Abstract: A molecular marker associated with immune parameters in yaks and use thereof in breeding are provided. A single nucleotide polymorphism (SNP) molecular marker associated with immune traits in yaks is identified through screening. The SNP molecular marker is located at position 26593056 on chromosome 3 of the yak reference genome version LU_Bosgru_v3.0, and a nucleotide at the position is G or A. The SNP molecular marker is utilized to quantify levels of immunoglobulin A, immunoglobulin G, and immunoglobulin M in a yak individual, providing a novel SNP molecular marker resource for non-diagnostic, marker-assisted selection of immune traits in yaks, thereby providing a basis for breeding yaks with enhanced immune competence.

Abstract: A molecular marker related to immune traits used as marker-assisted selection for yaks and a use thereof are provided. A SNP locus related to immune traits in yaks is located at base 163,688,148 on chromosome 1 of the yak genome assembly LU_Bosgru_v3.0. The method for detecting immune traits in yaks using a SNP locus and a molecular marker based on the locus has the advantages of high accuracy, fast detection speed, low cost, and easy result judgment compared with the traditional detection method. A new SNP molecular marker resource is provided for marker-assisted selection for immune traits in yaks for non-diagnostic purposes.

Abstract: The present application discloses a method of knowledge sharing between dialogue systems, including: receiving, by a first dialogue system, a knowledge sharing request sent by an external dialogue system, wherein the knowledge sharing request comprises at least feature information of a knowledge point to be shared by the external dialogue system; parsing the knowledge sharing request to determine the feature information of the knowledge point to be shared; and adding the feature information of the knowledge point to be shared to a knowledge base of the first dialogue system to form a shared knowledge base. The embodiment of the present application realizes the sharing of knowledge among different dialogue systems by sharing knowledge points among dialogue systems, and meets the cross-domain dialogue needs of users for dialogue robots to the greatest extent while minimizing costs.

Abstract: The present disclosure relates to the technical field of gene engineering, and in particular, to use of miR-22-3p in promoting the differentiation of yak myoblasts. miR-22-3pmimic can significantly promote the expression of miR-22-3p, and can also significantly increase the expression of differentiation marker genes MYF5 and MYOD at the mRNA and protein levels. miR-22-3p inhibitor can significantly inhibit the expression of miR-22-3p, and can significantly promote the expression of MYF5 and MYOD at the mRNA and protein levels. miR-22-3p mimic can significantly promote the formation of myotubes, while miR-22-3p inhibitor can significantly inhibit the formation of myotubes. The above results indicate that miR-22-3p has a promoting effect in the differentiation process of myoblasts.

Abstract: In some embodiments, a radio-frequency system can include a die having a semiconductor substrate and including a radio-frequency circuit and a sensor implemented thereon. The radio-frequency system can further include another die having a semiconductor substrate and including a control circuit for controlling the radio-frequency circuit and a sensor implemented thereon. The control circuit can be configured to receive sensed information from the sensor of the die with the radio-frequency circuit and sensed information from the sensor of the die with the control circuit, and to be capable of adjusting operation of the radio-frequency circuit based on the sensed information from either or both of the sensors. In some embodiments, the radio-frequency system can be implemented as part of a packaged module.

Abstract: In some embodiments, a semiconductor chip can include a substrate, an active wide-bandgap device implemented on the substrate, and a reference wide-bandgap device implemented on the substrate. The reference wide-bandgap device can be configured to provide a response to a condition that also affects the active wide-bandgap device. Such a semiconductor chip can be included in an architecture that allows operation of the active wide-bandgap device based on the response provided by the reference wide-bandgap device.

Abstract: Disclosed is a human-computer dialogue method including determining a set number of jump topics about a target topic, and generating a topic jump map converging to the target topic based on the correlation intensions among the set number of jump topics; after an initial response to a user's dialogue request, selecting from the topic jump map a jump topic to which the user's dialogue request relates as an initial topic for a first round of recommendation; after completing a human-machine dialogue of the initial topic, determining a jump topic to jump according to the jump probability of jumping out of the initial topic to the k jump topics at the downstream level for a next round of recommendation; and gradually guiding from the initial topic to the target topic by step-by-step recommendation. A more fluent and efficient human-machine dialogue based on a clear communication goal can be realized.

Abstract: The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.

Abstract: The present disclosure provides a mixture of sugar apple and rosemary extracts, optionally in combination with prickly ash extract, for use as skin care compositions.

Abstract: Disclosed is a customization platform for service quality evaluation product, comprising an account management module generating a registration interface and a product creation interface for guiding a user to register and log in to customize a service quality evaluation product; an access mode configuration module generating a product access mode configuration interface for guiding user to configure an access mode for the service quality evaluation product; a voice transcription configuration module generating an industry type selection interface for guiding user to select an industry type and a corresponding voice recognition model for pre-training according to the industry type, the pre-trained voice recognition model converting an input audio file to text content; and a semantic analysis configuration module generating an evaluation information configuration interface for guiding user to input the evaluation information to perform service quality scoring according to the text content and the evaluation inf

Abstract: A microelectronic device has a common terminal transistor with two or more channels, and sense transistors in corresponding areas of the channels. The channels and the sense transistors share a common node in a semiconductor substrate. The sense transistors are configured to provide sense currents that are representative of currents through the corresponding channels. The sense transistors are located so that a ratio of the channel currents to the corresponding sense currents is less than a target value of cross-talk. The microelectronic device may be implemented without a compensation circuit which provides a compensation signal used to adjust one or more of the sense currents to reduce cross-talk. A method of forming the microelectronic device, including estimating a potential distribution in the semiconductor substrate containing the common node of the common terminal transistor, and selecting locations for the sense transistors based on the estimated potential distribution, is disclosed.

Abstract: The present disclosure provides a mixture of sugar apple and rosemary extracts, optionally in combination with prickly ash extract, for use as skin care compositions.

Abstract: The present application discloses a voice dialogue processing method and apparatus. The voice dialogue processing method includes: determining a voice semantics corresponding to a user voice to be processed; determining a reply sentence for the voice semantics based on a dialogue management engine, a training sample set of which is constructed from a dialogue business customization file including at least one dialogue flow, and the dialogue flow includes a plurality of dialogue nodes in a set order; and generating a customer service voice for replying to the user voice according to the determined reply sentence.

Abstract: In some examples, an integrated circuit includes a plurality of power modules formed on a substrate, including a first power module located between second and third power modules. The first power module is configured to conduct a load current, and includes a power transistor and first and second sense transistors. The first sense transistor is disposed at a first position between the second power module and a central axis of the first power module, and the second sense transistor is disposed at a second position between the third power module and the central axis. The first sense transistor is configured to conduct a first sense current; and the second sense transistor is configured to conduct a second sense current. The first and second sense transistors are configured to direct the first and second sense currents toward a measurement circuit that is configured to determine a derived sense current indicative of the load current.

Abstract: A phase-locked loop (PLL) performs hitless switching from a first reference clock (ref1) to a second reference clock (ref2) by entering holdover mode (418), and aligning the feedback clock (fbclk) to the second reference clock while in holdover mode. The alignment is performed by adjusting a divisor input (D) for the multi-mode divider (128) that divides the output clock frequency (PLLout) to generate the feedback clock. Other features are also provided.

Abstract: The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.

Abstract: A time-to-digital converter obtains a Start signal to indicate the start of an event, and a Stop signal whose assertion indicates the stop of the event. The Stop signal can be asserted multiple times due to false indications of the event stop. The TDC continuously monitors the Stop signal to generate a separate digital value for the duration from the event's starting time to each assertion of the Stop signal. The digital values can be analyzed to select the true duration of the event. Other features and embodiments are also provided.

Abstract: The present application discloses a method of knowledge sharing between dialogue systems, including: receiving, by a first dialogue system, a knowledge sharing request sent by an external dialogue system, wherein the knowledge sharing request comprises at least feature information of a knowledge point to be shared by the external dialogue system; parsing the knowledge sharing request to determine the feature information of the knowledge point to be shared; and adding the feature information of the knowledge point to be shared to a knowledge base of the first dialogue system to form a shared knowledge base. The embodiment of the present application realizes the sharing of knowledge among different dialogue systems by sharing knowledge points among dialogue systems, and meets the cross-domain dialogue needs of users for dialogue robots to the greatest extent while minimizing costs.

Abstract: A microelectronic device has a common terminal transistor with two or more channels, and sense transistors in corresponding areas of the channels. The channels and the sense transistors share a common node in a semiconductor substrate. The sense transistors are configured to provide sense currents that are representative of currents through the corresponding channels. The sense transistors are located so that a ratio of the channel currents to the corresponding sense currents is less than a target value of cross-talk. The microelectronic device may be implemented without a compensation circuit which provides a compensation signal used to adjust one or more of the sense currents to reduce cross-talk. A method of forming the microelectronic device, including estimating a potential distribution in the semiconductor substrate containing the common node of the common terminal transistor, and selecting locations for the sense transistors based on the estimated potential distribution, is disclosed.

Abstract: In some examples, an integrated circuit includes a plurality of power modules formed on a substrate, including a first power module located between second and third power modules. The first power module is configured to conduct a load current, and includes a power transistor and first and second sense transistors. The first sense transistor is disposed at a first position between the second power module and a central axis of the first power module, and the second sense transistor is disposed at a second position between the third power module and the central axis. The first sense transistor is configured to conduct a first sense current; and the second sense transistor is configured to conduct a second sense current. The first and second sense transistors are configured to direct the first and second sense currents toward a measurement circuit that is configured to determine a derived sense current indicative of the load current.