Abstract: A sputter-ion-pump system includes a sputter ion pump and an electronic drive. The electronic drive supplies a voltage across the ion pump to establish, in cooperation with a magnetic field, a Penning trap within the ion pump. A current sensor measures the Penning-trap current across the Penning trap. The Penning trap is used as an indication of pressure within the ion pump or a vacuum chamber including or in fluid communication with the ion pump. The pressure information can be used to determine flow rates, e.g., due to a load, outgassing, and/or leakage from an ambient.

Abstract: A monolithic break-seal includes a membrane that separates an outer ring from an inner ring. The inner ring is bonded to a vacuum cell and the outer ring is bonded to a vacuum interface. To protect against unintentional breakage of the membrane, a surface of the outer ring not bonded to the vacuum interface contacts the vacuum cell. An external vacuum system evacuates the vacuum cell through an aperture of the break-seal. Once a target vacuum level is reached for the vacuum cell, a cap is bonded to the inner ring, blocking the aperture and hermetically sealing the vacuum cell. The membrane is broken so that the hermetically sealed vacuum cell can be separated from the vacuum interface to which the outer ring remains bonded.

Abstract: Reversible (relatively weak) anodic bonds permit glass and silicon components to be separated without damaging the components so that they can be reused. To this end, chamfered glass with high aluminum content can be used during the original anodic bonding. Anodic bonding is terminated after complete intimate contact is achieved and while the bond is reversible. The high aluminum content impedes further bond strengthening so that the bond does not become non-reversible via contact bonding. The chamfer provides access near the glass-silicon interface for prying the glass off the silicon to effect debonding without damaging the glass or the silicon. Accordingly, the glass, the silicon, or both may be rebounded (rather than being wastefully disposed).

Abstract: A method and apparatus for centrally managing the performance of maintenance on a fleet of vehicles, the method comprising: acquiring criteria specifying vehicle availability for a predetermined time period; acquiring vehicle data specifying multiple maintenance operations to be performed on one or more of the vehicles; determining, based on the criteria, a fleet plan including, for each vehicle, a schedule of the maintenance operations for that vehicle; determining, using the fleet plan, a maintenance plan comprising, for one or more maintenance service providers, a schedule of maintenance operations to be performed on a vehicle by the maintenance service providers; and managing the maintenance service providers to perform the maintenance operations on the vehicles in accordance with the maintenance plan.

Abstract: A training pistol having an adjustable trigger with a shot-indicating laser to signify the impact of a shot which would simulate a bullet hole of a live fire pistol. In one form a trigger prep indicating system to indicate where the trigger is pressed showing the trigger finger is on the trigger and the trigger is repositioned from a rest state to a position longitudinally rearward therefrom.

Abstract: The present disclosure relates to an apparatus and method that can be used to remotely acquire high resolution depth resolved images from a sample. The apparatus employs an adapter to an imaging device, where the adapter uses a minimum of components to produce interferometry patterns on the input facet of the imaging device. The imaging device can be a bundle endoscope terminated on a camera sensor or on several camera sensors or simply a camera sensor. In conjunction with a swept source or a broadband source, at least one camera sensor may be employed to provide optical coherence tomography (OCT) images of the sample. When the imaging device uses a bundle of optical fibers, the apparatus and method can provide OCT images tolerant to bending of the bundle.

Abstract: Systems, apparatus, methods, and non-transitory media for providing multiple items for purchase to consumers are discussed herein. Some embodiments may include a system including circuitry configured complete a purchase of a first item using transaction data provided the consumer. The circuitry may be further configured to provide additional items to the consumer for a subsequent instant transaction. Using the same transaction data for the instant transaction as the purchase of the first item, the instant transaction may be streamlined by minimizing required consumer inputs. Some embodiments may additionally or alternatively provide for streamlined consumer inputs for the purchase of the first item.

Abstract: Disclosed herein is a lipid nanoparticle (LNP) composition comprising (a) an Akt inhibitor; (b) DSPC; (c) cholesterol; and (d) PEG-DMG. Also disclosed herein is a method for preparing the lipid composition using a scalable tangential flow micro-mixing technology.

Abstract: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.

Abstract: A training pistol having an adjustable trigger with a shot-indicating laser to signify the impact of a shot which would simulate a bullet hole of a live fire pistol. In one form a trigger prep indicating system to indicate where the trigger is pressed showing the trigger finger is on the trigger and the trigger is repositioned from a rest state to a position longitudinally rearward therefrom.

Abstract: Beamformers are formed (e.g., carved) from a stack of transparent sheets. A rear face of each sheet has a reflective coating. The reflectivities of the coatings vary monotonically with sheet position within the stack. The sheets are tilted relative to the intended direction of an input beam and then bonded to form the stack. The carving can include dicing the stack to yield stacklets, and polishing the stacklets to form beamformers. Each beamformer is thus a stack of beamsplitters, including a front beamsplitter in the form of a triangular or trapezoidal prism, and one or more beamsplitters in the form of rhomboid prisms. In use, a beamformer forms an output beam from an input beam. More specifically, the beamformer splits an input beam into plural output beam components that collectively constitute an output beam that differs in cross section from the input beam.

Abstract: Based on a user's current action in an application, a set of the most likely actions to be taken next by a user is determined, such as based on a historical sequence of actions that the user, or a number of other users, have taken in the past. Based on historical sequence of events, a predictive GUI may be generated that can be dynamically updated automatically based on actions that are determined to be undertaken next by the user.

Abstract: A request is received from a security tool, the request relating to an event involving data records in a storage device. An application programming interface (API) is used to interface with secure storage functionality of the storage device, the secure storage functionality enabling a set of secure storage operations. A security operation is caused to be performed at the storage device involving the data records based at least in part on the request. In one aspect, the set of secure storage operations can include a direct read operation, a direct write operation, a copy-on-write operation, and a save-attempted-write operation.

Abstract: An ultra-high vacuum (UHV) system includes a UHV cell and an ion pump to maintain the UHV in the UHV cell. The ion pump has a GCC (glass, ceramic, or crystalline) housing. An interior wall of the ion-pump housing serves as an anode or bears a coating that serves as an anode. At least one cathode is disposed with respect to the housing so that it can cooperate with the anode to form an electric field for establishing a Penning trap. The GCC housing defines a flow channel that extends radially through the anode so that a molecule can flow directly into the most ionizing region of a Penning trap.

Abstract: The present invention relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinase, such as aminopyrazine-isoxazole derivatives and related molecules. The present invention also relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention.

Abstract: A system for providing a solar harvesting building envelope is disclosed. The system includes a plurality of solar harvesting apparatus configured to be installed as or on a building envelope in manner like that of traditional shingles or siding. The apparatus includes a frame having a photovoltaic end wall, as well as reflective base and side walls. A translucent, wedge-shaped body layer is positioned on the frame. A luminescent species film is positioned at and substantially parallel to a base of the wedge-shaped body layer, such that the luminescent species film is positioned at an angle relative to the photovoltaic end wall. Light incident on the wedge-shaped body layer is concentrated towards the photovoltaic end wall, such as through absorption and re-emission along with scattering by the luminescent species film and internal reflection by the wedge-shaped body layer and the reflective base and side walls of the frame.

Abstract: A technique for detecting malware involved loading known malware information, finding a string in the known malware information, saving the string in a first database, identifying a first contiguous string block from the known malware information, assigning a confidence indicator to the first contiguous string block, attempting to find the first contiguous string block in a second database containing one or more contiguous string blocks extracted from known malware, and labelling the first contiguous string block, responsive to a determination the first contiguous string block meets a predetermined threshold of similarity with a second contiguous string block contained in the second database.

Abstract: A request is received from a security tool, the request relating to an event involving data records in a storage device. An application programming interface (API) is used to interface with secure storage functionality of the storage device, the secure storage functionality enabling a set of secure storage operations. A security operation is caused to be performed at the storage device involving the data records based at least in part on the request. In one aspect, the set of secure storage operations can include a direct read operation, a direct write operation, a copy-on-write operation, and a save-attempted-write operation.

Abstract: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.

Abstract: A training pistol having an adjustable trigger with a shot-indicating laser to signify the impact of a shot which would simulate a bullet hole of a live fire pistol. In one form a trigger prep indicating system to indicate where the trigger is pressed showing the trigger finger is on the trigger and the trigger is repositioned from a rest state to a position longitudinally rearward therefrom.