Patents by Inventor Michael Nicholas

Michael Nicholas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210281445
    Abstract: In an approach to generating and managing personalized private roaming service set identifiers and networks, one or more computer processors generate one or more private networks based on one or more policies associated with a user and capabilities of one or more network providers in a communication proximity to the user. The one or more computer processors create one or more configuration files required to implement the one or more generated private networks on the one or more network providers. The one or more computer processors implement the one or more generated private networks by applying the one or more created configuration files to the one or more network providers.
    Type: Application
    Filed: March 9, 2020
    Publication date: September 9, 2021
    Inventors: Craig M. Trim, Seng Chai Gan, Shikhar Kwatra, Adam Lee Griffin, Michael Nicholas Virnoche
  • Patent number: 11082283
    Abstract: A method, system, and computer program product for contextual generation of an ephemeral network are provided. The method detects an initiating event for network generation associated with a user of a first computing device. The method determines a duration of the initiating event. A set of network members is determined based on the initiating event and the duration. The method establishes an ephemeral network, connecting at least a portion of computing devices associated with the set of network members. The ephemeral network is terminated in response to detecting a completion event. In response to terminating the ephemeral network, member information for the set of network members is removed from the portion of the computing devices.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: August 3, 2021
    Assignee: International Business Machines Corporation
    Inventors: Craig M. Trim, Shikhar Kwatra, Jennifer Szkatulski, Adam Lee Griffin, Michael Nicholas Virnoche
  • Patent number: 11052086
    Abstract: Methods of using substituted 2-anilinopyrimidine derivatives, and pharmaceutically acceptable salts, solvates, or compositions, for the treatment of brain cancers, in particular EGFR-mediated metastatic brain cancer, are disclosed.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: July 6, 2021
    Assignee: BETA PHARMA, INC.
    Inventors: Michael Nicholas Greco, Michael John Costanzo, Michael Alan Green, Jirong Peng, Victoria Lynn Wilde, Don Zhang
  • Patent number: 11051154
    Abstract: A host computing device receives an advertisement packet via a low-power personal area network and, in response to the advertisement packet, transmits a connection request via the low-power personal area network, pairs via the low-power personal area network and transmits a data message when pairing via the low-power personal area network. The data message instructs a wearable device to pair via a general personal area network.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: June 29, 2021
    Assignee: GOOGLE LLC
    Inventors: Scott Michael Nicholas Greenberg, Jonathan Brubacher, Mark Oliver Slevinsky, Mark P. DiFranco
  • Publication number: 20210177353
    Abstract: A vital signs monitoring ring with integrated display includes a ring housing, the ring housing comprising at least two windows and a printed circuit board assembly (PCBA) layer configured to be attached to the ring housing. The PCBA layer includes a display section, a sensor section, a transmission mode oximetry measurement section configured to be in alignment with the at least two windows, a power supply, and a switch configured to power on the vital signs monitoring ring with integrated display via the power supply. The display section is configured to display physiological and action parameters associated with a user by sensing the physiological and action signals from a digit of user wearing the vital signs monitoring ring with integrated display using at least the sensor section and the transmission mode oximetry measurement section.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 17, 2021
    Applicant: Jabil Inc.
    Inventors: Yusuf Abu Tayeb Bhagat, Girish Satish Wable, Patrick John Verdon, Michael Nicholas Arfaras, Thong Bui, Krishnaveni Das, Sai Guruva Reddy Avuthu, Arnoldo Reta, Jorg Richstein
  • Publication number: 20210177292
    Abstract: A vital signs monitoring patch with integrated display (VSM) includes a user access layer for accessing a display section and a first printed silver-silver chloride (Ag—AgCl) electrode. A polyethylene foam layer including battery and plunger cut-outs. A printed circuit board assembly (PCBA) layer including vitals sign monitoring sensors and the battery and connected to the first and second printed Ag—AgCl electrodes. The polyethylene foam layer bonded to the user access layer and the PCBA layer. A sensor layer including reflection mode oximetry components and the second printed Ag—AgCl electrode. A hydrogel conductive adhesive to interact between a user skin and the second printed Ag—AgCl electrode. A medical tape layer bonded to the user skin and the sensor layer. A plunger connected to the PCBA layer and configured to power on the VSM, where user access of the first printed Ag—AgCl electrode completes a circuit with the second printed Ag—AgCl electrode.
    Type: Application
    Filed: September 18, 2020
    Publication date: June 17, 2021
    Applicant: Jabil Inc.
    Inventors: Yusuf Abu Tayeb Bhagat, Girish Satish Wable, Patrick John Verdon, Michael Nicholas Arfaras, Thong Bui, Krishnaveni Das, Sai Guruva Reddy Avuthu, Arnoldo Reta, Jorg Richstein
  • Publication number: 20210177291
    Abstract: A vital signs monitoring patch with integrated display (VSM) includes a user access layer for accessing a display section and a first printed silver-silver chloride (Ag—AgCl) electrode. A polyethylene foam layer including battery and plunger cut-outs. A printed circuit board assembly (PCBA) layer including vitals sign monitoring sensors and the battery and connected to the first and second printed Ag—AgCl electrodes. The polyethylene foam layer bonded to the user access layer and the PCBA layer. A sensor layer including reflection mode oximetry components and the second printed Ag—AgCl electrode. A hydrogel conductive adhesive to interact between a user skin and the second printed Ag—AgCl electrode. A medical tape layer bonded to the user skin and the sensor layer. A plunger connected to the PCBA layer and configured to power on the VSM, where user access of the first printed Ag—AgCl electrode completes a circuit with the second printed Ag—AgCl electrode.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 17, 2021
    Applicant: Jabil Inc.
    Inventors: Yusuf Abu Tayeb Bhagat, Girish Satish Wable, Patrick John Verdon, Michael Nicholas Arfaras, Thong Bui, Krishnaveni Das, Sai Guruva Reddy Avuthu, Arnoldo Reta, Jorg Richstein
  • Patent number: 11026672
    Abstract: Described herein are methods and apparatus for approximating targeted tissue by intertwining two or more sutures together. The sutures are attached to the targeted tissue and routed to a twister device. The twister device secures end portions of the sutures and twists them to intertwine the sutures. Controlling the number of twists provides control over the forces applied to the targeted tissue. In conjunction with visualization feedback, real-time adjustments can be made to achieved targeted results, such as elimination of mitral regurgitation when the disclosed methods and apparatus are applied to mitral valve repair.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: June 8, 2021
    Assignees: Harpoon Medical, Inc., University of Maryland, Baltimore
    Inventors: William Niland, Felino V. Cortez, Jr., James S. Gammie, Michael Nicholas D'ambra, Peter Wilson, Stephen Cournane
  • Publication number: 20210150408
    Abstract: According to one embodiment, a method, computer system, and computer program product for dynamically modifying interactive digital content based on viewer sentiment is provided. The present invention may include measuring, by one or more sensors, characteristics of viewers associated with a viewed portion of the interactive digital content, while the viewers are viewing the interactive digital content; inferring the sentiment of the viewers with respect to the viewed portion of the interactive digital content based on the measured characteristics; predicting content satisfying to the viewers based on the sentiment; and modifying the interactive digital content in real time based on the predicted content.
    Type: Application
    Filed: November 18, 2019
    Publication date: May 20, 2021
    Inventors: Shikhar Kwatra, Adam Lee Griffin, Jennifer L. Szkatulski, Michael Nicholas Virnoche
  • Publication number: 20210139459
    Abstract: 2-Aminopyrimidine-substituted 2H-indazole compounds of formula (I), where R1 is hydrogen, and their prodrugs, where R1 is a metabolizable group under physiological conditions, as cyclin-dependent kinase (CDK) and cell-proliferation inhibitors, and therapeutic uses and methods of preparation thereof, are disclosed. These compounds, and pharmaceutically acceptable salts, solvates, prodrugs, and pharmaceutical compositions thereof, are useful for treating diseases and disorders associated with activity of cyclin-dependent kinases, in particular CDK4/6, including but not limited to various cancers and inflammation-related diseases or conditions.
    Type: Application
    Filed: January 29, 2019
    Publication date: May 13, 2021
    Inventors: Michael Nicholas Greco, Michael John Costanzo, Jirong Peng, Don Zhang
  • Publication number: 20210091995
    Abstract: A method, system, and computer program product for contextual generation of an ephemeral network are provided. The method detects an initiating event for network generation associated with a user of a first computing device. The method determines a duration of the initiating event. A set of network members is determined based on the initiating event and the duration. The method establishes an ephemeral network, connecting at least a portion of computing devices associated with the set of network members. The ephemeral network is terminated in response to detecting a completion event. In response to terminating the ephemeral network, member information for the set of network members is removed from the portion of the computing devices.
    Type: Application
    Filed: September 23, 2019
    Publication date: March 25, 2021
    Inventors: Craig M. Trim, Shikhar Kwatra, Jennifer SZKATULSKI, Adam Lee Griffin, Michael Nicholas Virnoche
  • Publication number: 20200407855
    Abstract: Implementations provide cold spray additive manufacturing (“CSAM”) with gas recovery in situ in an open environment without requiring part disassembly and removal to a repair facility. Recapturing and reusing gas in an open environment reduces costs, rendering CSAM more commercially viable and efficient, and avoids risk of new damage to parts from contemporary pre-existing CSAM processes. A gas recovery nozzle attaches to a supersonic nozzle and sends used gas to a gas recovery sub-system by capturing gas that is deflected on impact with the part during CSAM. Captured gas is stored for reuse. A flexible coupling controls distance from the gas recovery nozzle to a part substrate to prevent (1) nozzle clogging; (2) stationary shock wave interference with gas flow; and (3) gas flow misdirection. The gas recovery nozzle also suppresses disruptive supersonic sounds. Implementations enable capture for later reuse of supersonically-propelled gas during in-situ CSAM in open environments.
    Type: Application
    Filed: August 30, 2019
    Publication date: December 31, 2020
    Inventors: Michael Nicholas, Bruno Zamorano Senderos, Kenneth Young
  • Patent number: 10876780
    Abstract: Cooler beverage inserts may include an insert container having an insertion surface and a container retrieval surface opposite the insertion surface. A container interior may extend between the insertion surface and the container retrieval surface. The container interior may be configured to contain a cooling medium. At least one receptacle interior may extend from the insertion surface through the container interior to the container retrieval surface and open to the insertion surface and the container retrieval surface. The at least one receptacle interior may be sized and configured to accommodate a plurality of beverage containers. The at least one receptacle interior may have a uniform width or diameter from the insertion surface to the container retrieval surface. Accordingly, the plurality of beverage containers may be sequentially removable from the at least one receptacle interior without removal of the insert container from the cooler.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: December 29, 2020
    Inventors: Michael Nicholas Tarantino, Ashley Laine Tarantino
  • Publication number: 20200397579
    Abstract: Described herein are devices and methods for mitral valve repair. The devices and methods implant a plurality of distal anchors at an annulus of the mitral valve (e.g., the posterior annulus) and tension artificial chordae to pull the portion of the annulus toward an opposite edge and inward into the ventricle. This can effectively reduce the size of the orifice and increase coaptation. The delivery devices can be configured to be actuated to form a distal anchor made of a pre-formed knot. The delivery devices deliver the pre-formed knot in an elongate configuration. Actuation of the delivery device causes the pre-formed knot to transition from the elongate configuration to the deployed configuration by approximating opposite ends of a suture coupled to a coiled configuration to form one or more loops. After formation of the knot, the delivery device can be withdrawn.
    Type: Application
    Filed: September 4, 2020
    Publication date: December 24, 2020
    Inventors: Michael Nicholas D'Ambra, Felino V. Cortez, JR., James S. Gammie, Peter Wilson, Stephen Epstein, Stephen Cournane, Julie Marie Etheridge, Peter Boyd
  • Patent number: 10765515
    Abstract: Described herein are devices and methods for mitral valve repair. The devices and methods implant a plurality of distal anchors at an annulus of the mitral valve (e.g., the posterior annulus) and tension artificial chordae to pull the portion of the annulus toward an opposite edge and inward into the ventricle. This can effectively reduce the size of the orifice and increase coaptation. The anchor points of the artificial chordae can be offset from the apex of the heart to achieve a targeted force vector on the annulus. In addition, some embodiments include distal anchors implanted in the posterior leaflet in addition to those at the posterior annulus. This allows differential tensioning to be applied to provide for greater flexibility in treating various configurations of mitral valves to improve coaptation.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: September 8, 2020
    Assignees: University of Maryland, Baltimore, Harpoon Medical, Inc.
    Inventors: Michael Nicholas D'ambra, Felino V. Cortez, Jr., James S. Gammie, Peter Wilson, Stephen Epstein, Stephen Cournane, Julie Marie Etheridge, Peter Boyd
  • Publication number: 20200216421
    Abstract: This application discloses novel substituted 2-anilinopyrimidine derivatives, and pharmaceutically acceptable salts, solvates, prodrugs, and compositions thereof, which are useful for the treatment or prevention of diseases or medical conditions mediated by epidermal growth factor receptors (EGFRs), including but not limited to a variety of cancers.
    Type: Application
    Filed: March 16, 2020
    Publication date: July 9, 2020
    Applicants: Beta Pharma, Inc., Beta Pharma (Shanghai) Co., Ltd.
    Inventors: Jirong Peng, Michael John Costanzo, Michael Nicholas Greco, Michael Alan Green, Victoria Lynn Wilde, Don Zhang
  • Patent number: 10647105
    Abstract: What is disclosed is an object holder for retaining an object in a direct-to-object print system and a direct-to-object print system configured to use various embodiments of the object holder of the present invention. In one embodiment, the object holder comprises a shuttle mount configured to slideably traverse a support member positioned parallel to a plane formed by at least one printhead configured to eject marking material on to a surface of an object. A plurality of threads, at least partially comprising a flexible synthetic elastomer, are connected to the shuttle mount. The threads are joined together to form an elastic netting which can be manually expanded around the object to retain the object to the shuttle mount while the object is being printed in the direct-to-object print system.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: May 12, 2020
    Assignee: Xerox Corporation
    Inventors: Michael Nicholas Soures, Jonathan Ross Ireland, Bruce H. Smith, Donald E. Thresh, James D. Van Bortel
  • Publication number: 20200131152
    Abstract: A pharmaceutical formulation of N-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide (compound 1), in particular methanesulfonic acid salt thereof, and methods of using the pharmaceutical formulation for the treatment or prevention of diseases or medical conditions mediated through mutated forms of epidermal growth factor receptor (EGFR), such as various cancers, are disclosed.
    Type: Application
    Filed: June 15, 2018
    Publication date: April 30, 2020
    Applicant: Beta Pharma, Inc.
    Inventors: Michael Nicholas Greco, Michael John Costanzo, Michael Alan Green, Jirong Peng, Victoria Lynn Wilde, Don Zhang
  • Publication number: 20200112844
    Abstract: A host computing device receives an advertisement packet via a low-power personal area network and, in response to the advertisement packet, transmits a connection request via the low-power personal area network, pairs via the low-power personal area network and transmits a data message when pairing via the low-power personal area network. The data message instructs a wearable device to pair via a general personal area network.
    Type: Application
    Filed: October 3, 2019
    Publication date: April 9, 2020
    Inventors: Scott Michael Nicholas Greenberg, Jonathan Brubacher, Mark Oliver Slevinsky, Mark P. DiFranco
  • Patent number: 10590111
    Abstract: This application discloses novel substituted 2-anilinopyrimidine derivatives, and pharmaceutically acceptable salts, solvates, prodrugs, and compositions thereof, which are useful for the treatment or prevention of diseases or medical conditions mediated by epidermal growth factor receptors (EGFRs), including but not limited to a variety of cancers.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: March 17, 2020
    Assignee: Beta Pharma, Inc.
    Inventors: Jirong Peng, Michael John Costanzo, Michael Nicholas Greco, Michael Alan Green, Victoria Lynn Wilde, Don Zhang