Abstract: An automated system that selects an optimal combination of risk models for a target patient population. The selected combination may be monitored by clinicians to determine which patients are at greatest risk for adverse events or clinical deterioration. The system may compare risk model data for hundreds or thousands of models to data collected on a target patient population to determine which combination of models is the best fit for this target group. An illustrative selection method may minimize a cost function that measures the deviation between a model combination and desired features for an optimal combination. Illustrative factors in the cost function may include differences between the predicted risk distributions for the target group, using the model risk function, and the risk distributions for the dataset used to train the model, and correlation among risks predicted by the models in the combination.

Abstract: The present invention relates to methods for extracting nucleic acids from a sample comprising one or more cells. The methods comprise steps of lysing and mechanically disrupting cells in order to provide optimum parallel extraction of both DNA and RNA from samples. The invention also relates to methods of identifying pathogens and organism profiling of samples.

Abstract: In an aspect, a lithium-ion battery anode composition comprises a porous composite particle comprising carbon (C) and an active material comprising silicon (Si), wherein the carbon is characterized by a domain size (r), as estimated from an atomic pair distribution function G(r) obtained from a synchrotron x-ray diffraction measurement of the porous composite particle, ranging from around 10 ? (1 nm) to around 60 ? (6 nm). In a further aspect, a carbon material for use in making an anode composition for use in a Li-ion battery is characterized by a domain size (r), as estimated from an atomic pair distribution function G(r) obtained from a synchrotron x-ray diffraction measurement of the carbon material, ranging from around 10 ? (1 nm) to around 60 ? (6 nm).

Abstract: An automated system that selects an optimal combination of risk models for a target patient population. The selected combination may be monitored by clinicians to determine which patients are at greatest risk for adverse events or clinical deterioration. The system may compare risk model data for hundreds or thousands of models to data collected on a target patient population to determine which combination of models is the best fit for this target group. An illustrative selection method may minimize a cost function that measures the deviation between a model combination and desired features for an optimal combination. Illustrative factors in the cost function may include differences between the predicted risk distributions for the target group, using the model risk function, and the risk distributions for the dataset used to train the model, and correlation among risks predicted by the models in the combination.

Abstract: An assembly includes a fluid conditioning system including a cascade module and an active charge compensator integrated into the fluid conditioning system. The fluid conditioning system is transformable between a first mode and a second mode. In the first mode, the fluid conditioning system includes a first vapor compression loop and a second vapor compression loop. The first vapor compression loop and the second vapor compression loop are thermally coupled at the cascade module and the second vapor compression loop is fluidly separate from the first vapor compression loop. In the second mode, the fluid conditioning system includes a single vapor compression loop. The active charge compensator is operable to control a working fluid charge within the fluid conditioning system based on the mode of operation selected from the plurality of modes.

Abstract: The disclosure provides a control method and a control device for a compressor unit, in which oil levels of a first compressor and a second compressor can be adjusted without additionally arranging an oil return pipeline. A first aspect of this application provides a control method for a compressor unit, the compressor unit having a first compressor and a second compressor, and the first compressor and the second compressor being in communication with each other through a gas balance pipe and an oil balance pipe. The compressor unit has a conventional operation step and an oil level adjustment step that are alternately executed, and in the oil level adjustment step, the compressor unit changes a rotation speed of the first compressor and/or the second compressor to adjust oil levels of the first compressor and the second compressor.

Abstract: The present disclosure relates to methods and materials for assessing and/or treating obese mammals (e.g., obese humans). For example, methods and materials for using one or more interventions (e.g., individualized dietary interventions alone or in combination with pharmacological intervention(s)) to treat obesity and/or obesity-related comorbidities in a mammal (e.g., a human) identified as being likely to respond to a particular intervention (e.g., individualized dietary interventions alone or in combination with pharmacological intervention(s)) are provided.

Abstract: An assembly includes a heat pump and a cascade module fluidly couplable to the heat pump. The cascade module is fluidly connected to the heat pump during a first mode of operation to increase a capacity of the heat pump and the cascade module is not fluidly connected to the heat pump during a second mode of operation.

Abstract: Systems and methods for control optimization of building subsystems are disclosed. In some embodiments, a system comprises at least one processor; and memory storing instructions executable by the at least one processor, the instructions when executed cause the system to: obtain building load information, the building load information related to one or more power consuming subsystems of the building; determine a future building load based on the building load information; and adjust one or more setpoint tolerances for the one or more subsystems based on the determined future building load.

Abstract: Systems and methods of generating music that encodes personalized information implement and/or include generating a personalized sonification model based on music modeling data pertaining to a user; receiving physiological data pertaining to the user, wherein the physiological data is related to at least one of a physical wellness or a behavioral wellness of the user; generating a melody, wherein the melody encodes a wellness information or modification based on the personalized sonification model and the physiological data; and providing the melody to the user to convey the wellness information or modification.

Abstract: We describe a method and system for detecting pathogens in a sample, particularly an air sample. The method is designed to run in real-time alongside sequencing processing of the sample so that results are quickly available to a user. Each input sequence read in the plurality of sequence reads is compared using a first classification algorithm and assigned to a taxon. An input sequence is classified as potentially pathogenic when the taxon to which the input sequence read is assigned corresponds to a pathogen taxon. Each input sequence read classified as potentially pathogenic is compared using a second classification algorithm to a plurality of target sequences in a second database which is selected based on the pathogen taxon. A confidence score is used as part of the decision-making process to decide if an individual read represents a genuine match to a pathogen.

Abstract: A power module assembly includes a frame assembly and a bus bar assembly. The frame assembly includes an upper frame body and a lower frame body coupled to the upper frame body, at least one of the upper and lower frame bodies including at least one jet orifice formed therethrough, the jet orifice configured to receive coolant at a first end and discharge the coolant at a second end, the upper and lower frame bodies at least partially defining a chamber therebetween. The bus bar assembly is arranged in the chamber and includes a bus bar arranged adjacent to the second end of the jet orifice. The jet orifice is configured to discharge the coolant directly onto the bus bar so as to reduce an operating temperature of the bus bar.

Abstract: A method for developing a remote command data package for a motor vehicle by a central electronic computing device involves the central electronic computing device providing a plurality of templates in a user interface of the central electronic computing device. A single template defines at least one generalized vehicle command. A developer of the remote command data package provides a workflow defining logic for the remote command data package using the user interface. The developer provides the workflow using at least one template of the plurality of templates and the central electronic computing device transforms the workflow into the vehicle command depending on the used template.

Abstract: A rooftop air conditioning unit (RTU) is disclosed. The RTU comprises an absorber configured in a supply airstream, a desorber configured in a regeneration airstream, wherein the desorber is fluidically connected to the absorber via a liquid desiccant system and an interchange heat exchanger. The RTU further comprises a first heat exchanger configured upstream of the absorber in the supply air stream, a second heat exchanger configured upstream of the desorber in the regeneration airstream, wherein the first heat exchanger is fluidically connected to the second heat exchanger via a vapor compression system, and one or more secondary heat exchanger configured between the vapor compression system and the liquid desiccant system, wherein the one or more secondary heat exchangers are operable to control temperature of a desiccant associated with the liquid desiccant system into the absorber and/or into the desorber.

Abstract: A system and method for managing climate in a premises is disclosed. The method includes receiving from a detection means, during a plurality of time periods, signals indicative of one or more persons within the premises; extracting from the received signals, identity of the one or more persons within the premises; receiving, from the one or more persons, respective preferred parameters for climate in the premises; predicting, based on the received signals during the plurality of time periods, presence of one or more persons in a subsequent time period, the corresponding identities of the one or more persons, and the respective preferred parameters for climate in the premises; and operating a climate control unit of the premises, such that, for the subsequent time period, the climate in the premises substantially corresponds with the respective preferred parameters for climate in the premises, of the one or more persons predicted to be in the premises.

Abstract: Provided are embodiments for a system for providing component control over a two-wire connection. The embodiments can include a control unit connected to a power source, a remote unit coupled to the control unit over the two-wire connection, the two-wire connection including a power/communication wire and a common wire, and a bridge-type amplifier configured to receive a power signal from the remote unit, the bridge-type amplifier configured to generate a square wave from the power signal. Also provided are embodiments for a method for providing component control over a two-wire connection.

Abstract: A heating, ventilation, and air conditioning (HVAC) system includes a housing, a plurality of compressors, a condenser, a reheater, and an evaporator arranged in fluid communication. The condenser and the reheater are arranged in parallel and the plurality of compressors are arranged in parallel. A fluid management system is operable to actively manage a flow of a fluid within the HVAC system provided to the reheater.

Abstract: In an aspect, a lithium-ion battery anode composition comprises a porous composite particle comprising carbon (C) and an active material comprising silicon (Si), wherein the carbon is characterized by a domain size (r), as estimated from an atomic pair distribution function G(r) obtained from a synchrotron x-ray diffraction measurement of the porous composite particle, ranging from around 10 ? (1 nm) to around 60 ? (6 nm). In a further aspect, a carbon material for use in making an anode composition for use in a Li-ion battery is characterized by a domain size (r), as estimated from an atomic pair distribution function G(r) obtained from a synchrotron x-ray diffraction measurement of the carbon material, ranging from around 10 ? (1 nm) to around 60 ? (6 nm).

Abstract: The invention is a new and distinct variety of grapevine plant named ‘MN 1369’ that is characterized by its seedless berries (small seed traces only), its berries that are medium in size, its berries with a pleasant tropical fruit flavor, its loose berry clusters, its production of berries on secondary buds, and its berries with adherent skin unless overripe.

Abstract: The invention is a new and distinct variety of grapevine plant named ‘MN 1325’ that is characterized by its berries that have a crunchy texture, its berries that have a mild labrusca flavor, its berries that have a thick skin, its berries that are suitable for use in baked goods, similar to a blueberry, and its seedless berries (only seed traces).