Patents by Inventor Michael E. Silver

Michael E. Silver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating infectious diseases with isothiocyanate functional compounds
    Patent number: 10335387
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: July 2, 2019
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactant and associated method of use
    Patent number: 10308600
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: June 4, 2019
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
    Patent number: 10308599
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of the surfactant includes the structure of formula (IA): wherein R1 includes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one—N?C?S group.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: June 4, 2019
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms
    Patent number: 10287246
    Abstract: The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: May 14, 2019
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms
    Patent number: 10273205
    Abstract: The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: April 30, 2019
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL COMPOUNDS AUGMENTED WITH SECONDARY ANTINEOPLASTIC MEDICAMENTS AND ASSOCIATED METHODS FOR TREATING BENIGN NEOPLASMS, IN SITU NEOPLASMS, MALIGNANT NEOPLASMS, AND NEOPLASMS OF UNCERTAIN OR UNKNOWN BEHAVIOR
    Publication number: 20190111018
    Abstract: A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.
    Type: Application
    Filed: December 11, 2018
    Publication date: April 18, 2019
    Inventor: Michael E. Silver
  • USE OF ISOTHIOCYANATE FUNCTIONAL SURFACTANTS AS NRF2 INDUCERS TO TREAT EPIDERMOLYSIS BULLOSA SIMPLEX AND RELATED DISEASES
    Publication number: 20190112263
    Abstract: The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers and/or activity modifiers.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 18, 2019
    Inventor: Michael E. Silver
  • METHOD FOR TREATING INFECTIOUS DISEASES WITH ISOTHIOCYANATE FUNCTIONAL COMPOUNDS
    Publication number: 20180311202
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Application
    Filed: July 2, 2018
    Publication date: November 1, 2018
    Inventor: Michael E. Silver
  • Method for treating bladder cancer
    Patent number: 10111852
    Abstract: A method for treating bladder cancer including the steps of administering an isothiocyanate functional surfactant to an area affected by bladder cancer, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: October 30, 2018
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Method for treating eczema
    Patent number: 10111851
    Abstract: A method for treating eczema including the steps of applying an isothiocyanate functional surfactant to an area affected by eczema, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: October 30, 2018
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • METHOD FOR TREATING BENIGN PROSTATIC HYPERPLASIA (BPH), PROSTATITIS, AND PROSTATE CANCER
    Publication number: 20180303785
    Abstract: A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer.
    Type: Application
    Filed: July 2, 2018
    Publication date: October 25, 2018
    Inventor: Michael E. Silver
  • INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR
    Publication number: 20180303786
    Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.
    Type: Application
    Filed: July 2, 2018
    Publication date: October 25, 2018
    Inventor: Michael E. Silver
  • Method for Treating Skin Cancer
    Publication number: 20180289661
    Abstract: A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: April 3, 2018
    Publication date: October 11, 2018
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL SURFACTANT AND ASSOCIATED METHOD OF USE
    Publication number: 20180290972
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Application
    Filed: April 3, 2018
    Publication date: October 11, 2018
    Inventor: Michael E. Silver
  • Method for treating autism and other neurodevelopmental disorders
    Patent number: 10080734
    Abstract: A method for treating autism and other neurodevelopmental disorders including the step of administering an effective amount of an isothiocyanate functional surfactant to a human, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant. The administration of the isothiocyanate functional surfactant may be augmented with a NMDA-receptor antagonist and/or a TNF-? inhibiting agent.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: September 25, 2018
    Assignee: The William M. Yarbrough foundation
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE
    Publication number: 20180256532
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Application
    Filed: May 8, 2018
    Publication date: September 13, 2018
    Inventor: Michael E. Silver
  • ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING ISOTHIOCYANATE FUNCTIONAL SURFACTANTS AND ASSOCIATED METHODS FOR TREATING BIOFILMS
    Publication number: 20180162811
    Abstract: The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms.
    Type: Application
    Filed: February 7, 2018
    Publication date: June 14, 2018
    Inventor: Michael E. Silver
  • Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
    Patent number: 9962361
    Abstract: An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: May 8, 2018
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Method for treating neurodegenerative diseases
    Patent number: 9949943
    Abstract: A method for treating neurodegenerative diseases including the step of administering an isothiocyanate functional surfactant to an area affected by a neurodegenerative disease, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: April 24, 2018
    Assignee: THE WILLIAM M. YARBROUGH FOUNDATION
    Inventor: Michael E. Silver
  • Isothiocyanate functional compound and associated method of use
    Patent number: 9951003
    Abstract: A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: April 24, 2018
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver