Patents by Inventor Michael E. Silver

Michael E. Silver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230338324
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MlF cytokine or its biological activity is implicated in the disease or condition.
    Type: Application
    Filed: May 15, 2023
    Publication date: October 26, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230321027
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of the surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Application
    Filed: May 22, 2023
    Publication date: October 12, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230263763
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Application
    Filed: April 25, 2023
    Publication date: August 24, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230255920
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Application
    Filed: April 25, 2023
    Publication date: August 17, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230233505
    Abstract: A method for treating psoriasis including the steps of applying an isothiocyanate functional surfactant to an area affected by psoriasis, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: December 5, 2022
    Publication date: July 27, 2023
    Inventor: Michael E. Silver
  • Publication number: 20230165827
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Application
    Filed: December 5, 2022
    Publication date: June 1, 2023
    Inventor: Michael E. Silver
  • Patent number: 11654129
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: May 23, 2023
    Assignee: THE WILLIAM M YARBROUGH FOUNDATION
    Inventor: Michael E. Silver
  • Patent number: 11648230
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Grant
    Filed: December 13, 2020
    Date of Patent: May 16, 2023
    Assignee: THE WILLIAM M YARBROUGH FOUNDATION
    Inventor: Michael E. Silver
  • Patent number: 11633375
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Grant
    Filed: December 13, 2020
    Date of Patent: April 25, 2023
    Assignee: THE WILLIAM M. YARBROUGH FOUNDATION
    Inventor: Michael E. Silver
  • Patent number: 11633376
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Grant
    Filed: December 13, 2020
    Date of Patent: April 25, 2023
    Assignee: THE WILLIAM M. YARBROUGH FOUNDATION
    Inventor: Michael E. Silver
  • Publication number: 20230110036
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of the surfactant includes the structure of formula (IA): wherein R1 includes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N?C?S group.
    Type: Application
    Filed: August 8, 2022
    Publication date: April 13, 2023
    Inventor: Michael E. Silver
  • Publication number: 20220388954
    Abstract: A method that includes the step of applying an isothiocyanate functional surfactant containing composition to a skin where the isothiocyanate functional surfactant containing composition includes an isothiocyanate functional surfactant where the protonated form of the surfactant includes the structure of formula (IA): wherein R1 includes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N?C?S group.
    Type: Application
    Filed: August 9, 2022
    Publication date: December 8, 2022
    Inventor: Michael E. Silver
  • Patent number: 11517553
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: December 6, 2022
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 11517552
    Abstract: A method for treating psoriasis including the steps of applying an isothiocyanate functional surfactant to an area affected by psoriasis, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: December 6, 2022
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 11407713
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of the surfactant includes the structure of formula (IA): wherein R1 includes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N?C?S group.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: August 9, 2022
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 11339125
    Abstract: The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers and/or activity modifiers.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: May 24, 2022
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 11306057
    Abstract: The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: April 19, 2022
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Publication number: 20220106268
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: May 12, 2020
    Publication date: April 7, 2022
    Inventor: Michael E. Silver
  • Patent number: 11279674
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: March 22, 2022
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Publication number: 20210355081
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: May 12, 2020
    Publication date: November 18, 2021
    Inventor: Michael E. Silver