Abstract: A motor device includes an electric motor, a control board on which a control circuit controlling the electric motor is mounted, a metal housing supporting a first surface of the control board, a resin cover attached to the housing to cover a second surface of the control board opposite to the first surface and the periphery of the control board, and a heat dissipation member dissipating heat generated by a heating element included in the control circuit to the housing. The heat dissipation member includes a heat reception plate fixed to the cover, and a heat transfer plate protruding toward the housing. The housing includes, outside the motor accommodation space, a reception portion receiving a protrusion end of the heat transfer plate inserted in a direction in which a rotation shaft extends, and a heat exhaust wall extending in the and coming into surface contact with the heat transfer plate.

Abstract: A control device includes a control board on which a control circuit for controlling an electric motor is mounted, a housing that supports a surface on a side of the control board in a thickness direction, and a cover attached to the housing to cover a surface on the other side of the control board in the thickness direction and a periphery of the control board. First positioning holes penetrating in the thickness direction are formed in the control board. Second positioning holes respectively corresponding to the first positioning holes are formed in the housing. The cover includes positioning pins that protrude toward the housing and have a tapered shape in which a diameter of a circumscribed circle gradually decreases toward a tip. The positioning pin is inserted into the first positioning hole and the second positioning hole corresponding thereto to position the control board, the housing, and the cover.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: An arithmetic operation device includes a performance calculation unit that is configured to calculate performance of a plant before introduction of a part and the performance of the plant after the introduction of the part for each of combinations of a plurality of loads in the plant and a plurality of atmospheric temperatures around the plant, a storage unit that is configured to store a data table indicating a percentage of an operating time of the plant for each of the combinations, and a performance improvement calculation unit that is configured to calculate, on the basis of a calculation result in the performance calculation unit and the data table, how much the performance of the plant is improved compared with the performance before the introduction of the part in a case where the part is introduced and the plant is operated at the percentage indicated by the data table.

Abstract: An organic light-emitting device including a compound represented by each of the following formulas has excellent luminescence characteristics. One of X1 and X2 is N, and the other is B; R1 to R26, A1, and A2 are H, D, or a substituent; one of R112 and R113 is CN or a triazinyl group; and the other one, R111, R114, and R115 are H, D, a donor group having a substituted amino group, or an aryl group, but at least one thereof is a substituted or ring-condensed carbazole-9-yl group.

Abstract: A biosensing platform capable of high throughput mechanochemical biosensing comprising a DNA origami nanostructure having a plurality of slots into which recognition elements are strategically placed and apparatus that senses a change in the origami nanostructure in response to the introduction of a target where the apparatus includes a signal transduction unit and signal sensor which exploits mechanical signals in a recognition element which signal includes one or more mechanical tension or mechanochemical rearrangement event. The nanostructure is preferably a 2-dimensional or 3-dimensional arrangement of tiles linked by locking elements, such as aptamers that will open in response to an event such as exposure to a drug molecule, DNA, RNA or protein target.

Abstract: A suture needle for uterine hemostatic compression comprises at least one suture needle and a suture thread. The at least one suture needle includes a body portion extending linearly in a lengthwise direction and a puncture portion provided at a tip of the body portion in the lengthwise direction to be thrust into a uterus. The suture thread is attached to a base end portion that is on an opposite side of the puncture portion in the suture needle. The puncture portion is formed as a spherical surface that bulges toward a tip side of the lengthwise direction. The spherical surface has a radius in a connection portion with the body portion substantially identical to a radius of the body portion.

Abstract: An imaging apparatus of an embodiment of the present invention includes an imaging means (an imaging unit), and a CPU that is configured to perform orientation detection (an orientation detecting unit) to detect an orientation of the imaging apparatus, perform subject detection (a detecting unit) to detect a subject in a detection area (a detection area in a live view image) in an image captured by the imaging means (the live view image), and perform position change (a position changing unit) to change the position of the detection area in the image according to the detected orientation of the imaging apparatus.

Abstract: An imaging apparatus of an embodiment of the present invention includes a detecting unit 4d for detecting a state in a detection area T within an image displayed in a display panel 8a, an identifying unit 4b for identifying a subject from the image, an acquiring unit 4c for acquiring information relating to a predetermined subject in the case that the identifying unit 4b identifies the predetermined subject outside the detection area T, and a control unit (the detecting unit 4d) for controlling detection of the state in the detection area T based on the information relating to the predetermined subject acquired by the acquiring unit 4c.

Abstract: A method of manufacturing a steel wire material that contains 0.05%-1.2% C (“%” means “% by mass,” same hereinafter for chemical components.), 0.01%-0.7% Si, 0.1%-1.5% Mn, 0.02% max. P (not including 0%), 0.02% max. S (not including 0%), and 0.005% max. N (not including 0%), with the remainder being iron and unavoidable impurities. The steel wire material has a scale 6.0-20 ?m thick and holes of an equivalent circle diameter of 1 ?m max. in said scale that occupy 10% by area max. Said scale does not detach in the cooling process after hot rolling or during storage or transportation but can readily detach during mechanical descaling.

Abstract: A biosensing platform capable of high throughput mechanochemical biosensing comprising a DNA origami nanostructure having a plurality of slots into which recognition elements are strategically placed and apparatus that senses a change in the origami nanostructure in response to the introduction of a target where the apparatus includes a signal transduction unit and signal sensor which exploits mechanical signals in a recognition element which signal includes one or more mechanical tension or mechanochemical rearrangement event. The nanostructure is preferably a 2-dimensional or 3-dimensional arrangement of tiles linked by locking elements, such as aptamers that will open in response to an event such as exposure to a drug molecule, DNA, RNA or protein target.

Abstract: An imaging apparatus of an embodiment of the present invention includes an imaging means (an imaging unit), and a CPU that is configured to perform orientation detection (an orientation detecting unit) to detect an orientation of the imaging apparatus, perform subject detection (a detecting unit) to detect a subject in a detection area (a detection area in a live view image) in an image captured by the imaging means (the live view image), and perform position change (a position changing unit) to change the position of the detection area in the image according to the detected orientation of the imaging apparatus.

Abstract: An imaging apparatus of an embodiment of the present invention includes a detecting unit 4d for detecting a state in a detection area T within an image displayed in a display panel 8a, an identifying unit 4b for identifying a subject from the image, an acquiring unit 4c for acquiring information relating to a predetermined subject in the case that the identifying unit 4b identifies the predetermined subject outside the detection area T, and a control unit (the detecting unit 4d) for controlling detection of the state in the detection area T based on the information relating to the predetermined subject acquired by the acquiring unit 4c.

Abstract: A method of manufacturing a steel wire material that contains 0.05%-1.2% C (“%” means “% by mass,” same hereinafter for chemical components.), 0.01%-0.7% Si, 0.1%-1.5% Mn, 0.02% max. P (not including 0%), 0.02% max. S (not including 0%), and 0.005% max. N (not including 0%), with the remainder being iron and unavoidable impurities. The steel wire material has a scale 6.0-20 ?m thick and holes of an equivalent circle diameter of 1 ?m max. in said scale that occupy 10% by area max. Said scale does not detach in the cooling process after hot rolling or during storage or transportation but can readily detach during mechanical descaling.

Abstract: An ozone generating apparatus for making a temperature distribution in a dielectric tube more uniform including a sealed vessel, two tube sheets made of a conductive metal plate having a hole formed therein which are provided at a predetermined interval to divide the inside of the sealed vessel into three spaces; a metal tube formed so as to connect holes of the tow tube sheets, a dielectric tube which is inserted into the inner part of a dielectric tube so as to have a predetermined gap between an outer wall an inner wall of a metal tube and a metal electrode formed inside the dielectric tube. An alternating current voltage is applied between the tube and electrode, a gas including oxygen flowing in a gap is discharged to generate ozone, and a discharge suppressing member is provided at a part of the gap facing a tube sheet.

Abstract: This steel wire material contains 0.05%-1.2% C (“%” means “% by mass,” same hereinafter for chemical components.), 0.01%-0.7% Si, 0.1%-1.5% Mn, 0.02% max. P (not including 0%), 0.02% max. S (not including 0%), and 0.005% max. N (not including 0%), with the remainder being iron and unavoidable impurities. The steel wire material has a scale 6.0-20 ?m thick and holes of an equivalent circle diameter of 1 ?m max. in said scale that occupy 10% by area max. Said scale does not detach in the cooling process after hot rolling or during storage or transportation but can readily detach during mechanical descaling.