Abstract: Provided are salts of a compound of formula (I) having an ATX inhibitory activity. The salts comprises inorganic acid salts or organic acid salts, and solid forms of the salts, such as crystal forms. The salts of the compound of formula (I) and their crystal forms according to the present disclosure have a good solubility, stability and hygroscopicity, and are more suitable for medicinal use. Moreover, their preparation methods are simple and convenient, and are suitable for large-scale production.

Abstract: A motor control method includes: acquiring a first rotational speed error of a rotor of a motor corresponding to a current moment; acquiring a speed compensation value for the rotor according to a preset speed drop graph, which represents a graphical representation of speed versus time when a rotational speed of the rotor drops; calculating an electric current compensation value according to the speed compensation value and a preset speed-current mapping model; acquiring an electric current reference value corresponding to the current moment, which is an electric current value for controlling the rotational speed of the rotor; and controlling the motor according to the electric current compensation value if the first rotational speed error is greater than a preset error, or controlling the motor according to the electric current reference value if the first rotational speed error is less than or equal to the preset error.

Abstract: Isolated antibodies or antigen-binding fragments against Claudin-6 (CLDN6) include: chimeric monoclonal antibodies and humanized monoclonal antibodies. This application also provides conjugates, multispecific antibodies, chimeric antigen receptors, pharmaceutical compositions and kits which include the isolated anti-CLDN6 antibodies or the antigen-binding fragments. The disclosed antibodies or the antigen-binding fragments can be used for diagnosing cancer and/or determining whether cancer cells express CLDN6, as well as for treating and/or preventing various cancers or diseases associated with cells expressing CLDN6 in subjects.

Abstract: An ion-electron mixed conductor ceramic comprises Ag-modified LLZTO ceramic; a preparation method of the ion-electron mixed conductor ceramic includes the following steps: adding LLZTO ceramic into a solution containing a soluble silver salt and a reducing agent to obtain silver oxide, and reacting the silver oxide under the action of the reducing agent to prepare the Ag-modified LLZTO ceramic; a composite solid electrolyte comprises the aforementioned ion-electron mixed conductor ceramic, a lithium salt and a polymer; a battery electrode material comprises the aforementioned ion-electron mixed conductor ceramic; a battery comprises the aforementioned ion-electron mixed conductor ceramic or the aforementioned solid electrolyte; when the modified ceramic is applied in electrode materials, it can simultaneously play a role in transporting electrons and ions, improve electrode kinetics, and has good application prospects in the battery field.

Abstract: This application discloses a blockchain-based data processing method performed by a computer device. The method includes: in response to a selection operation of media elements associated with a target object, acquiring a target media element combination based on the selected media elements; in response to a virtual resource creation operation for the target media element combination, generating target combined media data corresponding to the target media element combination; and transmitting a virtual resource creation request for the target combined media data to a blockchain network, wherein the blockchain network creates a target on-chain virtual resource corresponding to the target combined media data after determining that the target combined media data passes duplicate check and verification, and an ownership right of the target on-chain virtual resource belonging to the target object.

Abstract: An aerosol generating substrate, an aerosol generating article, and an electronic atomizing device are provided. The aerosol generating substrate includes a base part and a plurality of subparts, the plurality of subparts are located at an outer side of the base part in a first direction, the plurality of subparts are spaced apart from each other in a second direction of the base part, and a space between any two adjacent subparts of the plurality of subparts is a gap space, in which the first direction and the second direction intersect with each other.

Abstract: This invention relates to genetically improved Eastern oyster (Crassostrea virginica) lines developed by the Morgan State University Patuxent Environmental and Aquatic Research Laboratory. Derived from Maryland wild populations, these diploid, triploid, and tetraploid lines exhibit enhanced tolerance to low salinity, rapid growth, and disease resistance. Genetic improvement was achieved through multiple approaches including phenotype-based, genomic, and marker-assisted selection. Several diploid low-salinity-tolerant lines (LS2019, LS2025, LS H-GEBV) and a fast-growing line (FG H-GEBV) have been produced and are undergoing field evaluation, while MSX-resistant lines are under development through field challenge testing. Multi-trait genomic selection enables integration of growth, salinity tolerance, and disease resistance into single lines based on trait correlations and production needs.

Abstract: A method and system for image acquisition may be provided. A first exposure duration of a first image sensor and a second exposure duration of each of at least one second image sensor may be obtained. For each second image sensor, a synchronization time difference between the first image sensor and the second image sensor may be determined based on an exposure duration difference between the first exposure duration and the second exposure duration of the second image sensor, and first image data and second image data from the first image sensor and the second image sensor may be acquired by sending synchronizing signals to the first image sensor and the second image sensor based on the synchronization time difference. A target image of the target scene may be generated based on the first image data and the second image data of each second image sensor.

Abstract: This invention relates to the development of heat-tolerant soft-shell clam (Mya arenaria) lines for aquaculture through selective breeding and molecular genetic approaches. Two methods are employed: (1) phenotype-based selection, in which clams are exposed to natural or controlled heat shock conditions (30-33° C.) and survivors are selected across successive generations and multiple populations; and (2) marker-assisted selection (MAS), utilizing single nucleotide polymorphisms (SNPs) identified through genome-wide association studies (GWAS) to select broodstock capable of producing heat-tolerant offspring. The resulting lines exhibit enhanced survival and endurance under elevated temperatures, particularly above the species' critical threshold of 28° C. These heat-tolerant clams enable sustainable aquaculture production in Maryland and other warm, low-salinity estuaries where soft-shell clams historically failed to survive summer heat.

Abstract: An extrusion mold for fabricating an aerosol-generating article is provided. The extrusion mold includes a first form cavity and a plurality of first forming columns. The first form cavity is provided with a first side wall, the first side wall is provided with at least one extrusion gap, and the extrusion gap includes a first extrusion gap. The plurality of first forming columns are arranged on the first side wall at intervals in the circumferential direction of the first form cavity, and each of the first forming columns protrudes towards the interior of the first form cavity, such that a first extrusion gap is defined between each two adjacent first forming columns.

Abstract: A solid electrolyte, a method for manufacturing the solid electrolyte, and a battery are disclosed. The solid electrolyte includes a polymer, a silver salt, and an alkali metal salt. When the solid electrolyte provided in the present disclosure is matched with a metal such as lithium metal, a gradient SEI layer rich in inorganic components can be in-situ generated during electrochemical cycling. The gradient SEI layer includes an outer layer rich in silver-containing inorganic components and an inner layer rich in lithium-containing inorganic components. Thus, the battery possesses high ionic conductivity and stability against the lithium metal anode, and the in-situ constructed SEI layer can uniformize lithium ion deposition, inhibit lithium dendrite growth, realize stable cycling under high current, and exhibit excellent low-temperature electrochemical performance.

Abstract: An oral care device includes a handle housing, a care element, and an energy receiving module. The handle housing includes an end shell portion and a peripheral shell portion. The peripheral shell portion is disposed at a first end of the end shell portion. The end shell portion and the peripheral shell portion jointly define an accommodating space. The energy receiving module is disposed in the accommodating space and is disposed on one side where the end shell portion is located. The energy receiving module faces the end shell portion, so that at least a portion of the care element is located within an energy receiving range of the energy receiving module. The energy receiving module is configured to receive at least part of energy reflected by at least one of the care element and a human body feature outside an oral cavity.

Abstract: A method for preparing a silver paste includes creating a mixture of succinic acid, 1-butoxy-2-propanol, terpineol, ethanol, and ethylene glycol; ultrasonically mixing the mixture for a first predetermined period; adding silver particles; and mechanically stirring the mixture for a second predetermined period to create a silver paste.

Abstract: The present disclosure relates to a field of memory technical, and in particular to a magnetoresistive device, a method for changing a resistance state of the magnetoresistive device, and a synapse learning module. The magnetoresistive device includes a top electrode, a ferromagnetic reference layer, a tunneling layer, a ferromagnetic free layer, a spin-orbit coupling layer, and a bottom electrode that are arranged in sequence along a preset direction, where the spin-orbit coupling layer includes a first thickness region and a second thickness region distributed alternately, and a thickness of the first thickness region is different form a thickness of the second thickness region; and the ferromagnetic free layer includes a pinning region, and a position of the pinning region is in one-to-one correspondence with a position of the first thickness region.

Abstract: The ester derivatives of brefeldin A represented by Formula (I) in the inhibition of tumor proliferation. The compounds are prominent in the prevention or treatment of hyperproliferative diseases, including liver cancer, leukemia, breast cancer, colon adenocarcinoma, gastric cancer, lung cancer, Bart's esophageal cancer, cervical cancer, pancreatic cancer, endometrial cancer, bone cancer, lymphoma, kidney cancer, brain cancer, nerve cancer, nasopharyngeal cancer, oral cancer and colorectal cancer, and have the potential to be developed as antitumor agents.

Abstract: A power device is provided, which includes a driving motor connected to a main control module. Front and rear ends of the driving motor are provided with synchronous rotating main driving shafts. The main driving shafts indirectly drive driven shafts, a clutch device is provided between the main driving shafts and the driven shafts and drives the driven shafts and the main driving shafts to rotate according to a rotation direction of the main driving shafts. Rotating propellers for pushing water are provided on the driven shafts. Compared with existing technology, the power device has main driving shafts extending from two ends of the driving motor. The forward and reverse rotation of the driving motor respectively drives the corresponding rotating propellers on the driven shafts to rotate, discharge water flow, generate reverse thrust, and achieve forward and backward movement. The structure is simple and reduces volume.

Abstract: A cooling system includes a housing including a base portion with sides and a bottom surface that define a cavity and a cover portion to enclose the base portion and including cooling members attached thereto. A shield is arranged in the cavity. A vertical member is arranged below the shield to define a first fluid chamber between one side of the vertical member and one side of the base portion and a second fluid chamber between an opposite side of the vertical member and another side of the base portion. The electronic components are arranged in the second fluid chamber. Cooling fluid is arranged in the cavity and has a fluid level below at least a portion of the shield. The housing is mounted at an inclined angle relative to horizontal or the housing is mounted parallel to horizontal and the shield is mounted at the inclined angle.

Abstract: The present disclosure discloses an anti-Claudin 6 antibody and an antibody-drug conjugate. The present disclosure relates to an antigen sequence for preparing the Claudin 6 (CLDN6) antibody, a corresponding nucleotide sequence thereof, and a gene engineering vector, engineering bacterium or cell line for expressing the nucleotide sequence. A highly specific CLDN6 antibody may be produced by immunizing an animal with the antigenic polypeptide. Further, a corresponding monoclonal antibody may be obtained by preparing a hybridoma cell with a cell of the immunized animal. The anti-Claudin 6 antibody may be combined with a linking structure and a drug to form an antibody-drug conjugate. The antibody-drug conjugate may deliver the drug to a tumor cell having a positive expression of CLDN6 depending on the targeting effect of the CLDN6, thereby achieving the efficacy of specifically killing the tumor cell, which is of great significance for the treatment of the tumor.

Abstract: A display substrate and a manufacturing method therefor, and a display device. The display substrate comprises a plurality of island areas that are spaced apart from each other, a plurality of hole areas, and bridge areas for connecting adjacent island areas. The island areas or/and the bridge areas comprise an edge area adjacent to the hole area; the edge area comprises a composite structure layer provided on a base substrate; a stepped structure is formed at a side surface of the composite structure layer facing the hole areas; the edge area further comprises an inorganic encapsulation layer disposed on the composite structure layer and the stepped structure.

Abstract: A HfO2-based ferroelectric capacitor and a preparation method therefor, and a HfO2-based ferroelectric memory, relating to the technical field of microelectronics. The purpose of enlarging the memory window of the ferroelectric memory is achieved by inserting an Al2O3 intercalation layer having a coefficient of thermal expansion smaller than TiN between a dielectric layer and an upper electrode (TiN) of the ferroelectric capacitor. The HfO2-based ferroelectric capacitor comprises a substrate layer, a lower electrode, a dielectric layer, an Al2O3 intercalation layer, an upper electrode and a metal protection layer from bottom to top. The memory window can be increased, information misreading is effectively prevented, and therefore, the reliability of the memory is improved.