Abstract: Provided are a proline hydroxylase and uses thereof. The proline hydroxylase comprises having the amino acid sequence of SEQ ID NO: 2 with the exception of a mutation of one or more amino acids; wherein the mutation of one or more amino acids must comprises E27K, and the mutation of one or more amino acids selected from the group consisting of: H14R, L16N, T25R, F26L, E27K, D30S, S33N, E34N, E34G, E34L, E34S, E34D, Y35W, Y35K, S37W, S37F, S37E, S37N, S37T, S37C, W40F, K41E, D54G, H55Q, S57L, I58T, I58Y, I58A, I58R, I58V, I58S, I58C, K86P, T91A, F95Y, C97Y, I98V, K106V, K106T, K106Q, F111S, K112E, K112R, S154A, K162E, L166M, I118F, I118V, I118R, H119R, H119F, I120V, K123D, K123N, K123Q, K123S, K123I, K123T, T130N, D134G, V135K, N165H, D173G, K209R, I223V and S225A, and having proline hydroxylase activity.

Abstract: The present disclosure provides a touch display device which includes a display panel and a flexible circuit board coupled to the display panel. The flexible circuit board includes a display functional region and a touch functional region, the display functional region is coupled to a control mainboard of the touch display device via a first connector, and the touch functional region is coupled to the control mainboard of the touch display device via a second connector.

Abstract: The present application relates to a display device. The display device includes a flexible display panel including display and back surfaces in a thickness direction thereof; a supporting back film located on the back surface, and including a bendable area and fixed areas located at opposite sides of the bendable area in a first direction; and an adhesive part located between the fixed area and the back surface, and adhered to the fixed area and the back surface; and a flexible supporting part located between the bendable area and the back surface, and being in contact with the bendable area and the back surface. The flexible supporting part is in direct contact with the back surface of the flexible display panel.

Abstract: Described herein are a PVA membrane immobilized enzyme and a preparation method therefor. The PVA membrane immobilized enzyme includes a PVA porous membrane and an enzyme entrapped on the PVA porous membrane. The PVA porous membrane is a three-dimensional structured PVA porous membrane. The enzyme is any one selected from transaminase, D-lactate dehydrogenase, cyclohexanone monooxygenase, ketoreductase, alkene reductase, nitrilase, ammonia lyase, amino acid dehydrogenase, imine reductase, alcohol dehydrogenase, ammonium formate dehydrogenase, glucose 1-dehydrogenase and mutants thereof. The three-dimensional structured PVA porous membrane is used as a carrier to immobilize an enzyme in an entrapment manner. After entrapping and immobilizing the enzyme in the PVA porous membrane, the enzyme is stable, and cannot be easily leached out in the process of use. The PVA porous membrane is suitable for use in continuous flow biochemical catalysis, and has wide applicability to enzymes.

Abstract: Provided is an immobilized enzyme, a preparation method and use thereof. The immobilized enzyme includes an enzyme and an amino resin carrier for immobilizing the enzyme, and the enzyme is selected from any one of the following enzymes: transaminase, ketoreductase, monooxygenase, ammonia-lyase, ene reductase, imine reductase, amino acid dehydrogenase, and nitrilase. The amino resin carrier is an amino resin carrier modified by a cross-linking agent, and the cross-linking agent is a cross-linking agent treated by a polymer. By means of modifying the amino resin carrier with the cross-linking agent treated by the polymer, the enzyme immobilized on the amino resin carrier may easily form a network cross-linking, such that the immobilization effect of the enzyme is more stable, thereby the recycling efficiency of the enzyme is improved.

Abstract: A chest and abdomen coupled cardiopulmonary resuscitation device, including a bottom plate and at least two compression/traction mechanisms, wherein each of the two compression/traction mechanisms includes two linear motors with opposite positions, the axes of the two linear motors are perpendicular to the bottom plate, and the bottoms of the linear motors are in slip connection with the bottom plate; and the tops of the two linear motors are fixedly connected by a connecting mechanism, the bottom of the connecting mechanism is fixedly provided with a presser connected to an air pump, and the presser can move on the connecting mechanism along a direction perpendicular to the sliding direction of the linear motors. The device can be adjusted to the optimal compression frequency, depth and duration according to objective physiological indicators, thereby greatly improving success rate of rescue.

Abstract: The present application relates to a method and system for generating multi-task learning-type generative adversarial network for low-dose PET reconstruction, and relates to the field of deep learning. The method includes connecting layers of the encoder with layers of the decoder by skip connection to provide a U-Net type picture generator; generating a group of generative adversarial networks by matching a plurality of picture generators with a plurality of discriminators in one-to-one manner; obtaining a first multi-task learning-type generative adversarial network; designing a joint loss function 1 for improving image quality; and training the first multi-task learning-type generative adversarial network according to the joint loss function 1 in combination with an optimizer to provide a second multi-task learning-type generative adversarial network.

Abstract: Devices, systems and methods for digital video coding, which include geometric partitioning, are described. An exemplary method for video processing includes making a decision, based on a priority rule, regarding an order of insertion of motion candidates into a motion candidate list for a conversion between a current block of video and a bitstream representation of the video, wherein the current block is coded using a geometry partition mode; and performing, based on the decision and the motion candidate list, the conversion.

Abstract: A cylinder porous cylinder, a gas flow control valve, and a mounting method for the gas flow control valve. The porous cylinder (1) includes a plurality of pipe bundles filled inside the pipe. A single flow passage is formed in each of the pipe bundles, such that a seepage passage is formed inside the pipe. The inner diameter, length and permeability of the pipe bundle are determined in advance based on a Reynolds number smaller than 2300. The porous cylinder (1) is capable of implementing a stable gas flow in a gas injection channel. The valve body (21) of the gas flow control valve (2) is provided therein with a plurality of tubular passages arranged in sequence along the horizontal direction of the valve body. The tubular passages include a pipe flow passage (24) and a plurality of seepage passages (25). The porous cylinder (1) is mounted in each of the seepage passages (25). A plurality of connection channels (221) are provided in the valve cap.

Abstract: Provided is a ketoreductase mutant and applications thereof. Compared with an amino acid sequence shown in SEQ ID NO: 1, the amino acid sequence of the ketoreductase mutant includes at least one of the following mutation sites: L198P, S96W/I/L/V, M194L or L1526, herein “/” means “or.” The ketoreductase mutant provides high selectivity and high activity with respect to a substrate ketone, and the application of the mutant in a catalytic reduction reaction of a ketone substrate may increase the production efficiency of a chiral alcohol compound corresponding thereto.

Abstract: Provided are a transaminase mutant and an application thereof. Compared with an amino acid sequence shown in SEQ ID NO:1, an amino acid sequence of the transaminase mutant includes at least one of the following mutation sites: L166, K149, K146, A168, H73, F133, H82, E24, V194, T294, A295, G235 and F236. The mutant of the present invention has the improved catalytic activity for a transammonization reaction of ketone substrates, and is suitable for industrial production of chiral amines.

Abstract: A video processing method includes determining, for a conversion between a current video block of a video including multiple video blocks and a coded representation of the video, and from types of reference pictures used for the conversion, applicability of a coding tool to the current video block and performing the conversion based on the determining. The method may be performed by a video decoder or a video encoder or a video transcoder.

Abstract: Provided are a transaminase mutant and use thereof. The transaminase mutant has an amino acid sequence obtained by mutation of an amino acid sequence shown in SEQ ID NO:1, the mutation at least includes one of the following mutation site combinations: T7C+S47C, Q78C+A330C, V137C+G313C, A217C+Y252C and L295C+C328C; or the transaminase mutant has an amino acid sequence which has the mutation sites in the mutated amino acid sequence and has 80% or more identity with the mutated amino acid sequence. The transaminase mutant realizes the change of protein structure and functions, reduces the enzyme amount, increases the enantiomeric excess (ee) value of a product, and reduces the difficulty of post-processing, so that the transaminase mutant may be suitable for industrial production.

Abstract: The present disclosure provides a method and system for a dynamic fluoroscopy of a C-shaped arm device. The method comprises: photographing a subject during a photography cycle, obtaining, during the photography cycle, first fluoroscopic data of a radiation source irradiating the subject at a first energy, and obtaining second fluoroscopic data of the radiation source irradiating the subject at a second energy different from the first energy (210); photographing the subject in multiple successive photography cycles (220); and displaying a dynamic image of the subject based on the first fluoroscopic data and the second fluoroscopic data obtained in each of the multiple successive photography cycles (230).

Abstract: The present application relates to the technical field of genetic engineering, and provides a monooxygenase mutant, a preparation method and application thereof. The monooxygenase mutant has any one of the amino acid sequences shown in (I) and (II): (I) an amino acid sequence having at least 80% identity with the amino acid sequence shown in SEQ ID NO. 1; and (II) an amino acid sequence obtained by modifying, substituting, deleting, or adding one or several amino acids to the amino acids at 23 to 508 positions of the amino acid sequence shown in SEQ ID NO. 1, the substituting referring to a substitution of 1 to 34 amino acids, wherein the mutant has the activity of monooxygenase.

Abstract: The present disclosure provides a support structure and a manufacturing method thereof, and a foldable display screen. The support structure includes: a first support plate made of flexible conductive material; at least two second support plates arranged on the first support plate with interval, the second support plates being made of rigid conductive material, at least a part of surface of each of the second support plates being in contact with the first support plate.

Abstract: Disclosed are aspects of interference-aware virtual machine assignment for systems that include graphics processing units (GPUs) that are virtual GPU (vGPU) enabled. In some examples, an interference function is used to predict interference for assignment of a workload to a graphics processing unit (GPU). The interference function outputs a predicted interference to place the workload on the GPU. The workload is assigned to the GPU based on a comparison of the predicted interference to a plurality of predicted interferences for the workload on various GPUs.

Abstract: A preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile includes the following steps: step 1: in the presence of Li2CuCl4, adding a nitrochlorobenzene-zinc reagent dropwise to a 1-chlorocyclopentanecarbonitrile solution to prepare a compound 1-(4-nitrophenyl)cyclopentanecarbonitrile; and step 2: subjecting the compound 1-(4-nitrophenyl)cyclopentanecarbonitrile obtained in step 1 to a nitroreduction reaction under the action of a catalyst to prepare the compound 1-(4-aminophenyl)cyclopentanecarbonitrile. The preparation method involves cheap and easily-available raw materials, mild reaction conditions, and convenient operations, leads to high yield, and is environmentally-friendly and suitable for industrial large-scale production.

Abstract: Embodiments of the present disclosure provide methods, apparatuses and computer storage media for video processing. One example method comprises determining, during a conversion between a current video block of a video and a bitstream of the video, a set of motion candidates for the current video block; determining, for each motion candidate in the set of motion candidates, a refined motion candidate by performing a local search around the each motion candidate based on a template matching cost rule; determining, from a set of refined motion candidates generated for the set of motion candidates, a target motion candidate for the current video block; and performing the conversion based on the target motion candidate.

Abstract: Devices, systems and methods for digital video coding, which include geometric partitioning, are described. An exemplary method for video processing includes making a decision, based on a priority rule, regarding an order of insertion of motion candidates into a motion candidate list for a conversion between a current block of video and a bitstream representation of the video, wherein the current block is coded using a geometry partition mode; and performing, based on the decision and the motion candidate list, the conversion.