Patents by Inventor Michael E. Silver

Michael E. Silver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TREATING INFECTIOUS DISEASES WITH ISOTHIOCYANATE FUNCTIONAL COMPOUNDS
    Publication number: 20210244701
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Application
    Filed: December 13, 2020
    Publication date: August 12, 2021
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE
    Publication number: 20210244702
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Application
    Filed: January 5, 2021
    Publication date: August 12, 2021
    Inventor: Michael E. Silver
  • METHOD FOR TREATING RHEUMATOID ARTHRITIS
    Publication number: 20210236453
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an sothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Application
    Filed: December 13, 2020
    Publication date: August 5, 2021
    Inventor: Michael E. Silver
  • METHOD FOR TREATING METASTATIC PROSTATE CANCER
    Publication number: 20210228528
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Application
    Filed: December 13, 2020
    Publication date: July 29, 2021
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL COMPOUNDS AUGMENTED WITH SECONDARY ANTINEOPLASTIC MEDICAMENTS AND ASSOCIATED METHODS FOR TREATING NEOPLASMS
    Publication number: 20210030710
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Application
    Filed: September 8, 2020
    Publication date: February 4, 2021
    Inventor: Michael E. Silver
  • METHOD FOR TREATING PSORIASIS
    Publication number: 20210030709
    Abstract: A method for treating psoriasis including the steps of applying an isothiocyanate functional surfactant to an area affected by psoriasis, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: September 3, 2020
    Publication date: February 4, 2021
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING ISOTHIOCYANATE FUNCTIONAL SURFACTANTS AND ASSOCIATED METHODS FOR TREATING BIOFILMS
    Publication number: 20210024463
    Abstract: The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms.
    Type: Application
    Filed: May 19, 2020
    Publication date: January 28, 2021
    Inventor: Michael E. Silver
  • USE OF ISOTHIOCYANATE FUNCTIONAL SURFACTANTS AS NRF2 INDUCERS TO TREAT EPIDERMOLYSIS BULLOSA SIMPLEX AND RELATED DISEASES
    Publication number: 20210017130
    Abstract: The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers and/or activity modifiers.
    Type: Application
    Filed: May 5, 2020
    Publication date: January 21, 2021
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
    Patent number: 10888540
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: January 12, 2021
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Inhibitors of macrophage migration inhibitory factor
    Patent number: 10874630
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: December 29, 2020
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Method for treating skin cancer
    Patent number: 10869854
    Abstract: A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: December 22, 2020
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer
    Patent number: 10869855
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: December 22, 2020
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Method for treating infectious diseases with isothiocyanate functional compounds
    Patent number: 10864187
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Grant
    Filed: June 26, 2019
    Date of Patent: December 15, 2020
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms
    Patent number: 10765656
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: September 8, 2020
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • METHOD FOR TREATING BENIGN PROSTATIC HYPERPLASIA (BPH), PROSTATITIS, AND PROSTATE CANCER
    Publication number: 20200206179
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Application
    Filed: March 10, 2020
    Publication date: July 2, 2020
    Inventor: Michael E. Silver
  • INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR
    Publication number: 20200206180
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Application
    Filed: March 10, 2020
    Publication date: July 2, 2020
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL COMPOUNDS AUGMENTED WITH SECONDARY ANTINEOPLASTIC MEDICAMENTS AND ASSOCIATED METHODS FOR TREATING NEOPLASMS
    Publication number: 20200179324
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Application
    Filed: February 18, 2020
    Publication date: June 11, 2020
    Inventor: Michael E. Silver
  • Method for Treating Skin Cancer
    Publication number: 20200170989
    Abstract: A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: November 12, 2019
    Publication date: June 4, 2020
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms
    Patent number: 10654799
    Abstract: The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: May 19, 2020
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactant and associated method of use
    Patent number: 10647668
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: May 12, 2020
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver