Patents by Inventor Michael E. Silver

Michael E. Silver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260055056
    Abstract: An isothiocyanate functional surfactant containing composition where the isothiocyanate functional surfactant containing composition includes an isothiocyanate functional surfactant where the protonated form of the surfactant includes the structure of formula (IA): wherein R1 includes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N?C?S group.
    Type: Application
    Filed: October 30, 2025
    Publication date: February 26, 2026
    Inventor: Michael E. Silver
  • Patent number: 12466789
    Abstract: A method that includes the step of applying an isothiocyanate functional surfactant containing composition to a skin where the isothiocyanate functional surfactant containing composition includes an isothiocyanate functional surfactant where the protonated form of the surfactant includes the structure of formula (IA): wherein R1 includes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N?C?S group.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: November 11, 2025
    Assignee: The William Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 12310939
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Grant
    Filed: May 15, 2023
    Date of Patent: May 27, 2025
    Assignee: The William Yarbrough Foundation
    Inventor: Michael E. Silver
  • Publication number: 20250161258
    Abstract: A method of treating a skin disease comprising applying a topical composition to a portion of a human's skin having the skin disease wherein topical composition comprises a surfactant or a pharmaceutically acceptable salt thereof, wherein the protonated form of the surfactant is represented by the following chemical structure: wherein X comprises an integer ranging from approximately 1 to approximately 25, and wherein Y comprises an integer ranging from approximately 6 to approximately 25.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventor: Michael E. Silver
  • Publication number: 20250161257
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventor: Michael E. Silver
  • Publication number: 20250161256
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventor: Michael E. Silver
  • Publication number: 20250127749
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Application
    Filed: December 30, 2024
    Publication date: April 24, 2025
    Inventor: Michael E. Silver
  • Publication number: 20250127750
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Application
    Filed: December 30, 2024
    Publication date: April 24, 2025
    Inventor: Michael E. Silver
  • Patent number: 12239626
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Grant
    Filed: April 25, 2023
    Date of Patent: March 4, 2025
    Assignee: The William Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 12178794
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: December 31, 2024
    Assignee: The William Yarbrough Foundation
    Inventor: Michael E. Silver
  • Publication number: 20240279169
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of the surfactant includes the structure of formula (IA): wherein R1 includes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N?C?S group.
    Type: Application
    Filed: August 8, 2022
    Publication date: August 22, 2024
    Inventor: Michael E. Silver
  • Publication number: 20230338324
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MlF cytokine or its biological activity is implicated in the disease or condition.
    Type: Application
    Filed: May 15, 2023
    Publication date: October 26, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230321027
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of the surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Application
    Filed: May 22, 2023
    Publication date: October 12, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230263763
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Application
    Filed: April 25, 2023
    Publication date: August 24, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230255920
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Application
    Filed: April 25, 2023
    Publication date: August 17, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230233505
    Abstract: A method for treating psoriasis including the steps of applying an isothiocyanate functional surfactant to an area affected by psoriasis, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: December 5, 2022
    Publication date: July 27, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230165827
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Application
    Filed: December 5, 2022
    Publication date: June 1, 2023
    Inventor: Michael E. Silver
  • Patent number: 11654129
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: May 23, 2023
    Assignee: THE WILLIAM M YARBROUGH FOUNDATION
    Inventor: Michael E. Silver
  • Patent number: 11648230
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Grant
    Filed: December 13, 2020
    Date of Patent: May 16, 2023
    Assignee: THE WILLIAM M YARBROUGH FOUNDATION
    Inventor: Michael E. Silver
  • Patent number: 11633376
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Grant
    Filed: December 13, 2020
    Date of Patent: April 25, 2023
    Assignee: THE WILLIAM M. YARBROUGH FOUNDATION
    Inventor: Michael E. Silver