Abstract: The present application relates to isolated proteins, particularly monoclonal antibodies, in particular CDR-grafted, humanized antibodies which bind to RAGE protein. Specifically, these antibodies have the ability to inhibit the binding of RAGE to its various ligands. The antibodies or portions thereof of described in the present application are useful for treating a disease or disorder characterized by or induced by pathophysiological ligands of RAGE, for example misfolded proteins like amyloid ? and advanced glycation-end-products.

Abstract: Scheduling of threads in a multi-core system running various legacy applications along with multi-core compatible applications is configured such that threads from older single thread applications are assigned fixed affinity. Threads from multi-thread/single core applications are scheduled such that one thread at a time is made available to the cores based on the thread priority preventing conflicts and increasing resource efficiency. Threads from multi-core compatible applications are handled regularly.

Abstract: The invention provides an isolated, dual-specific antibody, or an antigen-binding portion thereof, which is specific for human IL-1? and human IL-1?. The dual specific antibodies of the invention also neutralize both human IL-1? and human IL-1?. The invention also provides domain antibodies (dAbs) specific for human IL-1? and human IL-1?.

Abstract: A facsimile machine includes a receiving unit, a processing unit and a sending unit. The receiving unit receives facsimile data from a facsimile sending machine over a telephone network. The processing unit extracts a source identification number from the facsimile data and determines whether the source identification number matches one of a plurality of predetermined identification numbers. If the source identification number matches one of the predetermined identification numbers, the sending unit sends the facsimile data to a destination facsimile machine associated with a destination facsimile number over the telephone network.

Abstract: A depth map generating device. A first depth information extractor extracts a first depth information from a main two dimensional (2D) image according to a first algorithm and generates a first depth map corresponding to the main 2D image. A second depth information extractor extracts a second depth information from a sub 2D image according to a second algorithm and generates a second depth map corresponding to the sub 2D image. A mixer mixes the first depth map and the second depth map according to adjustable weighting factors to generate a mixed depth map. The mixed depth map is utilized for converting the main 2D image to a set of three dimensional (3D) images.

Abstract: The present invention describes IL-1? binding proteins, including chimeric, CDR-grafted, and humanized antibodies that bind IL-1?. Binding proteins of the invention have high affinity for IL-1? and neutralize IL-1? activity. A binding protein of the invention can be a full-length antibody or an IL-1?-binding portion thereof. Methods of making and methods of using the binding proteins of the invention are also described. The IL-1? binding proteins of the invention are useful for detecting IL-1? and for inhibiting IL-1? activity, including in a human subject suffering from a disease or disorder in which IL-1? activity is detrimental.

Abstract: A hybrid transmission includes torque machines and an energy storage device connected thereto. Thee hybrid transmission is operative to transfer power between an input member and an output member and the torque machines. A method for controlling the hybrid transmission includes monitoring operating parameters of the hybrid transmission, monitoring an operator demand for power, determining an output torque range to the output member based upon states of the operating parameters of the hybrid transmission, constraining the output torque range to the output member based upon the operator demand for power, and determining input torque constraints to the input member based upon the constrained output torque range to the output member.

Abstract: A hybrid transmission is operative to transfer torque between an input member and torque machines and an output member in one of a plurality of fixed gear and continuously variable operating range states through selective application of torque transfer clutches. The torque machines are operative to transfer power from an energy storage device. A method for controlling the hybrid transmission includes operating the hybrid transmission in one of the operating range states, determining a first set of internal system constraints on output torque transferred to the output member, determining a second set of internal system constraints on the output torque transferred to the output member, and determining an allowable output torque range that is achievable within the first set of internal system constraints and the second set of internal system constraints on the output torque transferred to the output member.

Abstract: The invention provides an apparatus for regulating the temperature of a chemical and/or biological sample and a method of using the same. The apparatus includes at least one temperature control module. The temperature control module includes a heater, a conductor of caloric, and a temperature sensor. The heater of the temperature control module is adapted to thermally communicate with a removable substrate, on which said chemical and/or biological sample is placed, via the conductor of caloric. The temperature sensor of the temperature control module is adapted to detect and control the temperature of the substrate via the conductor of caloric. The apparatus is designed such that the substrate is situated above said temperature control module to entirely cover said temperature control module.

Abstract: A remote power group distribution control system has a host computer, at least one network server and multiple power distribution units (PDUs) connected to the host computer through the at least one network server. The host computer has a power distribution control module. Each PDU is connected with multiple power consuming equipment having identical or similar characteristics to supply an operating power and an uninterruptible power. When the power distribution control module is executed, the host computer searches the PDUs connected thereto through the at least one network server, displays all power-consuming equipment connected to each PDU, generates a group management window to assign each power-consuming equipment to a group, and remotely controls the power consuming equipment on a group basis. Accordingly, the present invention addresses a solution conveniently powering on or off remote power-consuming equipment pertaining to a group.

Abstract: An apparatus for capturing the image of a wet/moist fingerprint. The apparatus includes: a prism having an imaging plane on which a finger having valleys and ridges is place, a bottom plane parallel to the imaging plane and a reflective plane intercepting the imaging plane and intercepting the bottom plane at an angle ?; a light source for generating a light with an incident angle of approximately 0° with respect to a surface normal of the imaging plane; and a lens for capturing light reflected from the reflective plane. The apparatus further includes an image sensor for generating an image of the valleys and ridges of the finger, wherein the reflective plane is arranged in such a way to meet the equation of ?>45 +(arc sin (n1/n2))/2, where n1 is a refraction index of medium filled between the valleys of the finger and the imaging plane, and n2 is refraction index of the prism.

Abstract: A LGP plate-to-plate manufacturing includes the steps of: preparing an optical substrate with a first surface and a second surface; mechanically extruding a first integrated microstructure on the first surface of the optical substrate; coating an optical layer on the first or second surface of the optical substrate; and curing the optical layer to directly form a second microstructure on the first or second surface of the optical substrate; wherein the first integrated microstructure and the second microstructure are separately formed at a time to provide a light guide plate structure. In an embodiment, an additional optical layer is provided on the optical substrate.

Abstract: A LGF roll-to-roll manufacturing includes the steps of: preparing a first optical layer with a first surface and a second surface; mechanically extruding a first integrated microstructure on the first surface of the first optical layer; subsequently coating a second optical layer on the first or second surface of the first optical layer; and curing the second optical layer to directly form a second microstructure on the first or second surface of the first optical layer; wherein the first integrated microstructure and the second microstructure are separately formed at a time to provide a light guide film structure. In an embodiment, an additional optical layer is provided on the first optical layer.

Abstract: The present invention features nucleic acids for recombinant protein expression in mammalian cell culture. The episomal vectors of the invention promote high protein production in mammalian cells expressing the SV40 T Ag or Epstein-Barr virus nuclear antigen (e.g., COS7 or HEK293-6E cells). The methods and systems are useful, for example, in pharmaceutical drug development and cloning, especially for the production of antibodies.

Abstract: A system for focusing a light beam may be used for multi-photon stereolithography. It comprises a collimator or expander for adjusting the beam divergence and a scanner for directing the beam onto a focusing device to focus the beam to a focal point or beam waist and to scan the focused beam. A controller controls adjustment of the beam divergence so that the focal point or beam waist is scanned substantially in a plane. A light source may be provided to generate the light beam. The expander may comprise a diverging lens and a converging lens for expanding the beam to produce a collimated beam. The divergence of the collimated beam is dependent on the distance between the diverging lens and the converging lens, which may be adjusted to adjust the beam divergence. The focusing device may comprise a dry objective lens to focus the collimated beam onto the target material to induce multi-photon absorption in the target material at the beam waist of the focused beam.

Abstract: TNF-? binding proteins, including chimeric, CDR-grafted, and humanized antibodies that bind TNF-? are provided. Binding proteins have high affinity for TNF-? and neutralize TNF-? activity. A binding protein can be a full-length antibody or a TNF-?-binding portion thereof. Methods of making and methods of using the binding proteins are also described. The TNF-? binding proteins are useful for detecting TNF-? and for inhibiting TNF-? activity, including in a human subject suffering from a disease or disorder in which TNF-? activity is detrimental.

Abstract: A liquid crystal display device and a method for driving the same are disclosed. The liquid crystal display device includes a liquid crystal panel and a driving circuit. The driving circuit includes a timing controller, a detection unit, a level shift circuit, a gate driver unit, and at least one source driver unit. The timing controller receives a frame rate and provides at least one gate turn-on signal and a source data writing signal for each of at least two different frame rates. The detecting unit detects the frame rate. The timing controller adjusts a duty cycle of the source data writing signal, so that the charge time is maintained to be substantially constant for any one of the different frame rates. Accordingly, a problem of flickering phenomenon can be avoided.

Abstract: In one embodiment, the present invention is a system for organizing data flow for two dimensional digital image processing. The system includes a memory access module for accessing an external memory containing image data to be processed, and a data flow organizer module for preparing a data stream from the input image data accessed by the memory access module. The data flow organizer module predicts future data needed for processing, and the memory access module pre-fetches the predicted data from the memory. A data processing module processes the pre-fetched data from the data flow organizer module. Address generation for accessing the memory is performed independent and in parallel with processing the pre-fetched data.

Abstract: A hybrid transmission is operative to transfer power between an input member and first and second torque machines and an output member in a fixed gear operating range state. The first and second torque machines are connected to an energy storage device.