Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.

Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.

Abstract: A system may include a first compressor, a second compressor, a first heat exchanger and a second heat exchanger. The first compressor has a first inlet and a first outlet. The second compressor is a sumpless compressor and has a second inlet and a second outlet. The second compressor provides working fluid discharged from the second outlet to the first compressor. The first heat exchanger is disposed upstream of the second compressor and provides working fluid to the second compressor. The second heat exchanger is disposed upstream of the first compressor and provides working fluid to the first compressor.

Abstract: The present invention relates to a protein binding to GARP in the presence of TGF-? and uses thereof.

Abstract: The present invention relates to antibodies that specifically bind to the human c-Met receptor protein and that act as strict antagonists of hepatocyte growth factor (HGF)-mediated activation of the c-Met receptor and also inhibit HGF-independent activation of the human c-Met protein.

Abstract: There is described a method and apparatus for monitoring the play at a gaming table. The disclosed embodiment comprises a dealing shoe adapted to output signals when cards are dealt, and an input device operable by means of sensors and/or by the dealer to output signals indicating the occurrence of events during game play such as the arrival and departure of players from the table, the placing of the first bet for each game, and the resolution of the wagers to end the game. Output signals are received and stored in a memory with an associated timestamp, and analysis of the signals and their respective timestamps enables the apparatus to determine the number of players present for each game, and to calculate the number of games played, and the duration of each game.

Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.

Abstract: Systems and methods for purging lubricant from a first compressor to a second compressor are provided. A control module receives a lubricant purge command, shuts the second compressor to an OFF-mode while the first compressor remains in the ON-mode, restricts working fluid from an outlet of the second compressor from flowing into the first compressor and allows compressed working fluid discharged from an outlet of the first compressor to flow into the inlet of the second compressor such that lubricant in the second compressor flows into the first compressor.

Abstract: A refrigeration system includes first and second compressors and an oil separator. The oil separator includes an inlet for receiving refrigerant and oil from the first compressor, a refrigerant outlet, and an oil outlet. The oil separator separates the oil from the refrigerant. A portion of the oil separator below a horizontal plane intersecting the refrigerant outlet collects separated oil and has a volume equal to a first compressor oil supply. The first compressor oil supply is greater than or equal to 100% and less than or equal to 250% of a first compressor initial oil charge. The first compressor receives oil from the oil outlet when an amount of oil in the portion is less than or equal to the first compressor oil supply. The second compressor receives oil from the refrigerant outlet when the amount of oil in the portion is greater than the first compressor oil supply.

Abstract: The present invention includes a composition and method of producing aspirin in situ, the method comprising: identifying a subject in need of aspirin or aspirin-like compounds; and providing the subject with a composition comprising: a source of methyl salicylate, an acetyl donor, and L-Arginine, wherein the composition is effective to produce aspirin-triggered resolvins in the subject without the deleterious effect of the aspirin or aspirin-like compounds in the stomach.

Abstract: The present invention relates to a protein binding to GARP in the presence of TGF-? and uses thereof.

Abstract: Scroll compressor designs are provided to minimize vibration, sound, and noise transmission. The scroll compressor has a bearing housing, and orbiting and non-orbiting scroll members. The non-orbiting scroll member has a radially extending flanged portion with at least one aperture substantially aligned with the axially extending bore. At least one fastener is disposed within the aperture and the bore. A sound isolation member contacts at least one of the non-orbiting scroll member, the fastener, or the bearing housing, to reduce or eliminate noise transmission. The sound isolation member may be formed of a polymeric composite having an acoustic impedance value greater than the surrounding materials. The sound isolation member may be an annular washer, an O-ring, or a biasing member, by way of non-limiting example. In other variations, fluid passages are provided within the fastener and/or bearing housing to facilitate entry of lubricant oil to further dampen sound and noise.

Abstract: The present invention relates to antagonists, particularly antibodies and antigen binding fragments thereof, that bind to the protein galectin-10, particularly human galectin-10. The galectin-10 antagonists disrupt the crystallization of galectin-10 and are therefore useful in methods of preventing and treating diseases and conditions wherein the pathology is linked to the formation/presence of Charcot-Leyden crystals (CLCs).

Abstract: Systems and methods for performing dynamic coefficient of performance calculations for refrigeration systems are provided. A controller calculates a weighted Carnot efficiency of a refrigeration case based on outdoor temperature data, refrigeration case temperature data, a case load of a refrigeration case, and a case defrost status of the refrigeration case. The controller calculates a weighted coefficient of performance based on based on a refrigerant type, the case load of the refrigeration case, the case defrost status of the refrigeration case, and at least one of the of the refrigeration case temperature data and pressure data. The controller calculates a system performance index (SPI) for the refrigeration case based on the weighted Carnot efficiency of the refrigeration case and weighted actual Carnot efficiency. The controller generates, in response to the SPI being below a threshold, an output indicating that the refrigeration case is operating below a threshold efficiency.

Abstract: Systems and methods for guarding a controller area network are disclosed. In one embodiment, a system for guarding a controller area network comprises one or more processors. The one or more processors may be configured to receive a message destined for the controller area network. The one or more processors may further be configured to determine whether the message is legitimate. The one or more processors may further be configured to modify the message, if the message is determined as illegitimate, as an error message.

Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.

Abstract: The present invention relates to a protein binding to GARP in the presence of TGF-ß and uses thereof.