Patents by Inventor Min Shen

Min Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9682983
    Abstract: The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds may also be used to reduce circulating levels of ApoB-100 or LDL and treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: June 20, 2017
    Assignees: The Brigham and Women's Hospital, Inc., Dept. of Health and Human Services, National Institutes of Health
    Inventors: Asaf Alimardanov, Gregory D. Cuny, Gurmit Singh Grewal, Arthur Lee, John C. McKew, Agustin H. Mohedas, Min Shen, Xin Xu, Paul B. Yu
  • Patent number: 9653545
    Abstract: A MOSFET disposed between shallow trench isolation (STI) structures includes an epitaxial silicon layer formed over a substrate surface and extending over inwardly extending ledges of the STI structures. The gate width of the MOSFET is therefore the width of the epitaxial silicon layer and greater than the width of the original substrate surface between the STI structures. The epitaxial silicon layer is formed over the previously doped channel and is undoped upon deposition. A thermal activation operation may be used to drive dopant impurities into the transistor channel region occupied by the epitaxial silicon layer but the dopant concentration at the channel location where the epitaxial silicon layer intersects with the gate dielectric, is minimized.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: May 16, 2017
    Assignee: Taiwan Semiconductor Manufacturing Co., Ltd.
    Inventors: Mahaveer Sathaiya Dhanyakumar, Wei-Hao Wu, Tsung-Hsing Yu, Chia-Wen Liu, Tzer-Min Shen, Ken-Ichi Goto, Zhiqiang Wu
  • Publication number: 20170124777
    Abstract: A method and apparatus are provided for autonomously detecting and reporting anomalies in actions of an autonomous mobile node, or in behaviors of a swarm of autonomous mobile nodes to an operator. The autonomous mobile node may experience anomalies or unexpected situations due to various failures or external influence (e.g. natural weather phenomena, enemy threats). During a training phase a prediction model and a structured model may be established from measurement data received from one or more sensors of an autonomous mobile node or a swarm of nodes while executing an action or behavior under normal circumstances. A prediction model forecasts the expected outcome of an action or behavior, and structured model helps quantify the similarity of a learned action or behavior to the currently observed situation. Based on the measurement data applicable models can be used for an action or behavior for anomaly detection in the action or behavior.
    Type: Application
    Filed: December 29, 2016
    Publication date: May 4, 2017
    Applicant: EpiSys Science, Inc.
    Inventors: Nadeesha Oliver RANASINGHE, Bong Kyun RYU, Wei-Min SHEN
  • Publication number: 20170035760
    Abstract: Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).
    Type: Application
    Filed: August 11, 2016
    Publication date: February 9, 2017
    Inventors: Matthew B. Boxer, Martin J. Walsh, Li Liu, Cordelle D. Tanega, Min Shen, Kent Lai, Manshu Tang, Douglas S. Auld
  • Publication number: 20170039086
    Abstract: A system, method, and apparatus are provided for determining an appropriate time to disrupt operation of a computer system, subsystem, or component, such as by shutting it down or taking it offline. Historical measurements of work accumulated on the component at different times are used to generate one or more forecasts regarding future amounts of work that will accumulate at different times. Accumulated work may include all job/tasks (or other executable objects) that have been initiated but not yet completed at the time the measurement is taken, and may be expressed in terms of execution time and/or component resources (e.g., cpu, memory). When a request is received to disrupt component operations, based on an urgency of the disruption a corresponding accumulated work threshold is chosen to represent the maximum amount of accumulated work that can be in process and still allow the disruption, and the disruption is scheduled accordingly.
    Type: Application
    Filed: August 3, 2015
    Publication date: February 9, 2017
    Applicant: LinkedIn Corporation
    Inventors: Zhenyun Zhuang, Min Shen, Haricharan K. Ramachandra, Cuong H. Tran, Suja Viswesan, Badrinath K. Sridharan
  • Patent number: 9532989
    Abstract: The present invention relates to compounds of Formula P-I where the variables (e.g. R1, Y, A, R1, Ra, Ra?, Rb, Rb?, Rc, Rc?, Rd, Rd?, Re, or Re?) and compositions useful for inhibiting and/or reducing platelet deposition, adhesion and/or aggregation. The present invention further relates to methods for the treatment or prophylaxis of thrombotic disorders, including stroke, myocardial infarction, unstable angina, peripheral vascular disease, abrupt closure following angioplasty or stent placement and thrombosis as a result of vascular surgery.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: January 3, 2017
    Assignees: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, THE ROCKEFELLER UNIVERSITY
    Inventors: Barry S. Coller, Craig Thomas, Marta Filizola, Joshua McCoy, Wenwei Huang, Min Shen
  • Patent number: 9537954
    Abstract: A method and apparatus are provided for autonomously detecting and reporting anomalies in actions of an autonomous mobile node, or in behaviors of a swarm of autonomous mobile nodes to an operator. The autonomous mobile node may experience anomalies or unexpected situations due to various failures or external influence (e.g. natural weather phenomena, enemy threats). During a training phase a prediction model and a structured model may be established from measurement data received from one or more sensors of an autonomous mobile node or a swarm of nodes while executing an action or behavior under normal circumstances. A prediction model forecasts the expected outcome of an action or behavior, and structured model helps quantify the similarity of a learned action or behavior to the currently observed situation. Based on the measurement data applicable models can be used for an action or behavior for anomaly detection in the action or behavior.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: January 3, 2017
    Assignee: EpiSys Science, Inc.
    Inventors: Nadeesha Oliver Ranasinghe, Bong Kyun Ryu, Wei-Min Shen
  • Publication number: 20160365447
    Abstract: The demand for increased performance and shrinking geometry from ICs has brought the introduction of multi-gate devices including finFET devices. Inducing a higher tensile strain/stress in a region provides for enhanced electron mobility, which may improve performance. High temperature processes during device fabrication tend to relax the stress on these strain inducing layers. The present disclosure relates to a method of forming a strain inducing layer or cap layer at the RPG (replacement poly silicon gate) stage of a finFET device formation process. In some embodiments, the strain inducing layer is doped to reduce the external resistance.
    Type: Application
    Filed: August 25, 2016
    Publication date: December 15, 2016
    Inventors: Zhiqiang Wu, Yi-Ming Sheu, Tzer-Min Shen, Chun-Fu Cheng, Hong-Shen Chen
  • Patent number: 9499377
    Abstract: An adjustable hydraulic jack with a slider locking structure that includes a chassis, hydraulic assembly, boom assembly, and handle lever. The boom assembly includes a bracket, a fore arm, and a rear arm. The bracket includes a pull handle, left and right bracket side-plates, and a bracket-fixing pin. The bracket is connected to one end of the fore arm, the other end of the fore arm is connected to one end of the rear arm, and the other end of the rear arm is connected to the chassis. The left and right bracket side-plates have left and right side-plate sockets on their respective bottoms; the fore arm has left and right sliding chutes and a spring-loaded fixing pin fixed on its upper end. A slider locking device is arranged between the bracket and the fore arm, and includes left and right sliders, a spring and at least one pin shaft.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: November 22, 2016
    Assignee: CHANGSHU TONGRUN AUTO ACCESSORY CO., LTD.
    Inventors: Min Shen, Xiaoming Shi
  • Patent number: 9490801
    Abstract: A rapid cutoff device includes a thyristor AC switch for supplying an AC current from a first AC circuit to a second AC circuit. A serially-connected circuit of a first switch and a first capacitor parallel-connects with the first AC circuit. A serially-connected circuit of a second switch and a second capacitor parallel-connects with the second AC circuit. When cutting off the thyristor AC switch, the first switch is operated to conduct the first capacitor in a first direction for the AC current charging to the first capacitor, alternatively, the second switch is operated to conduct the second capacitor in a second direction for the AC current charging to the second capacitor, thereby lowering a current in the thyristor AC switch approaching a zero value and thus rapidly cutting off it.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: November 8, 2016
    Assignee: Ablerex Electronics Co., Ltd.
    Inventors: Jia-Min Shen, Yi-Hao Chang, Chia-Hung Lee
  • Patent number: 9461581
    Abstract: A shadowing compensation device for a solar cell module has an input port, an isolated DC-DC power converter, and an output port. The input port is connected to two output ends of a solar cell array including multiple solar cell modules connected in series. The output port is connected to one of the multiple solar cell modules of the solar cell array. When one of the solar cell modules connected to the output port of shadowing compensation device has been shaded, the isolated DC-DC power converter outputs a compensating current to the solar cell module that has been shaded for increasing the output voltage of the solar cell module that has been shaded, and increasing the output voltage and output power of the solar cell array.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: October 4, 2016
    Assignee: Ablerex Electronics Co., Ltd.
    Inventors: Ya-Tsung Feng, Jia-Min Shen, Wen-Jie Hou
  • Patent number: 9455346
    Abstract: The demand for increased performance and shrinking geometry from ICs has brought the introduction of multi-gate devices including finFET devices. Inducing a higher tensile strain/stress in a region provides for enhanced electron mobility, which may improve performance. High temperature processes during device fabrication tend to relax the stress on these strain inducing layers. The present disclosure relates to a method of forming a strain inducing layer or cap layer at the RPG (replacement poly silicon gate) stage of a finFET device formation process. In some embodiments, the strain inducing layer is doped to reduce the external resistance.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: September 27, 2016
    Assignee: Taiwan Semiconductor Manufacturing Co., Ltd.
    Inventors: Zhiqiang Wu, Yi-Ming Sheu, Tzer-Min Shen, Chun-Fu Cheng, Hong-Shen Chen
  • Patent number: 9447087
    Abstract: Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: September 20, 2016
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Matthew B. Boxer, Martin J. Walsh, Li Liu, Cordelle D. Tanega, Min Shen, Kent Lai, Manshu Tang, Douglas S. Auld
  • Publication number: 20160255571
    Abstract: A method and apparatus for managing access network information are provided. The method includes: the dynamic access network information is obtained, and the current access network information list can be updated in real time according to the obtained dynamic access network information, so as to ensure that access network information obtained by a user terminal from the access network information list is latest information updated in real time. Thus, after the user terminal obtains the information, a process of scanning an access network to determine current availability information of the network can be omitted, so that the switching delay can be reduced, the switching efficiency can be improved, and the power consumption of the user terminal can be reduced, thereby improving the satisfaction degree of user experience.
    Type: Application
    Filed: April 25, 2014
    Publication date: September 1, 2016
    Inventors: Wei YAN, Min SHEN, Na ZHOU, Yuzhen HUO
  • Publication number: 20160212597
    Abstract: Provided are a method for optimizing the multicast group and an anchor. A set of nodes requesting for the same multicast group data and sharing the same Access Gateway (AG) is identified in a multicast group, and the same multicast group data is transmitted to each node in the set of nodes via the same AG thereby forwarding multicast data to different nodes via the same gateway, saving traffic of a network side, and optimizing the multicast group. In addition, the node optimization method allows the anchor to optimize multicast routing of the nodes requesting for the same multicast group data and sharing the same AG to the same shared gateway for forwarding if a node has a plurality of access interfaces in the present application.
    Type: Application
    Filed: June 11, 2014
    Publication date: July 21, 2016
    Inventors: Yong CUI, Yan LIU, Xin XU, Wendong WANG, Guoyan LIU, Min SHEN, Na ZHOU, Chunhui ZHU
  • Patent number: 9344082
    Abstract: A rapid cutoff device includes a thyristor DC switch, a switch and a capacitor. An operation method includes: connecting the thyristor DC switch between a first DC circuit and a second DC circuit; serially connecting the switch and the capacitor which further parallel connects the first DC circuit; when the thyristor DC switch is conducted, supplying a DC current via the thyristor DC switch; when a drive signal of the thyristor DC switch stops, operating the switch to conduct the capacitor which is charged by the first DC circuit to rapidly lower a current of the thyristor DC switch approaching a zero value, thereby rapidly cutting of the thyristor DC switch.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: May 17, 2016
    Assignee: Ablerex Electronics Co., Ltd.
    Inventors: Jia-Min Shen, Yi-Hao Chang, Chia-Hung Lee
  • Patent number: 9303044
    Abstract: The present invention relates to compounds and compositions of Formula P useful for inhibiting and/or reducing platelet deposition, adhesion and/or aggregation. The definitions of variables A, B, R2, R3, R4, Ra, Ra?, Rb, Rb?, Rc, Rd, Rd?, Re, and Re? are provided in the disclosure. The present invention further relates to methods for the treatment or prophylaxis of thrombotic disorders, including stroke, myocardial infarction, unstable angina, peripheral vascular disease, abrupt closure following angioplasty or stent placement and thrombosis as a result of vascular surgery.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: April 5, 2016
    Assignees: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE ROCKEFELLER UNIVERSITY, ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Barry S. Coller, Craig Thomas, Marta Filizola, Joshua McCoy, Wenwei Huang, Min Shen, Jian-Kang Jiang
  • Publication number: 20160065209
    Abstract: A rapid cutoff device includes a thyristor AC switch for supplying an AC current from a first AC circuit to a second AC circuit. A serially-connected circuit of a first switch and a first capacitor parallel-connects with the first AC circuit. A serially-connected circuit of a second switch and a second capacitor parallel-connects with the second AC circuit. When cutting off the thyristor AC switch, the first switch is operated to conduct the first capacitor in a first direction for the AC current charging to the first capacitor, alternatively, the second switch is operated to conduct the second capacitor in a second direction for the AC current charging to the second capacitor, thereby lowering a current in the thyristor AC switch approaching a zero value and thus rapidly cutting off it.
    Type: Application
    Filed: December 31, 2014
    Publication date: March 3, 2016
    Inventors: Jia-Min Shen, Yi-Hao Chang, Chia-Hung Lee
  • Patent number: D784026
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: April 18, 2017
    Inventor: Min Shen
  • Patent number: D790224
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: June 27, 2017
    Inventor: Min Shen