Patents by Inventor Motoo Yamasaki

Motoo Yamasaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF MODULATING THE ACTIVITY OF FUNCTIONAL IMMUNE MOLECULES
    Publication number: 20100196371
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Application
    Filed: December 23, 2009
    Publication date: August 5, 2010
    Applicant: KYOWA HAKKO KIRIN, LTD.
    Inventors: NOBUO HANAI, KAZUYASU NAKAMURA, EMI HOSAKA, MOTOO YAMASAKI, KAZUHISA UCHIDA, TOYOHIDE SHINKAWA, SUSUMU IMABEPPU, YUTAKA KANDA, NAOKO YAMANE, HIDEHARU ANAZAWA
  • Method of modulating the activity of functional immune molecules to platelet-derived growth factor receptor
    Patent number: 7763246
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: July 27, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE
    Publication number: 20100172967
    Abstract: Objects of the present invention are to provide a compound which is useful as a surface modifier for producing a drug carrier or the like, or a salt thereof; a fine particle comprising the same; and the like.
    Type: Application
    Filed: February 19, 2010
    Publication date: July 8, 2010
    Applicants: KYOWA HAKKO KIRIN CO., LTD., TECHNO NETWORK SHIKOKU CO., LTD.
    Inventors: Hisao Nemoto, Masahiro Yamauchi, Hiroko Kusano, Yasuki Kato, Motoo Yamasaki, Toshiyuki Suzawa
  • Antibody composition exhibiting increased cellular cytotoxicity due to glycosylation
    Patent number: 7741442
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: June 22, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Antibody composition-producing cell
    Patent number: 7737325
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-modulated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: June 15, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Antibody Composition-Producing Cell
    Publication number: 20100143388
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: November 30, 2009
    Publication date: June 10, 2010
    Applicant: KYOWA HAKKO KIRIN CO., LTD
    Inventors: YUTAKA KANDA, MITSUO SATOH, KAZUYASU NAKAMURA, KAZUHISA UCHIDA, TOYOHIDE SHINKAWA, NAOKO YAMANE, EMI HOSAKA, KAZUYA YAMANO, MOTOO YAMASAKI, NOBUO HANAI
  • Method of modulating the activity of functional immune molecules to interleukin-5 receptor protein
    Patent number: 7718175
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: May 18, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Method of modulating the activity of functional immune molecules
    Patent number: 7708997
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: May 4, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Methods for producing antibody compositions with increased ADCC
    Patent number: 7708992
    Abstract: The invention relates to methods for modulating the antibody-dependent cellular cytotoxicity of an IgG antibody composition.
    Type: Grant
    Filed: May 11, 2005
    Date of Patent: May 4, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Compound modified with glycerol derivative
    Patent number: 7696359
    Abstract: Objects of the present invention are to provide a compound which is useful as a surface modifier for producing a drug carrier or the like, or a salt thereof; a fine particle comprising the same; and the like.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: April 13, 2010
    Assignees: Kyowa Hakko Kirin Co., Ltd., Techno Network Shikoku Co., Ltd.
    Inventors: Hisao Nemoto, Masahiro Yamauchi, Hiroko Kusano, Yasuki Kato, Motoo Yamasaki, Toshiyuki Suzawa
  • Branched polyalkylene glycols
    Patent number: 7691367
    Abstract: The present invention provides branched polyalkylene glycols useful as a chemically modifying agent for physiologically active polypeptides, wherein two single-chain polyalkylene glycols are linked to a group having a cyclic structure other than a plane structure, and wherein a group having reactivity with an amino acid side chain, an N-terminal amino group or a C-terminal carboxyl group in a polypeptide or a group convertible into the group having reactivity is linked to the group having a structure other than a plane structure.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: April 6, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Motoo Yamasaki, Toshiyuki Suzuwa, Tatsuya Murakami, Noriko Sakurai, Kinya Yamashita, Mayumi Mukai, Takashi Kuwabara, So Ohta, Ichiro Miki
  • Method of modulating the activity of functional immune molecules to Her-2
    Patent number: 7687061
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: March 30, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • NOVEL PEPTIDES
    Publication number: 20100075343
    Abstract: The present invention provides novel peptides with energy-modulating activity or circulatory function-modulating activity. The peptides of the present invention have energy-modulating activity or circulatory function-modulating activity and thus are useful for treating food consumption disorders and diseases of the circulatory system.
    Type: Application
    Filed: November 29, 2007
    Publication date: March 25, 2010
    Inventors: Motoo Yamasaki, Noriyuki Takahashi, Naoto Minamino, Kazuki Sasaki, Toshifumi Takao, Yoshinori Satomi, Yoichi Ueta
  • Method of modulating the activity of functional immune molecules to CXCR4 protein
    Patent number: 7682611
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: March 23, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Method of modulating the activity of functional immune molecules
    Patent number: 7682610
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: March 23, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Method for treating Th2-mediated disease
    Patent number: 7666418
    Abstract: A recombinant antibody or the antibody fragment thereof which specifically reacts with an extracellular domain of human CCR4; a DNA which encodes the recombinant antibody or the antibody fragment thereof; a method for producing the recombinant antibody or the antibody fragment thereof; a method for immunologically detecting CCR4, a method for immunologically detecting a cell which expressed CCR4 on the cell surface, a method for depleting a cell which expresses CCR4 on the cell surface, and a method for inhibiting production of Th2 cytokine, which comprise using the recombinant antibody according or antibody fragment thereof; a therapeutic or diagnostic agent for Th2-mediated immune diseases; and a therapeutic or diagnostic agent for a blood cancer.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: February 23, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Kenya Shitara, Nobuo Hanai, Emi Shoji, Mikiko Sakurada, Akiko Furuya, Kazuyasu Nakamura, Rinpei Niwa, Kenji Shibata, Motoo Yamasaki
  • Method of modulating the activity of functional immune molecules to GM2
    Patent number: 7655228
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: February 2, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Method of modulating the activity of functional immune molecules to CD52
    Patent number: 7651688
    Abstract: The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: January 26, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Nobuo Hanai, Kazuyasu Nakamura, Emi Hosaka, Motoo Yamasaki, Kazuhisa Uchida, Toyohide Shinkawa, Susumu Imabeppu, Yutaka Kanda, Naoko Yamane, Hideharu Anazawa
  • Platelet production promoting agent
    Patent number: 7592311
    Abstract: The invention relates to a polypeptide wherein at least one of the amino, carboxyl, mercapto or guanidino group in a polypeptide molecule having human granulocyte colony stimulating factor activity is chemically modified by a chemical modifying agent, and a platelet production promoter comprising said polypeptide, a method for treating a patient with decreased platelet counts comprising administering an effective amount of said polypeptide to the patient, the use of said polypeptide for the production of pharmaceutical compositions which are useful for the treatment of the patient with decreased platelet counts, and the compositions for treating the patient with decreased platelet counts, which comprises an effective dose of said polypeptide in a pharmaceutically acceptable dosage form with a pharmaceutical acceptable carrier.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: September 22, 2009
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Motoo Yamasaki, Masami Okabe, Toshiyuki Suzawa, Ken Kobayashi, Kumiko Maruyama
  • Antibody Composition-Producing Cell
    Publication number: 20090228994
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: March 24, 2009
    Publication date: September 10, 2009
    Applicant: KYOWA HAKKO KOGYO., LTD.
    Inventors: Yutaka KANDA, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai