Abstract: The present invention provides a series of polypeptides containing a modified structure. The series of polypeptides act on three targets, i.e., GLP-1, GIP and GCG, and has prospects of being developed into drugs for the prevention or treatment of metabolic diseases, wherein the sequence of the polypeptides is as shown in formula Z-3.

Abstract: A leg of a power converter includes: a first one of (a) a first power module and (b) a first die, the first one including a high side switch having a first terminal configured to be connected to a first direct current (DC) busbar having a first potential; and a second one of (a) a second power module and (b) a second die, the second one including a low side switch having a first terminal configured to be connected to a second DC busbar having a second potential that is different than the first potential; and an alternating current (AC) busbar disposed vertically (a) between the first one and the second one and (b) between the first DC busbar and the second DC busbar.

Abstract: An automatic cleaning device, including: a moving platform, which is configured to move on an operating surface; and a cleaning module which is assembled on the moving platform and is configured to clean the operating surface. The cleaning module includes: a first rolling brush, which is arranged in a first direction perpendicular to the front-rear axis of the moving platform, the first rolling brush including a first filler, and the first filler being arranged in an axial direction of the first rolling brush; and a second rolling brush which is arranged in a direction parallel to the first rolling brush, the second rolling brush including a second filler, and the second filler being arranged in an axial direction of the second rolling brush, wherein the modulus of elasticity of the first filler is less than the modulus of elasticity of the second filler.

Abstract: Laundry machines and methods for operating the same are disclosed. A laundry machine includes a container for containing laundry and a dehumidifier including a circulation fan for generating moist air flowing out of the container toward a moisture absorption and removal structure for absorbing moisture in the moist air, a regeneration fan for generating airflow including the moisture absorbed by the moisture absorption and removal structure to flow toward a condenser for condensing water from the generated airflow. The moisture absorption and removal structure is disposed adjacent to the circulation fan, the regeneration fan, and the condenser; wherein the moisture absorption and removal structure comprises a roller assembly, a functional roller is provided on at least one of a bottom portion of the roller assembly or a side of the roller assembly.

Abstract: A spintronic device, an array, and a method for optimizing a recursive neural network are provided. The spintronic device includes: a magnetic domain device with a preset thickness, wherein the magnetic domain device is configured to form a labyrinth-like magnetic domain structure under a modulation of a Dzyaloshinskii-Moriya interaction and a dipole interaction, the labyrinth-like magnetic domain structure includes a plurality of magnetic domain regions with random magnetic domain directions, and a boundary between adjacent two magnetic domain regions is a magnetic domain wall; a heterogenous thin film of at least one cycle, wherein the heterogenous thin film is disposed on a first surface of the magnetic domain device; at least four electrodes disposed on a second surface of the magnetic domain device, wherein the four electrodes are respectively connected to different magnetic domain regions.

Abstract: A cleaning module includes: a first rolling brush including a first brush member, the first brush member including first brushes configured to be rotatable in a first rotational direction to form a first brush outer end trajectory; and a second rolling brush arranged substantially side by side with the first rolling brush and including a second brush member, the second brush member including second brushes configured to be rotatable in a second rotational direction to form a second brush outer end trajectory, wherein the first brush outer end trajectory and the second brush outer end trajectory form an interfering region, and a distance between at least one of the first brushes and at least one of the second brushes is greater than zero when the at least one of the first brushes and the at least one of the second brushes rotate into the interfering region.

Abstract: Methods for forming boron nitride layer on a surface of a substrate by a plasma enhanced atomic layer deposition (PEALD) process are provided. The methods comprise the steps of providing a substrate withing a reaction chamber; and executing at least one deposition cycle. The deposition cycle comprises providing a boron precursor into the reaction chamber, the boron precursor comprising boron halide; and providing a reactive species generated from a plasma produced from a reactant gas into the reaction chamber.

Abstract: A control method includes obtaining a current state of an air conditioner, determining a current comfort level based on the current state, constructing one or more potential state combinations based on the current state, determining, based on the one or more potential state combinations, one or more comfort levels each corresponding to one of one or more potential states in the one or more potential state combinations, determining a target state based on the current comfort level and the one or more comfort levels, and controlling the air conditioner to operate according to an operating parameter corresponding to the target state.

Abstract: Provided are salts of a compound of formula (I) having an ATX inhibitory activity. The salts comprises inorganic acid salts or organic acid salts, and solid forms of the salts, such as crystal forms. The salts of the compound of formula (I) and their crystal forms according to the present disclosure have a good solubility, stability and hygroscopicity, and are more suitable for medicinal use. Moreover, their preparation methods are simple and convenient, and are suitable for large-scale production.

Abstract: A motor control method includes: acquiring a first rotational speed error of a rotor of a motor corresponding to a current moment; acquiring a speed compensation value for the rotor according to a preset speed drop graph, which represents a graphical representation of speed versus time when a rotational speed of the rotor drops; calculating an electric current compensation value according to the speed compensation value and a preset speed-current mapping model; acquiring an electric current reference value corresponding to the current moment, which is an electric current value for controlling the rotational speed of the rotor; and controlling the motor according to the electric current compensation value if the first rotational speed error is greater than a preset error, or controlling the motor according to the electric current reference value if the first rotational speed error is less than or equal to the preset error.

Abstract: Isolated antibodies or antigen-binding fragments against Claudin-6 (CLDN6) include: chimeric monoclonal antibodies and humanized monoclonal antibodies. This application also provides conjugates, multispecific antibodies, chimeric antigen receptors, pharmaceutical compositions and kits which include the isolated anti-CLDN6 antibodies or the antigen-binding fragments. The disclosed antibodies or the antigen-binding fragments can be used for diagnosing cancer and/or determining whether cancer cells express CLDN6, as well as for treating and/or preventing various cancers or diseases associated with cells expressing CLDN6 in subjects.

Abstract: An ion-electron mixed conductor ceramic comprises Ag-modified LLZTO ceramic; a preparation method of the ion-electron mixed conductor ceramic includes the following steps: adding LLZTO ceramic into a solution containing a soluble silver salt and a reducing agent to obtain silver oxide, and reacting the silver oxide under the action of the reducing agent to prepare the Ag-modified LLZTO ceramic; a composite solid electrolyte comprises the aforementioned ion-electron mixed conductor ceramic, a lithium salt and a polymer; a battery electrode material comprises the aforementioned ion-electron mixed conductor ceramic; a battery comprises the aforementioned ion-electron mixed conductor ceramic or the aforementioned solid electrolyte; when the modified ceramic is applied in electrode materials, it can simultaneously play a role in transporting electrons and ions, improve electrode kinetics, and has good application prospects in the battery field.

Abstract: This application discloses a blockchain-based data processing method performed by a computer device. The method includes: in response to a selection operation of media elements associated with a target object, acquiring a target media element combination based on the selected media elements; in response to a virtual resource creation operation for the target media element combination, generating target combined media data corresponding to the target media element combination; and transmitting a virtual resource creation request for the target combined media data to a blockchain network, wherein the blockchain network creates a target on-chain virtual resource corresponding to the target combined media data after determining that the target combined media data passes duplicate check and verification, and an ownership right of the target on-chain virtual resource belonging to the target object.

Abstract: An aerosol generating substrate, an aerosol generating article, and an electronic atomizing device are provided. The aerosol generating substrate includes a base part and a plurality of subparts, the plurality of subparts are located at an outer side of the base part in a first direction, the plurality of subparts are spaced apart from each other in a second direction of the base part, and a space between any two adjacent subparts of the plurality of subparts is a gap space, in which the first direction and the second direction intersect with each other.

Abstract: This invention relates to genetically improved Eastern oyster (Crassostrea virginica) lines developed by the Morgan State University Patuxent Environmental and Aquatic Research Laboratory. Derived from Maryland wild populations, these diploid, triploid, and tetraploid lines exhibit enhanced tolerance to low salinity, rapid growth, and disease resistance. Genetic improvement was achieved through multiple approaches including phenotype-based, genomic, and marker-assisted selection. Several diploid low-salinity-tolerant lines (LS2019, LS2025, LS H-GEBV) and a fast-growing line (FG H-GEBV) have been produced and are undergoing field evaluation, while MSX-resistant lines are under development through field challenge testing. Multi-trait genomic selection enables integration of growth, salinity tolerance, and disease resistance into single lines based on trait correlations and production needs.

Abstract: A method and system for image acquisition may be provided. A first exposure duration of a first image sensor and a second exposure duration of each of at least one second image sensor may be obtained. For each second image sensor, a synchronization time difference between the first image sensor and the second image sensor may be determined based on an exposure duration difference between the first exposure duration and the second exposure duration of the second image sensor, and first image data and second image data from the first image sensor and the second image sensor may be acquired by sending synchronizing signals to the first image sensor and the second image sensor based on the synchronization time difference. A target image of the target scene may be generated based on the first image data and the second image data of each second image sensor.

Abstract: This invention relates to the development of heat-tolerant soft-shell clam (Mya arenaria) lines for aquaculture through selective breeding and molecular genetic approaches. Two methods are employed: (1) phenotype-based selection, in which clams are exposed to natural or controlled heat shock conditions (30-33° C.) and survivors are selected across successive generations and multiple populations; and (2) marker-assisted selection (MAS), utilizing single nucleotide polymorphisms (SNPs) identified through genome-wide association studies (GWAS) to select broodstock capable of producing heat-tolerant offspring. The resulting lines exhibit enhanced survival and endurance under elevated temperatures, particularly above the species' critical threshold of 28° C. These heat-tolerant clams enable sustainable aquaculture production in Maryland and other warm, low-salinity estuaries where soft-shell clams historically failed to survive summer heat.

Abstract: An extrusion mold for fabricating an aerosol-generating article is provided. The extrusion mold includes a first form cavity and a plurality of first forming columns. The first form cavity is provided with a first side wall, the first side wall is provided with at least one extrusion gap, and the extrusion gap includes a first extrusion gap. The plurality of first forming columns are arranged on the first side wall at intervals in the circumferential direction of the first form cavity, and each of the first forming columns protrudes towards the interior of the first form cavity, such that a first extrusion gap is defined between each two adjacent first forming columns.