Patents by Inventor Michael Jensen

Michael Jensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for modification of the human glucocorticoid receptor locus
    Publication number: 20080188000
    Abstract: Disclosed herein are methods and compositions for inactivation of the human glucocorticoid receptor (GR) gene by targeted cleavage of genomic DNA encoding the GR. Such methods and compositions are useful, for example, in therapeutic applications which require retention of immune function during glucocorticoid treatment.
    Type: Application
    Filed: November 13, 2007
    Publication date: August 7, 2008
    Inventors: Andreas Reik, Michael Jensen, Michael C. Holmes, Philip D. Gregory, Dale Ando
  • DNA CONSTRUCT ENCODING CE7-SPECIFIC CHIMERIC T CELL RECEPTOR
    Publication number: 20080160607
    Abstract: Genetically engineered, CE7-specific redirected immune cells expressing a cell surface protein having an extracellular domain comprising a receptor which is specific for CE7, an intracellular signaling domain, and a transmembrane domain, and methods of use for such cells for cellular immunotherapy of CE7+ neuroblastoma are disclosed. In one embodiment, the immune cell is a T cell and the cell surface protein is a single chain FvFc: receptor where Fv designates the VH and VL chains of a single chain monoclonal antibody to CE7 linked by peptide, Fc represents a hinge-CH2-CH3 region of a human IgG1, and represents the intracellular signaling domain of the zeta chain of human CD3. DNA constructs encoding a chimeric T-cell receptor and a method of making a redirected T cell expressing a chimeric T cell receptor by electroporation using naked DNA encoding the receptor are also disclosed.
    Type: Application
    Filed: February 8, 2008
    Publication date: July 3, 2008
    Applicant: CITY OF HOPE
    Inventor: Michael JENSEN
  • Method for producing CE7-specific redirected immune cells
    Patent number: 7354762
    Abstract: Genetically engineered, CE7-specific redirected immune cells expressing a cell surface protein having an extracellular domain comprising a receptor which is specific for CE7, an intracellular signaling domain, and a transmembrane domain, and methods of use for such cells for cellular immunotherapy of CE7+ neuroblastoma are disclosed. In one embodiment, the immune cell is a T cell and the cell surface protein is a single chain FvFc:? receptor where Fv designates the VH and VL chains of a single chain monoclonal antibody to CE7 linked by peptide, Fc represents a hinge-CH2-CH3 region of a human IgG1, and ? represents the intracellular signaling domain of the zeta chain of human CD3. DNA constructs encoding a chimeric T-cell receptor and a method of making a redirected T cell expressing a chimeric T cell receptor by electroporation using naked DNA encoding the receptor are also disclosed.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: April 8, 2008
    Assignee: City of Hope
    Inventor: Michael Jensen
  • Seasoning and method for enhancing and potentiating food flavor utilizing microencapsulation while reducing dietary sodium intake
    Publication number: 20080075813
    Abstract: An encapsulated seasoning and method for seasoning for preserving, seasoning, enhancing, and potentiating flavor in a variety of foods and beverages is disclosed. The encapsulated seasoning may include shell and a core, the core comprising at least one seasoning particle having a particle size less than 25 microns and a non-aqueous composition. The encapsulated seasoning particle may include sodium chloride, as a seasoning, and a hydrophobic shell. Encapsulated small sodium chloride may be more effective in delivering taste impact than larger sized sodium chloride. Therefore, less sodium chloride may be required for the same taste effect resulting in less dietary sodium intake.
    Type: Application
    Filed: September 27, 2007
    Publication date: March 27, 2008
    Inventors: Gordon Smith, Michael Jensen
  • COMPOSITIONS THAT CAN PRODUCE POLYMERS
    Publication number: 20080058199
    Abstract: This invention provides a compositions that are useful for polymerizing at least one monomer into at least one polymer.
    Type: Application
    Filed: October 30, 2007
    Publication date: March 6, 2008
    Applicant: PHILLIPS PETROLEUM COMPANY
    Inventors: Max McDaniel, Elizabeth Benham, Shirley Martin, Kathy Collins, James Smith, Gil Hawley, Christopher Wittner, Michael Jensen
  • Polymers Having Broad Molecular Weight Distributions and Methods of Making the Same
    Publication number: 20080051545
    Abstract: Methods of polymerizing at least one olefin include contacting the olefin with a catalyst comprising chromium and with a cocatalyst comprising a non-transition metal cyclopentadienyl (Cp) compound. The polymerization may be performed in the presence of hydrogen. Using the cocatalyst in conjunction with the catalyst increases several properties, such as the high load melt index (HLMI), the MW, and the MN, of the polymers produced by this polymerization method. Polymer compositions produced by such methods have various unique properties, including a PDI greater than about 30. Additional embodiments include articles of manufacture or end use articles formed from such polymer compositions.
    Type: Application
    Filed: October 30, 2007
    Publication date: February 28, 2008
    Applicant: CHEVRON PHILLIPS CHEMICAL COMPANY LP
    Inventors: Max McDaniel, Elizabeth Benham, Steven Secora, Michael Jensen, Kathy Collins
  • Product and method for providing texture, aroma, and flavor to microwave popcorn
    Publication number: 20080044546
    Abstract: A technique and process for preparation of a texturized microwave popcorn product is disclosed. A solid concentrated texturizing composition in a compact form is utilized in a microwavable popcorn bag. The solid concentrated texturizing blend is melted during cooking and dispersed over the popped popcorn as part of the popping process, resulting in a texturized popped microwave popcorn product.
    Type: Application
    Filed: August 17, 2007
    Publication date: February 21, 2008
    Inventors: Michael Jensen, Lance Schilmoeller, Jamie Halgerson, Gordon Smith
  • Seasoning and method for enhancing and potentiating food flavor
    Publication number: 20080038411
    Abstract: A seasoning having particles less than 20 microns in size is added to food to provide taste enhancement and flavor potentiation. In one embodiment, a microwave popcorn product comprising a charge of popcorn kernels, a charge of seasoning for flavoring the charge of kernels, and a bag for containing the charge of seasoning and charge of kernels is disclosed. In another embodiment, the present invention is directed to a seasoning comprising a first seasoning component including a salt and a second seasoning component selected for at least one of complementing the first seasoning component and reducing the amount of the first seasoning component required for flavoring a food product.
    Type: Application
    Filed: February 5, 2007
    Publication date: February 14, 2008
    Inventors: Michael Jensen, Gordon Smith, Shawn Fear, Lance Schilmoeller, Clinton Johnson
  • ACIDIC ACTIVATOR SUPPORTS AND CATALYSTS FOR OLEFIN POLYMERIZATION
    Publication number: 20080026934
    Abstract: This invention relates to the field of olefin polymerization catalyst compositions, and methods for the polymerization and copolymerization of olefins, typically using a supported catalyst composition. In one aspect, this invention encompasses precontacting a metallocene with an olefin or alkyne monomer and an organoaluminum compound, prior to contacting this mixture with the acidic activator-support.
    Type: Application
    Filed: August 27, 2007
    Publication date: January 31, 2008
    Applicant: CHEVRON PHILLIPS CHEMICAL COMPANY
    Inventors: Michael Jensen, Gil Hawley, Max McDaniel, Tony Crain, Elizabeth Benham, Joel Martin, Qing Yang
  • Seasoned food, seasoning, and method for seasoning a food product
    Publication number: 20080008790
    Abstract: A seasoned food product, a seasoning, and a method for seasoning and/or preserving a food product is described in accordance with exemplary embodiments of the present invention. The charge of seasoning has a mean particle size of at least approximately less than 20 microns. In another embodiment, the present invention is a seasoning comprising a first seasoning component including a salt and a second seasoning component selected for at least one of complementing the first seasoning component and reducing the amount of the first seasoning component required for flavoring a food product. The first seasoning component and second seasoning component have a mean particle size of at least approximately less than 20 microns.
    Type: Application
    Filed: February 16, 2007
    Publication date: January 10, 2008
    Inventors: Michael Jensen, Gordon Smith, Shawn Fear, Lance Schilmoeller, Clinton Johnson
  • Polymerization catalysts and process for producing bimodal polymers in a single reactor
    Publication number: 20080004460
    Abstract: Catalyst compositions comprising a first metallocene compound, a second metallocene compound, an activator-support, and an organoaluminum compound are provided. An improved method for preparing cyclopentadienyl complexes used to produce polyolefins is also provided.
    Type: Application
    Filed: February 12, 2007
    Publication date: January 3, 2008
    Applicant: Chevron Phillips Chemical Company, L.P.
    Inventors: Kumudini Jayaratne, Michael Jensen, Qing Yang
  • Seasoning and method for seasoning a food product utilizing small particle sea salt
    Publication number: 20080003339
    Abstract: A method and seasoning including sea salt for flavoring food is disclosed. The sea salt has a mean particle size less than about 20 microns. In another embodiment, the present invention is directed to a seasoning comprising a first seasoning component, including a sea salt, and a second seasoning component selected for at least one of complementing the first seasoning component and reducing the amount of the first seasoning component required for flavoring a food product. The sea salt component has a mean particle size less than 20 microns.
    Type: Application
    Filed: June 20, 2007
    Publication date: January 3, 2008
    Inventors: Clinton Johnson, Michael Jensen, Lance Schilmoeller, Gordon Smith
  • CE7-SPECIFIC REDIRECTED IMMUNE CELLS
    Publication number: 20080003683
    Abstract: Genetically engineered, CE7-specific redirected immune cells expressing a cell surface protein having an extracellular domain comprising a receptor which is specific for CE7, an intracellular signaling domain, and a transmembrane domain, and methods of use for such cells for cellular immunotherapy of CE7+ neuroblastoma are disclosed. In one embodiment, the immune cell is a T cell and the cell surface protein is a single chain FvFc:? receptor where Fv designates the VH and VL chains of a single chain monoclonal antibody to CE7 linked by peptide, Fc represents a hinge-CH2-CH3 region of a human IgG1, and ? represents the intracellular signaling domain of the zeta chain of human CD3. DNA constructs encoding a chimeric T-cell receptor and a method of making a redirected T cell expressing a chimeric T cell receptor by electroporation using naked DNA encoding the receptor are also disclosed.
    Type: Application
    Filed: September 4, 2007
    Publication date: January 3, 2008
    Applicant: CITY OF HOPE
    Inventor: Michael JENSEN
  • Seasoning and method for seasoning a food product while reducing dietary sodium intake
    Publication number: 20080003344
    Abstract: A seasoning for reducing dietary sodium intake is disclosed. The portion of seasoning has a mean particle size of less than or equal to 20 microns. In one embodiment, the invention is a seasoning comprising a first seasoning component including a salt and a second seasoning component selected for at least one of complementing and reducing the amount of the first seasoning component required for flavoring a food product.
    Type: Application
    Filed: February 20, 2007
    Publication date: January 3, 2008
    Inventors: Michael Jensen, Gordon Smith, Shawn Fear, Lance Schilmoeller, Clinton Johnson
  • Polymerization catalysts for producing polymers with low levels of long chain branching
    Publication number: 20070287814
    Abstract: This invention relates to catalyst compositions, methods, and polymers encompassing a Group 4 metallocene with bridging ?5-cyclopentadienyl-type ligands, in combination with a cocatalyst and an activator-support. The compositions and methods disclosed herein provide ethylene polymers with low levels of long chain branching.
    Type: Application
    Filed: December 1, 2006
    Publication date: December 13, 2007
    Applicant: Chevron Phillips Chemical Company, L.P.
    Inventors: Michael Jensen, Joel Martin, Max McDaniel, David Rolfing, Qing Yang, Matthew Thorn, Ashish Sukhadia, Youlu Yu, Jerry Lanier
  • Composition(s) for providing glaze on microwave popcorn, products, and methods
    Publication number: 20070254073
    Abstract: Techniques for preparation of a glazed microwave popcorn product are disclosed. In one embodiment, a glazed microwave popcorn product includes a first package comprising unpopped popcorn for popping in a microwave oven, an oil/fat-based slurry, and a second addition package comprising a glazing blend for adding to the popcorn after popping are described. In another embodiment, a one-step process comprises a charge of microwavable popcorn with a particulate glazing blend included with a charge of unpopped popcorn and a charge of oil/fat-based slurry.
    Type: Application
    Filed: April 19, 2007
    Publication date: November 1, 2007
    Inventors: Michael Jensen, Jody Shands, Jamie Halgerson
  • Polymerization catalysts for producing polymers with low levels of long chain branching
    Publication number: 20070232483
    Abstract: This invention relates to catalyst compositions, methods, and polymers encompassing at least one Group 4 metallocene compound comprising bridging ?5-cyclopentadienyl-type ligands, typically in combination with at least one cocatalyst, and at least one activator. The compositions and methods disclosed herein provide ethylene polymers with low levels of long chain branching.
    Type: Application
    Filed: March 31, 2006
    Publication date: October 4, 2007
    Inventors: Qing Yang, Max McDaniel, Michael Jensen, Matthew Thorn, Joel Martin, Youlu Yu, David Rohlfing
  • INSTRUCTION ENCODING FOR SYSTEM REGISTER BIT SET AND CLEAR
    Publication number: 20070234020
    Abstract: An instruction encoding architecture is provided for a microprocessor to allow atomic modification of privileged architecture registers. The instructions include an opcode that designates to the microprocessor that the instructions are to execute in privileged (kernel) state only, and that the instructions are to communicate with privileged control registers, a field for designating which of a plurality of privileged architecture registers is to be modified, a field for designating which bit fields within the designated privileged architecture register is to be modified, and a field to designate whether the whether the designated bit fields are to be set or cleared. The instruction encoding allows a single instruction to atomically set or clear bit fields within privileged architecture registers, without reading the privileged architecture registers into a general purpose register.
    Type: Application
    Filed: December 6, 2006
    Publication date: October 4, 2007
    Applicant: MIPS TECHNOLOGIES, INC.
    Inventor: Michael Jensen
  • Stabilised solid compositions of factor VII polypeptides
    Publication number: 20070207956
    Abstract: The invention relates to chemically as well as physically stable compositions comprising Factor VII or a Factor VII-related polypeptide such that these compositions can be stored, handled and used at room temperature.
    Type: Application
    Filed: September 25, 2006
    Publication date: September 6, 2007
    Applicant: Novo Nordisk HealthCare A/G
    Inventors: Michael Jensen, Birthe Hansen, Troels Kornfelt
  • CE7-specific chimeric T cell receptor
    Patent number: 7265209
    Abstract: Genetically engineered, CE7-specific redirected immune cells expressing a cell surface protein having an extracellular domain comprising a receptor which is specific for CE7, an intracellular signaling domain, and a transmembrane domain, and methods of use for such cells for cellular immunotherapy of CE7+ neuroblastoma are disclosed. In one embodiment, the immune cell is a T cell and the cell surface protein is a single chain FvFc: ? receptor where Fv designates the VH and VL chains of a single chain monoclonal antibody to CE7 linked by peptide, Fc represents a hinge-CH2-CH3 region of a human IgG1, and ? represents the intracellular signaling domain of the zeta chain of human CD3. DNA constructs encoding a chimeric T-cell receptor and a method of making a redirected T cell expressing a chimeric T cell receptor by electroporation using naked DNA encoding the receptor are also disclosed.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: September 4, 2007
    Assignee: City of Hope
    Inventor: Michael Jensen