an amount of 0.5 to 20% by mol [(a)+(b)=100% by mol] and satisfies the requirements: (i) the intrinsic viscosity [?] is in the range of 0.01 to 0.50 dl/g, and (ii) the crystallinity is in the range of 50 to 90%.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: April 26, 2016
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Kuniaki Kawabe, Masakazu Tanaka, Hiroshi Matsuoka, Noriko Kai, Keiichi Taki
  • Patent number: 9010295
    Abstract: An intake system for an internal combustion engine, having a structure in which blow-by oil and/or fuel entering into an air cleaner case can be discharged to the outside of the air cleaner case. The intake system for an internal combustion engine is provided in which air is sucked from a clean air chamber in the air cleaner case into a throttle body provided with a throttle valve through a funnel while defining an airflow passage. Concurrently, fuel is sprayed from an injector, thereby feeding the fuel-air mixture into an intake port. A bypass passage different from the airflow passage is provided between the clean air chamber in the air cleaner case and the throttle body. The bypass passage is so structured that a passage inlet thereof on the clean air chamber side opens at an inner wall surface of the air cleaner case.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: April 21, 2015
    Assignee: Honda Motor Co., Ltd.
    Inventors: Naoto Yamagishi, Masakazu Tanaka
  • Publication number: 20150044603
    Abstract: The present invention addresses the problem of providing an electrophotographic toner which has excellent storage property, is excellent in offset resistance and low-temperature fixing property during printing and has few substances causing staining with time, odor or dust inside a copy machine or a printer. The present invention relates to an electrophotographic toner characterized by containing an ethylene copolymer which comprises a constituent unit (a) derived from ethylene in an amount of 80 to 99.5% by mol and a constituent unit (b) derived from a cyclic olefin of 8 or more carbon atoms in an amount of 0.5 to 20% by mol [(a)+(b)=100% by mol] and satisfies the requirements: (i) the intrinsic viscosity [?] is in the range of 0.01 to 0.50 dl/g, and (ii) the crystallinity is in the range of 50 to 90%.
    Type: Application
    Filed: March 22, 2013
    Publication date: February 12, 2015
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Kuniaki Kawabe, Masakazu Tanaka, Hiroshi Matsuoka, Noriko Kai, Keiichi Taki
  • Patent number: 8670700
    Abstract: A developing roller is provided, which is particularly used in an image forming apparatus of a highly durable design and is free from toner leakage even after formation of a predetermined number of images. Opposite end regions (5a) of an outer peripheral surface (5) of a roller body (2) of the developing roller (1) to be respectively kept in sliding contact with seal members each have a friction coefficient ? of not greater than 0.15.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: March 11, 2014
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Kenichi Kuroda, Akihiko Kawatani, Masakazu Tanaka, Yoshihisa Mizumoto
  • Publication number: 20130089362
    Abstract: A developing roller is provided, which is particularly used in an image forming apparatus of a highly durable design and is free from toner leakage even after formation of a predetermined number of images. Opposite end regions (5a) of an outer peripheral surface (5) of a roller body (2) of the developing roller (1) to be respectively kept in sliding contact with seal members each have a friction coefficient ? of not greater than 0.15.
    Type: Application
    Filed: July 27, 2012
    Publication date: April 11, 2013
    Inventors: Kenichi KURODA, Akihiko Kawatani, Masakazu Tanaka, Yoshihisa Mizumoto
  • Publication number: 20120180746
    Abstract: An intake system for an internal combustion engine, having a structure in which blow-by oil and/or fuel entering into an air cleaner case can be discharged to the outside of the air cleaner case. The intake system for an internal combustion engine is provided in which air is sucked from a clean air chamber in the air cleaner case into a throttle body provided with a throttle valve through a funnel while defining an airflow passage. Concurrently, fuel is sprayed from an injector, thereby feeding the fuel-air mixture into an intake port. A bypass passage different from the airflow passage is provided between the clean air chamber in the air cleaner case and the throttle body. The bypass passage is so structured that a passage inlet thereof on the clean air chamber side opens at an inner wall surface of the air cleaner case.
    Type: Application
    Filed: December 27, 2011
    Publication date: July 19, 2012
    Inventors: Naoto Yamagishi, Masakazu Tanaka